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Built on the foundations of a 16th century fortification, the Museo delle Culture del Mondo is housed in the 19th century Castello D’Albertis - the private home of the global traveler and collector of antiquities. Veer off the standard art/church museum trail, and up the massive staircase to the Castello, to see a beautifully preserved piece of Genovese history (and some super fascinating collections of global interest). While the walk is quite the hike, the view from the top floor library of the museum is stunning.

Chef Peter Schintler’s San Juan restaurant remains one of the capital’s top fine dining destinations after more than a decade in operation. Marmalade, located in Old San Juan, has allowed Schintler to experiment with international flavors and techniques picked up at previous stints in kitchens around the world, including one at New York’s fabled Le Cirque. While beloved by omnivores and travelers who will jet-set for cocktails, vegetarians especially appreciate Schintler’s menu, which includes a spiced cauliflower meze and hand-rolled black truffle pappardelle. Reservations are definitely recommended.

Prior to being rechristened as Independence Hall, this building was used and known as the Pennsylvania State House. The founding fathers of the United States met here in the Assembly Room to debate and adopt both the Declaration of Independence and the United States Constitution. For a time the building fell into disrepair, but an 1824 visit from the Marquis de Lafayette (who had served as a soldier under George Washington) compelled the city to rescue and preserve this historic site. Entrance to Independence Hall is by guided tour only; tickets are required from March through December, but no tickets are needed in January or February. Fun fact: For a short time, the basement served as the city’s dog pound!

At this Charleston hit, James Beard Award–winning chef Sean Brock reinterprets traditional Southern dishes with a steadfast commitment to local and regional ingredients—the restaurant even has its own garden. Constantly changing, the menu is filled with inventive new takes on Southern cuisine, such as pig’s ear lettuce wraps done up “buffalo” or “Kentukyaki” style.

Don’t miss the Carolina Grouper—it’s one of the most beautiful dishes at this establishment, and a regional classic you have to try while visiting Charleston.

Note that the restaurant also has locations in Nashville, TN and Savannah, GA.

Founded more than a century ago, the US Grant gracefully mixes its historic legacy with contemporary touches. Ulysses Grant Jr., the son of President Ulysses Grant, began construction on the property at the turn of the 20th century. A time capsule filled with family photos and newspaper articles that he left in 1907 is now part of the hotel’s permanent collection. Since opening in 1910, the hotel has played host to 14 presidents. For a dose of culture without leaving the property, check out the Celebration Fine Art Gallery, where you can view paintings, sculptures, glasswork, and ceramics by national and international artists.

Today, the US Grant’s prime downtown location in the Gaslamp Quarter is hard to beat. When you enter the Grand Lobby, crystal chandeliers and hand-loomed carpets provide a sneak peak of the elegant decor found throughout the property. Guest rooms impress with tall ceilings, Empire-style furniture, and commissioned French and Native American art. No detail has been left out; even the headboards—one-of-a-kind figurative drip paintings—are a work of art.

The sprawling contemporary museum, MASS MoCA, is responsible for bringing North Adams to life, and offers some of the most cutting edge art around. Xu Bing’s Tobacco Project {above} is made from over half a million cigarettes arranged to mimic a tiger skin rug. It makes a thought provoking statement on the global tobacco trade, luxury and colonialism, and is typical of the installations you will see there. The complex also hosts a variety of musical events including dance and films. Luckily Split, the in house restaurant has coffee, treats and tasty lunches.

Roseau’s only oceanside dining option, the elegant Palisades pairs sweeping water views with one of Dominica’s best culinary experiences. Here, creative dishes showcase the island’s natural bounty, including produce sourced from local farms and fish straight from the Caribbean Sea. Start with dishes like BBQ jerk octopus and sesame-crusted tuna with a soy-chili dip. Then, move on to the lion fish, served with green-banana croquettes and mushroom sauce. Fancy something lighter? Try a lentil-black-bean cake or callaloo soup, made with baby taro leaves, coconut milk, yam, and green bananas.

You’ll go for the fresh fish--namely salmon, black cod, and halibut. But you’ll want to stay forever thanks to the increasingly-excellent restaurant scene. Yes, Alaska is finally on the map when it comes to destination dining. Enjoy one of the state’s top dining spots right outside Denali National Park, stellar wine lists all around Anchorage, and plenty of smoked salmon all down the Kenai Peninsula. Pro tip: Head to the top floor of the Captain Cook Hotel on clear nights for apps and cocktails and a view of Cook Inlet that you’ll never forget.

