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Little-known fact: New Orleans was the first place in North America to license pharmacists (starting in 1769, when the city was still under Spanish rule). After Louisiana became a territory, the U.S. governor extended the requirement, also decreeing that pharmacists take a three-hour licensing exam in order to practice. And no wonder illness got such attention—the city was arguably the least healthy place to live on the continent; it was riddled with yellow fever, malaria, and dysentery. This dark but fascinating history is explored in this atmospheric 1822 town house, which was once the home and shop of Louis J. Dufilho, the first licensed pharmacist in the city—and hence in the country. Exhibits include apothecary jars, tools of the trade, and leeches. (Yes. Leeches.)

Dana Biosphere Reserve is the largest nature reserve in Jordan. For hikers and trekkers, it’s one of Jordan’s top places to get out into the wilderness, but even the less adventurous will enjoy a stop here simply to enjoy the tranquillity of Dana village, with its majestic views over the tumbling hills below. The reserve is dominated by enormous sandstone cliffs that guard the valley, creating a series of microclimates and ecosystems that house nearly 200 species of birds and most of Jordan’s mammals. Sightings of ibex, gazelles, and even wolves are not uncommon. At the entrance to the reserve in Dana village, you’ll find an excellent visitor center run by the Royal Society for the Conservation of Nature, which can recommend park guides. For a different way to experience the reserve, consider the five-day hike from Dana to Petra—deemed one of the greatest treks in the Middle East. It’s particularly pretty early in the year, when the route is laid with spring flowers.

Towering palms and a true Scottsdale vibe greet guests of the Westin Kierland Resort & Spa, located in northern Scottsdale. Families will love features like the Adventure Water Park, which has a lazy river perfect for floating on a sunny day, a water slide, and even a spot to do some desert-style surfing on the FlowRider. A kid-friendly light show takes place seasonally at night, and the projection onto the hotel makes the building look like it has come to life. For the grown-ups, the property is an even better place to play. By day, go for a round of golf on the award-winning links, lounge at the adults-only pool, or enjoy a massage at Agave, the Arizona Spa (the namesake plant, native to the area, is used in many of the treatments). By night, choose from four on-site dining options—not including cozy in-room bites. Be sure to make a reservation at Deseo, where Chef de Cuisine Derek Biazo serves up delicious contemporary Latin American small plates (try the hamachi ceviche with truffle ponzu sauce, and definitely don’t skip dessert or the exceptional wine list). Tipplers will also appreciate the open-nightly Scotch Library, which boasts more than 300 labels and kilt-clad Scotch Ambassadors who can guide you through a tasting. The Scotch Library is one of the hotel’s many tributes to the area’s history and culture. Scottish immigrants played a role in establishing the early economy of Arizona, and homage to that heritage is evident not only in the Scotch Library but also in the sunset bagpipe shows and the offering for golfers to play Scottish-themed golf. Other nods to local culture include the rehabilitated desert reptiles in the lobby (don’t worry, they’re enclosed) and room decor highlighting important personalities and moments from Arizona’s history like female pilot Ruth Reinhold, who taught pilots in World War II and eventually became Arizona Senator Barry Goldwater’s personal pilot.

For evidence of the “everything is bigger in Texas” trope, look no further than this urban resort, which—with 1,606 Asian-accented guest rooms and suites spread out over 45 acres—is one of the largest in the south. Its location in the Design District, not far from the Dallas Convention Center and the office towers of downtown, makes it popular with the business-meeting crowd (as does the 600,000 square feet of on-site event space), but there’s plenty to tempt leisure travelers, too. Paired with an outdoor sculpture garden, more than 1,000 international works displayed throughout the property make up one of the biggest hotel art collections in the world. Guests can dine on everything from steak and seafood to pizzas, salads, and grab-and-go snacks at the eight restaurants and bars, or make a night of it with specialty cocktails and fine wines. They can also relax with treatments at the VSpa, or work off indulgences at the whopping 80,000-square-foot Verandah Club & Fitness, equipped with indoor and outdoor pools; basketball, squash, and racquetball courts; a cross-training and boxing gym; and more. In the summer, the sprawling Jadewaters pool complex—with lazy river, swim-up bar, 180-foot water slide, and kids’ activities—is as close as you can get to a water park in the heart of the city.

Situated closer to Cambodia than Vietnam in the Gulf of Thailand, Phu Quoc has arguably the best beaches in the country. An international airport opened in 2012, raising the island’s profile and bringing in droves of visitors. Despite this, the island retains a laid-back, underdeveloped charm, and its coast is still dotted with small fishing villages with brightly painted boats. The interior of the island includes plenty of forest, while some of the land is earmarked for growing black pepper—pepper from here is famous throughout Vietnam. The best beach lies to the west of the town of Phu Quoc; it’s a 13-mile long straight stretch with golden sands, coconut palms, and clear turquoise waters. The An Thoi Islands, south of Phu Quoc but still part of its marine park, offer excellent snorkeling and diving during the dry season from December through May.

