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Pearl was founded in 1881 as a traditional brewery. These days, however, the bustling complex is less about beer than its 15 restaurants, dozen-plus retailers, and numerous family-friendly events, including a twice-weekly farmers’ market. Start with lunch at La Gloria, chef Johnny Hernandez’s nod to interior Mexico, followed by dessert at Bakery Lorraine, where you’ll find an enticing rainbow of Parisian-style macarons. If you’re in the mood to shop, pick up a tailored guayabera from Dos Carolinas, or a piece of handcrafted jewelry from Ten Thousand Villages. Pearl Brewery is even home to Hotel Emma, a true gem in San Antonio’s boutique-lodging scene, in case you don’t want to leave.

The Casa Estudio Luis Barragán is a must for visitors to Mexico City interested in the works of Mexico’s most famous contemporary architect, Luis Barragán, famous for his colorful approach to modernism and his buildings that are as known for their garden settings as for their interiors. While that museum, located in his former house, is the most obvious introduction to his life and works, those who want to dive deeper will want to arrange visits to some of his other buildings.

The Casa Cuadra San Cristóbal dates from 1968 and was designed for the Egerstrom family. The centrality of gardens, plazas, and fountains to Barragán’s work is driven home here by the fact that the house itself is closed to the public. It’s still worth the effort to make the journey (of about 35 minutes to an hour by Uber, depending on traffic) to see the stables and gardens, and the exterior of the house. The walls in pink, mauve, and white, and the large pool at the center of the property create a space that is at once both restrained and exuberantly colorful. Reservations ([email protected]) are required and there is a charge of 300 pesos per person, with a minimum of five people. (You can visit with fewer than five people, but you’ll still need to pay 1500 pesos total, cash only.)

This restaurant feels like you stepped back in time - think Mexico in the 70s. The story goes - it all began in the VW van in Playa del Carmen. Tacombi used to sell tacos out of the van, and now he has a nice, cozy spot in Soho where the van is parked. It’s a garage with lights strung in the air. It just feels cool to be in. The design is great, but the food is even better. Virtually any tacos you order are wonderful. I also recommend the guacamole appetizer - yum! And don’t leave without ordering a drink.

Los Danzantes is a hip restaurant offering contemporary Mexican cuisine. It’s located on Alcalá street, in the same building that houses the Oro de Monte Alban jewelry store. It’s in a large partially covered patio space, with adobe walls and a koi pond on one side, and a bar made of recycled materials. Many of the items on the menu are made with traditional Mexican ingredients, but combined in new and interesting ways, and presented artfully. If you’re not feeling adventurous, there are also a number of pasta dishes to choose from. For dessert, the cascada de chocolate (fondant cake), served with vanilla ice cream will satisfy any chocolate cravings you may have—but order it in advance because it takes about 20 minutes to prepare.

An exploration of Tlaxcala can begin and end in the Plaza de la Constitución, the zocalo in the old town center. Within walking distance are the Plaza Xicohtencatl, often full of crafts and food stalls, the Ex-Convento Franciscano de la Asuncion (built in the 1530s and one of Mexico‘s earliest monasteries and cathedrals, boasting a visually spectacular interior within its stone walls), several intriguing museums, and the municipal market. Around the zocalo itself you’ll find a colonial-style arcade of restaurants, cafes, and shops, the government building with an interior courtyard painted with historic murals, the Hotel Posada San Francisco an appealingly intimate bar, and plenty of places to park yourself and kick back in the shade. Ninety-five percent of the tourists you’ll encounter will be Mexican.

Just inland from Ensenada, Baja California exists a wonderland of fine wine, haciendas and Provencal restaurants. There is an energy here that is worth dawning the bullet proof vest and heading a couple hours south of the Mexican boarder to check out the excitement and culinary innovation. In the Valle de Guadalupe wineries and restaurants are redefining where fine wine comes from and what Mexican cuisine can be. The Valle de Guadalupe sits in a valley that warms through the day and is cooled every evening by the onshore flow off the ocean, allowing perfect conditions for grape growing; which has been going on here for over a hundred years. Additionally, the valley is a source of fine olive oil, locally grown herbs and produce, local farms and seafood from the nearby ocean. The best way to experience this culinary movement is to stay at a winery like Adobe Guadalupe or Vinedos Malagon in the heart of the valley. These wineries offer more than just wine tasting and luxury, they offer activities, ranging from horseback riding to cooking classes, deep sea fishing or dirt biking. The best part of it all is you can still fill up on classic Mexican tacos and mariscos when the fine dining and wine becomes too much.

