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The D.O.M., which opened in late 2013, is a five-star boutique hotel in the heart of Rome’s historic center. Originally built as a 17^th-century noble palace, the property was subsequently converted into a monastery, then Ministry of Justice offices. Its current design, which blends architectural elements from its previous uses, was entrusted to architect Antonio Girardi, who has seamlessly married Renaissance reverence and modern design.

Thanks to the previous ecclesiastical incarnation, rooms are intimate and many have low ceilings. Dark gray and brown hues mingle with velveteen, brick, and wood, creating a cavernous feel in the ground-floor common areas, which contrast with the bright and open rooftop terrace and its views over Rome’s Renaissance quarter and across the river to Trastevere. On the ground floor, a small reception area precedes the hotel bar and restaurant, as well as a small enclosed terrace.

Philly visitors, don’t miss a stop at Pennsylvania’s most-visited museum, the Franklin Institute. Allow ample time to make your way through its multiple floors, where entertaining and hands-on educational displays await. Crowd-pleasing permanent exhibits include a 350-ton locomotive, a giant walk-through heart, flight simulators, a high-wire bike, and fun interactive areas covering electricity, sports, machines, motion, and technology. The museum also includes an observatory, planetarium, and IMAX theater. The institute frequently hosts after-hours events, most notably star-gazing, and recently opened two escape-room-type attractions.

I think the most appealing aspect of Old San Juan is the architecture and design of the city. Residential apartment buildings have been converted to designer boutiques or little B&Bs, and interior courtyards invite hungry guests to relax and unwind in the shade.... I’ve been to this area multiple times and still I manage to find a street I’ve never wandered down. Some are more popular than others, in particular Calle San Sebastian, which hosts eateries, bars, and shops, and Calle San Francisco. At the corner of this street is my particular favorite, Franky’s antiques. It’s in a four-story building, loaded with vintage goodies. There’s so much to see, one trip is not enough. If you want to shop, consider wandering all morning and into the early afternoon. You’ll be delighted by all the unique shops. Then, take a break at my favorite restaurant, Triana, for Spanish-style tapas and their famous sangria. It’s a must-stop place any time I’m in the old city. You don’t need a car to get around. Just park at one of the garages and explore by foot. There’s lots to see and do in Old San Juan.

Palazzo Mezzanotte (Mezzanotte Palace) is the seat of Italy’s stock market and a great example of 1930s architecture. Designed by architect Paolo Mezzanotte it was considered the most tech building of its time. 21st notoriety can claim artist Maurizio Cattelan’s comment to finance in the form of a large hand with extended middle placed in the very center of the piazza.

The Pennsylvania Academy of the Fine Arts is the nation’s first museum and school of fine arts, and home to an outstanding permanent collection of American art, including Thomas Eakins’ medical painting “Gross Clinic”. Throughout the year, PAFA presents special exhibitions and work by some of the region’s most talented contemporary artists. The galleries are contained in two separate buildings, the Historic Landmark Building (pictured), a spectacular architectural gem designed by Frank Furness and George W. Hewitt, and the new Samuel Hamilton Building at 128 North Broad Street. Be sure to visit Lenfest Plaza, a public space adjacent to the Academy to check out Philadelphia artist Jordan Griska’s fantastic sculpture made from a former US military plane. PAFA’s gift shop, housed in the new Hamilton Building, is a wonderful place to shop for unique accessories, arts, crafts and paper goods.

The Place Bonaventure is widely recognized as one of the most important buildings constructed in Canada in the 1960s, though that’s not to say it’s universally loved. It’s a regular contender for the title of Montreal’s ugliest building. For the student of architecture, however, whether armchair or otherwise, it’s worth a visit to see an outstanding example of brutalist architecture. Architect Raymond Affleck’s vision was to turn the city inside-out in a building appropriate for its location in a cold climate. The Place Bonaventure was designed to include a conference center, hotel, and several floors of retail space, all along internal streets while the building presents a foreboding exterior of ribbed concrete (echoing the design of the seminal Architecture School at Yale University by Paul Rudolph) to the street. The entire complex included 3.1 million square feet of floor space, making it the largest building in the world when it was completed (in 1967). Much of the retail space was converted to offices in later renovations, though the conference center and the hotel (now the Hôtel Bonaventure Montréal) remain. The photo here was taken inside the hotel—a walk around their common spaces will give you a taste of Affleck’s vision for a new urban architecture.

