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Little-known fact: New Orleans was the first place in North America to license pharmacists (starting in 1769, when the city was still under Spanish rule). After Louisiana became a territory, the U.S. governor extended the requirement, also decreeing that pharmacists take a three-hour licensing exam in order to practice. And no wonder illness got such attention—the city was arguably the least healthy place to live on the continent; it was riddled with yellow fever, malaria, and dysentery. This dark but fascinating history is explored in this atmospheric 1822 town house, which was once the home and shop of Louis J. Dufilho, the first licensed pharmacist in the city—and hence in the country. Exhibits include apothecary jars, tools of the trade, and leeches. (Yes. Leeches.)

This perennially popular bakery and sandwich spot can feel somewhat out of place. With its cozy atmosphere in a plant-filled space, and its menu of warm panini, delicious sandwiches on artisanal breads, generous salads, and perfectly executed pastries, it is the sort of restaurant you’d expect to find in one of Montréal’s cooler neighborhoods. Instead, it’s in the heart of Old Montréal. That is a definite plus for travelers visiting the city’s historic sights. It also means, however, that there is a lunch-hour rush when nearby office workers vie for tables. If you can plan on an early or late lunch—you’re on vacation, after all—you can avoid the worst of the crowd. Olive et Gourmando is open from 9 a.m. to 5 p.m., so if you are looking for a place for dinner, the same owners are behind the new Foxy (in the Griffintown neighborhood), which is quickly proving as popular as their first restaurant.

One of Dalmatia’s most underrated cities, Šibenik is finally being recognized as an exciting coastal destination. Its medieval heart is a stone maze of steep alleyways dotted with charming squares and hidden cul-de-sacs, not to mention a pretty harbor and a seafront promenade lined with cafés. Crowning it all is the Cathedral of St. James, an architectural masterpiece incorporating style elements of both the Gothic and the Renaissance. The cathedral is said to be the world’s largest church built entirely of stone—most of which was quarried in the nearby Adriatic islands. Of particular note in this UNESCO World Heritage site: the frieze of 71 heads on the cathedral’s outer wall, which depicts 15th-century citizens of Šibenik with many different moods and personalities.

Expat owned and run, this spot brings California-style burritos to Mexico. The tiny outdoor restaurant—featuring only three long tables—routinely fills with an eclectic mix of locals, foreign residents, and tourists in search of a casual spot for laid-back socializing. The hole-in-the-wall chic surfer vibe pairs well with made-to-order burritos and tacos with several kinds of seafood and tortillas; you’ll also find umbrella drinks, traditional Mexican micheladas (beers served with ingredients like lime juice, chili powder, and Worcestershire sauce), burgers, and ceviches. Best of all, it’s open round the clock, making it an easy option for wee-hour snacking when Party Center clubs let out.

The country’s third-largest city, and the largest in central Vietnam, Da Nang has become one of the country’s key ports thanks to its location on both the coast and the Han River estuary. The city itself is a typical bustling Vietnamese metropolis with relentless scooter traffic, but a number of attractions make visiting worthwhile. The town’s Dragon Bridge opened in 2013, but what makes it special is that every weekend evening the steel-arch dragon that forms a part of the structure spits out real fire from its head (the bridge is closed to traffic at the time, allowing crowds to see the spectacle up close). The Marble Mountains—five hills that seem to have just sprouted up in the south of the city—are an arresting sight. The Son Tra peninsula, with a marquee attraction known as Monkey Mountain, offers some good hiking and excellent sea and city views; you’ll also find the 220-feet-tall, gleaming-white Goddess of Mercy statue here. The sandy stretch east of the city center (given the nickname China Beach by American soldiers during the war) is crowded with restaurants, bars, and some seaside hotels.

Chef/owner Aaron Silverman’s farmhouse restaurant, in the heart of Barracks Row, serves creative (and Michelin-starred) cooking inspired by his travels and culinary training in the American South, Mexico, the Mediterranean, and Southeast Asia. Pork sausage and lychee salad is a menu mainstay; most other dishes are rotated out frequently to make way for “new stuff,” anything from grilled cucumber with coconut and anchovy to jumbo lump crab with squash blossom. Groups of six to 12 can make online reservations, all others should be prepared to wait a while. Line up before the 5 p.m. opening time to snag a seat at the counter facing the open kitchen and wood-burning stove.

A modest, friendly family establishment (serving since 1963) where locals and visitors-in-the-know visit for flavorful James Beard award-winning New Mexican cuisine including carne adovada with warm, marinated roast cubed pork in a brick red chile sauce.

