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The Villa Necchi Campiglio, just to the east of the historic center of Milan, may look familiar. The house had a turn on the silver screen in the 2009 Italian movie “I Am Love,” starring Tilda Swinton. Even if you didn’t see the film, anyone interested in early 20th-century architecture should include this gem of Italian rationalism on their Milan itinerary. The house is named for the occupants of most of its history: the sisters Gigina and Nedda Necchi and Gigina’s husband, Angelo Campiglio. The sisters—a glamorous, cosmopolitan pair—commissioned architect Piero Portaluppi (who also designed Milan’s Museo Novecento) to build a house that was the height of fashion at the time, including such novelties as a heated outdoor pool and a tennis court. His rationalist style could be described as a no-expenses-spared modernism—simple, clean lines and rich finishes. Gleaming rosewood paneling, marble bathrooms, and customs pieces give this modernist structure an undeniable elegance. After a brief period when the home was commandeered by the Fascist Party, the sisters returned to their home. Architect Tomaso Buzzi was hired to give the villa some 19th-century touches and a less severe look, reflecting the fashion among upper-class Italians in the 1950s. Still, the home remained largely true to its original design when Gigina died in 2000 (at the age of 99) and left it to Italy‘s national trust. In 2008, it opened to the public as a museum.

The Franciscan Basilica di Santa Croce, with its striped green-and-white marble facade, dates from about 1294. Inside are the tombs of many celebrated early Florentines, including Dante, Michelangelo and Machiavelli. Among the many art treasures are radiant frescoes by Giotto and his pupil Taddeo Gaddi, which decorate the Bardi and Peruzzi chapels, and the newly restored Cappella dei Pazzi, a Renaissance architectural masterpiece designed by Brunelleschi.

Often referred to as Belize‘s original eco-lodge, Chaa Creek opened in 1981 as a simple rain forest hotel. In the decades since, it has become one of the country’s most popular options for upscale jungle accommodations, winning awards for its hospitality and its practices emphasizing environmental sustainability. Guests have two main options in terms of room types and price points. Luxurious rooms and suites are in the main lodge, featuring polished wood or tile floors and locally made furniture; the simpler, more budget-friendly casitas sit along the Macal River. The latter are sparsely furnished and offer few distractions. Guests of either room type have access to the property’s amenities and grounds, which include a natural history center and butterfly exhibit, a rain forest medicine trail, binoculars for bird-watching, and canoes for paddling along the river.

Built in the style of a desert fortress near an endurance horseracing center 45 minutes from the city of Dubai, the family-friendly Bab Al Shams Desert Resort & Spa wraps around an oasis and looks out over gently rolling sand dunes that guests explore by 4x4, horse, camel, and mountain bike. Rooms with private balconies or garden patios cluster in double-story buildings that surround courtyards, shaded corridors, and infinity pools. Stone bathtubs, wood furniture, chests, kelims, colorful textiles, and a reproduction spice souk create a Disney-meets-Bedouin lifestyle setting. For peace and quiet, stay during the week, since the main restaurant fills on weekends with locals and bus tours.

The Elliott Bay Book Company is the Seattle bookstore and, thankfully, survived its move from Pioneer Square to Capitol Hill with soul and towering cedar bookcases intact. Elliott Bay lost a significant chunk of square footage during the move but gained a home right in the heart of Capitol Hill. Which makes it even easier to execute the ideal lazy Sunday afternoon combo: new novel + Fonte latte and one of the book-size housemade muffins from the on-site café (if it’s sunny, make a beeline for the grassy Cal Anderson park, just across the street). The food is northwest downhome—unpretentious salads with local greens, wholesome soups—but the abundant outlets and cozy café vibe make up for any food misses.

Try it there: The lemon crepe

Bring it home: Thomas Pynchon’s Inherent Vice and tickets to a Neptune Theater reading

This archipelago off the coast of La Paz (which takes the name of the main island) is a protected UNESCO Biosphere Reserve. While the islands are uninhabited by humans save for a small fishing camp made of temporary structures, they’re home to a great variety of flora and fauna. In addition to dolphins, frigate birds, and ring-tailed cats, you’ll find the only known black jackrabbit population in the world. Celebrated eco-friendly activities company Cabo Expeditions leads daylong archipelago tours that include exploring the mesmerizing volcanic landscape, a ceviche lunch, and an opportunity to swim on Ensenada Grande Beach—often cited as one of the world’s most beautiful—plus guided snorkeling with the incredibly playful pups at the Los Islotes sea lion colony.

In 2016, Ace added another link to its chain of ultracool hotels when it opened an outpost in a renovated 1928 building in the Central Business District of New Orleans. While the Ace employees here are just as edgy as their counterparts elsewhere, they temper that cool with the warm ease of New Orleans’s locals.

Guests enter the hotel through a lobby of mismatched low-slung sofas and vintage coffee tables set in conversation-friendly groupings beside a lovely and ornate wooden bar. Most of the furnishings and artwork complement the hotel’s dominant forest green hue, which itself seems to have been inspired by the color of the streetcars that trundle past on Carondelet Street. Afternoon and evening and late at night, the lobby bar is kept busy by hotel guests as well as a stream of others drawn here by the stylish vibe.