Multnomah Falls is a gorgeous sight located about 45 minutes by car outside of Portland, Oregon, on the Columbia River Gorge. Several hikes of differing degrees of difficulty offer vantage points to view the falls. The sound of the rushing water is a soothing composition from Mother Nature.

Originally built to serve the area’s fish canneries, the Historic Requa Inn, at the base of the Klamath River, is one of the few small hotels right near Redwood National and State Parks. You can come for dinner even if you’re not staying at the inn, which is run by a local family. They offer a prix fixe menu Wednesdays through Sundays from April 1 to October 31. The only seating is at 7 p.m., and what you get is a communal, family-style meal: A small group of people sits around a table and shares a selection of seasonal Californian dishes, which are all crafted using ingredients sourced from a nearby organic farm. (Think of it as having dinner with your family, just tastier.) Make a reservation ahead of time, since spots are limited. Visitors can also pick up a picnic lunch here if they order one 24 hours in advance. Although an old establishment, it’s well-kept; guests will find there is no TV or phone in their room, which provides the perfect excuse to sit outside and enjoy the water going by.

Tempt fate at the Monkey Paw’s Book-O-Matic machine, where for the price of a toonie you’ll be delivered an archaic tome in the vein of Elementary Arabic, Vol. 3. I’ll let you know how my studying gets on. The Monkey’s Paw is an eclectic vintage bookstore on Dundas with a collection of unique books, vintage maps, and bugs preserved in Lucite.

The Riviera Maya’s most beautifully styled adventure park begins with a reception area inside a natural cave. Tours here include Latin America’s highest zip lines over the tropical forest, amphibious vehicles you drive through caves and jungles, and swimming and rafting through underground rivers. Though Xplor is a family-friendly attraction, it may be better suited to teens and adults because of the physical activity required. If you don’t have all day, book Xplor Fuego, the nighttime admission: Temperatures are cooler, torchlight adds an exotic touch, and you soar over the trees by moonlight.

Originally laid out during Spanish rule, the Alameda Central was Mexico City’s first municipal park, at one time reserved for the elite. Today it’s a well-manicured garden for all, especially popular with working-class crowds on Sundays. Its willow-lined lanes lead to old-fashioned statuary, fountains, and a gazebo (where something’s always going on), as well as a rotating calendar of contemporary sculpture exhibitions. On the park’s western edge and occupying a beautifully restored art deco structure, the shopping and design center known as Barrio Alameda houses edgy boutiques, a chic guesthouse, and trendy restaurants whose outdoor seating is a people-watcher’s delight. Duck in for a glimpse of how the city center continues along its gentrifying course.

In recent years, this pretty neighborhood, located just five minutes north of downtown Orlando, has become a dining, shopping, and entertainment destination in its own right. Edgewater Drive is lined with restaurants, shops, and offices, while the surrounding residential areas feature historic bungalows, Craftsman-style homes, brick streets, and lakefront views. Favorite eateries in the neighborhood include Jade Sushi & New Asian and K Restaurant, which is nestled in a cute old house. While there isn’t a college nearby, the area gets its moniker from streets named after famed universities like Princeton, Dartmouth, and Harvard.

Atop Cap Diamant (Cape Diamond), at the city’s highest point, the Citadelle overlooks Old Québec, the St. Lawrence River, and the Plains of Abraham. There have been defensive structures here as early as the French period—in fact, the location of Québec City was chosen because Samuel de Champlain saw the strategic advantages that Cap Diamant offered. The fortifications you see today, however, date to the 19th century: They were built after a failed attempt by Americans to conquer Québec City during the War of 1812. Students of World War II history may be familiar with the Citadelle as the site of the Québec Conferences, when Winston Churchill, Franklin Delano Roosevelt, and Canada‘s prime minister, William Lyon Mackenzie King, met to plan their countries’ strategies during the war. The Citadelle is still an active military base; the museum inside is devoted to the 22nd Regiment, which makes its headquarters here.

This dramatic two-tier waterfall, whose name translates as “Golden Falls,” a reference to the shimmering mist that sometimes appears around the falls, is one of Iceland’s most famous—which is saying something in a country abundant with waterfalls. Saved from oblivion during the 1920s (foreign investors wanted to dam the falls to create hydropower), the waterfall lies in a canyon on the Hvítá river and is backed by scenic snowcapped peaks. It’s possible to follow the falls as they flow downstream through the canyon, either via a walking trail or on a rafting trip, though it’s worth noting that the paths are wet and can be slippery. The visitor center has a canteen that serves up surprisingly tasty local dishes like lamb soup; there are also a gift shop and a local exhibition centered around traditional life in the area.

Since everything seems bigger in Texas, it’s no surprise that the Texas State Capitol holds the title for largest state capitol building in the union (360,000 square feet of floor space in the main building!). The building is also quite beautiful and houses some historical paintings. The inside of the capitol dome, with a lone star at the apex, is an impressive sight. Stroll the grounds to see fountains, old trees, and sculptures of historical Texas figures. The capitol grounds also offer a great view of downtown to the south and the University of Texas to the north. The Texas landmark is definitely worth a visit on a trip to Austin.