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Manifiesto Café is known for its wide-ranging menu of coffees and careful brewing methods. Order a cup with beans grown in Mexico, Colombia, Costa Rica, El Salvador, or a handful of varieties from Europe. No matter which coffee you choose, it will be freshly-roasted. Manifiesto doesn’t serve coffee that was roasted more than 48 hours earlier. But that’s not the owners’ only rules for the coffee they serve. They also prefer beans harvested at plantations that are about 4200 feet above sea level. If you’re looking for a quick cup of coffee, go elsewhere. Manifiesto takes its coffee very seriously and uses a variety extraction methods. The payoff? Quite easily the best cup of coffee you’ve had in a good long time.

Since 1993, Philadelphians Wendy Born and James Barrett have shown a deft hand in the kitchens of their multi-location Metropolitan Bakery. Artisanal breads – able to rival any venerated loaf from Europe– are their claim to fame but their cookies, cakes, croissants and locally-sourced jams and spreads are equally as divine. They have several locations in Philadelphia, including my favorite in Chestnut Hill a bit further afield, but consistency is assured in each outpost. You can also expect to see the duo’s vision (and baked goods) played out at FARMiCiA, the organic/local restaurant they co-own in Old City. If you have a hankering for something sweet, don’t leave without picking up one of their toothsome chocolate chip cookies (or a few).

Colombian fashion designer Silvia Tcherassi took the design world by storm when she transformed a 250-year-old mansion in the center of Old Town Cartagena into a contemporary refuge that honors both past and present. Mansion Tcherassi’s seven rooms blend fashion-forward decor (think sparkly gold throw blankets) and original features such as restored stone walls and private balconies, but the vibe is much more understated, with ethereal fabrics, soft colors, and natural wood, in the 42 neutral-hued rooms at sister property Tcherassi Hotel & Spa. You can order fresh-caught seafood and icy raspaos (traditional drinks made with fruit and condensed milk) at the restaurant, while carpaccios, pizzas, and ceviches are on the menu on the rooftop lounge; the Italian restaurant at the mansion extends to a cozy patio facing a plunge pool and vertical garden made with thousands of local plants. After a day spent exploring Old Town’s historic buildings, relax with a Chinese medicine–inspired treatment in the spa, or take a dip in one of the property’s four pools.

On a tree-studded peninsula between Monaco and Nice, this whitewashed luxury boutique hotel features 28 rooms and suites with a serenely chic vibe (think crisp white linens and richly patterned textiles, contemporary art and modern streamlined furnishings). A third of the units reside in the hotel’s main building, a mansion that dates back to 1889 but was fully restored and updated in 2003, and three additional rooms designed to resemble ship cabins are built into a wall with direct views onto the sea; the rest of the accommodations are housed in a quiet Italianate structure and a separate edifice at the edge of the property. Cap Estel’s Michelin-starred restaurant highlights seasonal ingredients, many of which are sourced from the on-site gardens. Guests who come to disconnect from the jet-set scene can relax in the hammam or waterside sauna, or with a massage and dip in the saltwater pool, though many guests would just as soon head straight into the azure waves of the Mediterranean, accessed through the hotel’s private beach.

It is not unusual to find an Arizona resort that looks like a water park with rooms attached, and this big Scottsdale luxury property certainly fits the description: 10 pools, 20 fountains, 45 waterfalls, and a three-story, high-speed waterslide. But what makes the Hyatt Regency unique is that guests can glide along its desert waterways aboard authentic Italian gondolas while being serenaded by professional gondoliers, who are classically trained singers. Beyond the water’s edge, there are the expected activities, such as the 27 holes of golf at the Gainey Ranch Golf Club, open only to club members and resort guests. And there are the unexpected, such as the Native American Learning Center, created to give guests insight into native Southwest culture through art, food, entertainment, and personal interaction with some of the resort’s staff. For hikers, the 24-hour Canyon Market serves up not only performance foods and gear, but also directions to the best trails.

One of Cape Town’s most picturesque corners, this small fishing harbor sees boats sail in daily with their catches (often trailed by hungry seals waiting for tidbits). Recently, however, the area has also become known for its antique stores, restaurants, and shops—one of the best collections of African curios, materials, and artwork for sale can be found at Artvark, on the edge of town. Expect to see everyone from hipsters to surfers to an old couple who’s lived here for 50 years. A seaside promenade connects Kalk Bay to the colorful beach cottages of St. James and to Surfers Corner in Muizenberg, another gem of an old-world suburb that is becoming a second Kalk Bay. Don’t miss Cucina Labia, a restaurant housed in a mansion built by an Italian who wanted to create a little Venice here.

To dress like the gondoliers you’ll need to pick up a pair of genuine friulane slippers at Gianni Dittura, one of the few remaining purveyors of the original footwear in Venice. Friulanes (or furlanes) were born of frugality in the 19th century, when the women of poor families in the Friuli countryside began hand-stitching cast-off fabric scraps to old bicycle tires to make shoes for their families. The slippers eventually made their way to Venice, where gondoliers snapped them up because they were cheap, comfortable, and didn’t scratch the paint on their boats. But as the years passed, friulanes inevitably went from lowly upcycled footwear to cult object and luxury product coveted by tourists. Today Gianni Dittura has two Venice shops, and you’ll find every color and size of the original velvet and rubber shoes, as well as more chic and contemporary winter models by in-house designer Laura Biagiotti.

