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This 19th-century complex, originally built as a hospital for the disadvantaged, is host to an impressive display of modern art, most notably a series of frescoes by famous Mexican muralist Jose Clemente Orozco. The collection includes one of his most well-known murals, El Hombre de Fuego, which earned its building the nickname “the Sistine Chapel of the Americas.” A UNESCO World Heritage Site, Hospicio Cabañas is a perfect example of Guadalajara’s ability to embrace its history and its future, combining 1790s architecture, 1930s murals, and, finally, a space for rotating exhibitions of contemporary art.

Having functioned as an orphanage, an insane asylum, and a military barracks in the past, Hospicio Cabañas also has a spooky side. There are several ghost stories about the space, including a legend about a clock that stopped whenever a child died in the orphanage.

With its waterfront location across from the San Francisco Ferry Building on the edge of downtown, the 1 Hotel is an ideal launchpad to explore San Francisco. Rooms have expansive views of the Bay or the city, and travelers can step out onto the Embarcadero for a morning run, to browse at one of three weekly farmers’ markets at the Ferry Building.

The luxury hotel upholds a commitment to environmentalism, using local and reclaimed materials for the biophilic interior design, sustainability sourced bedding, and providing filtered water taps instead of single use water bottles. Rooms are equipped with soft cotton robes, slippers, and yoga mats to help turn a stay into a relaxing, wellness-minded retreat.

On the first floor, the bar and restaurant, Terrene is a lovely place to swing by for a drink or meal—whether you’re a guest or not. If the weather is nice, don’t miss the chance to enjoy a cocktail on their expansive outdoor patio (complete with space heaters) with great views of the Bay Bridge. If you’re looking for something more substantial, they have an excellent selection of fresh, Mediterranean-inspired dishes, like roasted carrots with a feta dip and refreshing tuna tartare.

Pets are welcome and there’s also a rooftop spa on site, complete with stone tubs and scenic views.

Frank Altamura took his time renovating the old Italian grocery store — where he remembers shopping as a child — at the north end of Yountville. His dream was to turn the partly dilapidated building into a casual restaurant with great pizza and Napa Valley wine where locals would love to eat. His dream came to fruition when Ciccio opened its doors in 2013. The menu is simple, straightforward and ever-changing based on what Altamura is bringing in from his Napa ranch, where he also grows Cabernet Sauvignon, Nebbiolo, Sangiovese and Negroamaro for his eponymous wine. Chef Polly Lappetito (former Executive Chef at The Culinary Institute of America) traveled far and wide in search of the perfect pizza crust, but her’s is in a category all its own — prepared in a hand-tiled, wood-burning pizza oven imported from Italy.

If you haven’t before seen 1.5 million bats flying out for their nightly feeding at once, now’s your chance. The largest urban bat colony in North America, Austin‘s Congress Avenue Bridge is the home to hundreds of thousands of Mexican free-tail bats from mid-March to mid-October. Every night around sunset, the colony emerges like a black cloud from the crevices underneath the bridge, heading out to feed on millions of bugs around Austin. A beloved tourist attraction since the bats made their home in the bridge during the 1980 renovations, crowds pack the east-facing sidewalk and the park to the south side of the river to watch the nightly exodus. Want more details? Call the Bat Hotline at 416-5700, extension 3636, for exact exodus times. Christian Bale may or may not answer.

Built from 1892 to 1894, this uniquely intact Victorian mansion was the home of German-American philanthropist and beer magnate Christian Heurich. Considered the world’s oldest brewmaster, he ran the Christian Heurich Brewery on the site where the Kennedy Center now stands—until his death in 1945 at the age of 102. At this museum, visitors can learn the story of one of D.C.'s most successful entrepreneurs and his family, his influence on America’s brewing industry, and the construction of his 31-room mansion. As D.C.'s first fireproof home (he had a fear of fire), it is replete with hand-carved wood, 15 fireplaces with individually carved mantles, hand-painted ceiling canvases, luxurious furnished rooms, original Heurich family heirlooms, a bierstube (“beer room”), elevator shaft, and gas and electric lighting fixtures.

This archipelago off the coast of La Paz (which takes the name of the main island) is a protected UNESCO Biosphere Reserve. While the islands are uninhabited by humans save for a small fishing camp made of temporary structures, they’re home to a great variety of flora and fauna. In addition to dolphins, frigate birds, and ring-tailed cats, you’ll find the only known black jackrabbit population in the world. Celebrated eco-friendly activities company Cabo Expeditions leads daylong archipelago tours that include exploring the mesmerizing volcanic landscape, a ceviche lunch, and an opportunity to swim on Ensenada Grande Beach—often cited as one of the world’s most beautiful—plus guided snorkeling with the incredibly playful pups at the Los Islotes sea lion colony.

