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A modest three-story building in the Ferreirasdorp area of Johannesburg, Chancellor House once contained the first black law firm in South Africa, opened by Nelson Mandela and Oliver Tambo at the height of apartheid. It was here that the two attorneys fought for those accused of crimes against the state—many of which they were also held accountable for later in life.

Left to languish for years, Chancellor House was restored to its former glory in 2010 and now features a freedom struggle museum on the ground floor. One particularly fascinating display includes a timeline with photographs and interesting events from Mandela’s life, including a picture of him sparring with Jerry Moloi on the rooftop of the South African Associated Newspapers Building. Many of the displays are also visible from the street so passersby can learn more about Mandela and Tambo while exploring the surrounding neighborhood.

Famous for bringing the world the likes of Arrogant Bastard Ale, Stone Brewing is nothing if not cheeky. This is, after all, the first American craft brewer bold enough to open an outpost in Germany, a country steeped in beer-making tradition. But Stone’s audacity is hardly unfounded, as you’ll discover when you visit the company’s headquarters in Escondido—ideally, for a private tour and tasting. If you’re not already a fan of San Diego’s particularly hoppy style of IPAs, there will be at least one beer on tap that makes you a convert. But first, you’ll walk through the brew house—past mash kettles and whirlpools and fermenters—to learn all kinds of fun facts, whether it’s the surprise source of the chocolaty notes in Stone’s porters and stouts (mega-roasted malted barley) or what the upcycling options are for spent grains (cow feed and dog bones). Pro tip: After your tour, bypass the lovely indoor restaurant for the even lovelier outdoor gardens—all bamboo and koi ponds and hummingbirds. Sit back in an Adirondack chair with a beer (try one of the extra-innovative brews on offer only here) and warm pretzels with Stone Ripper Pale Ale beer cheese sauce.

In the spirit of going big or going home, Hakkasan Las Vegas is a nightclub that basically outdoes all other when it comes to size and entertainment. To begin with, there is a two-story restaurant, which has a contemporary design and offers the perfect place to warm up for an evening in the nightclub. The club, which encompasses levels three, four and five, has a variety of rooms, each with its own feel and vibe. Level three consists of the Ling Ling Room and Club, which are chic and, in the case of the lounge area, dark and sleek as well. The main nightclub is located on the fourth floor; this is where party goers can watch DJs like Calvin Harris, R3hab and Tiesto perform. The fifth floor houses the Pavilion, which has an outside-type of energy. Come for dinner and stay all night long, rotating between the many nightlife experiences to say you’ve done a little bit of everything in Las Vegas.

At 185 acres, the Montréal Botanical Garden is less than a third the size of Mount Royal Park, but it manages to fit a remarkable collection of some 22,000 plant species and cultivars into that space, organized into 20 thematic gardens and including 10 exhibition greenhouses (ideal if you are looking for some tropical warmth in the depth of a Montréal winter). Everyone will have his or her own favorites when it comes to the different spaces—Alpine, Chinese, Japanese—but the First Nations garden stands out. Wandering alongside its pond and following its forested trails, you’ll feel like you are far from the city and instead in the northern reaches of the province of Québec—at least until you catch sight of the swoop of the nearby Olympic Tower, with its distinct incline. You can continue the naturalist itinerary at the Biodome, also nearby, where five different ecosystems of North America are re-created with flora and fauna—auks, lynx, penguins, and more.

The world’s seventh-largest public square is best known in the West for the 1989 student protests, but this is also where, on October 1, 1949, Mao Zedong founded the People’s Republic of China. The square was named for Tiananmen (which translates as “Gate of Heavenly Peace”), one of the gates of the former imperial city. It was built in 1651, then expanded in 1958 to four times its original size, and enlarged even further in 1976 with the construction of Mao’s mausoleum. Arrive at sunrise to watch the solemn flag-raising ceremony, performed with pride, precision, and a touch of flair.

The city’s most famous snowbird, architect Frank Lloyd Wright, spent winters at his home and architecture school in the Sonoran Desert. Taliesin West brings the horizontal lines and organic materials of Prairie School design to the desert landscape in low, skylighted buildings. Behind-the-scenes tours visit the pop-up structures that students have designed as living spaces amid the barrel cactus and paloverde trees.

Located in the center of Barbados in the highlands, the Harrison’s Cave underground system of rivers and caves is one of the Caribbean’s great natural wonders. Visitors tour deep inside the crystallized limestone caverns via small electric tramcars and are allowed to get off at certain points, including at a 15-meter-high (50-foot) “cathedral” and a “village” with multiple stalagmite columns. Lights illuminate the waterfalls, pools and magnificent geological formations.

