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Active from the 13th to 15th centuries and considered an influence on the pre-Renaissance movement, the Sienese School of painting is identifiable by its themes—always religious, and usually with a focus on Biblical miracles—and its signature style, a dreamy mix of Roman, Gothic, and Byzantine influences that often feature dazzling gold backgrounds. Opened in 1932, this museum boasts one of the world’s largest collections of Sienese School works, as well as a number of Renaissance and late-medieval pieces from Italian artists. Wander through the impressive building—a combination of two 14th- and 15th-century noblemen’s palazzi—to find works like Duccio’s Madonna and Child, Michelino da Besozzo’s Mystical Marriage of Saint Catherine (celebrating the “calling” of Siena’s native daughter), and Bartolo di Fredi’s expansive Adoration of the Magi. Paired with a visit to Florence’s Uffizi, coming here offers insight into the differences—and longtime rivalry—between the two cities.

On a weekend morning, hop on Metro Line 10 to the Panjiayuan station and take exit B. Just down the road is the sprawling Panjiayuan Market, where hundreds of vendors sell their wares. It’s essential to bring cash, patience, and a willingness to bargain. While there aren’t authentic antiques here, you will find loads of curios from the 1950s onward, including a superb selection of colorful propaganda posters at a fraction of what they sell for in central Beijing shops, as well as lacquerware, teapots and cups, jewelry, chopsticks, and textiles. Larger items, like traditional carved-wood furniture and substantial framed paintings, can easily be stowed in one of the taxis that wait patiently near the entrance for happy shoppers.

While Dallas has never lacked for luxury shopping options—throw a Jimmy Choo stiletto and you’ll hit a designer boutique or upscale department store here—4510’s concept-store format, featuring a well-curated selection of fashion and design pieces from big, emerging, and independent designers, made waves when it first opened in 2000. Since then, the brand has grown to include other outposts in Texas and California, as well as this 37,000-square-foot, four-story flagship in downtown. (The original McKinney Avenue location has been transformed into a home-focused store, and there’s another location in Highland Park Village, too.) Topped by a chic restaurant and filled throughout with artwork, the store continues to feature women’s and men’s fashions, home decor and furnishings, jewelry, and beauty products by labels known for creativity and craftsmanship. The lineup varies, but you can be sure the selection will be thoughtful and fun, and that many of the pieces will be one-of-a-kind or newly available to retail—ensuring that you’ll leave with something special.

It’s impossible to ignore the hulking 1950s architecture of the Tate Modern, slap-bang in the middle of the most-walked part of the South Bank. A visionary refurb of this former power station has resulted in an artistic behemoth with multiple gallery spaces (containing both free exhibitions and ticketed exhibitions), including the fantastic Turbine Hall for oversize installations. Outside, the Millennium Bridge leads over the Thames to the City and the great domed St. Paul’s Cathedral.

Taking just the ‘right’ wrong turn on a visit to Pike Place Market can land you in Post Alley, where spearmint, wild cherry, and tropical punch bubble gum drizzles down the window panes and grape, peppermint, and lemon ice gum-cicles form from sills. It may be one of the lesser-known Seattle tourist attractions, but it certainly makes a big impression with plenty of chaotic color on a rainy day. And if you’re a gum chewer, be prepared to stick a drop of your own favorite flavor to leave a colorful mark on the city.

The Basilica San Marco is Venice‘s crown jewel. Situated at the eastern end of Piazza San Marco, the cathedral was built around 1078 on the site of an earlier house of worship. It is famously the home of the remains of the apostle Mark, which were said to have been smuggled from the Holy Land by Crusaders in a barrel of pork. The basilica is not just a wonder from the outside; its glittering gold mosaics make it one of the most breathtaking examples of Byzantine design in the West.

Belize’s liveliest time of the year comes in September, when the entire country celebrates independence for three entire weeks leading up to Sept. 21. The major towns and cities host various events, and a countrywide calendar is published on Sept. 1, allowing you to follow along with the fun wherever you might find yourself in Belize. The most popular events are a steel pan concert called Pan Yaad, held in Belize City, and two full-blown carnival parades. Belize City Carnival, with soca and Caribbean music blaring, is held in mid-September, while Orange Walk Carnival takes place on Independence Day and celebrates Mestizo heritage. Take advantage of low-season fares to get a unique culture-filled experience in Belize in September.

The natives that guide you through Canyon De Chelly are very passionate about their historical heritage: the battles that their people have survived, the ceremonies they live by, and the dwellings that they carved out of the massive cliff sides. The Navajo people had to hide in the mountains, and for extended times they weren’t even able to come down for food or water. The Human Chain is the story of how they created a chain by climbing down each other in the night to bring up baskets of water while their enemy slept. Many survived because of that daring task.

Italy’s beloved region of Tuscany brings to mind bucolic vineyards, rolling hills, and roads lined with towering cypress trees. But there’s plenty else to delight and even surprise travelers. Consider the quaint town of Punta Ala: located along the southern Tuscan coast, it’s under the radar of most travelers, yet the go-to summer escape of generations of Romans and Florentines.

