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Hotels in Guadalajara tend to reflect their surroundings, whether they’re located in the trendy Lafayette neighborhood or the storied centro historico. Near the city’s expo center, there are also several stylish options for business travelers.

If you’re in the market for designer duds, Cancun and Playa del Carmen offer shopping centers full of upscale boutiques, familiar American brands, and Mexican department stores.

Life reflects art? The Reina Sofia museum in Madrid is home to Picasso’s famous Guernica, and many works by other Spanish artists, including Miro and Dali. A fabulous place to discover the art, artists, and ideas of the 20th century.

This silk mill turned cultural center on Lake Zurich’s left bank hosts over a hundred concerts, parties and festivals a year and is home to 60 art studios. It’s also a popular bar, especially come summer, when locals flock to the communal outdoor tables steps from the water’s edge (a favorite place to sit is in one of the handful of old-school ski lifts for prime views of the Alps). The setting is colorful and edgy—graffiti everywhere, plants shooting out from clawfoot bathtubs—a rarity so far from Kreis 4 and 5. Photo © Christian Beutler/Zürich Tourismus.

While the old city prides itself on shops that have been selling specific wares for centuries, new boutiques are popping up between the ancient ones. Alongside 200-year-old butchers and crumbling cafés, browse for stunning modern art, runway-style bridal gowns, and high-end children’s clothing.

Located right on the border of Georgia and Tennessee, Chattanooga makes for a great day trip or stop en route to Nashville. The city has Civil War history, a public art program, and great restaurants—with activities for every age.

Like most Italian cities, Milan has an amazing and very visible history that spans two millennia of art and architecture. But what really distinguishes it from other città is the ever-present testament to modernism and modern architecture—all accessible via the charming vintage trams.

The founder of White Wabbit, Taipei’s most influential indie record label and shop, KK Yeh finds inspiration in the city’s controversial art galleries, revolutionary teahouses, and red-light district temples.

Surrounded by Mayan ruins and one of the most luxurious tropical environments in the world, Cancun is rich with cultural and natural history. Its vibrancy attracts visitors year-round.

If you’re determined to see Florida’s iconic animals, you’ve come to the right place. Whether you visit the wildlife refuges, nature centers, or boardwalks, you’re likely to spot manatees, dolphins, sea turtles, alligators, and several birds.

Things move a little more slowly in Sacramento than in California’s other big cities. Local food and wine, an eclectic vibe, beautiful weather, and history as the state capital and center of the Gold Rush make Sacramento a fun yet laid-back place to explore.

Haidhausen, located just east of the city center, is one of the prettiest districts in Munich. It’s often referred to as the “French Quarter.” Streets here in Haidhausen have French names and the layout is similar to cities in France. It’s a great neighborhood for a self-guided tour on foot and to see how Müncheners (as Munich locals are called) live. You’ll find plenty of cafes serving up traditional Bavarian cakes!

The centerpiece of the city’s emerging Vulkan neighborhood, Oslo’s very first food hall is a culinary utopia. Let your nose guide you to one (or five!) of 27 eateries peddling everything from cupcakes to tapas to bento boxes. Can’t decide? Stop at the Torget stall and order the Taste of Mathallen menu to sample mind-altering dishes from the hall’s best restaurants. The communal wooden benches in the center of the hall encourage sharing, so you and your friends can divide and conquer. Finish your visit with a craft beer in the basement pub Smelteverket, which features Norway’s longest bar.

Founder’s Note: Betting on Africa

A multipurpose contemporary art center that opened in November 2011 in the Ottoman Bank building, Salt has a library with thousands of shelves of art publications—the most important, impressive collection in the city.—Sylvia Kouvali