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Considered by some as a Milan institution, Cantine Isole is a small wine bar/enoteca with a lot of history and great atmosphere. It’s located in the Chinatown neighborhood, near Garibaldi station and the Isola neighborhood. Expect a lot of character.

Prague’s National Gallery is located in eight distinctive buildings and palaces throughout the city, each one dedicated to particular periods, spanning from medieval times to the 21st century. The collection was begun in 1796 by a group of nobles and intellections and has grown to include 400,000 works of art today. In Veletrzni Palace, you’ll find Czech and European art from the 19th century to today, includin a comprehensive collection of works by František Kupka, Czech cubism, plus works by Rodin, Gaugin, Van Gogh, Lichtenstein, and Picasso. The art of Asia and the ancient Mediterranean is exhibited at the Kinsky Palace while the Sternberg Palace showcases European art from antiquity through the Baroque period.

If eating huge plates of pork, deciphering local slang, and snowshoeing through the woods of Québec can’t bring two siblings together, what can?

The gallery, boutique, and tearooms of Morocco’s most famous living artist, Hassan Hajjaj, is an essential stop for any art lovers staying in the city. Tucked away down a narrow alley behind the Rahba Lakdima (otherwise known as the Place des Épices), it’s like stumbling into a jewel box filled with pop-art treasures. Hajjaj made a name for himself with a series of photographs titled Kech Angels, which depicted local girls on mopeds dressed in eye-popping robes. The collection has been exhibited all over the world in such illustrious venues as the Victoria and Albert Museum in London and the Institut des Cultures d’Islam in Paris, but nowhere beats enjoying the work on home turf. While you’re there, treat yourself to his iconic recycled home and fashion pieces, such as a sardine-can lantern, a pair of babouches (Moroccan slippers) cut from a flour sack, or a stool from an oil drum. And if you hang around for a pot of mint tea in the courtyard, you might even meet the man himself.

On a quiet residential street one block from the popular vintage shops, bars, and restaurants of Milwaukee Avenue, the Wicker Park Inn is one of the best values in Chicago, attracting an eclectic clientele of older couples, families who book the whole place for weddings and other special occasions, and young travelers eager to live like a local amid the vibrant culture of the Wicker Park and Bucktown neighborhoods.

There’s more to the Botanical Gardens in Denver than just the pretty face of its landscaped grounds and beautiful flowers. It’s also a world-class research center with a mission to connect people with plants (especially the plants endemic to the Rocky Mountains) and to encourage understanding of the ecosystems in which they thrive. The 23-acre location on York Street has a variety of gardens (many based on typically western climates like mountains and plains), popular exhibits, and a shop; it additionally hosts a summer concert series and nighttime events. The institution’s second main location, at Chatfield Farms on the southwest edge of greater Denver, focuses on native flora and agriculture; there’s a working farm on its 700 acres. Both spots offer extensive educational opportunities as well as incredible events like York Street’s Blossoms of Light holiday show.

Barranco, one of the city’s most beautiful neighborhoods, awash in character, is known for an artsy vibe and gorgeous colonial buildings. Cross the Puente de los Suspiros (Spanish for “Bridge of Sighs”) and follow the Bajada de los Baños to the seaside. Explore the side streets and duck into cute cafés and art venues, including the Museum of Contemporary Art (MAC). The gallery-shop Dédalo, in particular, is ideal for combining coffee, snacking, shopping, and art viewing. Visiting another Barranco landmark, the belle epoque Hotel B, provides a quick trip back to a time of elegant architecture. Splurge for a smart cocktail on the rooftop bar to linger a little longer.

It’s always been about affordable vintage goods at this Wicker Park boutique, which sells contemporary dresses and tops from Amuse, men’s hats from Brixton, denim from skinny-jean pros Just USA, rompers from Los Angeles–based En Crème, and handcrafted leather boots from Red Wing. The popular shop’s homewares and apothecary section is arguably the best place to pick up gifts your friends will love, from grooming and shaving goods to candles, perfumes, and barware like flasks and cocktail shakers.

Old school ice cream parlor and soda shop with homemade candy and ice cream since 1921 in the same location in Bucktown. I wish the little jukeboxes on the tables worked but clearly it’s not hampering their business as there’s a line out the door every day, especially in the summer. Margie’s is a small place but perfect for an afternoon sundae dripping with hot fudge and maybe a dozen chocolate dipped cherries to go.