Ask anyone you know who grew up in the Bay Area about the Exploratorium, and they’ll likely be able to share stories of class trips and seeing their hair stand on end at an installation about electricity or fun-house mirrors that taught about optics and visual perception. This is not, however, a museum simply for kids—though curious kids will definitely be entertained while learning. Instead, its exhibits aim to raise the scientific literacy of visitors of all ages, by providing engaging, amusing, and hands-on experiences. Long housed at the Palace of Fine Arts, the Exploratorium opened in its current, and much larger, space on Piers 15 and 17 in 2013. One advantage of the new waterfront location is the North Gallery and its outdoor spaces, focused on environmental phenomena like the wind, rain, and tides. The completely dark Tactile Dome and the disorienting Monochromatic Room may prove not just the highlights of your visit to the Exploratorium but the most memorable, or at least strangest, moments of your time in San Francisco.

What’s not to like about Museumplein? In summer, it’s as chill as Vondelpark, with picnickers playing instruments and getting high on the lawn. Add more grass and the field becomes stoners’ heaven as well as a magnet for art aficionados. The latter come for Amsterdam’s trio of world-class museums, all re-opened in 2013 after lengthy renovations—the stately Rijksmuseum, Stedelijk Museum of Modern Art, and the Van Gogh Museum. Tucked south of Leidseplein amidst upscale hotels and cafés, Museumplein is both a culture vulture’s paradise and an open space for those who want to escape the city buzz. In addition to repositories of priceless paintings, it’s home to the Concertgebouw at its southern end.

We picked up some gyros to-go during our stroll through the historic Plaka neighborhood below the Acropolis. Thespidos street was particularly memorable for the cafe we stopped at and discovering Brettos bar, which we decided to come back to enjoy as the end a lovely evening.

On sunny days, Parisians head for the Luxembourg Garden, built by Marie de’ Medici in 1611 and modeled after the Boboli Gardens in her native Florence. In addition to the magnificent Medici Fountain, there are more than 100 statues arranged around the garden’s 20 hectares (50 acres), which encompass both formal French and English gardens. Here you’ll find chess players, puppeteers, children sailing tiny boats on the octagonal pool and sometimes a free concert in the gazebo.

Big baggy aloha shirts—that could double as canoe sails—goodbye. Instead head to this Chinatown boutique, featuring the sharp, tapered designs of the eponymous Roberta Oaks. She draws on her hippie, farmhouse childhood and mid-century modern Hawai‘ian flair to create prints, which she then combines with a more fitted and form-flattering modern silhouette. These fabrics also take a star turn on graceful day dresses and even doggie bandanas. Open since 2009, this alluring boutique goes beyond attire, selling jewelry, candles, surf photography, and scents like Sándalo (a moody meditation on the islands’ vulcanism with ash, patchouli, and Royal Hawai‘ian sandalwood).

Tucked away on an eight-acre estate at the top of St. Helena’s main street, Harvest Inn could easily be mistaken for a private country manse somewhere in England, or even northern France. Its lush gardens are traversed by winding pathways, and its brick-accented, Tudor-inspired architecture suggests somewhere far more Old World than upstart Napa. Even its sinuous pools and cozy rooms (many with fireplaces and private outdoor hot tubs, mind you) are reminiscent of a style somewhat less rustic-chic than tends to be in vogue here in wine country. Indeed, by Napa Valley standards, the intimate inn is part of the old guard, its original 25 rooms dating back to 1975, just after the famed Judgment of Paris tasting brought the region’s New World wines into the international spotlight.

But the Harvest Inn is no less luxurious than the new resorts popping up all over Napa Valley. It has one of the most desirable locations in one of the most desirable parts of the world, surrounded by celebrated vineyards and presiding over arguably the most picturesque town in wine country. It also features a popular restaurant, Harvest Table, which serves dishes full of ingredients from the hotel’s on-site vegetable and herb garden.

Viñedos San Lucas is a new multi-use development fifteen minutes outside downtown. Its gracious, yet rustic hacienda vibe is attracting new neighbors plus locals and visitors to a complex that includes a quaint hotel and spa, two Mediterranean restaurants, one of the region’s finest wine cellars and even a polo ground. Vineyard excursions (don’t miss the lavender and olive groves) offer a glimpse of a Mexico few know; the mood is divinely bucolic. Time flies painlessly over wine and conversation, both outdoors and in.

Stroll 15 minutes through a lush rainforest to this gorgeous 40-foot waterfall grotto, located deep within the World Heritage site of Morne Trois Pitons National Park. Railings and a broad, well-maintained trail make the trip accessible even to non-hikers, though the tree-fringed pool—which is open to swimmers—gets unpleasantly packed when cruise ships pull into port. Serious photographers should haul along tripods and cable or remote shutter releases to capture the low-light, but oh-so-lovely scenery, which has become one of Dominica’s top attractions.