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Wynn Las Vegas, and its younger sister Encore, are known as some of the nicest properties in town, and for good reason. The suites are spacious and clean, the beds are comfortable, there is a lot of room in which to spread out and the views are stellar. Beyond the rooms themselves, the rest of Wynn is equally as beautiful, with fine art located throughout the property, very helpful staff, high-quality restaurants (all of which have at least one vegan option on the menu) and a general ambiance that feels classy, not trashy. This is a great hotel for honeymooners or couples, or for people who want a high-end Las Vegas experience that makes them feel like more than just another visitor in the city.

Since its founding in 1903, the DMA (as locals call it) has grown to become one of the top 10 largest museums in the country, with a permanent collection of over 24,000 works culled from around the globe and spanning over 5,000 years of history. Works by boldface Western names like Renoir, van Gogh, Warhol, Rothko, O’Keeffe, and Wyeth lead to extensive collections dedicated to art and antiquities from Africa, Asia, and South America; in between, limited-run exhibits might focus on Native American works, Asian textiles, or emerging contemporary artists. In addition to hosting popular events that engage the whole family, the museum is also committed to supporting Texas artists via foundations and special programs, and offers a searchable Texas artists database to help spotlight these native sons and daughters. Dine on casual, gluten-free Mediterranean fare at the plaza-side Socca, or head to the ever-popular DMA Cafe—set in a striking atrium—for globally flavored dishes inspired by works in the permanent collection.

It isn’t uncommon to see large tour buses idling in front of Merci, one of the city’s most popular home and design shops, as visitors alight, armed with canvas shopping totes and credit cards at the ready. The store’s philanthropic mission brings in droves of both tourists and locals—profits are donated to a charity in Madagascar that aids women and children. It is a veritable feel-good shopping destination. One caveat: The goods for sale don’t come cheap. While high-end homewares and designer duds don’t match all budgets, Merci’s space itself is undeniably cool. When I’m feeling strapped for cash and want the Merci experience, I head to its Used Book Café. Used books, old and new, decorate this cozy library-inspired café where I can read, write, people-watch (and play the guessing game of “What’s in that Merci bag?”), and rejuvenate with a freshly pressed lemonade. With each sip, a feeling of calm washes over me—a type of Zen harder to reach on the bustling streets of Paris. All beverages, hot or cold, are served with a bite-size piece of cake and a smile. Grab one of the mismatched vintage armchairs, the fresh scones with jam, or the American-sized lattes. But on a warm, sun-drenched Paris day, it’s the citronnade between shop-hopping that sets you right.

This 1st-century wonder will take your breath away. Not only is it one of the city’s most ancient sites, it’s been in continuous use for centuries. Originally built as a private temple, today it is a Catholic church and the resting place of Italian kings and the artist Raphael. Make the most of a wet day in Rome and watch as the rain falls through the center oculus.

Is Bar Agricole the best bar in the city? It’s certainly in the top five, based on the groundbreaking cocktail program developed by bartender and owner Thad Vogler; the award-winning architecture and interior design by local favorite Aidlin Darling; and a daring menu centered around produce from nearby organic and biodynamic farms. Vogler used to bartend in Tokyo, and his obsession with Japanese precision shows. You’ll see influences of that in the hand-cut ice cubes he uses, and in Agricole’s glassware and aprons (all from Japan). The bar stocks a limited selection of 20 or 30 spirits, almost all small batch, and with a special focus on rum. Come for drinks, come for dinner, or come for brunch: the midday menu highlights include ricotta doughnuts with quince marmalade and a chicory salad with fuyu persimmon and house-made vinegar. Pro tips: In winter, book the private dining room (nicknamed the Grotto) for a seated, though still laid-back, dinner for up to 32 people; for an outdoor event, Bar Agricole’s covered and heated patio is perfect for larger, more casual groups. For lessons in liquor, check out the private spirits tastings that Vogler offers through IfOnly.

You haven’t truly experienced Texas until you’ve visited the hallowed grounds of the Alamo. Established in 1718 as the Mission San Antonio de Valero, the building is best known as the site of the 1836 Battle of the Alamo, a 13-day siege under Mexican president General Antonio López de Santa Anna that ultimately killed nearly all of the Texan defenders. To stroll past the limestone facade and envision the battle that played out here is truly a once-in-a-lifetime experience. For a real treat, book an after-hours tour and get the Texas landmark all to yourself as you walk in the footsteps of the fallen soldiers.

