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Ask anyone you know who grew up in the Bay Area about the Exploratorium, and they’ll likely be able to share stories of class trips and seeing their hair stand on end at an installation about electricity or fun-house mirrors that taught about optics and visual perception. This is not, however, a museum simply for kids—though curious kids will definitely be entertained while learning. Instead, its exhibits aim to raise the scientific literacy of visitors of all ages, by providing engaging, amusing, and hands-on experiences. Long housed at the Palace of Fine Arts, the Exploratorium opened in its current, and much larger, space on Piers 15 and 17 in 2013. One advantage of the new waterfront location is the North Gallery and its outdoor spaces, focused on environmental phenomena like the wind, rain, and tides. The completely dark Tactile Dome and the disorienting Monochromatic Room may prove not just the highlights of your visit to the Exploratorium but the most memorable, or at least strangest, moments of your time in San Francisco.

I’m not one to skip breakfast, especially in Italy, where thoughts of cappuccino, pastries, and local ham tend to rouse me early from slumber. But on my first morning at the Hotel Sant’Angelo, in the old quarter of Matera, I was having a hard time dragging myself from the creature comforts of my cave. Staying in a cave, it turns out, can be surprisingly pleasant. There was just one small window high overhead, but the room and adjoining bath were in no way dank—a testament to the natural ventilation that keeps the caves cool and comfortable. The wavy contours of the white tufa-rock walls conjured a feeling of being enveloped in some primordial womb. Yet there were modern amenities: luxurious linens, Internet service, a telephone. Fred Flintstone never had it this good. I might have snoozed until noon, were it not for an impatient mate eager to see the sights. We had arrived in the village the previous night after a long drive across the treeless plains of the Basilicata region, located at the instep of Italy’s boot. Matera is an enchanted world of Stone Age splendor. Known as the sassi (Italian for stones), the bisque-colored hilltop cave homes comprise one of the oldest continuously inhabited places on earth, according to UNESCO. The caves have provided shelter for more than 7,000 years. A millennium ago, shepherds inhabited them and carved churches into the rock; during the Renaissance, the area prospered and elaborate buildings were carved out, the excess tufa sculpted into ornate facades. By the early 1900s, the sassi had fallen into neglect. Families and their animals crowded into the caves for warmth, and disease was rampant. When writer Carlo Levi brought this tragic state of affairs to light with his 1945 book Christ Stopped At Eboli, the Italian authorities moved residents en masse to modern housing—leaving the sassi abandoned, save for the occasional crew brought by film makers (Pier Paolo Pasolini and Mel Gibson among them) in search of a biblical-looking backdrop. It was only in the 1990s that the Italian government encouraged people to move back. Residents revamped the cave dwellings as homes, restaurants, and inns. When the Sant’Angelo opened in 2004, it was the area’s first luxury hotel. The 19 cave rooms are sparsely but tastefully appointed with rustic wooden furniture. Some carved decorations—crosses, hearts, an owl—date back hundreds of years. Fossilized shells embedded in the walls reveal that the region once lay underwater. Eventually, my fiancé and I did emerge from our cave to wander the town’s ancient alleys. A local guide named Dora Cappiello took us into some of the 150 chiese rupestri (rock churches), where she pointed out wine troughs and frescoes of San Nicola, the patron saint of local shepherds. We also visited a cave dwelling that had been restored to resemble its state when the caves were equal parts manger and living space.
Simple, delicious meals punctuated our explorations. The curvy walls of Baccanti, a cave restaurant, created a private nook where we feasted on silky pappardelle pasta with a cinghiale (wild boar) ragu, accompanied by a dry, fruity red aglianico from the nearby Vulture wine region. Tired and sated after a full day, we headed back to our cave—on moonless nights, a flashlight or trail of bread crumbs is advised for the stumble back to the hotel—where the promise of a deep, sound night’s sleep awaited. —Amy Cortese Hotel Sant’Angelo, 39/0835-314010, from $211 for a double. This appeared in the March/April 2010 issue.

A short trip to the hilltop town of Monreale, just outside Palermo, offers the chance to explore some exceptional Norman-era buildings, most notably the Monreale Cathedral. The church’s interior has an extravagant mosaic that covers more than 6,000 square meters (66,000 square feet), much of it glittering with gold. Afterward, stroll through town to window-shop along the narrow lanes and enjoy the view of Palermo in the valley below.

When a place has not only the longest wooden bar in Texas (100+ feet) and is the oldest watering hole on the Riverwalk, you just know it’s worth a visit. But rather than rest on the above laurels, Esquire Tavern churns out some terrific and thoughtful scratch-made eats and drinks. From starters like pink peppercorn-flecked deviled eggs and mashed potato-filled tacos con papas to heartier fare like burgers, chicken mole and shepherd’s pie, the food takes comfort foods to the next level with fresh, well-sourced ingredients and modern executions. And as the icing on the culinary cake, the craft cocktail program here is award-winning and endlessly interesting. Plan for some enjoyable late nights at the Esquire on your next stop in SA.

With amazingly clear emerald waters, the calm sea off of Santa Margherita and Portofino is perfect for snorkeling and scuba diving (May-September is the best season, although it has been known to stretch!). Il Grande Blu provides all you need to enjoy the waters - instructors, equipment, even towels! And if you prefer to stay on top of the water, they have kayaks for rent, as well as a beautiful full-service beach. (If you are up for even more of an adventure - head even further around the bay to San Fruttuoso to scuba dive - there is a sunken Christ figure just a few meters out into the bay that is really gorgeous to view up close!)