Marilyn Monroe once proclaimed that her favorite swimming pool was at the Arizona Biltmore. And Irving Berlin, obviously a person who didn’t know how to relax, is said to have written “White Christmas” while a guest at the hotel. Other musical guests have included Frank Sinatra and Sammy Davis Jr., who were known to play on a piano in the lobby. But that’s history, and the Jewel of the Desert, as the 90-year-old hotel was once known, is now just one more sparkling gem in a treasure chest of Arizona resorts. To continue shining, the Biltmore underwent a major renovation that was completed in late 2016. Much of the update focused on restoring the hotel’s original main building, but the guest rooms, meeting spaces, ballrooms, and spa were also polished. The contemporary style that now dominates the Biltmore was inspired by Frank Lloyd Wright, who played a significant role in determining the hotel’s original look. In the guest rooms, Wright’s influence is most notable in the wall coverings, embossed with a design similar to that found on his “Biltmore Blocks,” used in the construction of most of the resort. Of course, for guests who didn’t come for the history, or the design lecture, there are still the eight swimming pools, seven tennis courts, and, next door at the Arizona Biltmore Golf Club, 36 holes of golf.

Owned by the world-renowned art collector Dakis Joannou and smartly decorated by quirky Brazilian designers the Campana brothers, the New Hotel is the city’s coolest upscale design-centric property, with 79 rooms (including seven suites) and an intimate restaurant. Although centrally located, just a five-minute walk to Syntagma Square, it’s tucked back in a modernist building on a side street so it feels hidden and discreet. The interiors are both playful and smart; the Campanas created much of it with items recycled from the previous hotel. Imagine puzzlelike walls and chairs constructed of layered, repurposed wood intermingled with sculptural chairs of their own design. In the rooms, they had fun riffing on Greek cultural objects, like the Karagiozis, a shadow puppet, and multiple versions of the glass “evil eyes” used to protect against ill omen. Bottom line: stylish contemporary design, excellent location, and friendly service.

I love all of the McMenamins properties I’ve stayed at over the years on travel through the Pacific Northwest, but I may have a new favorite: McMenamins Edgefield in Troutdale, right at the western mouth of the Columbia River Gorge. As always, the hotel honors the past of the building it now resides in, it has great food and drink, and every inch is covered in whimsical art that demands you have a good time. Historic Edgefield was built in 1911 as the county poor farm, and it’s now a 74-acre hotel and playground, home to award-winning farm-to-table cuisine, a winery, a brewery, three pubs, movie theater, golf course, you name it. With 100 guest rooms and hostel accommodations, the instant you step on the grounds you’ll be able to tell that community and creativity are cherished here. If you’re traveling solo or out on a long trip and looking to save some money on the hotel part, I’d encourage you to look at their rooms that don’t have a private bathroom en suite. Instead, you head to the large, comfy, and private communal restrooms to get cleaned up. Brilliant. This is a great spot to launch your explorations along the Columbia River Gorge, and if you live in the Portland area, it’s a great place to gather for a weekend bike ride, grub with fellow friends, and a few cold pints around the outdoor fire pits when things get cold. With films and live music nightly, it’s hard not to want to just live here forever.

The California Academy of Sciences is an unfortunately stuffy name for an institution that is anything but staid. The country’s largest natural-history museum includes an aquarium, a planetarium, an enormous rain-forest exhibit under a 27-meter-tall (90-foot-tall) dome, and a living roof that looks like a science-fiction fantasy. A visit here can feel like a trip to an amusement park, with a series of attractions to check out, but all of them are educational. The building itself is part of the appeal of the Academy. (Like the nearby de Young, the old home of the California Academy of Sciences was damaged in the 1989 Loma Prieta earthquake, and starchitect Renzo Piano designed its very environmentally friendly replacement.) It would be easy to spend an entire day or more seeing all of the Academy’s exhibits, so be prepared to pick and choose among them.

If you happen to be meandering through Budapest, and have the urge to do a little sightseeing, St. Stephen’s Basilica is definitely a sight to see. The structure is named in honor of Stephen, the first king of Hungary. Apparently, his right hand is also housed here, but fortunately I did not come across it during my explorations. What I did come across, and what will greet you upon entering, is a dazzling array of multicolored marble columns that soar to the heavens. What is not carved in relief on the walls is gilded in gold on the ceilings. The intricacy of the floor and the meticulous attention to detail will almost make you forget to look up. Ah, but when you do, what a sight to behold! The dome of St. Stephen’s is probably one of the more awe-inspiring views in Budapest. Natural light spills in from the etched windows to illuminate the works of art that seem to float above you, all while being surrounded by an inordinate amount of gold leaf. The visual masterpiece almost makes you want to clap - it makes you want to give King Stephen a hand.

One of the best views of Florence can be savored from the Piazzale Michelangelo, a short walk across the Arno River from downtown Florence. For a fun afternoon head to the square and enjoy an enchanting panorama of the city, followed by a relaxing alfresco lunch at one of the nearby restaurants. The Piazzale Michelangelo is also worth a visit at night to get a very different glimpse of Florence. The lights of the Duomo and the buildings surrounding it make for a magical nighttime scene.

Napoléon and his armies marched through it; revolutionaries and Nazis gathered beneath it; the Berlin Wall ran right behind: It’s safe to say that Berlin’s iconic Brandenburg Gate, completed in 1791, has pretty much seen it all. Designed by Carl Gotthard Langhans, who drew inspiration from the entrance to the Acropolis in Athens, the gate is best approached via Unter den Linden, the tree-lined boulevard that runs between the gate and the former Royal Palace. You can combine a visit here with nearby sights such as the Reichstag, Tiergarten Park, and the Memorial to the Murdered Jews of Europe. Since 2016, an impressive high-tech museum at the gate has offered a history of the city through the perspective of the iconic structure.

Restored to its former glory in 2008, the Italianate Westin Book Cadillac Detroit in Downtown is on the National Register of Historic Places and has 453 neutral-toned guest rooms—all with city or Detroit River views—an indoor pool, and an award-winning restaurant.