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The English novelist D.H. Lawrence came to New Mexico to recuperate after being diagnosed with tuberculosis. This 160-acre ranch, gifted to him by Mabel Dodge Luhan, is where he started work on his novel The Plumed Serpent. He wrote underneath a tall ponderosa pine, immortalized by Georgia O’Keeffe in her painting The Lawrence Tree. Take a tour of Lawrence’s estate, including the famous tree, “standing still and unconcerned and alive,” as Lawrence once wrote.—By Edmund Vallance

Set along the sacred Ayung River, Four Seasons Resort at Sayan is a tropical paradise shrouded in giant palms and ferns. Designed by John Heah, the property was built and decorated using regional materials almost exclusively, from shells and coconuts to coveted ikat fabrics, giving guests an authentic Balinese experience just 15 minutes from Ubud. A serene lotus pond sits on the rooftop of the resort’s main building, and teakwood villas offer views of rice terraces and the longest river in Bali. Indonesian cooking classes, ancient wellness rituals, and plantings with local rice farmers are just some of the ways guests can connect with the local culture; the rest can be found in Ubud, where vibrant markets, temples, and museums counterbalance the hotel’s tranquil dining and wellness journeys.

Little-known fact: New Orleans was the first place in North America to license pharmacists (starting in 1769, when the city was still under Spanish rule). After Louisiana became a territory, the U.S. governor extended the requirement, also decreeing that pharmacists take a three-hour licensing exam in order to practice. And no wonder illness got such attention—the city was arguably the least healthy place to live on the continent; it was riddled with yellow fever, malaria, and dysentery. This dark but fascinating history is explored in this atmospheric 1822 town house, which was once the home and shop of Louis J. Dufilho, the first licensed pharmacist in the city—and hence in the country. Exhibits include apothecary jars, tools of the trade, and leeches. (Yes. Leeches.)

The ancient Greeks called Folegandros “iron hard,” but this Cycladic island has a mellow soul beneath its edges. The northern part is the wildest, where locals still scrabble a living making cheese from their goats, threshing grain with mules, and fishing off translucent bays. At homestead tavernas (like Eirini’s grocery-cum-eatery in Ano Meria), the owners rear or grow everything they serve. The main village, Chora, is huddled on a cliff 650 feet above the sea, but the emerald water below is so clear you can count the fish swimming by. The tangle of lanes all lead to three interlocked squares lined with tavernas and bite-size bars, where evenings drift by as you drink shots of rakomelo (warm grappa with honey).

One of Japan‘s most talented chefs, Yoshihiro Narisawa presents Japanese ingredients in a style he calls “innovative Satoyama cuisine,” which highlights the country’s natural bounty. Narisawa works directly with purveyors to get the freshest seafood and produce. Bread is cooked on the table, there is soup made from soil (yes, literally dirt, along with burdock roots), and a forest-inspired dish that has a live audio feed from a forest in Japan. The exquisite meal is not gimmicky and involves a dizzying array of ingredients, and the wine-pairing option includes some very interesting, untraditional sakes, a great education in the spirit. Knowledgeable staff explain the provenance of each dish—it’s like an edible tour through Japan.

This national park is an ecological preserve with upland watersheds, mangrove forests, and estuarine and marine environments that support threatened and endangered species. The park also includes the Columbus Landing Site, a National Historic Landmark that is the only known place where members of a 1493 expedition led by Christopher Columbus (his second voyage) set foot on what is now United States territory. Columbus and his men met a tribe of Caribs here, so it was the first documented encounter between American Indians and Europeans.

The Kinnekulle area on the south bank of Lake Vänern is a paradise. Home to 18 nature reserves, the unique geology and chalky soils provides the perfect growing conditions for plants like ramps, ivy and various rare species like wild orchids. Kinnekulle is often referred to as “the flowering mountain.” In May, seeing the white ramps bloom thickly over the lush fields of Munkängarna nature reserve and smelling their subtle scent of garlic is something you just have to experience for yourself. A former chalk quarry at the edge of forest is a lovely picnic spot, and there are a number of fishing holes. There are also many medieval churches in the area, some of which date back to the 12th century.

