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Located in the small river town of Hannibal, the Mark Twain Boyhood Home & Museum is actually a cluster of eight buildings that pay homage to one of America’s most celebrated authors. Visitors can tour Mark Twain’s Boyhood Home & Garden—a designated National Historic Landmark—to see where Samuel Langhorne Clemens grew up and the real adventures of Tom Sawyer took place, then pop into the Interpretive Center to view a timeline of his life and several interactive exhibits. Also worth checking out are the Huckleberry Finn House (where Tom Blankenship grew up), the Becky Thatcher House (featuring a museum dedicated to Laura Hawkins and childhood in the mid-1800s), the J.M. Clemens Justice of the Peace Office (where Twain’s father held court), and the Museum Gallery (home to 15 Norman Rockwell paintings and treasured Clemens family artifacts). Before heading out, be sure to pose for a family photo in front of the Tom & Huck Statue, which sits at the foot of Cardiff Hill.

For 20 years now, the Spring Mountain corridor north of the Las Vegas Strip has been a hotbed of hot pots—and every other Asian dish under the desert sun. When celebs such as Anthony Bourdain and Penn Jillette raved about the real-deal northern Thai cuisine at Lotus of Siam, chowhounds followed. Tell your friends you’re finally making the trip out to the strip mall and they’ll tell you to avoid the items you can order from the takeout joint at home: no pad thai, no chicken satay. They’re right. Dive into the last page of the menu, the one about dishes from Northern Thailand, then entrust your tastebuds to the award-winning hands of Chef Saipin Chutima and try her larb or the jackfruit curry, anything with ground pork sausage, the khao soi (egg noodles and meat in a coconut curry sauce), the nam prik ong (a chunky mix of pork, tomato, and red chili, served with lettuce and raw vegetables), or the whole fish with chilis. The food is spicy, yes, and the afterburn is serious, but the depth of flavor is sublime enough to make you weep with regret the next time you have to call your local takeout place for delivery.

The Eastern Market, now a National Historic Landmark, opened in 1873 to serve the Capitol Hill neighborhood (an 1805 version, located down by the Navy Yard, was a casualty of the War of 1812). The brick market hall, packed with butchers, bakers, vegetable markets, cheese vendors, flower kiosks, and a lunch counter, is bright and charming. Under the shed roof outside, additional local produce is displayed and sold. On weekends, booths selling vintage goods and handmade jewelry, housewares, and clothing do a brisk business down the center of 7th Street. Crowds spill out of the cafés, taco joints, and bagel shops occupying the first floors of the row houses along the block, adding to the lively mix at the market.

Completed in 1916, this Italian-inspired villa on Biscayne Bay was the home of the early 20th-century industrialist James Deering and is now a National Historic Landmark. The house was modeled after historic villas and country estates in the Veneto region of northern Italy. The heart and main living area of the house is the Courtyard, which was originally open to the sky. Diego Suarez, who had worked in Florence, designed the gorgous formal gardens with classic Italianate flair, but modified for the heat and humidity of southern Florida. Thousands of varieties of orchids flourish in the greenhouse, while subtropical trees, palms, and low hedges highlight the lines of the gardens’ layout.

Taking just the ‘right’ wrong turn on a visit to Pike Place Market can land you in Post Alley, where spearmint, wild cherry, and tropical punch bubble gum drizzles down the window panes and grape, peppermint, and lemon ice gum-cicles form from sills. It may be one of the lesser-known Seattle tourist attractions, but it certainly makes a big impression with plenty of chaotic color on a rainy day. And if you’re a gum chewer, be prepared to stick a drop of your own favorite flavor to leave a colorful mark on the city.

With headquarters in Portland, Oregon, the Ace Hotel brings a dose of Pacific Northwest cool to the Flatiron District of Manhattan. Located in a turn-of-the-century building, the Ace has become a hub for stylish visitors and freelancing New Yorkers—locals often set up shop in the hip lobby to work and sip Stumptown coffee. The aesthetic is laid-back yet creative, with fun local art, free Wi-Fi, and quirky touches like tabletops made from discarded Hubble telescope lenses. The Ace is unpretentious and inviting, with a social and interactive lobby and two destination restaurants. Rooms range from small bunk rooms to spacious loft suites—offering a match for a variety of price points.

The natives that guide you through Canyon De Chelly are very passionate about their historical heritage: the battles that their people have survived, the ceremonies they live by, and the dwellings that they carved out of the massive cliff sides. The Navajo people had to hide in the mountains, and for extended times they weren’t even able to come down for food or water. The Human Chain is the story of how they created a chain by climbing down each other in the night to bring up baskets of water while their enemy slept. Many survived because of that daring task.

Over the past two centuries, the covered market at Borough, not far from London Bridge, has become one of the country’s most famous foodie spots. From Wednesday to Saturday each week hundreds of traders gather to sell homemade breads, hand-reared pork, artisan chocolate and all manner of ingredients—plus excellent coffee, fresh juices and organic wine. Plentiful samples add to the convivial vibe, and restaurants around the market’s edge provide additional sustenance for longer stops.