Playful art and sculptures are the centerpiece of the winery, Clos Pegase. A collection of sculptures by famous 20th-century artists greets visitors outside, and the collection continues in the courtyard and tasting room. The owner, Jan Shrem, believes that great art is best shared with the public. The architecture of the Napa Valley winery is also creative—architect Michael Graves designed the grand building with elements that are partly contemporary and bold and partly classical. The wines are produced only from estate-grown grapes. Tours are offered daily at 11:30 a.m. (all ages) and 2:00 p.m. (21 and over only).

The Swiss-born modernist giant was many things: architect, painter, sculptor, graphic artist, furniture designer, and writer. This museum, also known as the Centre Le Corbusier, is located in the Zürichhorn park, and offers a chance to view examples of his work across all these realms—the most striking of which is the building itself, Le Corbusier’s last, a steel-and-glass masterpiece marked by multicolored enameled panels.

Marilyn Monroe once proclaimed that her favorite swimming pool was at the Arizona Biltmore. And Irving Berlin, obviously a person who didn’t know how to relax, is said to have written “White Christmas” while a guest at the hotel. Other musical guests have included Frank Sinatra and Sammy Davis Jr., who were known to play on a piano in the lobby. But that’s history, and the Jewel of the Desert, as the 90-year-old hotel was once known, is now just one more sparkling gem in a treasure chest of Arizona resorts. To continue shining, the Biltmore underwent a major renovation that was completed in late 2016. Much of the update focused on restoring the hotel’s original main building, but the guest rooms, meeting spaces, ballrooms, and spa were also polished. The contemporary style that now dominates the Biltmore was inspired by Frank Lloyd Wright, who played a significant role in determining the hotel’s original look. In the guest rooms, Wright’s influence is most notable in the wall coverings, embossed with a design similar to that found on his “Biltmore Blocks,” used in the construction of most of the resort. Of course, for guests who didn’t come for the history, or the design lecture, there are still the eight swimming pools, seven tennis courts, and, next door at the Arizona Biltmore Golf Club, 36 holes of golf.

Dresden’s architectural and cultural highlight, the Zwinger was commissioned by Augustus the Strong and built between 1710 and 1728 by architect Matthäus Pöppelmann in cooperation with the sculptor Balthasar Permoser. Originally designed as an orangery and setting for court festivities, it’s one of the best examples of late Italian Baroque architecture in Germany. Today, its cultural treasures are immense, ranging from the two-floor Semper Gallery (full of Old Master paintings, including Raphael’s Sistine Madonna) to a royal porcelain collection with Chinese, Japanese, and Meissen examples. Visitors will also find a Museum of Mathematics and Physics (with antique sextants and globes), the Nymphs’ Bath (one of Europe’s most beautiful Baroque fountains), and a gilded gate flanked by long, arched galleries. The venue also hosts musical and theater performances, among other events.

Belgium is famous for its Art Nouveau architecture from the late 19th and early 20th centuries. While many architects were experimenting with this new style, Victor Horta is Brussels’ undisputed father of Art Nouveau. Many of his stunning creations are still in use around the city, like the Hôtel van Eetvelde on Place Ambiorix, added to the UNESCO World Heritage Sites list in 2000. While the Hôtel van Eetvelde is only open to the public during special ‘open heritage’ days in Brussels, it’s well worth walking through the neighbourhood, rich in dramatic architecture. To see inside one of Horta’s creations, visit the Horta House Museum, in the St. Gilles neighbourhood. This was Victor Horta’s home and studio and he designed every last detail, inside and out. It is also a UNESCO listed building. Guided Art Nouveau walks are provided by many tour companies, including the Brussels Greeters volunteer network. You can also download a self-guided tour map from the Visit Brussels website.

