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Don’t let your eyes fool you. Villa Panza is a not just a gorgeous 18th-century estate. The villa and grounds host the spectacular Panza Collection, an amazing grouping of art from the 1960s through 1980s, with particular attention to American artists. The individual pieces (paintings, sculptures, drawings) are incredible but what makes the collection are the site-specific installations from artists such as Dan Flavin.

Seminal American artist Georgia O’Keeffe drew inspiration from the lunar landscapes of New Mexico. Follow in her footsteps at some of her favorite painting spots—The White Place, The Black Place (part of Bisti Badlands), and the home of the “Lawrence tree”—or splurge on a 10-day art retreat at her remote studio getaway, Ghost Ranch. View her most famous works and her letters and journals at the Georgia O’Keeffe Museum in Santa Fe, then stop by her adobe studio to see her paints, easel, and impeccable mid-century furniture. Grab a Georgia O’Keeffe biography at Bode’s, her favorite general store in the center of Abiquiu, then round off your art odyssey with “The O’Keeffe Table” at Eloisa: a five-course tasting menu that pays tribute to the foods O’Keeffe cooked at home. —By Edmund Vallance

On a perfect spring day, Boston turns into a giant walking tour. The city’s top attractions tend to spill over from one to the other, inviting visitors to just keep going. On other days? Well, luckily there’s the T. For one of America’s most celebrated walking tours, walk the Freedom Trail, which takes you to 16 sites central to American history, including the Massachusetts State House and the Paul Revere House and so much more. Here are some of the best things to do in Boston.

Uncorking Switzerland’s Secret

What could an Alaska local ever discover on a voyage through the Inside Passage? Just the essence of the place he thought he knew.

Hoi An’s iconic noodle dish was tangled in mystery for decades. Then writer David Farley came to town.

Start by seeking out the country’s beer-brewing monks.

San Francisco’s seven hills and extensive coastline offer plenty of impressive views; why not enjoy them with a delicious meal or bubbly drink? The Burger Bar on the top floor of Macy’s and the Rotunda at Neiman Marcus overlook Union Square. Bay-side eateries like Epic Roasthouse offer travelers water views, while the Cliff House (shown) and the Beach Chalet are right on top of Ocean Beach. To see the city glittering at night, visit the Top of the Mark bar at the Intercontinental Mark Hopkins Hotel or the Americano at the Hotel Vitale, in full view of the Bay Bridge’s Bay Lights.

At Salt Water Farm, students return to the land—and the sea—to learn forage, fillet, and feast.

Brasswood Bar + Kitchen is part of Brasswood Estate, a sprawling complex at the north end of St. Helena, comprises a winery, tasting room, restaurant, café, art gallery, and bottle shop. The property was formerly known as Cairdean Estate but was rebranded in 2016. Like many eateries in Napa, this one features local bounty—produce and protein grown in Napa and surrounding counties. Executive chef David Nuno specializes in Italian cuisine, so everything has a bit of a Mediterranean flair. In the restaurant, the duck Bolognese, with duck from Sonoma, is rich and savory; the herb-crusted lamb chop is made with local lamb, as well. The artisan bakery serves food in a less-formal setting; here, pay for your white corn soup or mushroom salad at the counter, and enjoy it by the fountain on the plaza outside.

A journey into Morocco’s Berber territory, where tradition and modern life meet.

The Grand Central Oyster Bar celebrates its 100th anniversary this year as a New York institution. Located in the lower concourse of Grand Central, it serves over 25 varieties of oysters daily. There is a huge menu of American seafood—chowder, fried clams, lobster rolls, clams casino—whatever you are looking for, they will have it. The Oyster Bar is also famous for its architecture—the beautiful arched tile ceilings are the hallmark of famed Spanish architect Rafael Guastavino, who left his unique stamp across NYC. Take your pick from three different seating areas: a series of old-fashioned, U-shaped counters which seem to be popular with tourists and locals; the oyster bar, which would be perfect for singles or those dining in pairs; and the saloon-type restaurant in the back, popular with the business crowd. Wherever you are sitting, it will be bustling with activity. While there are several other oyster bars in the city, the Grand Central Oyster Bar offers a piece of New York history. It’s like stepping back in time, a retro celebration of old Americana that generations of locals, tourists and travelers have visited over the years. My suggestion is to stop in for fresh oysters and cold beer at the bar.

You can’t talk about cafés and coffee shops in Los Angeles without mentioning one of its most popular places: Urth Caffé. For an organic fix, there’s no better place. There are a number of locations throughout the city and in Orange County, including Santa Monica, Melrose, and Beverly Hills. With their trendy ambience and large outdoor patios, they are the perfect place to spend a sunny afternoon, especially if you love herbal teas, organic coffee, and green-tea Americanos—and if you’re keen to spot celebrities around the metropolis. Aside from delicious drinks, they also have a wide selection of vegetarian and vegan food options.

On a hilltop perch overlooking 8,000 acres of grounds designed by famed landscape architect Frederick Law Olmsted, the Inn on Biltmore Estate’s 210 rooms and suites evoke traditional 19th-century manor houses, with dark mahogany beds and desks, billowing window treatments, and comfortable overstuffed chairs; book a room with a balcony to breathe fresh mountain air while appreciating views of rolling hills—or simply take in the vista from the hotel’s veranda. The formal dining room showcases seasonal specialties using estate-raised cattle and lamb, vegetables from the on-site garden, and wine from the property’s own winery, where you can participate in a free tasting, then ride back in a complimentary shuttle. If you’re looking for something more casual, the lobby lounge and library bar offer salads and sandwiches—and no dress code. But the main attraction is the 250-room Biltmore château, the Gilded Age mansion George Vanderbilt built here in the late 1800s, and its 16th-century tapestries, Renoir and Sargent originals, and 65 fireplaces.

While most travelers visit the Cape Winelands in the spring or fall, Delaire Graff is a year-round destination. At the estate’s Wine Lounge, guests can enjoy a glass of wine on the outdoor terrace during the summer, or cozy up by the crackling fire in winter, enjoying the famous view through floor-to-ceiling windows. The wines here range from elegant reds with soft tannins to white wines that capture the freshness of the harvest.

Those craving a more complete experience should know that Delaire is also a Relais & Châteaux property with an on-site spa and six separate lodges. Book a massage and you’ll enjoy full use of the pool, steam room, and sauna as well as a tasting in the Wine Lounge post-treatment, or stay overnight in the Owner’s Suite, which features a heated plunge pool and views of Table Mountain.