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We took a four night trip to the Peruvian jungle and the Macaws at this clay-lick were a highlight from the boat trip up the river.

As the name suggests, you can shout your order from the sidewalk and by the time you get to the counter, they’ve already served up your empanadas. Try the time-tested caldo mayo, a house-specialty beef broth that’s a perfect hangover remedy, especially with spicy salsa de ají, or hot pepper salsa, on top. Members of the Chilean judiciary are often seen here having a tintito, a dainty glass of red wine, before beginning the day’s proceedings. El Rapido opened in the thirties and has been operating ever since—don’t miss this quaint and tasty bit of history.

American sommelier Brian Patterson, his wife, Jenn, and their massive Leonberger-Retriever mix, Bear (the Beartender!) are the consummate hosts at Lisbon’s newest, most interesting, and surely smallest wine bar. Located on pretty Praça das Flores in Principe Real, Patterson curates his all-natural wine list with a laser focus on small producers from around Portugal. He sources his finds on reconnaissance drinking missions around the country, including some of Portugal’s more underdog wine regions. His updated-daily chalkboard menu includes a half dozen or so offerings by the glass (€3.50-7) along with two batch cocktails, as well as intriguing bar snacks to accompany (his hummus is destination-worthy in and of itself). The bar doubles as a bottle shop; rightfully so, there is only room at the bar for about 11 provided everyone is sucking in their wine guts. File under: Wine Revelation.

Built in 1703, Heidelberg’s oldest and most famous tavern has certainly had some illustrious patrons. Mark Twain, Marilyn Monroe, and John Wayne are just a few of the celebrities who drank and dined here—a fact that’s proven by the many photos of famous faces hanging on the walls. Notable clientele notwithstanding, Zum Roten Ochsen is all about simplicity. Still run by the same family that opened it hundreds of years ago, it serves rich local dishes, from goulash soup and bratwurst to Swabian Maultaschen (meat-filled ravioli) and Käsespätzle (cheese-covered noodles), as well as fresh herring, boiled beef, and several vegetarian options. Also on offer is a drinks menu heavy on regional wines and local Heidelberg beer, all of which are complemented by the restaurant’s old-fashioned interior, friendly service, and live piano player in the evenings.

Built between 1715 and 1718, the Baroque Karlsruhe Castle served as the residence of the electoral princes and grand dukes of Baden for more than two centuries. Designed by Jakob Friedrich von Batzendorf, the palace exterior is especially pleasing—not least because it was planned as the focal point of the city, with streets radiating out from all sides like wheel spokes (which in turn inspired Pierre L’Enfant, planner of Washington, D.C.). The castle also features picturesque pavilions and ornate wings, but for many the real highlight is the Baden State Museum inside. Opened in 1919 and generally regarded as the best in the region, the museum spans pre- and early history, with exhibits on the Ancient Greek and Roman eras as well as sculptures from the Middle Ages, a particularly celebrated art nouveau collection, and an impressive range of 17th-century Ottoman handicrafts.

A tribute to the zinfandel grape, which originated in Croatia, this restaurant and bar features a zin-centric wine list but also showcases regional favorites like Plavac and Dingač. Of its 100 wines, it offers about 30 by the glass, encouraging guests to taste their way through Croatia’s wine heritage. Pair your drinks with one of the restaurant’s three-tiered platters, which come loaded with Dalmatian bites, then settle in on the terrace for some live music. If you’re hungry for a full meal, opt instead for the five-course “Taste of Dalmatia” menu, which includes everything from seared Adriatic tuna and homemade oxtail ravioli to calamari stuffed with ricotta and sun-dried tomatoes. Come morning, Zinfandel also serves breakfast, which diners can pair with champagne or fig-flavored travarica, a local herb grappa.

The Church of the Nativity, a UNESCO World Heritage Site, is located south of Jerusalem in Bethlehem in the West Bank. It was originally commissioned by the Roman Emperor Constantine the Great in 327 and built over the cave where Jesus is said to have been born—the precise site is today marked by a silver star. Rebuilt by Justinian as a typical five-aisle basilica in 565, the Church of the Nativity has subsequently expanded into the sprawling complex it is today.

