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Foodies (and those simply interested in local color and a good meal) should head to San Lorenzo and its covered Mercato Centrale. Florence’s main market for edibles is housed in a 19th-century glass-and-iron building. On the ground floor, delis, stands, and butcher counters sell a fantastic array of local fruit and vegetables, cheeses, dried porcini mushrooms, baked goods, balsamic vinegars, and olive oils plus fresh fish, poultry, and meat. Upstairs, a modern food hall has opened: Stalls sell prepared foods and meals for happy and immediate consumption at a central seating area.

Far and away Seattle‘s most iconic structure, this U.F.O saucer on a stick is an Atomic Age baby—it only dates back to the 1962 World’s Fair. A 41-second elevator still whisks guests to the observation deck, which really ladles on the natural beauty when the clouds lift and “the mountains are out.” The Needle underwent a glorious $100-million “space-lift” in 2018. Innovations include floor-to-ceiling glass walls with benches that angle backwards (designed for great selfie angles—seriously!). The landmark also added the world’s first and only revolving glass floor, spinning under the Atmos Wine Bar. A café still serves quick bites, but the full-service restaurant has yet to reopen in early 2019. Below sprawls the Seattle Center’s carnival rides, science exhibits, world-famous glass art garden and the MoPop, a superb rock and sci-fi museum that resembles Jimi Hendrix’s smashed guitar when viewed from above

For the location of their first independent hotel, Atelier Ace (the creative arm behind the buzzy Ace Hotel Group) chose Panama City’s historic Casco Viejo, a once gang-ridden neighborhood now teeming with trendy restaurants, cafes, and wine bars in 16th- and 17th-century buildings. The American Trade Hotel occupies a stately property on Plaza Tómas Herrera, complete with 50 minimal-chic rooms and suites outfitted in Frette linens and custom, reclaimed-wood furnishings. Plush “Jardin” suites open onto a private garden courtyard, while others feature vaulted ceilings or views of the Gulf of Panama. On-site dining and drinking options abound, ranging from Café Unido for pour-over coffee made from Panama Geisha beans, to a jazz club created by Grammy-winning Panamanian jazz pianist and composer Danilo Perez.

Immediately adjacent to Loews Regency, the Sant Ambroeus Coffee Bar is one of the latest outposts of this popular group of New York, by way of Milan, restaurants. The original Milan restaurant opened in 1936, and there are now three others in Manhattan, as well as one in Southampton. The Park Avenue coffee bar has an Italian art deco decor, bringing a little bit of Milan’s style to the neighborhood, and several outdoor tables. Choose from a panini or one of Sant Ambroeus’s famous pastries.

Praised by everyone from the James Beard Foundation to Anthony Bourdain to Esquire to RateBeer.com for its massive selection and delicious eats, the Porter Beer Bar is one place well worth a stop. The Porter opened in 2008 in a narrow space in Little Five Points. It boasts 44 beers on draft and over 700 bottled. The food is made by an award-winning chef, serving up upscale bar food. The portions are massive, particularly buffalo shrimp po boy with herb fries. It can rarely be said that everything on a menu is good, but the Porter may just be an exception.

When you live in Miami, you crave more than the glittery neon of South Beach. In Wynwood, the areas most up-and-coming hub for art and nightlife, Gramps appears like a grungy truck stop on the orange dive exterior. Inside, the bar includes live music, stand-up comedy and games. The bar serves creative speciality cocktails with flavorful, fresh ingredients. Outside, there’s an expansive patio with graffiti, art, picnic tables and live sports broadcasts projected on the buildings exterior. The vibe here is totally relaxed and vibrant. The crowd consists of hipsters, artists and fashionable hippies.

Few places give better city views than rooftop bars. Six Feet Under, with locations next to Oakland Cemetery and in the Westside, both have a rooftop bar. The original Six Feet Under in Grant Park was named for its proximity to the city’s most famous cemetery and is known for its raw bar, fried seafood, and beer selection. Grab a seat on the rooftop early, as it gets crowded quickly.

Located in the wine-growing region of Oberbergen, this long-running restaurant earned a Michelin star way back in 1969—and has held firmly to it ever since. Owner Fritz Keller’s family has been producing and importing wines since the 19th century, and Schwarzer Adler is very much an oenophile’s spot, with a list that spans around 2,500 labels (including bottles from the Keller estate as well as other European wines, with a focus on Burgundy and Bordeaux). The Francophile menu—designed by long-standing chef Anibal Strubinger (who continues to support the team alongside new head chef Christian Baur)—perfectly complements the wines, with dishes like liver pâté, lobster, and poulet Bresse with black truffles. Adding to the food’s classic feel, the dining rooms are old-fashioned and intimate, with wood-paneled walls and vintage tiled stoves. Service is friendly and efficient, and there’s a small terrace for dining outdoors in nice weather.