The vibe in Waikiki is the most frenetic of all the spots in the islands, but there is an escape. The scene at the current iteration of the classic Hawaiian hangout, Duke’s, is a step back even by Oahu standards. Best approached via the beach to enhance the original feel and avoid the mall-like carnival from the street entrance, this is the kind of bar that welcomes sand on your flips. Slip in for happy hour and be prepared to jockey for a spot. Even with the crowd, the music, the food, the drinks are all designed draw you back to a simpler time when Duke was still riding the longboard. I’m partial to the beers and french fries, but will never refuse a fish taco. With a long relationship with the Kona Brewing brand, I opt for the Longboard larger or Fire Rock Pale ale. The umbrella drinks don’t disappoint, but neither do the gin and tonics. The local musical talent that ply the stage at Duke’s are traditional Hawaiian in style and like to keep the island theme front and center. There is a family vibe to the musical community, much like the rest of Hawaiian culture, and it’s not unusual to get a sibling or cousin to come up on stage and do some traditional Hawaiian dance or help out on a song or two. There was an 8 year old girl that got asked to come up on one of our visits and she blew the crowd away! The strip a Waikiki can be a bit daunting in terms of relaxation, but Duke’s remains my refuge from the madness. Aloha.

In 1946, Picasso worked from a studio in the Château Grimaldi of Antibes, creating 23 paintings and 44 illustrations that he gifted to the town. Later, 78 pieces that he designed for the Madoura pottery studios in Vallauris were added to the collection and the château became the world’s first Picasso museum. The nearby Archaeology Museum is housed in a historic fort and explores Antibes’s origin as the ancient Greek town Antipolis.

Like on French counterparts Martinique and St. Martin, Guadeloupean rhum agricole is distilled from 100 percent pure sugar cane juice rather than from molasses (and is known as “rhum” versus “rum”). A number of well-respected small rhum factories in Guadeloupe—including Boulogne, Damoiseau, and Bellevue—offer distillery tours year-round, and these are particularly interesting during the sugar cane harvest season between February and June. Domaine de Bellevue, in Marie-Galante, is a solid pick for a full educational experience. You’ll see the ancient sugar mill, learn about the eco-friendly distillery process, and taste various rhums (including one flavored with Ethiopian beans) as well as a traditional ti’ punch, Guadeloupe’s official cocktail. There’s on-site shopping as well in case you’d like to stock up for home.

Housed in a refurbished building on a four-acre private peninsula, this all-inclusive luxury resort is far more expensive than most hotels on Lake Titicaca, but it’s well worth the splurge. Not only are all of your meals, cocktails, and most excursions included, but the lodge invests deeply in the local community—it hires more than three-quarters of its staff from the surrounding area, sources as many ingredients as possible from regional farmers, and turns to nearby artisans for its textiles and other crafts. Additionally, the on-site restaurant is one of the best in the area. If you’d prefer a more private dining experience, take your meal on one of the hotel’s wraparound terraces, or order 24-hour room service.

All 18 rooms face the lake and feature heated floors (it can get chilly at night at 12,500 feet of elevation), a banquette overlooking the water, a free mini-bar, and deep bathtubs. King rooms are the most economical, but the two corner rooms—with their spacious layouts and panoramic views of the lake—are the most requested. For the best sunrise or sunset vistas, choose either the “Dawn” or “Dusk” rooms.

Xian’s art district is called Shuyuanmen, 书院门, and there are some local artists here that sell paper cut art. Paper cutting began as a major art form in Xi’an around the seventh century, which was the city’s heyday. People in China place cut paper on their windows and doors to celebrate various auspicious events. For a wedding, red paper cuttings are traditional and are required as decorations for the service. A big red paper character, 喜喜, (double happiness) is crazy-popular for newlyweds. The little stands on the street in Shuyuanmen are probably selling mass-produced paper cut art, so be sure to haggle. Don’t pay a lot unless you see the master at work.

Welcome to Laad Bazaar, tucked away on one of the four streets that lead from the Charminar. Also called Choodi Bazaar, the vibrant market features countless shops and stalls selling bridal wear, pearls, jewelry, and the famous Hyderabadi glass- and stone-studded bangles. These recognizable bangles are made from laad (“lacquer”), the material which gives the market its name. No cars or auto-rickshaws are allowed on the narrow street, and the crowds are limited to pedestrians, scooters, and bicycles.

Parque de Oueste is a shady park toward the north of the city. The park is known for its rose gardens, as well as being home to the Temple of Debod, a gift for the Egyptian state in 1968. The overlook of the park offers beautiful views of the Royal Palace and the larger Casa Del Campo. It’s an ideal spot to split a bottle of wine with friends and watch the sunset after a long day of exploring Madrid.

The Franciscan Basilica di Santa Croce, with its striped green-and-white marble facade, dates from about 1294. Inside are the tombs of many celebrated early Florentines, including Dante, Michelangelo and Machiavelli. Among the many art treasures are radiant frescoes by Giotto and his pupil Taddeo Gaddi, which decorate the Bardi and Peruzzi chapels, and the newly restored Cappella dei Pazzi, a Renaissance architectural masterpiece designed by Brunelleschi.