A stay at the adults-only Rachamankha feels like an extended visit to a supremely stylish friend’s home. Designed by interiors maven Rooj Changtrakul and renowned Thai architect Ongard Satrabhandu (who happens to be Changtrakul’s stepfather), the 24-room boutique hotel is inspired by 15th-century Lanna and features crisp white walls that offset Chinese antiques, vaulted wood ceilings, and colorful Thai silks. Serene courtyards give way to a library, an art gallery, and a poolside massage pavilion for low-key relaxation. Even the restaurant is primed to make you feel at home, serving regional comfort food like Burmese curry in an alfresco setting that reminds you why you booked here in the first place.

Hernán Cortés built a summer home here on top of the ruins of a pyramid. Over the next few centuries, Mexico City‘s political and economic elite and movie stars--and even the Shah of Iran--took up residence in this town. Cuernavaca--with its stately mansions and haciendas and blooming gardens--became known as Mexico City’s more glamorous and beautiful sister. Nowadays, an ever-increasing population means Cuernavaca has lost some of the mystique from its heyday, but its lovely gardens and Spring-like climate (and the fact that it is only an hour south of Mexico City) still make it a perfect getaway from that bustling megalopolis. Be sure to check out the Palacio de Cortés and Jardin Borda while you’re there. The former is Cortés’ old digs, and it now houses the Museo Regional Cuauhnáhuac, which, over two floors covers Mexican history from pre-Columbian times to present. The latter is a grand Versailles-inspired mansion and garden which will give you a wonderful view into how Mexico’s aristocracy lived in the 18th century.

Washington is famous for its apples, and fall is the best time of year to try our crisp, juicy fruit. The most coveted breed is Honeycrisp, prized for its extremely crunchy and crisp texture and lightly sweet flavor. Cameo is a pretty, tiger-striped fruit with a good crunch, discovered as a chance seedling in a Washington orchard. Other varieties you’ll find in local stores include Pink Lady (a sweet-tart, pink and green apple), SweeTango (a hybrid offshoot of Honeycrisp), Ambrosia (a crunchy, very sweet apple with champagne-like flavors and white flesh), and Jazz (a sweet red-and-gold apple). If you venture out to rural areas or fruit-orchard regions like Wenatchee, you’ll find fruit stands with these apples and many more, plus jugs of cloudy, freshly made cider that’s nothing like the store-bought version. And if our apples aren’t sweet enough for you on their own, there’s always the local Aplets and Cotlets fruit jelly candy, locally produced in Cashmere.

The Maremma region of southern Tuscany, about an hour south of Siena, is an area of olive groves, wooded valleys, and ancient legends. One such tale, dating from the days of the Etruscans and Romans, chronicles an epic battle in which Jupiter threw lightning bolts at Saturn—and missed. As the story goes, when the bolts landed on the ground, they formed the bubbling hot springs now known as the Terme di Saturnia. Full of therapeutic minerals, the hot springs feed a variety of pools throughout the valley that have warmed and healed centuries of bathers. Today, you can soak up the goodness at the luxury Terme di Saturnia Hotel & Spa, which offers therapies performed with the waters, or at a free public bathing spot. To find the main one, head down a dirt path just outside of town, past a parking lot and changing area, until you spy a waterfall feeding a series of natural pools, each turned white by the mineral-rich water.

Crupet is a member of the organization Les Plus Beaux Villages de Wallonie (The Most Beautiful Villages in Wallonia). It is a very small village with gorgeous stone houses decorated with many different types of flowers. Most of the houses date from the 17th, 18th and 19th century. The highlights of the village are the Crupet Chateau—a medieval farm-chateau situated below the village center, dating from the 13th century, and the Grotto of St Anthony of Padua. The grotto was designed by the local curate and inaugurated on the 12th July 1903. It features 22 religious-themed statues. Many of them depict scenes from the life of St. Anthony of Padua. The Ardennes region is an undiscovered Belgian treasure. There are many more charming little villages like this one. They look like time did not pass over them. When you enter a bakery people treat you like one of their own. Go and discover this wonderful part of Belgium. For full size photos see www.facebook.com/adisphotopage and www.lifeinasuitcase.com

There are few places where you can better learn about the beauty and complexity of desert ecology than the Desert Botanical Garden, not far from downtown Phoenix. Check out the Desert Discovery Loop Trail for a look at local flora, go for a flashlight tour or cooking class (using plants found in the region, of course), or catch one of the musical performances that are part of the garden’s concert series. Make a point to visit the Desert Terrace Garden for the best views of the surrounding buttes and desert.

