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Want hot chiles? mild peppers? powder? paste? Across from the old Spanish mission in Tumacácori, you’ll find it. For decades, family-owned and family-run Santa Cruz Chili & Spice Co. has been providing flavors in Southern Arizona. There’s even a mini Western Museum...and of course, you can sample the sauces and salsas... The Santa Cruz valley, between Tucson and Nogales, is one of the oldest continually-farmed regions in the U.S.; for four thousand years, native peppers, beans, squash, cactus and corn have been cultivated, even here in the desert. Then, beginning in the 17th century, Spaniards introduced Mediterranean plants: grapes, figs, pomegranates, figs, quince...and cattle ranching. A small garden on the grounds of the Tumacácori mission across the road from the Santa Cruz Chili Co. still grows some of these heirloom crops. A visit to the mission and spice market make for a great afternoon or day trip from Tucson. Go south from Tucson on I-19 for about an hour. (Note: I-19 is marked in kilometers, not miles; quirky.) Take Exit 29, turn left, then turn north on the old highway, and you’ll see the big chile-pepper sign on the left, just before you get to Tumacácori mission National Historical Park. The store is closed on Sundays.

Pueblito Los Dominicos, an artisan village in eastern Santiago, is named after the church bearing the same name. This quaint center offers many quality handicrafts, from leather goods to lapis jewelry, Mapuche silver, and textiles. The setting is picturesque and if the hunger overcomes you, there are tasty empanadas de pino (beef empanadas) to hold you until dinner. Apoquindo 9085, Las Condes (Metro Los Dominicos)

Located 100 miles south of Santiago, the Colchagua Valley has in the past decade become one of Chile‘s wine hotbeds for the production of robust red wines. Stretching from the Andean foothills in the east through the coastal mountains to west, always following the Tinguirrica River, the valley is renowned for its “big” reds like Cabernet Sauvignon, Syrah, and Chile‘s flagship wine, Carmenere. The majority of the vineyards lie in the center of the valley around the small country town of Santa Cruz with its charming colonial plaza and several hotels. New vineyard plantations are also extending into the hillsides in prestigious sub appellations like Apalta nearby and to the west towards the sea. Besides red wine, Colchagua is also steeped heavily in Chile’s country traditions and cowboy culture as an agricultural valley, making it an ideal weekend getaway. For wine enthusiasts, every March during harvest the valley puts on its annual harvest festival during a whole weekend with tastings from valley wineries, regional food, music, dance, and local color.

Golf enthusiasts will find plenty to love at Pompano Beach Club—the family-owned resort is practically next door to the world-famous links of Port Royal. But the former fishing club is also a haven for anglers of every stripe: You can grab a complimentary rod from the hotel staff and wade out nearly 400 yards on the nearby sandbar to cast for bonefish and—what else?—pompano, or charter a vessel to catch yellowfin tuna and mahi-mahi on a deep-sea voyage. Back on land, the 75 guest rooms provide laid-back ambience thanks to floor-to-ceiling windows perfect for enjoying panoramic ocean views. Better still, retire, rum swizzle in hand, to the terrace of the appropriately named Sunset Lounge to take in the postcard-worthy vistas.

Who hasn’t daydreamed about being an astronaut at least once? Thankfully, Space Center Houston makes it easy to learn about the great beyond. It’s the area’s No. 1 attraction for international visitors and the first Smithsonian Affiliate in the greater Houston area. The center features more than 400 space artifacts and several exhibits related to the past, present, and future of America’s human spaceflight program. It’s also home to the world’s largest collection of moon rocks and lunar samples for public view, and offers guests the opportunity to go behind the scenes to see NASA’s Johnson Space Center.

Que Bonita offers furniture from the Sierra Madre, textiles from Guatemala, Peruvian ceramics, Native American jewelry from the Southwest—all on the way to (or from) Mt. Lemmon on Tucson’s northeast side. This family-owned gallery/furniture/clothing store has been in Tucson for three decades. When in southern Arizona, check this place out for items from all over Latin America. (It’s only a couple doors down from a good pub, and next door to a hotel, too!)

Hiking the French Valley is part of the W-trek through Patagonia’s Torres del Paine National Park. It’s about 16 mi round-trip from Refugio Paine Grande to the French Valley Mirador, to see the French Glacier and the Paine Massif as close as you can get. The trail is diverse and only reaches a steep height at the last 5.5 km on the way there. You begin at Lago Pehoe and take grassy paths through the forested valley, on an terrain that the locals call “Patagonia flat,” i.e. an undulating up and down of several feet. On the way you’ll see tiny magenta--and edible--berries that taste just like apples; you’ll cross small glacial streams where you can fill up your water bottle with fresh, wild water. You’ll trek right by the Cuernos, or the “Horns,” another well-known set of peaks in Torres del Paine. Over the French River you go as you get deeper into the valley, over wobbly rope bridges. The final 5.5 km to the French Valley Mirador has you balancing on thousands of loose boulders on your way up. The very top of the trek feels like being in the middle of a Patagonian fishbowl: Paine Massif to your left, French Glacier in front, the Aleta de Tiburon (the Shark’s Fin) and the Cuernos to the right, and turquoise Lago Pehoe behind you.