Chile en nogada is a poblano chile pepper, stuffed with peccadillo (shredded meat, aromatic diced dried fruit and spices), topped with a walnut-cream sauce and pomegranate seeds. This dish from Puebla is not often found on menus of Mexican restaurants in the U.S. It’s not even that common south of the border, except during the August-September season surrounding Mexican Independence Day. If you’re in downtown Tucson, however, you can try it at Penca. In a repurposed space with exposed brick and hip cocktails, this restaurant is also a worthy destination for brunch or late afternoon tacos. Choose from carnitas, fish, lengua, cabeza, nopales, carne asada, and more. The corn-tortillas are handmade right after you place your order. (The tortillas alone are almost worth the trip.) Mexico City is the inspiration. The food is fresh, and the scene is full of optimism: downtown Tucson is reinventing itself with a new streetcar for a live-work-play vibe. Taste and see how this desert city continues to evolve. (Penca has recently been named one of the best bars in the country. Start your meal here with a creative cocktail!)

Once the vacation home of the Italian Duchess Rosa de Ferrari, this exceptional estate was converted into a hotel in 2005. 2014 marked the arrival of a new owner and a new era for the property. Today, Hotel Esencia is an elegant small resort on one of the prettiest beaches on the Mayan Riviera. Surrounded by 50 acres of lush jungle and manicured, palm-fringed grounds, Esencia pairs the amenties and comforts of a larger hotel with the attentive care typical of a boutique property or B&B. Amenities include two swimming pools, a spa, and two restaurants. In the spacious rooms, lots of details stand out: iPod surround systems, well-stocked minifridges, 600-thread-count sheets, and walk-in closets.

For traditional Mexican handicrafts, Mercado Coral Negro is the easiest place to find all your wares. Here you can purchase jewelry, mayan relics, and unique creations from all over the region. The most beautiful items are the embroidered garments created from local cotton and dyed using traditional methods.

Baja Beans Roasting Company purchases beans from a family farm in Puebla and roasts them in a vintage coffee roaster in Todos Santos. Order a latte to sip in the café’s garden patio, or buy a bag of beans to bring home. Baja Beans Roasting Company, 52/(01) 612-167-3139. This appeared in the March/April 2012 issue.

Whether you wander by boat, bike, or tuk tuk (or, highly recommended, a combo of all three), Bangkok spills over with places both new and very old to explore. Along the way, modern-day wonders rub shoulders with traditional Thai culture. Hop from the floating market to a day cruise on the Chao Phraya River to a cocktail at one of the city’s innovative bars. Make meals of tastes from street food vendors and mix in some table service at some of the city’s most renowned restaurants. Overwhelmed by all the options? Stop for a Thai massage. Need souvenirs? The weekend market awaits.

Spain’s capital offers the best of food, art, architecture, and nightlife. For the best address in town, book a stay at AC Palacio del Retiro, set on the Parque del Retiro. For Old World splendor and a star-studded past, check in to the Gran Meliá Fénix. Foodies will want to score a room at Hotel Hesperia Madrid, home to one of Spain’s top restaurants, while design lovers will appreciate the details—old and new—at Urso Hotel & Spa in the hip Salesas neighborhood.

We’ve all heard about Sydney’s biggest cultural attractions like the Sydney Opera House and the Harbour Bridge, but how about a convict island turned event site or the local theater that launched the careers of Mel Gibson and Cate Blanchett? Sydney’s best cultural attractions are world-class and getting better every day. Contemporary favorites include Carriageworks and the Museum of Contemporary art, while the Art Gallery of New South Wales has one of Sydney’s best aboriginal art collections.

Cuatro Cienegas has got to be one of the coolest places on the planet earth! It is certainly not like any other place or ecosystem I have ever visited and I would have never imagined you could find paradise in the middle of the Chihuahuan desert. “Cuatro Cienegas” means “four marshes” in Spanish and at one point in history this place was a wetland. The pools, called pozas, are scattered throughout the desert around the town. Some of the pools are warm and some of them are freezing cold! They are a blast to swim and snorkel in! Cuatro Ciénegas is an official Mexican biological reserve because the ecosystem has unique fauna and flora that can’t be found any other place in the world! NASA stated that the biological reserve of Cuatro Cienegas could have strong links to discovering life on Mars, since the adaptability of bioforms in the region was unique in the world. How far out is that? Some refer to Cuatro Cienegas as the “Galapagos of Mexico”. Be sure you also check out the Gypsum Dunes that are also located here. This place is a geologist’s dream! I would recommend staying at Quinta Santa Cecilia during your visit, and although many of the pozas are mapped and marked you are better off hiring a local guide to take you to the best spots. Cecilia or the management of your hotel can assist here. The drug battles in this part of Mexico continue to dominate the press, but we did not feel unsafe during our visit here.

Located just footsteps from the hustle of Columbus Circle, Mandarin Oriental New York serves as the ultimate urban escape. More than 240 rooms and suites showcase stunning views of Central Park, the Hudson River, and the Manhattan skyline, while carrying their own perks within (Diptyque amenities, cherry wood furnishings, walk-in showers). The 14,500-square-foot spa feels like a true getaway in the heart of the city, with a tea lounge and a number of treatments ranging from Jet Lag Cure to Thai Foot Therapy.

The MO Lounge offers dramatic park views and an all-day menu with American cuisine centered on sustainable local ingredients. Come evening, MO Lounge’s hand-crafted cocktails paired with Central Park vistas are perfect for impressing out-of-towners.