Restaurateur Brooks Reitz built his name with this chicken-and-oyster joint that feels old-school despite its carefully crafted ambiance. On a first visit, it’s sinful not to order the perfectly salted, crispy/juicy fried chicken amalgam shellacked with a glaze of Old Bay and cayenne suspended in melted lard. That necessitates a second visit to gorge on the poached char-grilled lobster and sausage, or the Leon’s Fish Fry, a platter of shrimp, oysters and catfish. Leon’s was the first to open way-Upper King, now the restaurant hotbed, and it’s held onto its cool status thanks to its thoughtful buildout in a restored auto body shop, retaining the exposed rafters and a rollup garage door that opens to a patio out front.

I’m not one to skip breakfast, especially in Italy, where thoughts of cappuccino, pastries, and local ham tend to rouse me early from slumber. But on my first morning at the Hotel Sant’Angelo, in the old quarter of Matera, I was having a hard time dragging myself from the creature comforts of my cave. Staying in a cave, it turns out, can be surprisingly pleasant. There was just one small window high overhead, but the room and adjoining bath were in no way dank—a testament to the natural ventilation that keeps the caves cool and comfortable. The wavy contours of the white tufa-rock walls conjured a feeling of being enveloped in some primordial womb. Yet there were modern amenities: luxurious linens, Internet service, a telephone. Fred Flintstone never had it this good. I might have snoozed until noon, were it not for an impatient mate eager to see the sights. We had arrived in the village the previous night after a long drive across the treeless plains of the Basilicata region, located at the instep of Italy’s boot. Matera is an enchanted world of Stone Age splendor. Known as the sassi (Italian for stones), the bisque-colored hilltop cave homes comprise one of the oldest continuously inhabited places on earth, according to UNESCO. The caves have provided shelter for more than 7,000 years. A millennium ago, shepherds inhabited them and carved churches into the rock; during the Renaissance, the area prospered and elaborate buildings were carved out, the excess tufa sculpted into ornate facades. By the early 1900s, the sassi had fallen into neglect. Families and their animals crowded into the caves for warmth, and disease was rampant. When writer Carlo Levi brought this tragic state of affairs to light with his 1945 book Christ Stopped At Eboli, the Italian authorities moved residents en masse to modern housing—leaving the sassi abandoned, save for the occasional crew brought by film makers (Pier Paolo Pasolini and Mel Gibson among them) in search of a biblical-looking backdrop. It was only in the 1990s that the Italian government encouraged people to move back. Residents revamped the cave dwellings as homes, restaurants, and inns. When the Sant’Angelo opened in 2004, it was the area’s first luxury hotel. The 19 cave rooms are sparsely but tastefully appointed with rustic wooden furniture. Some carved decorations—crosses, hearts, an owl—date back hundreds of years. Fossilized shells embedded in the walls reveal that the region once lay underwater. Eventually, my fiancé and I did emerge from our cave to wander the town’s ancient alleys. A local guide named Dora Cappiello took us into some of the 150 chiese rupestri (rock churches), where she pointed out wine troughs and frescoes of San Nicola, the patron saint of local shepherds. We also visited a cave dwelling that had been restored to resemble its state when the caves were equal parts manger and living space.
Simple, delicious meals punctuated our explorations. The curvy walls of Baccanti, a cave restaurant, created a private nook where we feasted on silky pappardelle pasta with a cinghiale (wild boar) ragu, accompanied by a dry, fruity red aglianico from the nearby Vulture wine region. Tired and sated after a full day, we headed back to our cave—on moonless nights, a flashlight or trail of bread crumbs is advised for the stumble back to the hotel—where the promise of a deep, sound night’s sleep awaited. —Amy Cortese Hotel Sant’Angelo, 39/0835-314010, from $211 for a double. This appeared in the March/April 2010 issue.