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Wynn Las Vegas, and its younger sister Encore, are known as some of the nicest properties in town, and for good reason. The suites are spacious and clean, the beds are comfortable, there is a lot of room in which to spread out and the views are stellar. Beyond the rooms themselves, the rest of Wynn is equally as beautiful, with fine art located throughout the property, very helpful staff, high-quality restaurants (all of which have at least one vegan option on the menu) and a general ambiance that feels classy, not trashy. This is a great hotel for honeymooners or couples, or for people who want a high-end Las Vegas experience that makes them feel like more than just another visitor in the city.

Who knew Malta was so pretty? Well, I suppose the people who live there knew. I didn’t. There was, to be fair, a lot I didn’t know about Malta, including that the national language is actually Maltese, which sounds like no Mediterranean language you’ve ever heard. But one of the most unexpected delights were the narrow streets of the capital city, Valletta. The closed balconies that jut from almost every house are a major feature; they’re the first thing you see as you walk down Republic Street, the city’s main thoroughfare, where they are painted a uniform dark green. Meander away from the shops and into some of the smaller residential streets, and you will be rewarded with a wider palette. Bright reds and yellows, cornflower blues, pastel greens, and dusky pinks—it’s like something out of a fairy tale. Go feast your eyes.

Little-known fact: New Orleans was the first place in North America to license pharmacists (starting in 1769, when the city was still under Spanish rule). After Louisiana became a territory, the U.S. governor extended the requirement, also decreeing that pharmacists take a three-hour licensing exam in order to practice. And no wonder illness got such attention—the city was arguably the least healthy place to live on the continent; it was riddled with yellow fever, malaria, and dysentery. This dark but fascinating history is explored in this atmospheric 1822 town house, which was once the home and shop of Louis J. Dufilho, the first licensed pharmacist in the city—and hence in the country. Exhibits include apothecary jars, tools of the trade, and leeches. (Yes. Leeches.)

This 1st-century wonder will take your breath away. Not only is it one of the city’s most ancient sites, it’s been in continuous use for centuries. Originally built as a private temple, today it is a Catholic church and the resting place of Italian kings and the artist Raphael. Make the most of a wet day in Rome and watch as the rain falls through the center oculus.

The Peak 2 Peak Gondola that connects Whistler and Blackcomb mountains was considered a glitzy and expensive PR move when it opened in 2007. Today the 1.9-mile span, the longest unsupported span in the world, ferries hikers, bikers, and of course, skiers and snowboarders to the slopes they seek. Best of all, the Peak 2 Peak provides access to alpine wilderness usually reserved exclusively for the athletically inclined. (This is the adventure I take my 83-year-old mother on in Whistler, and she is blown away, as is her 8-year-old grandson.) Flying through the air, 1,431 feet up with hardly a support tower in sight, is a thrill. The 11-minute ride soars above snow walls, wildflower meadows, Fitzsimmons Creek, and several trails down, around, and behind the Whistler peaks.

This glitzy shopping district in the city center is home to department stores and shopping malls like Ginza Six and Tokyu Ginza Plaza. There are many Michelin-starred restaurants for sushi, tempura, and kaiseki, as well as classic bars such as Star Bar and Bar High Five. Casual restaurants serving tonkatsu, Western-style yoshoku, and old-school kissaten cafés also pepper the area, offering something for everyone regardless of budget. The area is rich with so-called antenna shops (regional food shops), and fans of the lifestyle store Muji will not want to miss the flagship store. Ito-ya and Kyukyodo are must-shops for stationery, traditional washi paper, and pens.

Even with all the noted thinkers, artists, politicians, and powerful families who’ve called Florence home, Leonardo da Vinci is arguably the city’s most famous son. This homage focuses less on his artwork and more on Da Vinci’s forward-thinking inventions and theories. The exhibits are separated into five themes, with each including models based on Da Vinci’s instructions. The Earth section includes pieces like printing machines and an oil press; Water has hydraulic saws and water floats; Fire boasts military artillery inspired by the Atlantic Codex; Air has Da Vinci’s parachute, flying machine, and “winged man” paragliding prototype; and Mechanisms includes items based on Da Vinci’s codexes, to demonstrate their principles. Most items are hands-off, but kids will have fun learning how to operate the rotating crane and other models. Most of the pieces are made of wood, so you really get a feel for their bones—and for Da Vinci’s genius.

The English novelist D.H. Lawrence came to New Mexico to recuperate after being diagnosed with tuberculosis. This 160-acre ranch, gifted to him by Mabel Dodge Luhan, is where he started work on his novel The Plumed Serpent. He wrote underneath a tall ponderosa pine, immortalized by Georgia O’Keeffe in her painting The Lawrence Tree. Take a tour of Lawrence’s estate, including the famous tree, “standing still and unconcerned and alive,” as Lawrence once wrote.—By Edmund Vallance

Open for breakfast, lunch, dinner, and late-night fare, this bistro-style American eatery is located in the lobby of the historical Continental Bank, right in the middle of downtown. Chef Nathan Powers and his team draw locals working nearby, tourists from afar, and businesspeople looking to impress and woo clients. The menu for each of the meals served throughout the day is sophisticated but not overwhelming, and Powers slowly rotates items as the seasons change and new inspiration strikes. Bambara offers a number of seafood dishes and provides a range of portion sizes to accommodate different appetites.

