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Though it was built in 1968, Hotel de Mendoza reflects its 16th-century surroundings. Nestled in the heart of Guadalajara’s centro historico, the hotel features 104 simple yet elegant rooms, with hand-carved, colonial-style furnishings (some hand-painted by Jalisco artist Alejandro Rangel Hidalgo) and views of Teatro Degollado. Original arches salvaged from nearby Templo Santa María de Gracia’s former convent create architectural contrast in the courtyard pool area, a sunny space lined with terra cotta tiles and cascading greenery. Similarly atmospheric is the on-site restaurant, La Forja, where guests enjoy global cuisine in an elegant dining room decorated with cane-backed chairs and blue-and-white talavera pottery.

The Vines of Mendoza Tasting Room is owned by a private real estate group of the same name. It is not to be confused with The Vines Wine Bar & Vinoteca located in the Park Hyatt Mendoza hotel, which too is owned by The Vines of Mendoza. A pioneer in Mendoza’s hospitality scene, The Vines of Mendoza was one of the first places in the province to offer its guests guided wine flights in a communal tasting room. Bilingual wine experts well-versed in Mendoza’s varietals are friendly and informative. It’s a great place to sample hard to come by wines from local boutique wineries. With over 1,300 wineries in the Mendoza region, the Vines of Mendoza Tasting Room can take you on an intoxicating wine tour without ever having to leave your seat. But good luck getting out of it by the time you are done! Espejo 567; +54 261 438-1031.

Avenue Arístides Villanueva, simply known as Aristides by the locals, is Mendoza‘s main nightlife drag. Lined with bars, Irish pubs, restaurants, dance clubs and hostels, Aristides is where all the action happens. In warm weather months, crowds flock to the outdoor tables lining the sidewalk. It’s a great option for bar hopping and getting a dose of the late-night Mendocenan culture.

The hike up Cerro de la Gloria in General San Martin Park is a steep 45-minute trek but worth the panoramic city views. Make sure you bring lots of water and go early in the day before the weather is too hot and the views too hazy. At the top, you’ll also be rewarded with an impressive bronze monument honoring the Army of the Andes led by Argentina liberator General San Martin, a battalion he marched from Mendoza to Chile to free the country from Spanish rule. The memorial was built to commemorate the Argentina Centennial of 1910. If you’re too tired to climb back down, you can take the public bus, but will need exact change to ride (check current price at the tourist office).

Susana Balbo, Argentina’s first female winemaker, owns the Agrelo winery Dominio del Plata. The restaurant, Osadia de Crear, which translates to “dare to create,” offers a fusion of Argentinian and Mediterranean seasonal cuisine using local ingredients like Mendocenean tomatoes, domestic goat meat, and herbs from the garden. The caprese salad, the roll of suckling goat, and the cheese and sweets dessert are highlights on the menu. The restaurant also has a deli, offering meat and cheese platters, fresh salads, and gourmet sandwiches made with homemade bread. Picnic baskets are available for guests who want to dine alfresco among the vines. Don’t leave without trying the Susana Balbo Signature Cabernet Sauvignon, which is the winemaker’s personal favorite. Cochabamba 7801, Agrelo, Lujan de Cuyo, Mendoza; [email protected]; +54 261 498 9200

As the saying goes, “When in Rome...,” and in Mendoza, this means slipping into an immodestly cut bikini bottom to blend in with the locals. Get rid of those American tan lines with some of the most adorable bikinis in the southern hemisphere. Two young Mendocenean sisters design and stamp the bathing suits themselves, making each one slightly unique. You can mix and match tops and bottoms for size and cut. The only question is, do you have enough courage to wear it back at home? With your flattering new tan lines, you just might.

Bodega Los Toneles is a meticulously restored winery located in downtown Mendoza, just three minutes from the city center. The restoration was so faithful to its original 1920s architecture that it has been declared a Cultural Heritage site of Mendoza. A stunning blend of traditional and modern, Bodega Los Toneles offers walking tours through the winery (the event space is breathtaking) with the opportunity to learn about winemaking. Wine tastings are offered Monday thru Saturday from 9am to 6pm. The restaurant, Abrasado, offers gourmet cuisine in one of the private rooms or grand halls overlooking the wine cellars. Lateral Acceso Este 1360, Guaymallén, Mendoza; +54 261 431-0403

A refined yet rustic restaurant and guesthouse nestled into the rural landscape of Mendoza’s Uco Valley, Finca Blousson is a hidden treasure for wine lovers seeking life’s simplest pleasures. Pair the Bistro’s blend of Argentine and French Provencal fare with wines sourced from the region’s top local boutique wineries, and you’ll be treating yourself to an unforgettable experience. The intimate country guesthouse has three cozy rooms overlooking the vineyard or a spectacular view of the mountains. Owners Victoria Jones and her French partner, Patrick Blousson, will look after you like a member of their own family. Route 94, km 14, on the road to The Manzano Histórico, Tunuyan, Valle de Uco, Mendoza; +54 9 261 15 655 3382

I love the wines of Mendoza, Argentina, but I wanted to marry the wines of Catena Zapata when I had the chance to drink them whilst overlooking the green vineyards backdropped by the soaring, snowcapped Andes peaks. The wines of Catena are mostly big reds made from malbec or cabernet, and they make some chardonnay and sauvignon blanc as well. The winery is fashioned after a stepped Maya pyramid and is furnished with state of the art equipment. Wine tours last about an hour and a half and finish at the tasting room, where you can purchase bottles of wine. Catena Zapata and the rest of the Mendoza region wineries are only open by appointment, so be sure to have a day’s worth of wine tours booked in advance for your itinerary. Be sure not to skip over the city of Mendoza, as there are many wine tasting rooms featuring wines from the region and selling limited releases and other rarities not readily available at the wineries.