Teatro Colón is considered one of the most beautiful theaters in the world. Though the theater was, to the great disappointment of many travelers, closed for years while undergoing major renovations, the Colón has now reopened and is playing host to a busy schedule of opera, ballet, and symphony. If you can’t get tickets for this legendary theater, try another elegant venue like Teatro Nacional Cervantes or Teatro San Martin. Check out Ciudad Cultural Konex if you’d rather see an edgier contemporary performance of modern dance or theater, or head to La Trastienda to hear live music by some of Argentina’s best young artists.

Ask any Montrealer the question “Which is the fanciest restaurant in town?” and chances are Toqué! will be a frequent answer. Indeed, quite fancy. But also quite expensive. Luckily, chef Charles-Antoine Crête, once mentored by Toqué’s Normand Laprise, decided that a more accessible and younger version of the famous restaurant would fit perfectly well with the new Place des Festivals—in style, location, and ambience. And he wasn’t wrong. I always go for the beef tartare, and not once have I been disappointed. The menu changes according to the season, but there is a constancy in quality, regardless of the time of the year. This is definitely the best way to get a taste of Montreal‘s finest, sans the waiting list and the steep check.

One of the few remaining tidal wetlands on the southern California coast, Batiquitos Lagoon in Carlsbad is full of hiking trails and a beautiful lagoon. Bird watchers will love trying to spot the 185 bird species, which naturalists can take in unique flora like pickleweed, lemonadeberry, and iceplant.

It didn’t seem to bode well that nearly a dozen buses were idling in the huge parking lot outside the giant modern building that overlooks Tokyo Bay from Kanaya Harbor. But the “tourists” that piled out of the buses were all Japanese, most from Tokyo, we were told, coming to shop in the market complex and dine in what, in San Francisco, would resemble a Fisherman’s Wharf restaurant. Ah, but the food was remarkable, and my lunch--above--was one of my favorite meals on the trip through the prefectures surrounding Tokyo on the Kanto plain. The name of restaurant? The Fish, of course. (If you get there, be sure to arrange a visit to the remarkable private Kanaya Museum across the street.)

The terrace outside this historic café boasts one of the best views in town, encompassing an almost unimaginable collection of architectural highlights and public art from the Renaissance. Linger over your coffee or a cup of hot chocolate as you gaze upon the Palazzo Vecchio, as well as a copy of Michelangelo’s David, the Fountain of Neptune, and the remarkable assembly of classical sculptures inside the Loggia dei Lanzi. It does cost more to sit outside than to stand at polished wooden bar inside, but this splurge is highly recommended. (The original owners were the official chocolatiers to the royal family of Savoy; you can take home a piece of that history in a beautifully wrapped box of chocolates or a jar of chocolate-hazelnut spread.)

Parco Sempione is Milan‘s biggest park and it has everything- cute caffès, picturesque setting, a medieval castle, a modern museum, a pond and charming foot bridges. If the sun is shining, this is the perfect place for a morning or afternoon walk, a lazy picnic or just a day off. The surrounding area includes beautiful residences, historic monuments, like Leonardo’s Last Supper and the Castel Sforzesco, restaurants and shops. Expect some interesting developments as the city gears up for World Expo 2015, including a super-contemporary visitor’s center in front of Castel Sforzesco.

Upon arrival try to snag the free daily garden tour! The gardens are divided into different ecosystems/themes such as the Australian Garden, Camellia Garden, Children’s Garden, Chinese Garden, Desert Garden, Herb Garden, Japanese Garden, Jungle Garden, Lily Ponds, Palm Garden, Rose Garden, Shakespeare Garden and the Subtropical Garden. Once you’ve finished the Garden tours, you can go to the Huntington Library, which is one of the largest research libraries in the United States. This is a nice escape from the big city if you have a day to spare while in Southern California. There is also a slew of different local restaurants to choose from including some found in Old Town Pasadena which is worth its own visit!

The Westin brand’s first foray into South America was, at least when it opened in 2011, the tallest building in all of Peru. That distinction has since been taken over by the Edificio Banco Continental (BBVA) nearby, but the glass-and-steel tower designed by Peruvian-born, Miami-based architect Bernardo Fort-Brescia stands over one of the busiest intersections in the city, and is still one of Lima’s most recognizable landmarks. While it was designed primarily to fit the needs of the growing number of high-end business travelers (the largest convention center in the city is attached to the hotel), the high-profile team, including interior designer Tony Chi, added on artfully modern touches. The striking interiors incorporate pre-Colombian motifs and gold, silver, and bronze finishes. The hotel is a hub of activity, with a full-service spa and high-end shopping, plus a lobby bar and lounges that serve as impromptu meeting spaces.

Pass over limestone rocks and through a protected landscape and you’ll arrive at this enchanting pool, which gets up to eight feet deep at times. Surrounded by volcanic outcroppings, it’s so removed from other island attractions that it feels undiscovered and romantic. The water is warm and bubbly and there are some ledges for sitting, all of which make you feel as if you’re in a natural Jacuzzi. Whether you arrive by foot, mountain bike, or jeep, the journey is as exciting as the destination itself. For a dose of adventure, opt for the half-hour guided horseback tour, which winds past caverns and other rock formations on its way to the pool.

Famous for its long history of handblown glassmaking, Murano sits just a few minutes’ ferry ride offshore in the Venetian Lagoon. The main attraction is the Glass Museum (Museo del Vetro), which recounts the history of glass through the centuries, with the largest focus on important pieces of Murano glass produced between the 15th and 20th centuries. You can also join a guided tour and catch a glassmaking demonstration here. When finished, do a bit of shopping for locally produced glass at some of the boutique shops. Also check out the Romanesque-style Church of Santa Maria and San Donato, which may or may not house the bones of a slain dragon under its boldly hued mosaic floor.