See some of Sicily’s most prized artworks at the Regional Gallery of Sicily, housed in the Palazzo Abatellis, in Palermo’s Kalsa neighborhood. The palace’s Catalonian Gothic–style architecture, which dates from the 1490s, is worth a visit in its own right. Among the prominent works in the collection are the Virgin Annunciate by Renaissance artist Antonello da Messina and a sculpture of the head of Eleonora of Aragon by Francesco Laurana.

Arguably the most luxurious yoga resort in Bali, Como Shambhala has 30 rooms, suites, and villas set on 23 acres of jungle-covered riverbank near Ubud, each with its own butler and infinity pool. Yoga programs led by visiting masters such as Rodney Yee are held throughout the year and typically include five hours of daily practice over five days. The spa offers Balinese and Ayurvedic treatments, and off-site activities range from jungle treks to visits to Ubud’s famous temples.

With Indonesian names that translate to earthy concepts like “wind song” or “forest in the mist,” the terracotta and thatched-roof residences at the 22-acre Como Shambhala Estate encourage quiet reflection. They jut from the hillsides and line the Ayung riverbed, offering refuge from the frenetic scene nearby in Ubud.

Most people come here as part of a yoga or health retreat, and everything—from the dining experiences to the custom health programs—is designed to guide guests toward reaching their wellness goals with help from a cadre of resident experts, including a dietician, Ayurvedic doctor, reflexologist, and an Oriental medicine specialist, as well as fitness, yoga, Pilates, and qigong instructors. But it’s not all work. After a day of rugged outdoor adventure—the resort can arrange for hiking, biking, and paddleboarding down the Ayung—retire to your private spring-water infinity pool and meditate on the events yet to come.

Owned by a Japanese-Israeli couple, Sakana is situated near the red cliffs of Vagator Beach. The interior is fittingly adorned with photos of sake and kimonos, and an oversize sakura tree sparkles with white lights. Though one of few Japanese restaurants in Goa, Sakana still works hard to stand out with traditional dishes like sushi, udon noodles, beef yakiniku, salmon rolls, and chicken katsu with pickled radish. The sake is flowing, naturally, and there are cocktails and refreshers like lemon soda on hand, too. If they’re available, order the amaretto or cherry ice cream for a light and sweet finale. Note: Sakana is closed during monsoon season, so make sure you eat there before the end of May.

This shop is more coral sanctuary than ordinary jewelry store. In addition to selling mind-blowing designer pieces, this is the place to learn all about the Adriatic coral: where it lives, and how it is sourced, harvested, and treated to become that deep-red stone used in jewelry. You can watch this magic will happen right before your eyes if you drop in here for a chat with a member of the impressively knowledgeable staff, who will tell you everything you want to know in the time you have available. Get inspired, and then check out the pieces, some of which feature typical Dubrovnik filigree work. Like unique works of art, each item comes with a certificate of authenticity.

My ideal habitat is a warm day on a tropical beach. I’m also a sucker for beauty in all its most unusual forms (part of the reason I’m on the Board of Burning Man). So, when I heard about the Harbin International Ice & Snow Festival in northeast China (Manchuria meets Siberia: that just sounds frozen!), my initial reaction was, “How far would I travel and how cold would I get all in the name of experiencing an aesthetic phenomenon?” So, after 90 degree humidity in Malaysia, two planes delivered me to this cursed, desolate part of China (20 degrees below zero). Amidst the Siberian wind gusts and short days of daylight, Harbin is a revelation, a place where the light of collective aesthetic joy is experienced by 800,000 visitors annually for the Ice & Snow Festival (90% from China as this is one of the country’s top winter destinations). Oddly, I kept having Burning Man flashbacks...night being preferred over day due to the psychedelic visuals enhanced by the dark, the fact that thousands of artists (15k in Harbin) labor 15 days around the clock to create something out of nothing only to know that these beautiful structures will either melt (Harbin) or burn (Burning Man), and, finally, the sense that no picture or video can capture the sensory overload of being surrounded by spectacle. Think: “You had to be there.” Remember the spectacle of the 2008 Beijing Olympics Opening Ceremony? I heartily recommend this trek that takes place late December through February.

The hike up Lion’s Head affords incredible views. Since the trail winds around the mountain, you’ll have the unique opportunity to see every side of Cape Town from above. When you start, the ever-stunning Table Mountain will be just to the left, but soon enough, you’ll be facing Robben Island in the distance, with all of Cape Town below. The Lion’s Head hiking trail is eight miles round-trip and takes about three to four hours to complete, depending on your pace. If you happen to be in town during the full moon, be sure to start hiking mid-afternoon and bring your headlamp and a picnic dinner. Along the way, you’ll meet many a local honoring their monthly tradition of hiking up, eating dinner during the sunset, and hiking back down in the moonlight glow.