San Francisco’s seven hills and extensive coastline offer plenty of impressive views; why not enjoy them with a delicious meal or bubbly drink? The Burger Bar on the top floor of Macy’s and the Rotunda at Neiman Marcus overlook Union Square. Bay-side eateries like Epic Roasthouse offer travelers water views, while the Cliff House (shown) and the Beach Chalet are right on top of Ocean Beach. To see the city glittering at night, visit the Top of the Mark bar at the Intercontinental Mark Hopkins Hotel or the Americano at the Hotel Vitale, in full view of the Bay Bridge’s Bay Lights.

Immediately adjacent to Loews Regency, the Sant Ambroeus Coffee Bar is one of the latest outposts of this popular group of New York, by way of Milan, restaurants. The original Milan restaurant opened in 1936, and there are now three others in Manhattan, as well as one in Southampton. The Park Avenue coffee bar has an Italian art deco decor, bringing a little bit of Milan’s style to the neighborhood, and several outdoor tables. Choose from a panini or one of Sant Ambroeus’s famous pastries.

Inspired by vibrant Southeast Asian night markets, D.C. chef Erik Bruner-Yang (of Toki Underground fame) and D.C. streetwear mogul Will Sharp created a sleek, two-story indoor/outdoor space that’s part menswear store, part café and restaurant. The first level is all about shopping, and the floor is lined with glass-encased displays featuring Sharp’s clothing line, Durkl, as well as a library full of designer sneakers. Upstairs, sip locally roasted Vigilante coffee while snacking on Frenchie’s pastries and desserts. The best part, though, is when you step onto the patio and take a seat at the open kitchen serving up Yang’s blazing hot and flavorful Cambodian and Taiwanese cuisine. Don’t miss out on the American Wagyu tartare, the Khmer tamarind salad, the steamed pork bao buns, and zha ji pai (Taiwanese fried chicken).

Yes, New Mexico actually has an official “state question"--since 1996, referring to the ubiquitous chile sauce, it’s “red or green?” Fortunately you don’t have to choose just one; the local way to say ‘can I have both’ is just one word: “Christmas.” If you’re driving through New Mexico on the way to Arizona and points beyond, the only town of any size on I-40 between Albuquerque and Flagstaff is Gallup. For road-trip food here, get away from the Interstate and its humdrum chain restaurants. Seek out Jerry’s--a block off old Route 66. You can’t miss the retro neon sign, and there’s often a line out the door for its New Mexico-style fare. Gallup is surrounded by Navajo, Hopi, and Zuni lands--you might well be one of the few non-Native-Americans eating here at breakfast or lunch. The restaurant allows local vendors to come in and show their wares--usually jewelry and bracelets--while you eat. (You can request a ‘do not disturb’ sign for your booth if you want.) “Hole in the wall” gets overused, but Jerry’s definitely fits that description. Nothing pretentious here--but the flavor of the chile sauce is as good as you’ll find in Albuquerque or Santa Fe. A recommendation: the flat cheese-and-onion-enchiladas, topped “Christmas” style with a fried egg on top. And don’t forget to sop up the sauce with the sopaipillas, saving some of the frybread to top with honey as a dessert afterwards...

Come to “El Güero Canelo” if you’re in southern Arizona. It’s a Tucson institution where you can get the best “Sonoran/Mexican hot dogs” north of the border... But what’s a Sonoran hot dog? It’s a wiener wrapped in bacon(!), served atop beans in a bolillo roll, topped with tomatoes, mustard, mayo, onions, and green chiles. That is, if you get it “con todo"—with everything. Some say these were invented in the city of Hermosillo, about a half-day’s drive south of Tucson, in the mid-20th century. They’re hard to find in most of the U.S. A tamarind soda washes it down nicely, and at “El Güero Canelo” you can get all the salsa, pico de gallo, roasted jalapeños, and grilled green onions you can eat to go with it! (Tacos and burros—not “burritos"—also are available, as well as “caramelos,” the Sonoran term for quesadillas with meat.) For more info: elguerocanelo.com

At Salt Water Farm, students return to the land—and the sea—to learn forage, fillet, and feast.

If you only have time to shop one place while in Cape Town, make it the Watershed market on the V&A Waterfront. A magnet for, well, virtually everything, the stalls and shops feature all the classic South African goods, from gorgeous green malachite bowls and bracelets to souvenirs made of springbok hide, recycled bottle caps, and even pressed protea flowers. There are also outposts of beloved local brands like Skoon (for sustainable beauty products), plus art (both affordable and aspirational), East African kitenge fabrics fashioned into simple Western styles, adorable baby clothes, and hand-painted leather clutches that are guaranteed to get compliments no matter where in the world you take them.

The Grand Central Oyster Bar celebrates its 100th anniversary this year as a New York institution. Located in the lower concourse of Grand Central, it serves over 25 varieties of oysters daily. There is a huge menu of American seafood—chowder, fried clams, lobster rolls, clams casino—whatever you are looking for, they will have it. The Oyster Bar is also famous for its architecture—the beautiful arched tile ceilings are the hallmark of famed Spanish architect Rafael Guastavino, who left his unique stamp across NYC. Take your pick from three different seating areas: a series of old-fashioned, U-shaped counters which seem to be popular with tourists and locals; the oyster bar, which would be perfect for singles or those dining in pairs; and the saloon-type restaurant in the back, popular with the business crowd. Wherever you are sitting, it will be bustling with activity. While there are several other oyster bars in the city, the Grand Central Oyster Bar offers a piece of New York history. It’s like stepping back in time, a retro celebration of old Americana that generations of locals, tourists and travelers have visited over the years. My suggestion is to stop in for fresh oysters and cold beer at the bar.