Like most good thrift stores, the Brown Elephant is hit or miss. Sometimes you can find great books, T-shirts, and super-cheap vinyl—other times, nothing appeals, and you just wander around until your feet hurt. This shop is well organized, and most of the home goods are reasonably priced. All of the proceeds go to benefit the Howard Brown Health Center, a great LGBT charity; if you’re waffling on spending a couple extra bucks, just go for it and know that your money is going to help someone who needs it. (The Brown Elephant has three outlets: this one in Lakeview, one in Andersonville, and one in Oak Park.)

Adam and Skye Rust admit that they have a thing for taxidermy. And bones. And teeth. Adam has even made an animated sculpture where taxidermied mice circle and dance à la “Three Blind Mice.” They travel the globe to find the strangest and most visually impactful specimens to fill the motionless zoo and touch-friendly museum that is Woolly Mammoth Antiques & Oddities. Brussel Sprouts, the real two-headed calf (from Brussels); a ceremonial Odd Fellows skeleton; vintage medical tools; and old apothecary bottles all share space in this retail wonderarium. Not everything in Woolly Mammoth is a curiosity, but if it’s the unusual you’re seeking to buy, you’re bound to find it here.

Chef Pedro de Artagão went from fresh-faced promoter to celebrity chef at Irajá, where instead of trying to take things more haute, he gathered traditional—maybe even disdained—Brazilian ingredients and transformed them into something spectacular. The restaurant’s mansion setting requires guests to squeeze past the kitchen to the dining room, on a high-ceilinged loggia, framed by a vertical garden. Locals marvel at what Artagão does with once-lowly cassava, now stylishly presented as high-toned aipim (whole fried), farofa (fried meal), mash, or tapioca. Regulars and out-of-towners alike enjoy sampling ingredients from the Amazon, such as tucupi (manioc juice), jambu (a Brazilian guava), and tacacá (a spicy seafood, pepper, and jambu stew).

What happens in the Museo del Whisky stays in the Museo del Whisky. And in this institution of Donosti, you never know what will happen. With a wild selection of whiskeys (as the name suggests) and an equally impressive gamut of cocktails, Museo de Whisky is full of surprises. Then there are the characters that visit this spot on a regular basis. The bottom floor is a piano bar with no holds barred.

The Ottoman Bank Museum is in the basement of SALT Galata, an arts center located in the former Ottoman Bank. It’s a destination that will appeal mostly to those interested in the history of the Ottoman Empire in its decline at the end of the 19th century. But doesn’t everyone find the late Ottoman period fascinating? The struggles that characterized the era, with a country torn between its Ottoman past and a desire to both modernize and Westernize, played out at the bank. The institution that would become the state bank of the Ottoman Empire was founded in 1856 as a joint venture of British and French banks and the Ottoman government and was managed by a committee of British and French financiers until it was effectively dissolved during World War I. The museum includes many surprisingly engaging displays and documents tracing the bank’s history—its commercial ventures, demographic information on investors and employees, charts detailing the economic turmoil of the period. Architectural plans of the headquarters illustrate its unusual design that featured a neo-classical entrance facing the European quarter and an Ottoman-inspired rear elevation, facing Istanbul’s Old City across the Golden Horn. Deposit slips, photos of employees, and old bank notes in the original vault are on display in almost exhausting, encyclopedic comprehensiveness. If your interest wanes, you don’t need to feel any pressure to linger—entrance is free.

You’ve probably had the sauce, but did you know that there are three different places in Illinois where you can actually go and eat at a Sweet Baby Ray’s restaurant? With locations in Wood Dale, Elk Grove Village and Chicago, there’s no excuse. Falling under the label of ‘authentic urban Chicago style barbecue,’ Ray’s creative menu has a distinctive southern twang to it that everyone loves. Known for their ribs, chicken, pork, and awesome sandwiches, Ray’s also has a host of other craft choices. Spruce up your meal with one of the seven homemade sides, try the gumbo, or get your greens by adding a freshly made salad. And if you feel the need to take something home with you, there is a full selection of barbecue sauces that you can purchase for your very own culinary adventures back at the house.