Six Senses is known for top-tier, sustainability-focused resorts in far-flung locales like the Maldives but, in 2015, the Bangkok-based hospitality brand opened its first European resort in Portugal’s wine-producing Douro Valley. Housed in a 19th-century manor house with a terracotta-tiled roof, the property features a contemporary interior, outfitted in shades of muted gold, gray, and white. Set high on a hill, the 57 rooms, suites, and villas offer stunning views of rolling vineyards, lush forests, or the property’s courtyard.

For what are undoubtedly the best vistas, choose one of the fifth-floor Quinta Panorama Suites, each with floor-to-ceiling windows that look straight onto the meandering Douro River. A wine cellar and library showcase the best of the region’s vintages, while three restaurants make use of vegetables and herbs harvested from the resort’s own organic garden. Apropos of a spa in wine country, nail treatments come with wine and cheese tastings, and scrubs and masks are individually blended with grapes, salts, herbs, and other natural ingredients.

Broadway Oyster Bar wears many hats. First and foremost, it’s an oyster bar, serving bivalves in a variety of fashions, from raw and char-grilled to fried and Rockefeller style. It’s also a solid bar, where a lot of folks come to party both before and after Cardinals games. Finally, it’s one of the finest music venues in St. Louis—or at least the most fun—with live shows twice a day, save for Fridays when one act plays the whole night. Expect local and national bands, plus a lot of New Orleans artists, playing anything from bluegrass to rock and reggae. Between all the eating, drinking, and music, take some time to learn the history of BOB. It’s housed in a building from the 1840s—one of the oldest in the city that’s still in use—that has served as a boardinghouse, Chinese laundry, record store, and bordello over the years. Naturally, it’s said to be haunted.

You might expect to find a man with a last name like “Visscher” (fisherman in Dutch) to be behind a restaurant specializing in fresh seafood. But Fons de Visscher took it a step further. Three years after his successful launch of The Seafood Bar on Baerlestraat in the Museum Quarter, the former fishmonger opened a second, larger location on the lively Spui in central Amsterdam.

Since March 2015, seafood lovers have been satisfying their appetites for something fishy at the sleek bistro serving top-quality oysters, mussels, king crab, prawns and lobster. Such classics as fish and chips, bouillabaisse, steamed mussels, and a Fruits de Mer platter bait repeat customers for lunch and dinner.

With its breezy interior, white tiles, exposed brick walls, and hanging white lamps, The Seafood Bar Spui feels like it could be by the ocean. A street-level Oyster Bar whets guests’ appetites as they enter. A second level hosts a bar, while two rear spaces provide quieter enclaves for diners enjoying meals alongside displays of giant King Crab legs and glass-encased oysters, crabs, prawns and sardines. The restaurant adheres to sustainable seafood practices and prides itself on its preparation of fresh, organic and line-caught fish.

The Seafood Bar’s bright, bustling ambiance is hardly conducive to romance. But a wide selection of soups, salads and sandwiches starring creatures fresh from the sea makes up for a little distraction at this casual Nirvana for fish-lovers.

No visit to Ambergris Caye is complete without an afternoon at the Palapa Bar. Situated at the end of a dock surrounded by turquoise waters and cool breezes, Palapa Bar attracts a mix of locals, travelers, and some of the coolest bartenders on the island. On a warm day, eschew the barstools and opt instead to float in inner tubes beside the dock; you can even have cold buckets of Belize’s Belikin beers lowered down to you. In addition to beer and standard cocktails, fun creations like Scotty’s Palapa Punch (three different types of rum, triple sec, mango, pineapple, and a squeeze of lime) offer some island-inspired refreshment. Up in the palapa, recommended items from the menu include sausage dip, pulled pork sandwiches, and the immense half-pound burger. Palapa Bar is 1.5 miles north of town and easily reached by golf cart, taxi, bicycle, or water taxi, which drops you right off at the dock.

This honky-tonk-inspired bar has a hometown feel and a country vibe, and has great local beers on tap—like Grand Cayman’s classic premium lagers, the CayBrew and Caylight. Don’t miss out on the Thursday night Rock & Roll Bingo: It can get rowdy and is a lot of fun. Lone Star Bar and Grill is well known for its BBQ, including Texas-style ribs as well as barbecue chicken and burgers. When you get the munchies after a few beers it’s a nice break from the gamut of seafood offered at other establishments.

There are certain touristy things that one must do while traveling. And some places are so great that even locals flock to them despite the fact that they’re heavily trodden. The Opera Bar at the Sydney Opera House is one of those places. There really isn’t a good reason not to hit happy hour at the Opera Bar. The drinks are reasonably priced, and the selection is impeccable. There is live music every night of the week and the vistas offered by the bar are some of the best in all of Sydney. Transportation options to and from the Opera House are plentiful not to mention that site-seeing and drinking almost always go good together.

Txakoli. It’s not as hard to say as it looks, and it’s really easy to drink. This slightly fizzy white wine is unique to the Basque Country and is made (officially, at least) from the local Hondarribi varietal. Many of the bodegas in the D.O. Getariako are open for public visits, and some of them will even prepare you a mini feast to accompany the wine while you feast your eyes on the gorgeous scenery.