This hotel is on our list of The 11 Best Hotels in Chicago.

Chicago invented the skyscraper, and some of the world’s most elegant examples define the city’s skyline. You can stay in the coolest one of them all, designed by German American architect Mies van der Rohe and run by Langham Hotels. To access the Langham Chicago’s minimalist-yet-opulent 268 guest rooms (including 48 suites), you must first check in at the second-floor lobby; its ceiling is hung with silver pebbles, its sofas populated by stylish guests, and its David Rockwell–designed Travelle restaurant alive with music and bites by executive chef Damion Henry during coveted afternoon teas.

The former IBM building with a black exoskeleton also houses a Chuan Spa, which specializes in such Eastern therapies as acupuncture, cupping, and gua sha. A 67-foot-long indoor pool and full-service fitness center are available to all guests.

Anyone spending the night in the rooms, with floor-to-ceiling glass windows framing Chicago views, has access to one of the city’s best concierges, who can organize a River North food tour, a Frank Lloyd Wright walking excursion, or a mixology class at Travelle. Don’t leave without taking a photo beside Jaume Plensa’s “Anna” sculpture in the Wacker Street lobby—then walk over to Millennium Park to see his larger works on display.

Set across from the University of Pennsylvania, the Inn at Penn holds its own against the new Center City crop and is one of the most technologically advanced hotels in Hilton’s portfolio. Built in 1999, the hotel was renovated top-to-bottom in 2011, solidifying a stuffy-enough Ivy League air. Above an efficient wood-paneled check-in, a double-fireplace library lined with classic tomes creates a sophisticated lobby-cum-cocktail lounge. A Frank Lloyd Wright–inspired aesthetic is pervasive with geometric lamps, wood-paneled walls, Craftsman wood furnishings, and the hotel’s riff on the architect’s iconic font on all signage. The Inn is teched out with free, fast Wi-Fi; TeleAdapt MediaHubs connecting phones, tablets, or computers directly to high-def TVs; and iPads accessing hotel services and information in multiple languages. The Inn’s environmental stance is also impressive: fabrics, wall coverings, and bathroom tile are made from recycled materials; energy-efficient lighting, heating, and cooling is state-of-the-art, and WaterSense showerheads ensure no water is wasted.

The 245 guestrooms and suites are classy, efficient, and relatively spacious, though it’s worth upgrading to a suite for a separate sitting area. Gold, leather, and wood hues are complimented by pops of red and orange with large work desks. Thanks to the 2001 renovation, the bathrooms are big, have glass-encased showers, and are stocked with Crabtree & Evelyn amenities.

Every April, thousands of visitors descend upon Augusta, Georgia for The Masters golf tournament. While the azaleas and dogwoods that line the fairways are beautiful, the streetscape outside the Augusta National Golf Club is a car-dominated aesthetically unfortunate collection of chain restaurants and strip-mall-churches--not exactly what you’d expect if you were to believe the city’s official nickname of “The Garden City.” Drive just ten minutes away, however, and you’ll end up in the Augusta Downtown Historic District, set aside by the National Park Service due to its collection of architecture from the 1780’s to the present. (Sherman didn’t march through this part of the state, sparing it the Civil War damage that destroyed Atlanta.) Georgia’s second-largest and second-oldest city might not be a ‘destination’ in the way that Savannah and Atlanta are (unless you love golf), but if you’re in town and architecture interests you, it’s worth spending some time down by the Savannah River. One of the tallest structures is the Lamar building--built in the 1910’s. In the mid-1970’s it was topped by a glass penthouse, designed by...I. M. Pei--the same architect who is perhaps best known for the now-iconic glass pyramid that dominates the courtyard of the Louvre in Paris. Augusta’s piece of Parisian-linked-architecture-fame is locally known as “the toaster.” Just slightly irreverent...