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As obvious as it may sound, what sets Sanctuary apart from any other Scottsdale resort is location. Sitting on the north side of Camelback Mountain yet minutes from downtown Scottsdale, it has a balance of desert mountain isolation and easy access that no other Scottsdale resort can match. Since Sanctuary opened in 2002, the combination has especially appealed to publicity-shy celebs (Beyoncé and Jay-Z even stayed here while on their honeymoon). The views from the floor-to-ceiling windows in the adobe casitas look out at the mountain and across Paradise Valley. The casitas have wood-block floors, glass-tiled showers, and, in many of them, oversize tubs with romantic votive candles.

American entrepreneur Michael Evans and Argentine winemaker Pablo Gimenez Riili joined forces to create an unparalleled viticultural paradise for wine lovers from around the world. Set on 1,500 pristine acres in the heart of the Uco Valley, the Vines Resort & Spa is a haven of laid-back luxury with a robust offering of culinary and wellness activities, winemaking endeavors, and outdoor adventures. Every aspect of the hotel is designed to share Mendoza’s natural beauty, superior wines, and Argentina’s warm culture through a tailored guest experience provided by the resort’s “Gauchos”—personal concierges and tour guides who curate one-of-a-kind itineraries for visitors.

The resort’s 22 spacious villas have ample indoor/outdoor living space, with wood-burning fireplaces, open-air fire pits, plunge pools, hot tubs, and private rooftop terraces with 360-degree views. Siete Fuegos, the resort’s signature restaurant, showcases open-flame grilling techniques mastered by Argentina’s acclaimed chef Francis Mallmann. The fitness center and yoga studio look out to the Andes, while three miles of running trails weave through the property’s vineyards. There’s never a dull moment at the Vines, with horseback riding, hiking, biking, cooking lessons, and winetasting at your fingertips—unless lounging is your preferred activity, in which case a cabana next to the 1,000-square-foot infinity pool will be calling your name.

Located in the heart of Whalers Village on Kāʻanapali Beach, Hula Grill is a busy hangout with live music seven days a week. You can sit for a meal in the open-air dining room, but the real party happens at the restaurant’s Barefoot Bar, right on the water’s edge. Kick off your shoes and sink your feet in the sand, then order a Barefoot Brew (made specially for the bar by Maui Brewing Co.) or cocktails like piña coladas, mojitos, and Maui Mules with organic vodka. Also on offer are a range of non-alcoholic drinks, from house-made sodas and fresh-squeezed juices to local kombucha and pure coconut water, as well as a solid food menu that highlights Hawaiian farmers and fishers. For a great deal, head here for Aloha Hour, which takes place daily from 2:30 p.m. to 5 p.m. and includes special prices on pupus and drinks.

A cultural hub for Turkish and international art, Istanbul Modern opened in 2004 as a permanent home for the contemporary Istanbul Biennial. The 8,000-square-foot warehouse sits along the Bosphorus next to the Golden Horn, a historically important port for thousands of years. The water views rival the exhibitions for your attention and appreciation, and the museum has an excellent restaurant and terrace to take advantage of the location. Back inside, the permanent collection shows contemporary and modern artists from Turkey, with rotating exhibitions of photography, design, and new media. The downstairs cinema has several screenings a week of films that complement exhibitions or feature distinctive work, often accompanied by panel discussions. The gift shop is one of the best places to buy unusual and beautiful souvenirs such as upcycled jewelry and kids’ coloring books of museum art.

Hillside Farmacy is a farm-to-table restaurant in Austin built around a pharmacy theme. While it may sound odd, the execution is brilliant, with incredible food and wonderfully eclectic design. The restaurant space was formerly the home of a 1920s pharmacy owned by Austin‘s first African-American pharmacist. The decor features authentic apothecary items (from a different 1920s drugstore)—a vintage collection of medicine bottles, antique cash registers, tin ceilings, and wooden cabinets. But it’s the “F” in the deliberately misspelled Farmacy that nods to the emphasis on simple, fresh food. The restaurant works with local food purveyors and regularly changes the menus around the highest-quality seasonal ingredients. Local cheese, homemade pate, artisinal breads and pastries, raw bar, charcuterie are all available here. Dishes include bangers and eggs, buttermilk bisquits and gravy, and bison tartare. Other perks include an old fashioned soda counter and a shaded outdoor patio. If I were a local here, this would definitely be one of my favorite go-to places.

If you love art in all its many forms, the Museum of Fine Arts (MFA) in Boston is a ‘must-see’ destination. They have a great collection of Impressionism and Asian art works, from Monet and Van Gogh, to Chinese furniture and Japanese paintings, as well as the Egyptian collections. In addition, their newly opened west wing contains many stunning pieces of American art. Besides the arts, there is a cafe, a restaurant, gift shops of course, and a mini cinema for special shows. To get there: The MFA has its own subway stop called, what else, the MFA. If you drive, there are parking garage options as well. You can easily spend half a day here—or more!

Run by well-known chef Jeff Balfour, Southerleigh brings cross-cultural cuisine to the bustling Pearl Brewery complex. Here, the seasonal menu ranges from crispy fried half-chicken with coffee-crusted bacon and thyme red-eye gravy to Gulf red snapper with charred tomato sauce piquant and pickled fennel salad. Housed in a historic building that was once Pearl’s Brewhouse, Southerleigh also references its past with an on-site brewery and nearly two dozen beers on tap.