Just a few hours north of Lima, you can visit the sacred city of Caral-Supe, an ancient archaeological site that marks the earliest known instance of complex civilization in the Americas. The ruins at this UNESCO World Heritage Site date to approximately 3,000 B.C., and they are remarkably well-preserved for their age. Caral was almost certainly developed by a highly religious society, as evidenced by the stone monuments and pyramids, the the sunken circular courts, and the remnants of homes that likely belonged to the city’s elite. The physical setting is as striking as the cultural setting: the 626-hectare city is perched on a dry desert terrace overlooking the lush Supe River Valley, framed by mountains, close to the sky. You can hire a tour or take a car to visit this site on a day trip from Lima.

Under the eave, a monkey supports the weight of a temple roof on Ganghwa Island, in the Han river estuary, northwest of Seoul, a stone’s throw from North Korea... On one of my teen-age visits to Korea, an uncle took us to spend the day here, an island dotted with prehistoric dolmens, Buddhist temples, and 19th-century fortresses that kept out the French and the Americans in the last days before the ‘Hermit Kingdom’ finally opened up to the West. Jeondeung-sa temple, where I took this photo, has been a Buddhist sanctuary since the late 7th century. And here, I first tasted ‘dol-sot-bi-bim-bap,’ the quintessential Korean hot-pot rice dish, served sizzling in a stone bowl.

Who hasn’t daydreamed about being an astronaut at least once? Thankfully, Space Center Houston makes it easy to learn about the great beyond. It’s the area’s No. 1 attraction for international visitors and the first Smithsonian Affiliate in the greater Houston area. The center features more than 400 space artifacts and several exhibits related to the past, present, and future of America’s human spaceflight program. It’s also home to the world’s largest collection of moon rocks and lunar samples for public view, and offers guests the opportunity to go behind the scenes to see NASA’s Johnson Space Center.

Wonderful catamarans that you can rent right off the beach.

Casa Morada’s dressed-down modern coastal style reflects a love of the ocean, island plant life, and luxurious comforts. The 16-suite boutique hotel—once a 1950s roadside motel—underwent an extensive renovation in the early 2000s that transformed it into one of the Key’s sexiest spots. The Raymond Jungles–designed gardens are lush, the outdoors showers and jacuzzis are impossibly romantic, and the resort’s private island features a freshwater pool. If you can rouse yourself for anything other than relaxing by the water, try your hand at a game of bocce, snorkle around the only living coral reef in North America, go on a sunset sail, or charter a boat tour with local resident Captain Bill to visit the Mangrove Islands or Three Sisters Bird Rookery. Pro Tip: Morning yoga classes are offered every Wednesday, Saturday, and Sunday at 9, but guests can book a private session anytime.

If you love the top fashion brands but your budget doesn’t, visit one of the many Dod stores in Brussels. These shops carry fashion brands from around North America and Europe and range from Valentino ball gowns to Esprit t-shirts. The fashions are end of line clearance items for 30-75% off the regular ticket price. You can find some great deals on beautiful garments. Dod has separate stores for men’s, women’s and children’s clothing, as well as shoes, luggage and handbags, sporting goods and household items. There are stores scattered around Brussels but my favourite is the original Woman’s Dod on Chaussée de Louvain. It’s 5 levels of bargain goodness with a whole floor of shoes in the basement. Best of all, prices are marked down even more during the bi-annual sales in August and January; just be prepared to stand in long lines at the registers.

Hello, rooftop pool! Leave it to Chicagoans to remain optimistic that summer will be amazing, even if winter lasts well into May. The rooftop pool (open to restaurant as well as hotel guests), occupies a prime spot on one corner of Six Points, that crazy intersection where three major shopping streets cross paths. That means the regulars are a mixed bag, but all come in for a good time, whether that means for brunch in the newly redesigned Café Robey street-level restaurant, to drink until dawn at the poolside Cabana Club bar, or to sneak up to its new sister, the Up Room, at the top of the deco tower.

If you associate the phrase all-inclusive with the bracelet-wearing, tropical drink–swilling masses, then Marquis Los Cabos will make you do a double take. The adults-only resort offers unique amenities—open-air yoga classes, a 13,000-square-foot spa, tequila tastings, salsa-dancing lessons—plus an architecturally stunning property with nary a cheesy palm-tree motif in sight. The views begin in the alfresco lobby, where a stone arch draws your attention to the horizon, and continue through two curvaceous infinity pools overlooking the Sea of Cortez. The 235 rooms, outfitted with marble baths and works by Latin American artists, are just as inspiring thanks to private balconies that offer views of whales and dolphins in the distance.

Chef/owner Aaron Silverman’s farmhouse restaurant, in the heart of Barracks Row, serves creative (and Michelin-starred) cooking inspired by his travels and culinary training in the American South, Mexico, the Mediterranean, and Southeast Asia. Pork sausage and lychee salad is a menu mainstay; most other dishes are rotated out frequently to make way for “new stuff,” anything from grilled cucumber with coconut and anchovy to jumbo lump crab with squash blossom. Groups of six to 12 can make online reservations, all others should be prepared to wait a while. Line up before the 5 p.m. opening time to snag a seat at the counter facing the open kitchen and wood-burning stove.