The doorway of the Portrait Roma is one of a growing number of blink-and-you-miss-it boutique hotel entrances behind which contemporary luxuries await. Tucked behind an unassuming facade on a side street off the busy Via dei Condotti, the Portrait Roma is part of the Lungarno Collection, a small group of boutique hotels owned by the Ferragamo fashion house. Opened in 2006, the property prides itself on customized service, and each of the rooms comes with a Lifestyle Manager, or 24-hour concierge, who provides personalized holiday management throughout the stay based partly on the guest questionnaire completed before arrival.

All 14 rooms are suites, and each is classically decorated and designed to mirror the prestige of the Ferragamo brand. Rooms are accented with linen, leather, and cashmere, as well as artwork that evokes the beauty and spirit of Ferragamo. Weather permitting, the rooftop terrace hosts food and drink service and offers views of the historic center.

An understated, private landing stage for gondolas and water taxis on a side canal of the lagoon marks the entrance to the lovely Baglioni Hotel Luna in San Marco. Steeped in history, the palazzo, with lagoon-facing windows and charming Juliet balconettes, dates to the 12^th century and is said to have given refuge to the Crusade-era Knights Templar. Interiors are more in keeping with noble 18^th-century fashions. There’s a sleek marble lobby, sparkling crystal chandeliers, antique furnishings, and a healthy showing of brocade fabrics. The standout room is the pristinely preserved Salone Marco Polo, filled with18^th-century frescoes painted by pupils of influential Venetian painter and printmaker Giambattista Tiepolo.

Conveniently located just steps from bustling and culture-packed St. Mark’s Square, this hotel, with its award-winning restaurant, relaxed lounge, and rooms full of delightful period details, makes for an elegant home base in Venice.

Whether you have time to kill while waiting for your train or you simply like architecture, Milan’s main train station, Stazione Centrale, is worth a walk through for its epic 20th-century architecture. Originally designed at the turn of the century, Stazione Centrale has beautiful, monumental Liberty and Art Deco ornament in its main hall and entrances, while the platform area is covered in a gorgeous rooftop of iron arches. If you have a few more minutes, the Stazione also has some great shops, a traditional Motta caffe, and one of the best newsstands in the city.

Glo Glo Bistro is a true hidden gem in Genoa - tucked way back into a slightly sketchy piazza off of the historic Vico Lavagna. Although it looks somewhat run-down from the outside, the inside is beautifully renovated, and they have an extensive wine list to choose from. You absolutely must come for apertivo, as they have one of the most delicious ‘snack’ plates in all of town - seriously, the platters brought to your table are heaped so full with delicious bites of focaccia and cheese and chips that you will not need to spend a penny on dinner.

The winding streets of ancient Genoa all lead in one direction—straight up. Lace up your tennis shoes and keep climbing. Eventually you will reach a small park at the edge of the city, the entrance to one of the many fortresses that speckled its 17th-century walls. From here you’ll be treated to one of the best views of both old and new Genoa. Come at dusk for a stunning sunset over the urban edge of the Ligurian Sea. (And if you are too tired to walk back down, catch the funicular for less than two euros!)

Interior designer and owner Denis Roy eschewed the palapa-inspired elegance employed by so many Costa Rican resorts in favor of a tropical take on European influences—Victorian architecture, French colonial touches, and Grecian columns among them—creating a resort like no other on the country’s west coast. Owing to its vantage point 1,100 feet above the entrance to the Gulf of Nicoya, the views of the rain forest, ocean, and sunsets are stunning, especially from the infinity pool. Rooms in the main building are fairly basic, but suites and villas offer more luxurious touches, such as Jacuzzis, private ocean-facing terraces, and plunge pools. The property has its own beach (with sun beds, showers, and a snack bar), but since it’s at the bottom of a steep hill, the resort provides hourly transfers. Retreat to the open-air yoga studio, then head to the bar atop the Greek amphitheater to linger over a martini at the nightly sunset happy hour.

A 1920s townhouse in Brussels’ well-heeled Châtelain neighborhood, the intimate, Fellini-inspired Odette en Ville might as well be your fashionable Belgian friends’ pied-à-terre in the European capital. Its older sibling, Chez Odette, a landmark restaurant and inn, is hidden away in the tiny village of Williers, on the French-Belgian border, and when the Brussels iteration opened, it dressed up with all the panache of a newer arrival: a little bit flashier, a little bit sleeker, a little bit more urbane. Its marble bathrooms, dark walls, and chrome accents all feel very grown-up, but roll-top tubs, fireplaces, and vintage decor reveal those homey country roots, as does the fresh, unpretentious cuisine, including the homemade jam at breakfast. With just eight rooms, the hotel feels intimate and private, an atmosphere only enhanced by the private library, a cozy lounge (notably, adjacent to the bar) with overstuffed leather Chesterfields, vintage chess sets, shelves of art books, and a working fireplace.

Think of the Pantone Hotel as a chance to reconsider your color scheme. A sleek concept hotel with the classic white backdrop and clean-lined, retro-inspired furnishings common among European design hotels, this venture from the iconic color company and two of Belgium’s top designers and architects lives up to its name. Bold splashes of the brightest Pantone colors exist throughout. Each room is themed according to its own color (don’t worry, each is identified, so you can stock up on mugs and other Pantone swag in the hotel’s shop) and decorated with original art photography of Brussels in which the specific Pantone hue has been found. Larger rooms combine complementary shades from the Pantone spectrum. The lobby lounge is a vibrant, airy space where geometric furniture and pops of color create an updated version of a 1970s aesthetic that incorporates the building’s original architecture into the modern conceit. Most entertaining of all, the colors don’t even stop at the food: sugar packets are filled with Pantone-tinted sugar for your coffee. Talk about obsessive.