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Most people know the Lou Ruvo Brain Health Center by its appearance—the nonlinear building was designed by Frank Gehry and bears the architect’s signature curves and twists. Inside, however, medical professionals perform incredible feats daily. The facility treats patients with degenerative brain diseases such as Alzheimer’s, Parkinson’s, and Huntington’s. Because the center is an active medical facility, access to the public is limited, but architecture fans are welcome to swing by, marvel at the undulating walls, and wonder how Gehry does what he does with metal.

Buda Bar, on the other side of the Havana tunnel in Cabaña, is a meditation center by day and a bumping party by night. Go after 10PM from Friday to Sunday to hear anything but reggaeton, play domino, or get your future told by an Osho card reader underneath the trees. Ask a young local for directions, as the spot is somewhat secret!

Montes + Mugica is a furniture studio and clothing store that devotes itself to good, clean taste. It’s been in the family for generations, but each generation has brought a new style to the shop. The young brothers José and Javier bring a distinct affinity for all things Nordic, resulting in a gorgeous, hip aesthetic and real treasures for sale. Don’t miss their monthly pop up market in their other building, Espacio La Central.

Nestled in a corner of shops off the well-heeled boulevard de la Madeleine, the shop approaches many of their 50 some mustard varieties like beer, offering them fresh and on tap. Flavors range from the ultra classic (course ground à l’ancienne, tarragon, white wine, honey) to the rather unique (black olive, mushroom, cognac), many of which are unavailable outside Paris and Dijon. Aside from being a fantastic spot to pick up gifts, the shop is a beautifully potent homage to Antoine Maille’s original vision and the country’s favorite condiment. No need to travel to Dijon for a taste of Maille, the legendary mustard producer (though I recommend it). Just add their Paris boutique to your travel itinerary!

One of the city’s top restaurants, Cicciolina offers Italian-style dishes with a Peruvian flair, such as quinoa-encrusted prawns and osso buco with pumpkin ravioli topped by local cheese and a touch of Andean mint. There’s plenty to choose from, including seafood, duck, beef, alpaca, chicken, and even a few vegetarian dishes, as well as perfectly done handmade pasta. You can pick from either the tapas or the full-restaurant menu in the bar area, but not the other way around, so you may want to go twice, as the tapas are fabulous, too. A great wine list and yummy desserts finish out options in a small, lovely venue. Reservations are a must.

The lines are long (expect to wait at least an hour) at this young barbecue joint tucked inside the Dallas Farmers’ Market—but the tender, perfectly smoked meats are worth the wait says Daniel Vaugh, barbecue editor of Texas Monthly. “They have incredible brisket and giant beef ribs,” he says. Watch for a brick-and-mortar outpost slated to open this spring—menu standbys like bacon-and-chile-flecked mac and the “trough” meat-sampler, pictured here, are sure to make an appearance.

When you hear the phrase, “summer in southern Arizona,” naturally your thoughts will tend toward heat and sunshine. Most wouldn’t think of mounds of fresh produce at a farmers’ market in the desert city of Tucson. But the arrival of the monsoon coincides with nature’s edible bounty, even here in the desert. The nearby Santa Cruz valley is actually one of the oldest continually-farmed regions in North America, with agriculture dating back four thousand years! Heirloom beans, squash, chiles, and tomatoes are still grown. The nearby higher elevation lands near Willcox are known for their orchards and even a few vineyards. Mesquite flour is made into cookies and tortillas. Prickly pear cactus is made into jams and frozen treats. All this is available throughout the week at various farmers’ markets around Tucson. The biggest one is on Sunday morning in the neo-colonial courtyards of St. Philip’s Plaza. And, if you’re curious, you’ll get language and cooking lessons, too. On a recent Sunday morning, my wife and I asked what some curious looking greens were. The answer? Purslane, or “verdolagas” in Spanish. They grow like weeds once the monsoon rains begin, and they contain more omega-3 fatty acids (think fish oil) than any other leafy plant. In a salad, or sautéed or stewed, they’re great. Who knew? Farmers’ markets are always a great place to get a vibe for a city—a cross section of people and produce. And, even in the desert, it is possible to shop and eat local.