Bonafide is a classic Argentine café whose roots reach back to 1917 in Buenos Aires. The name stands for “good faith” to reflect his family’s history in the coffee business and a symbol of trust for his clients. They also sell “Bocaditos” (sweet bites) and “Nugaton” (wafers filled with nougat cream), which have become classic Argentine chocolate snacks. Peatonal Sarmiento 102 - Mendoza. Tel: +54 261 423-7915

Posada Borravino is tucked away along one of Mendoza’s oldest poplar-lined streets in the city’s Chacras de Coria neighborhood. The country inn has eight distinct guestrooms that offer a peaceful respite in a quiet Mendocenean neighborhood. The hotel’s design is simple but elegant. Rooms feel clean and refreshing with rustic yet stylish furniture, patina walls, and high, white-washed wooden ceilings.

A boutique hotel experience in every sense, here guests frequently mingle in the sun-drenched living room and cultivate friendships over bottles of malbec and long evening asados (barbecues). The back garden provides an inviting place to enjoy a good book, dip in the small swimming pool, or simply soak up the tranquil atmosphere. The staff is friendly and knowledgeable about what to do and see in Mendoza—from winery tours to adventure activities. In the evenings, Posada Borravino is lit up by dozens of scented candles, creating a magical ambience that casts a rosy glow on your entire stay.

Possibly one of the most recognized malbec wine labels by the American market, Bodega Norton is one of Mendoza’s most prolific wineries. Founded in 1895 by the Englishmen Edmund James Palmer Norton, the winery has grown significantly under its Austrian management since 1989. Each year, Bodega Norton continues to garner serious accolades for its wines and talented winemakers. During the harvest season, Bodega Norton offers a variety of experiences for wine lovers to get their hands dirty in the vineyard. You can harvest the grapes, picking them off the vine and tasting the flavors of the different grape clusters. You can also choose to be a winemaker for the day, creating your own “blend” of wine, combining varietals and discovering their aromas, textures and complexity. Both experiences require 24-hour advance reservation. Ruta 15, km 23.5, Perdriel, Luján de Cuyo, Mendoza; +54 261 490 9700

If you’re looking for a day of grape-free respite in Mendoza, head off-the-grid to the hot springs of Cacheuta. The Terma Spa welcomes guests with an assemblage of thermal baths overlooking the scenic Mendoza River flowing downstream from the Andes. The indoor/outdoor thermal spa circuit winds through waters ranging in temperature from 73 to 105 degrees. Bubble beds, a water volcano and foot baths are strategically placed throughout the circuit to knead tense muscles. The Natural Solarium has a basin of therapeutic mud for slathering all over your body and baking on the pool deck. Scrub yourself clean in the bithermal hydrojet shower and kick back on the flowering Andaluz patio. Next, head underground to the vaporarium and detoxify in its natural steam. Relax in the verdant garden until you’re ready for an afternoon spa treatment or another convalescing soak in Cacheuta’s healing mineral waters.

O. Fournier is a modern architectural marvel located 80 miles (90 minutes) from downtown Mendoza in the district of San Carlos. It is one of Valle de Uco’s farthest wineries to visit, but it’s worth the drive to enjoy O. Fournier scenic views, distinctive design, and award-winning restaurant. José Manuel Ortega, a Spanish banker, bought the land in 2000 and contracted local architects to begin building O. Fournier in 2002. No expense was spared and no detail was overlooked to achieve Ortega’s vision. His talented wife, Nadia Harón, who delved into her passion for cooking when the pair moved to Mendoza, has become one of the country’s most notable chefs. Her restaurant, Urban at O. Fournier, blends Argentine and Mediterranean-Spanish flavors and traditions using fresh ingredients grown on the property’s 650-acre farm. If you find yourself falling in love with O. Fournier’s wine and landscape, you may just be tempted to purchase a small plot of land from Ortega to harvest your own wine and create your own signature blends. Reservations to visit the winery and restaurant must be made in advance.

Beef is everywhere in Buenos Aires, but there are a few parrillas in town that stand above the rest for quality. Within that category, La Cabrera offers a unique experience. Yes, the focus is on the meat, but the sides almost steal the show—surprising vegetable dishes accompany each entrée, and in sharable portions. It’s typically packed with locals and tourists alike, so expect long waits any night of the week. That said, for those who can live with dinner earlier than Argentina’s customary 9 p.m. or later, La Cabrera offers an early seating they call “happy hour” that’s wait-free and includes a 40 percent discount on all menu items.