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Once known as Casa Cohen, Dôce 18’s eighteenth-century structure has been painstakingly restored and is now the city’s chicest forum for fashion, design, art, hotel-going and fine dining. Shopaholics go nuts, especially for the delicate, enigmatic bijoux at Sangre de Mi Sangre; fair-trade fashion at Amor y Rosas or the fabulous artisanal tablewares at Estanzuela. The on-site hostelry, L’Ôtel, is a claque of just ten impeccable habitats, exquisitely furnished, complete with rooftop pool. Restaurant Jacinto 1930 by Oaxacan chef Israel Loyola is the top table at this writing. Or kick the evening off with a tequila—we’re talking the good stuff—in the sleek Casa Dragones tasting room.

Most people know the Lou Ruvo Brain Health Center by its appearance—the nonlinear building was designed by Frank Gehry and bears the architect’s signature curves and twists. Inside, however, medical professionals perform incredible feats daily. The facility treats patients with degenerative brain diseases such as Alzheimer’s, Parkinson’s, and Huntington’s. Because the center is an active medical facility, access to the public is limited, but architecture fans are welcome to swing by, marvel at the undulating walls, and wonder how Gehry does what he does with metal.

Buda Bar, on the other side of the Havana tunnel in Cabaña, is a meditation center by day and a bumping party by night. Go after 10PM from Friday to Sunday to hear anything but reggaeton, play domino, or get your future told by an Osho card reader underneath the trees. Ask a young local for directions, as the spot is somewhat secret!

A local institution, situated since 1953 in a 1692 adobe hacienda with brightly colored walls and a pretty courtyard, the Shed is deservedly famous for its smoky chile, just-hefty-enough blue corn tortillas, and classic recipes. Its sister restaurant, La Choza, is another local favorite. “We don’t have ambition to do a lot more,” says co-owner Courtney Carswell. “We just do what we do.” And they do it well.

Montes + Mugica is a furniture studio and clothing store that devotes itself to good, clean taste. It’s been in the family for generations, but each generation has brought a new style to the shop. The young brothers José and Javier bring a distinct affinity for all things Nordic, resulting in a gorgeous, hip aesthetic and real treasures for sale. Don’t miss their monthly pop up market in their other building, Espacio La Central.

Nestled in a corner of shops off the well-heeled boulevard de la Madeleine, the shop approaches many of their 50 some mustard varieties like beer, offering them fresh and on tap. Flavors range from the ultra classic (course ground à l’ancienne, tarragon, white wine, honey) to the rather unique (black olive, mushroom, cognac), many of which are unavailable outside Paris and Dijon. Aside from being a fantastic spot to pick up gifts, the shop is a beautifully potent homage to Antoine Maille’s original vision and the country’s favorite condiment. No need to travel to Dijon for a taste of Maille, the legendary mustard producer (though I recommend it). Just add their Paris boutique to your travel itinerary!

Mexican Independence is celebrated on the night of September 15 and throughout the day on September 16. On the night of the 15th there are celebrations called “El Grito” (the shout or cry of independence) that take place in the plazas and main squares of cities throughout the country. In Oaxaca people gather in the Zocalo and at 11 pm the governor comes out on the balcony of the Palacio de Gobierno and leads the shout, to which the crowd responds enthusiastically "¡Viva!” after each of his cheers. Following the grito, there are fireworks, and people wave flags, and throw confetti in an enthusiastic display of patriotic feeling.

No wonder the lines to get inside St. Peter’s Basilica are some of the longest in Europe: It’s home to world-famous architecture (many consider the dome atop St. Peter’s Basilica to be Michelangelo’s greatest achievement), one of the best views of Rome, and, oh yeah, the pope. The best way to visit this legendary site is to stroll in just after its 7 a.m. opening, make your way up to the dome, and look outside: You’ll get the spectacular view practically to yourself. You can take a free English-language tour if you visit between October and May. And keep in mind, there’s a strict dress code.