A three-day safari in Kruger National Park is a must for anyone visiting South Africa. Entering the gates is like Jurassic Park and you feel transported back in time to the creation of Earth where the wild animals, especially the elephants, are dinosaurs filled with ancient knowledge of the land’s beginning. Although you may not see anything like the infamous “Battle at Kruger” YouTube video, you will certainly witness some interesting animal behavior like hippos bathing, monkeys mating, giraffes snacking or even two elephants flirting in the brush.

I’m not sure at what age humans develop the skill to stand still and appreciate scenery, but based on a scientific survey of kids who live in my house, it’s not age seven. (On a trip to the Canadian Rockies, as my wife and I snapped photos of the relentlessly picturesque mountains, my son, Luke, investigated how quickly he could break his toy helicopter.) Luke expects Mother Nature to be his playmate. At Bandelier National Monument, about an hour’s drive from Santa Fe, New Mexico, she is. The visitor center offers kids a booklet of activities that, when completed, earn them a Junior Ranger patch. (You could call it a bribe. We prefer the term incentive.) The scavenger hunt sent us off on the Main Loop Trail in search of birds, trees, and bugs, as well as the feature that sets Bandelier apart and makes it perfect for kids: cave dwellings. Ladders of salvaged wood lead to rooms that the Pueblo people carved out of the cliffs here over 800 years ago. “I don’t want to go up, Daddy,” Luke said. “It’s too steep.” “You’ve got this, buddy,” I said. “Just take it slow.” There were no lines of impatient parents pushing their children to race up the ladder. (We saw no more than 20 people on the trail.) Luke could climb the rungs at his own pace. He paused in triumph at the top, then set off to wander the caves. While Mom and Dad squatted—“Watch out for your bald head, Daddy”—Luke could explore without even hunching. After about 45 minutes, we were walking back toward the visitor center. We crossed a nearly dry creek by hopping hand in hand from one downed log to another and were back in time for lunch, before hunger, fatigue, or boredom could set in. It was a parent’s—and child’s—dream hike. This appeared in the August/September 2014 issue.

Two architectural wonders helped put Dubai on the map: the Burj Al Arab hotel, which resembles the sail of a ship out on the gulf waters, and the Palm Jumeirah, a residential development on a manmade archipelago that fans out in the shape of a huge palm tree. But in 2010, the sleek Burj Khalifa stole their thunder. Now the world’s tallest structure, the tower soars 830 meters (2,722 feet) into the sky. Visitors can zoom by elevator up to the 124th floor to experience incredible views and explore interactive displays on Dubai’s history and the tale behind the building of this futuristic marvel. Another observation deck is even higher, on the 148th floor.

The Centre Pompidou, France‘s national museum of modern art, led the way for steel-and-glass buildings in the 1970s. Now the museum leads the way in modern art with its extraordinary collection, currently the world’s second largest. Masterpieces include Pablo Picasso’s Parade and—one of my favorites—Tamara de Lempicka’s Young Girl in Green. Go for the museum, but check out the public library and the view of Paris that becomes more and more impressive as the museum’s escalators rise from floor to floor. Spot the Eiffel Tower and Sacré-Coeur (and perhaps a street entertainer or two with a gawking audience of kids) from the sprawling roof terrace.

Istanbul’s Spice Bazaar may be a global tourist trap, but isn’t nearly as rage-inducing as the squawking group tours inside the Grand Bazaar. Here, a remnant of authenticity lives on in this 17th century building, created by commission for Sultana Turhan Hatice. Visually-arresting piles of spices and Turkish delight, and rows of pushy men, make for a wild afternoon of souvenir shopping and colorful conversation. Inside the Ucuzcular stall the sellers are friendly and happy to let you browse. A bag of “love tea” ensures romance in a pot. In that vein, on my way through the bazaar, a man trotted up to me and said, “Excuse me. I think you dropped something...” I looked puzzled. He smiled and theatrically clutched his chest, "...my heart.” He probably does that for all the Westerners, but I pretended it was as real as the magic in the spices.

The central hub of downtown Amsterdam is Dam Square, and it’s been at the heart of the city’s history since the 13th century. Today, the open-air public space is ringed by shops and restaurants and packed with people, including street performers and tourists en route to nearby attractions like the Royal Palace, the National Monument, and the Nieuwe Kerk (New Church), where you can catch a horse-drawn-carriage tour of the city.

This upscale restaurant offers a glimpse into Kerala’s unique history along with its flavorful meals. Enter a stone archway to find yourself in a courtyard of a restored 18th-century mansion that was first built as a traditional, two-courtyard ettukettu house for the King’s consorts, then later embellished with European architectural flourishes. Choose a seat in the antique-furnished (and air-conditioned) interior, under one of the courtyard’s peaked stone-roof gazebos, or in the garden, surrounded by statues and fountains; all options take on a decidedly romantic feel at dinner when illuminated by candlelight. The menu includes both modern version of regional classics and dishes that highlight the flavors of areas once linked to Kerala by the Spice Route, including Morocco, Italy, and other parts of India. So you’ll find everything from Syrian sampler platters, crab curry, pasta, and fish sautéed with onions and black pepper, and desserts featuring caramel, chocolate, and local coffee—all presented with heritage style.