The name says it all: To dine at Bliss is pure euphoria. In an intimate space with just 52 seats, this Southtown restaurant offers a dining experience you won’t soon forget. Mixing hearty classics with Southwest-inspired cuisine, the menu ranges from braised beef short ribs with buttery mashed potatoes to vegetarian enchiladas stuffed with roasted butternut squash, cremini mushrooms, zucchini, bell peppers, eggplant, and cheese. Appetizers are equally enticing, especially the Japanese hamachi sashimi tostadas and the oyster sliders, served with candied bacon on buttermilk chive biscuits.

There’s nothing quite as magical as a horse-drawn sleigh ride through the snowy wonderland that is the Alps in winter. For the most romantic option, head to Salzburg and take a ride through the Salzach River Valley, past snow-topped Alpine chalets, quaint inns, and huge glaciers. Panorama Tours offers excellent December tours, during which guests snuggle beneath warm blankets before warming up with traditional Styrian cuisine in Ramsau.

The Coronado Bridge links San Diego to Coronado Island—and the present to the past. In the span of just 2.12 miles, you’ll travel from the digital age to a century when “electrified” hotels were practically unheard of. When the Hotel Del Coronado debuted in 1888, its electric lights and telephones made a sensation—as did its resplendence. In 1892, a young guest named Noel proclaimed in a letter to her family back east that “the red and the white between the bluest sky and the bluest water is like a beautiful dream in a fairy story.” Legions of A-listers have checked in ever since, as a who’s who of vintage portraits attests. But while a stay here is delightfully nostalgic—featuring bike rentals, beachside cabanas, and evening clambakes—the 757-room hotel doesn’t live entirely in the past. Take advantage of its upscale spa, spin classes on the beach, and restaurants serving updated takes on coastal cuisine along with creative cocktails. In the historic Victorian Building Suites, you’ll find modern coastal-chic interiors, streaming TVs, and, of course, Wi-Fi. The Beach Village Suites include additional modern luxuries—like a Sub-Zero fridge and dedicated concierge to help you fill it.

Even though Thailand is thousands of miles from Telluride, Siam has perfected an edible ode to the country. In fact, the food here is so good that 5280 magazine named Siam one of the best Thai restaurants in the entire state of Colorado. At this downtown spot, Thailand-born and -raised chefs cook the dishes of their home country, using as much local and organic meat as possible. The king crab and lobster tempura, pineapple-and-red-curry mussels, and peanut-dusted pra ram stir fry will have you so besotted with Thai cuisine, you’ll be digging for your passport to take the next flight to Bangkok.

A recent addition to the Puerto Rican capital’s culinary scene are food hall–style spots where diners can choose among multiple kiosks, or stalls, each featuring a distinct kind of cuisine. Lote 23 is one such spot, located in the working-class neighborhood of Santurce. More than a dozen food entrepreneurs have fare on offer here, from pizza and tacos to bao and burgers. If you just need something to cool yourself off in the tropical heat, there are popsicles and cocktails, too. The alfresco eating area has plenty of picnic tables where you can sit and enjoy whatever you’ve ordered.

These days, a hip design hotel isn’t worth its salt unless it’s also home to an almost painfully trendy bar. But when Story Hotel first opened in 2009, on the border of two of Stockholm’s coolest neighborhoods, it set the standard to which all of the city’s subsequent boutique hotels would be held. The Story formula is deceptively simple: take one historic building in an achingly cool European capital and strip it down to exposed brick and concrete, and original hardwood floors, before decorating it with a sleek, unpretentious style that epitomizes Scandinavian design. Add a sprinkling of colorful graffiti art, and pair faded Persian rugs with collaged photographs and leather chairs. Make sure some rooms are small and affordable, while others are spacious and decadent.

The cuisine needn’t be fancy, but it ought to be high quality, just as the cocktails must be inventive and delicious. And don’t let the DJ-accompanied scene turn pretentious; everyone should feel welcome, and among friends. Story’s formula works, and there’s a reason this original boutique hotel is still one of Stockholm’s best.

The understated and modest villas at the Hoshinoya Taketomi Island resort are a far cry from the characterless concrete and stucco of many beach resorts, but then again, this is Japan, where tradition and elegant simplicity are standard. The island of Taketomi prohibits modern buildings and encourages the traditional practices of red-tiled roofs and gukku stone walls with embedded talismans. Accommodations are either Japanese-style with tatami mats and futons, or more western with wood floors and modern furniture; all have deep soaking tubs, private gardens, and floor-to-ceiling windows that can be fully opened to let in the outdoors. The restaurant serves nouvelle French cuisine featuring island seafood and local ingredients, and the lounge encourages guests to unwind with a beverage and a book. For more active stays, the swimming pool is heated and shaded by banyan trees, and guests may borrow a bicycle to explore the island’s white coral sand beaches and watch the sun rise and set from the observation deck. The resort is reached by ferry and a shuttle from Ishigaki port, and visitors get around the island by water buffalo cart rather than car.

Vegetarian food has never looked better than at WUJIE, a temple to some of the world’s freshest cuisine. Dishes here are creative, beautifully plated, and a mélange of textures. The kitchen makes all of its tofu and milks (almond, rice, etc.) in-house and uses seasonal and domestic ingredients whenever possible; so those mushrooms in your radish dumplings come straight from southern Yunnan province. WUJIE shies away from mock-meat dishes, though there are a few delicious exceptions, including a tonkotsu-inspired cutlet of minced mushrooms wrapped in tofu skin and doused in crispy panko crumbs. The Taiwanese-and-Chinese-fusion restaurant has three branches, one at the border of Xujiahui and the French Concession, another on the Bund (prix fixe menu only), and a third in Lujiazui, inside the Shanghai World Financial Center.