For 20 years now, the Spring Mountain corridor north of the Las Vegas Strip has been a hotbed of hot pots—and every other Asian dish under the desert sun. When celebs such as Anthony Bourdain and Penn Jillette raved about the real-deal northern Thai cuisine at Lotus of Siam, chowhounds followed. Tell your friends you’re finally making the trip out to the strip mall and they’ll tell you to avoid the items you can order from the takeout joint at home: no pad thai, no chicken satay. They’re right. Dive into the last page of the menu, the one about dishes from Northern Thailand, then entrust your tastebuds to the award-winning hands of Chef Saipin Chutima and try her larb or the jackfruit curry, anything with ground pork sausage, the khao soi (egg noodles and meat in a coconut curry sauce), the nam prik ong (a chunky mix of pork, tomato, and red chili, served with lettuce and raw vegetables), or the whole fish with chilis. The food is spicy, yes, and the afterburn is serious, but the depth of flavor is sublime enough to make you weep with regret the next time you have to call your local takeout place for delivery.

Surprisingly enough, you can round the point at Point Dume and discover your own hidden nooks to spend the day. With cliffs at your back and a private beach with decent size waves in front of you, it’s not a bad place for a picnic.

Art isn’t the first thing that comes to mind when you think of Vegas unless you’re familiar with the term kitsch. However, Sin City has always looked to please almost every palate and many impressive art exhibitions and theatre are proving to be a worthy alternative to the neon lights of the slots. You may head to old Vegas for a cheap dinner and a show but have you ever thought of dinner and a Picasso? At Picasso in the Bellagio Hotel & Casino, you can dine beneath the original paintings by Picasso himself. It’ll certainly cost you at Julian Serrano’s restaurant and you may even feel as though you end up paying for one of the masterpieces upon the wall but the food and service are memorable. Try to get a table near the windows or outside on the patio for a view of the fountains. Can’t afford an entire meal but love Picasso? Head to the bar for a drink.

If you have time, you could travel nearly two hours south of the capital into wine country to dine at the outstanding Miguel Torres restaurant near Curicó, part of this Spanish winery’s headquarters--or you could dine at their outpost in the upscale area known as El Golf. The focus is on blending seasonal Chilean ingredients to showcase their ample portfolio of wines with small plates and tasting glasses rather a full meal. For any meal, be sure to kick off with their pink sparkler, Santa Digna Estelado made from the traditional “país” grape. The winery supports many small, organic producers to make their wines and this is just one example. Salud! Isidora Goyenechea 2874, Las Condes Phone: 56 (2) 2245 7338 Photo: Miguel Torres Chile

San Juan Cemetery lies on the coast adjacent to El Morro (San Juan’s beloved fort) and nestled in the district La Perla, a rougher part of town. Its statues and tombs make it as beautiful as a New Orleans cemetery. Exiting El Morro, head down the grassy field to your left to catch this flustering overhead view. On this day, a powerful storm was rolling in, casting everything in gray.

A UNESCO World Heritage site, this hotel was the home of Hispaniola’s first governor, Nicolás de Ovando, and one of the first colonial structures built at the top of cobbled Calle Las Damas (the first paved street in the Americas). Built in 1502 and connected in 1974 during a reconstruction ordered by then President Joaquín Balaguer, the three stone buildings retain their original coffered ceilings, massive arches, tile floors, and brick and stone walls. In addition to 92 rooms and suites, including a dozen Imperial Club rooms overlooking the Ozama River and Don Diego Harbor (Room 4015 has a particularly stunning view and gorgeous bathroom), you’ll find a lovely reading nook, gourmet restaurant, lobby mojito bar, and tranquil garden, which features herbs and fruit trees used by the hotel kitchen.

An offshoot of the highly acclaimed restaurant Talulah’s Garden, this neighboring cafe and market offers a casual spot for eating in and gourmet foods and treats for taking out. Located directly on Washington Square park, the cafe serves wine and beer and premium La Colombe coffee. Talulah’s Daily is a comfortable place to enjoy healthy prepared foods and creative sandwiches, with many options for vegetarians. The gourmet shop offers a variety of unique non-perishable food treats that will survive your trip home.