The vast wilderness of Glacier 3000 continues to beguile visitors year after year. While you can ski here, most take a snow cat or dog sled across the plateau, or hike to the precipices and look down on the surrounding area. Glacier 3000 is also home to the world’s highest rollercoaster, which hurtles around corners and dips drastically, imitating the sensation of freefalling toward the ice at heart-racing speeds.

The lion cub was licking my hand as if he were a puppy!

Haleakala, a huge and dormant shield volcano, forms more than 75 percent of Maui’s landmass. As such, it pretty much demands you ascend its slopes and peer into its crater—the island’s very soul. Legend claims the demigod Maui snared the sun here, freeing it only after it swore to inch more slowly across the sky.

The 38-mile, two-and-a-half-hour drive up Haleakala climbs from sea level to 10,023 feet through several different ecological zones. One of the most popular ways to experience the volcano remains cycling down from the summit at sunrise. Do it yourself if you’re confident, or join a guided tour (Skyline Eco-Adventures offers one that includes a zip-line ride). Once you’ve mastered the motion—and the 21 switchbacks along the road—effortless downhill freewheeling rewards you with unsurpassed views of the island. If you’d rather savor the vistas from a lofty perch, drive to the top for the sunset or book an overnight at one of the park’s wilderness cabins, accessible only by hiking trail.

Bangkok’s most iconic site is a massive palace complex that served as the royal residence until 1925. Of its many buildings, the one with the most architectural interest is Chakri Mahaprasat. It was designed in 1882 by British architects, in a style that could be described as traditional Thai meets Italian Renaissance. Nearby is the 1784 Wat Phra Kaeo, or Temple of the Emerald Buddha, Thailand’s most sacred Buddhist place of worship. Go inside to see the Emerald Buddha, carved not of emerald but of semiprecious green stone, robed in gold and just 66 centimeters (26 inches) high.

Board an elegant 1930s Venetian taxi boat for the most romantic Seine River tour on the waters of Paris. Champagne is chilling in the ice bucket and a few snacks are served as well, but the real show is life on the river, up-close and more personal than you could ever get on the larger boat tours. Wave to picnickers on the berges, spy on lovers canoodling under the bridges, and peek into barge homes from your 30-foot wood and chrome beauty. Take the evening tour, and you’ll witness the Eiffel Tower sparkling every hour on the hour.

This tiny island is north of Isla Mujeres and Cancun and is only 26 miles long and offers visitors in search of a “Robinson Crusoe” experience the perfect escape. Long, sweeping beaches beckon with water sports, snorkeling, sport fishing, and total R&R. A shallow lagoon gives sanctuary to thousands of flamingos, pelicans and other exotic birds and creatures, allowing visitors the perfect spot in which to commune with nature. Several good restaurants and hotels are available and tours to area attractions can be arranged by ferry and small plane. Getting around the island is via bicycle or golf cart.

Upon first entering the famed blue doors of Per Se, located inside the Time Warner Center overlooking Central Park, the dining room has the air of a wake, filled stiff collars and hushed tones. But no matter the attitude, the fact is that everyone in the dining room waited at least a month for this moment. At Per Se, you can only make a reservation one month in advance (maximum), and, if you procrastinate a day or two (say 28 or days or less before your desired date) you’ve likely missed your chance. (Do take note that you cannot cancel a reservation within seven days without being charged $175 per seat reserved.) This is an experience that will last up to four hours, where you are served from five to nine courses (depending on the menu you select), with many surprises in between, including personalized menus with your name and event (if you’re celebrating anything) on each. Now, if you’re still interested and not frightened away by the potential cost, then you’re in for an amazing afternoon or evening of small plates with the most amazing tastes you’ll ever come across. Do not be deterred by the portion sizes as you will most certainly leave full. It might even be best if you arrive on the borderline of famished, as it is a crime to leave anything behind.

Just as Rome has the Colosseum and Paris the Eiffel Tower, so Switzerland has the Matterhorn. Located above Zermatt, this 48,195-foot wonder attracts hordes of visitors, eager to see the morning sunlight beam off its four faces, ski its neighboring mountains, or even attempt to climb the beast itself. The Matterhorn, however, is not for the faint-hearted and has claimed the lives of more than 500 people since it was first scaled in 1865—an average of 12 per year. It’s also been replicated at Disneyland in California as a rollercoaster.