For 20 years now, the Spring Mountain corridor north of the Las Vegas Strip has been a hotbed of hot pots—and every other Asian dish under the desert sun. When celebs such as Anthony Bourdain and Penn Jillette raved about the real-deal northern Thai cuisine at Lotus of Siam, chowhounds followed. Tell your friends you’re finally making the trip out to the strip mall and they’ll tell you to avoid the items you can order from the takeout joint at home: no pad thai, no chicken satay. They’re right. Dive into the last page of the menu, the one about dishes from Northern Thailand, then entrust your tastebuds to the award-winning hands of Chef Saipin Chutima and try her larb or the jackfruit curry, anything with ground pork sausage, the khao soi (egg noodles and meat in a coconut curry sauce), the nam prik ong (a chunky mix of pork, tomato, and red chili, served with lettuce and raw vegetables), or the whole fish with chilis. The food is spicy, yes, and the afterburn is serious, but the depth of flavor is sublime enough to make you weep with regret the next time you have to call your local takeout place for delivery.

Surprisingly enough, you can round the point at Point Dume and discover your own hidden nooks to spend the day. With cliffs at your back and a private beach with decent size waves in front of you, it’s not a bad place for a picnic.

Art isn’t the first thing that comes to mind when you think of Vegas unless you’re familiar with the term kitsch. However, Sin City has always looked to please almost every palate and many impressive art exhibitions and theatre are proving to be a worthy alternative to the neon lights of the slots. You may head to old Vegas for a cheap dinner and a show but have you ever thought of dinner and a Picasso? At Picasso in the Bellagio Hotel & Casino, you can dine beneath the original paintings by Picasso himself. It’ll certainly cost you at Julian Serrano’s restaurant and you may even feel as though you end up paying for one of the masterpieces upon the wall but the food and service are memorable. Try to get a table near the windows or outside on the patio for a view of the fountains. Can’t afford an entire meal but love Picasso? Head to the bar for a drink.

San Juan Cemetery lies on the coast adjacent to El Morro (San Juan’s beloved fort) and nestled in the district La Perla, a rougher part of town. Its statues and tombs make it as beautiful as a New Orleans cemetery. Exiting El Morro, head down the grassy field to your left to catch this flustering overhead view. On this day, a powerful storm was rolling in, casting everything in gray.

A colorful working-class neighborhood near downtown that had fallen on hard times, Woodstock has been revitalized with a mix of galleries, artists’ studios, boutiques, and restaurants. Much of the area’s original vibe remains, however, thanks to the long rows of colonnaded shops that edge Albert and Victoria roads. Among the nearby storefronts that are open throughout the week are Espresso Lab Microroasters and Luke Dale-Roberts’s award-winning restaurant, the Test Kitchen. Continuing down Albert Road, you’ll find spots like the Woodstock Co-op and the very trendy Woodstock Exchange, with a great array of places to eat and stores selling local goods. At the end of Albert Road, there’s a concentration of galleries, including the Stevenson, Goodman, and SMAC. On Saturdays, Woodstock draws crowds to the Neighbourgoods Market, a prepared foods extravaganza in the Old Biscuit Mill.

A UNESCO World Heritage site, this hotel was the home of Hispaniola’s first governor, Nicolás de Ovando, and one of the first colonial structures built at the top of cobbled Calle Las Damas (the first paved street in the Americas). Built in 1502 and connected in 1974 during a reconstruction ordered by then President Joaquín Balaguer, the three stone buildings retain their original coffered ceilings, massive arches, tile floors, and brick and stone walls. In addition to 92 rooms and suites, including a dozen Imperial Club rooms overlooking the Ozama River and Don Diego Harbor (Room 4015 has a particularly stunning view and gorgeous bathroom), you’ll find a lovely reading nook, gourmet restaurant, lobby mojito bar, and tranquil garden, which features herbs and fruit trees used by the hotel kitchen.

An offshoot of the highly acclaimed restaurant Talulah’s Garden, this neighboring cafe and market offers a casual spot for eating in and gourmet foods and treats for taking out. Located directly on Washington Square park, the cafe serves wine and beer and premium La Colombe coffee. Talulah’s Daily is a comfortable place to enjoy healthy prepared foods and creative sandwiches, with many options for vegetarians. The gourmet shop offers a variety of unique non-perishable food treats that will survive your trip home.

Hotel Bo is a so-called design concept hotel, and its particular concept is the unification of contemporary and traditional Chiapaneco architecture and design. (Chiapaneco means indigenous to the state of Chiapas, where San Cristobal de las Casas is located.) The four elements—wind, water, fire, and earth—are central to the hotel’s aesthetic, with different design details, such as fireplaces and candles, alluding to these elements. Rooms are decorated with some local crafts, and beds are dressed with colorful spreads. The hotel really is in the heart of San Cristobal, within easy walking distance of markets, restaurants, and the city’s main sights, many of which are architectural gems dating back to the colonial era.