Row after row of booths are sprawled across this small part of Shanghai, just south of People’s Square. Here, you can find pretty much anything you want, from tiny Mao statues, to old leather suitcases stacked 10 feet tall. Each vendor will be on you as soon as you approach their booth. They are quite polite, however, and will have a calculator or phone handy to show you the price for their items. The catch is that the majority of these “antiques” are actually factory-made items, and most booths have similar items. The good part is that you have a really good chance of a low price if you bounce back & forth between booths that have the same items. Shopping aside, this is also a great spot to see daily Shanghai life. Laundry hangs over your head, food trucks cruise up and down the rows, and the vendors socialize with each other when they are not selling items. This is a must for any visitor to Shanghai.

Spoken of in almost reverential terms by people that have traveled there, Sa Pa is often seen as a holy grail of destinations in Vietnam. Part of that is because of the environment—a cool mountain town that has lured visitors with its salubrious air and alpine scenery since the early 20th century, when the French constructed facilities for sick officers to recover—as well as its remoteness, located close to the Chinese border in the country’s extreme north. Most visitors come to Sa Pa for the hiking in the nearby valley peppered with minority-ethnic-group villages, or to climb Mount Fansipan, the country’s tallest peak, which is located just southwest of the town. Conquering the summit once required a two-to-three-day hike, but now can more easily be reached with the help of a cable car (opened in 2016) that gets you most of the way.

The history of the palaces and streets and artwork of Florence comes alive during this multimedia theater performance, acted out (in English) in a small baroque church. The show tells the story of two feuding Medici siblings—the last grand duke of the dynasty, Gian Gastone, and his sister, Anna Maria Luisa—and the patto di famiglia, or family pact, that bequeathed the family treasures to the city-state their forebears had ruled for hundreds of years. Long before there was reality television, there was family drama, Florentine style.

Northern China has some of the most amazing tasting yogurts. Since we don’t have any decent yogurt in Shenzhen, I pig out every time I go north. Stalls and shops around Xi’an sell really cool drinking yogurts. This stall was on the west side of the Giant Wild Goose Pagoda. The yogurt was perfectly tasty, though the best bit about it was the glass jars.

Located in downtown Santa Fe, this perfectly sized museum is dedicated to the artistic life of Georgia O’Keeffe (1887–1986) and houses the single largest collection of the artist’s work in the world. Rotating exhibits often include O’Keeffe’s iconic desert landscape paintings alongside lesser-known gems painted in Lake George and Hawaii (where she was commissioned by the Dole pineapple company). Often, notable pieces from established peers and contemporaries like Ansel Adams, Jackson Pollock, and Andy Warhol join hers on the walls.

Take a leisurely day trip (or a couple of days) to drive around Inishowen, the largest of Donegal’s peninsulas and enjoy the rugged scenery, with remote beaches, stone forts, castle ruins and a military museum at Dunree Head to explore. The total drive is 157km (98 miles) and you’ll find plenty of villages, cafes and pubs to stop at for food and refreshments along the way.

You’ll have the most dramatic views on your way to Malin Head at the tip—be sure to stop at the Gap of Mamore, 820 feet above sea level, for panoramic vistas of Lough Swilly and the Fanad Peninsula. Along the way you’ll also see lots of long, golden beaches and coves, sheep-filled fields, traditional cottages, and villages to stop by for lunch or refreshments. Inishowen is also home to some of Ireland’s most fascinating Christian and Gaelic sites, such as Grianan of Aileach (Grianán Ailigh in Irish), a ring fort dating back to the 6th century C.E.

A massive stretch of soft white sand calls you to the Caribbean at Cancún’s largest public beach, a quiet spot amid Hotel Zone resorts. The waves can be a bit rougher than elsewhere, so it may not be great for swimming, but the strand is one of the city’s few surfing spots. Playa Delfines also goes by the name El Mirador, thanks to its spacious hilltop deck overlooking the ocean and hotel skyline and its large, colorful “Cancún” sign that’s perfect for photo ops. Among the other welcome amenities: restrooms, a playground, small shady palapas, and an outdoor gym.

On the second Sunday of every month, bargain hunters, collectors, designers, tourists, and other curious shoppers head to the historic Rose Bowl Stadium in Pasadena, where 2,500 vendors of furniture, accessories, clothes, crafts, vinyl, and more line the perimeter of this 92,000+ seat venue. The sheer size may be overwhelming, the sun may be beating, and it may be early in the morning—but if you come prepared in sneakers, a hat, and with coffee in hand, you’ll be ready to hunt for treasure.

Kinsterna Hotel & Spa is in an 800-year-old mansion. Guestrooms feature such details as original fireplaces and Byzantine domes. The hammamlike spa was inspired by the natural springs that flow through the property.

From $234. 30/273-206-6300.

This appeared in the January/February 2013 issue.