On a perfect spring day, Boston turns into a giant walking tour. The city’s top attractions tend to spill over from one to the other, inviting visitors to just keep going. On other days? Well, luckily there’s the T. For one of America’s most celebrated walking tours, walk the Freedom Trail, which takes you to 16 sites central to American history, including the Massachusetts State House and the Paul Revere House and so much more. Here are some of the best things to do in Boston.

Thanks to its views across Charleston Harbor, the Edmondston-Alston House is one of the city’s most popular historic homes open to the public. Its hyphenated name joins that of its builder and of the rice planter who purchased it from him just a decade later. The mansion, with its Corinthian columns and rooftop piazza, is a prime example of the Greek Revival architecture popular in the early 19th century. The house was at the center of several key Civil War events: as a lookout spot for Confederate general P.G.T. Beauregard during the siege on Fort Sumter in April 1861, and as a refuge for General Robert E. Lee on the night of the Great Charleston Fire of 1861. The mansion is owned by the Alston family, and its interior is preserved to look much as it did 150 years ago.

On clear days—"when the mountains are out,” as locals say—this steep, ice-gilded volcano dominates Seattle’s horizon. In fact, the peak is 90 miles southeast of the metropolitan area. You can see lush green forests blanketing about 60 percent of Mount Rainier National Park, while the rest is covered in meadows, alpine heather, and the densest patch of glaciers in the contiguous United States. Easygoing hikers like to explore the wildflower meadows near the 1916 Paradise Inn, which transform into prime terrain for sledding, snowshoeing, and igloo-building come winter. Prefer the thrill of downhill? Head to Crystal Mountain, just northeast of Rainier, where the state’s first ski gondola still serves its most elevated restaurant.

Cape Flattery is the northwesternmost point of the contiguous United States. It is in Clallam County, Washington on the Olympic Peninsula, where the Strait of Juan de Fuca joins the Pacific Ocean. It is also part of the Makah Reservation, and is the northern boundary of the Olympic Coast National Marine Sanctuary. Cape Flattery can be reached from a short hike, most of which is board walked.

South of San Pedro is the award-winning luxury resort of Victoria House. The plantation style property is unlike any other on Ambergris Caye, offering some of the best views of the Caribbean Sea. Despite being one of the larger properties with 42 rooms spread out over 10 acres, Victoria House is one of the most intimate resorts. A majority of the staff at Victoria House have been there for years and it shows. Their love for Victoria House and its guests is genuine and evident throughout every part of the resort. Look for several dining options on property, including the more casual Admiral Nelson Bar, perfect for daytime dining, and the more high-end Palmilla, an ideal spot for a romantic dinner. Meal plans are available for guests looking for a more all-inclusive experience. Victoria House offers a range of room styles, from staterooms and plantation rooms to private suites and villas. Rates start at $195 for staterooms all the way up to $1,775 for a five-bedroom villa.

Nick’s is a Southern California institution, with coastal locations in Long Beach, San Clemente, Manhattan Beach, and Pasadena. The Laguna outpost has the others beat, however, thanks to its perch just across the street from Main Beach. Diners can head here after a long day in the sun for delicious takes on classic American dishes, from buttermilk fried chicken and San Francisco cioppino to rib eye melts and cheeseburgers with Thousand Island dressing. Whatever you choose, pair it with a house cocktail (you can’t go wrong with the jalapeño-watermelon margarita) as you watch the sun set over the Pacific.

Spanish colonial fountains. Roaring outdoor fireplaces. Brightly colored bougainvillea vines and hibiscus flowers. Rancho Valencia Resort & Spa, Southern California’s only Relais & Châteaux, is spread over 45 hilly acres of gardens and groves. No detail is too small here, as you’ll discover on the Bridge of Champions, a narrow wooden span that leads you across a brook. As for the champions in question, they’re bygone net men memorialized on the path to the resort’s fabled tennis complex: 18 courts and a pro shop. Not to be outdone, the landscaping around your casita (or luxury villa or private hacienda) will lend a secret garden feel to your patio, where you may also find a private fireplace, hot tub, or—in the case of the hacienda—heated pool. Inside, expect 600-thread-count linens, Frette towels, and a Bang & Olufsen sound system. At the spa, waterfalls and a yoga pavilion that appears to float work in tandem with the treatments to induce maximum relaxation.