Punta Ala strikes a balance between relaxation and understated elegance that encourages lingering, and the same goes for its premier place to stay: Baglioni Hotel Cala del Porto. Set against the backdrop of the Mediterranean Sea and with two adjacent beach clubs (La Vela and Alleluja), the hotel’s 38 airy rooms offer views of the gardens and marina. In the heart of Maremma, Hotel Cala del Porto is perfectly located for day boating trips out to the island of Elba, wine tasting at notable Tuscan wineries, and some of the best golfing in Italy. The regional park Bandite di Scarlino beckons with hiking trails ideal for early morning risers.

This hotel is on our list of The 10 Best Hotels in Canada.

First opened for business in 1912, the iconic Ritz-Carlton Montreal—known as “the grande dame of Sherbrooke Street"—began a $200 million facelift in 2008, opening its doors again in 2012. Quebec’s most luxurious and historic hotel could tell endless celebrity secrets but is, of course, far too discreet to utter a word. It’s no secret, though, that Elizabeth Taylor married Richard Burton here, that the Rolling Stones rented the entire sixth floor in 1972, and that a who’s who of world leaders, movie stars, and royalty are still regular guests. Situated in the downtown culture and shopping hub that is the Golden Square Mile, the hotel oozes money-is-no-object luxury from every pore: from the ornate duck pond and immaculately manicured garden and terrace to the 100-year-old chandeliers, the sweeping staircases, and the belle époque golden glow of the lobby and palm court. Rooms have a white-and-gray minimalist palette with splashes of signature purple. Antiques and original features blend with ultra high-tech design such as Japanese Toto toilets in all bathrooms, heated floors, and motion-sensor lighting.

A visit to the incredible 365-island archipelago (also called the San Blas Islands) within the communal lands of the Guna Yala indigenous nation provides some extraordinary seaside experiences. The islands making up the outer archipelago are unspoiled and feature gorgeous white-sand beaches, turquoise seas, and a one-of-a-kind encounter with Guna culture. Visitors lodge in natural-material huts (cane walls and interwoven palm-frond roofs) or—if you’re in the mood—sleep under the stars in palm-strung hammocks. Local women sport colorful dress made in the style known as mola, a traditional Gula artisanal weaving technique. A highway was built several years back that lets you travel from Panama City to Puerto de Cartí in as few as two hours.

Located just off Main Street, the Washington School House Hotel eschews Park City’s typical rustic style for a pared-down, flea-market–chic aesthetic. Before being reimagined as a design-oriented inn in 2011, the 1889 building served as a schoolhouse for miners’ children and a dancehall for the local outpost of Veterans of Foreign Wars. Today, the interior is anything but traditional, from the whitewashed living room with 16-foot ceilings to the antique mirror and the white, lacquered antler chandelier. Outside, a heated pool sits on the hillside surrounded by aspens and boulders. There’s also a fire pit, fashioned from a steel Olympic torch from the 2002 Winter Games.

Each of the guestrooms and suites is unique, though all feature reclaimed wood floors, crystal chandeliers, and tall windows. An artful collection of European antiques and vintage paintings adds a bohemian vibe, while white marble bathrooms offer heated floors, walk-in showers, clawfoot tubs, and period fixtures. Guests can also look forward to plush hooded robes and top-notch toiletries from Molton Brown.

Swift streams and waterfalls continue to carve these vertiginous and rugged valleys as they pour into the sea. One of the most stunning wilderness areas on earth, it also contains ancient Hawaiian ruins of graves, temples, house platforms, and terraced fields. The fear factor increases past the initial two-mile path to Hanakāpīʻai Beach (best visited in summertime, as winter swells tend to wash it away). Only experienced hikers in good condition and with proper gear should venture further along the famous 11-mile Kalalau Trail. Check for path and park closures before making plans and don’t forget the $20/night permit to crash at a campsite. However long you trek, stay on the main path and pack out what you brought in.

Arthur Guinness, the forefather of the world-renowned family, founded the brewery on this inner city spot in 1759. It’s the city’s most visited tourist attraction, telling both the history and processes that have gone into making Ireland‘s most famous export. At the end of the tour, visitors are treated to a pint of the famed black stuff at the top-floor Gravity Bar with its panoramic views of the city’s skyline.

The main branch of the New York Public Library is one of the country’s grandest Beaux Arts buildings, a temple to learning on Fifth Avenue between 40th and 42nd streets. At the end of the 19th century, John Bigelow, who oversaw the Tilden Trust, decided that as New York was becoming a global financial capital, it required a grand public library. When the Astor and Lenox libraries faced financial difficulties, he convinced them to merge and, with the Tilden Trust, underwrite the library that now stands next to Bryant Park. The firm of Carrère and Hastings was entrusted with the design, and construction began in 1902 on the building that would be the largest marble structure built up to that time in the United States. The elegant main reading room with its soaring carved-wood ceilings is the highlight of its interiors. The library hosts temporary exhibitions related to literary and cultural topics that draw on its extensive collection of books and other printed materials. The two beloved lions in Tennessee marble—Patience and Fortitude—have stood at the entrance to the library since it opened in 1911 and were created by sculptor Edward Clark Potter.