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As tourists gaze up at Michelangelo’s dome in St. Peter’s Basilica, many have no idea that one of Vatican City’s most compelling historic sites is directly beneath their feet: the Vatican Necropolis, also known as the scavi (excavations). This multilevel subterranean area tells the story of Vatican Hill’s ancient Roman suburban beginnings. Take a walk through a 1st-century C.E. necropolis (once a cemetery and mausoleum), 5th-century Christian burial area, the Vatican grottoes, and the original 4th-century church foundation walls.

Buenos Aires is so grand that the El Centro (city center) district alone has more historic sites than many world cities. As you stroll, you’ll view the iconic Obelisk, which overlooks the main Avenue 9 de Julio, and the Plaza de Mayo, where Evita addressed throngs of her followers from the balcony of the Casa Rosada. The churches are works of art—the Baroque Basilica of San Francisco is only one example—and even the office buildings are worth seeing (check out the elegant Palacio Barolo). In all, the architecture rivals that of any city in Europe.

The 921-meter long Valens Aqueducts - a prominent landmark in Istanbul’s Fatih district - played a vital role in supplying water to the people of the Byzantine and Ottoman empires. The Roman Emperor, Valens ordered the construction of the aqueduct in late 4th century AD to feed water from the hills beyond Istanbul to hundreds of underground cisterns inside the city, including the famous Basilica Cistern located opposite the Hagia Sophia. The best place to view the towering stone aqueduct today is where it crosses the busy Ataturk Boulevard near the Mosque of Şehzade. The boulevard is the main thoroughfare between Taksim Square and the Aksaray neighborhood.

An active parish of the Roman Catholic Diocese of San Diego, Mission Basilica San Diego de Alcalá remains a tranquil place of worship and reflection. Regardless of your religious beliefs, the first of California’s 21 missions is well worth a visit for its extensive history. It was originally constructed in Presidio Park in 1769 but moved inland to its current site just five years later. Records show that it was the first place in California to cultivate olives; tree cuttings from this mission would later be used to found olive groves at other missions around the state. It’s also home to the grave of Father Luis Jayme, the state’s first Catholic martyr; he was killed when American Indians stormed the mission in 1775 and is now buried next to the altar. Destroyed many times over, the mission was most recently rebuilt in the 1930s, but looks as it would have in the early 1800s.

High atop Montmartre is this distinctive white church, Sacré-Cœur, or “sacred heart.” Constructed of travertine stone (the same used in the Arc de Triomphe), the Roman Catholic Church took nearly 40 years to complete and five more years to be consecrated (in 1919). If you choose to approach the church from below, it’s around 100 steps, and if you want to climb up into the dome, it’s another 270. Your reward for all that exercise is a stunning view of Paris unfolding below. Also worth noting: the basilica’s campanile houses La Savoyarde, the largest bell in France, weighing in at 19 tons.

The choice of whether to build a church following a Gothic Revival or neoclassical design involved more than just aesthetics in 19th-century Québec. The former tended to be associated with Protestantism, and so the construction of the Catholic Basilica of Notre-Dame in that style raised eyebrows. When the St-Jacques Cathedral was destroyed by fire in 1852, the architects who designed a new church for the site, the Mary Queen of the World Cathedral, opted for the neoclassical style that was more typical of Catholic buildings. Constructed from 1874 to 1895, it is a quarter-scale version of St. Peter’s in Rome, complete with coffered vaults and twisting columns in imitation of those of Lorenzo Bernini’s baldachin in the Eternal City. The building’s green copper dome makes a statement, too, looming as it does over the largely Protestant neighborhood. The stucco crucifix by sculptor Philippe Hébert is one of most important works of art in the church.

This leather workshop is hidden away in a former Franciscan monastery next to Santa Croce. The Scuola del Cuoio was originally founded to provide skills and work for some of the city’s orphans after World War II; masters and apprentices still produce wallets, purses, journals, and jackets. Take a quick tour of the beautiful cloisters, frescoed corridors, and workspace, or sign up for a full workshop and try your hand at making something of your own. Everything is crafted on-site using traditional methods. Be sure to get your purchases personalized with a gold-stamped monogram.

This 1st-century wonder will take your breath away. Not only is it one of the city’s most ancient sites, it’s been in continuous use for centuries. Originally built as a private temple, today it is a Catholic church and the resting place of Italian kings and the artist Raphael. Make the most of a wet day in Rome and watch as the rain falls through the center oculus.

This pink-marble waterfront edifice in Piazza San Marco dates back to the 14th century, when it was the residence and seat of government for the doges (rulers) of Venice. Today the ornate Byzantine- and Moorish-influenced Gothic Palazzo Ducale is a symbol of the city, and serves as a museum hosting some of Venice’s most important art, including the famous Bacchus, Venus, and Ariadne masterpiece by Tintoretto. It also runs the popular Secret Itinerary and Doge’s Palace Hidden Treasures tours. After you’re done, treat yourself to a glass of wine in the small on-site bistro, with windows looking onto the Grand Canal adjacent to the Bridge of Sighs.

Sitting right next door to the Basilica of Notre-Dame in the heart of historic Montréal, St-Sulpice Seminary is the second-oldest building on the island. (The oldest is the 1671 LeBer-LeMoyne House, roughly six miles from the center of the city, which now houses the Musée Lachine.) The seminary dates from 1687, and remarkably it is still used for its original purpose: to house and train Sulpician priests. Sadly, this means the building is rarely open to the public. (Rarely is not an understatement here—apart from some tours in 2017, the last time the general public was allowed through its gates was in 1967 during the Expo.) Though you can’t tour the building, you can admire its gray stone architecture from the street. Especially noteworthy is the clock on the façade, built in Paris and installed in 1701, making it one of the oldest such clocks in North America.

From the luxury Oetker Collection, Le Bristol is one of the first hotels in France to obtain Palace distinction. Occupying nearly an entire block on Rue du Faubourg Saint-Honoré near the Élysée presidential palace, this soulful property has been a gathering place for Parisians since 1925. The 190 guest rooms, which feel like private apartments, are decorated with precious fabrics, paintings, and 18th-century antiques. The on-site attractions include a spa by Le Prairie, a teak-lined pool resembling a yacht, and a courtyard garden fragrant with jasmine. For more than a decade, chef Eric Frechon has held three Michelin stars at Epicure, where menu fixtures include the macaroni stuffed with black truffle and foie gras. Frechon’s culinary dominions are a portal into French gastronomy itself: The hotel has its own chocolate factory, cheese cellar, flour mill, and boulangerie.

Its massive size, centrality to daily life in the capital, and easy accessibility (a Metro station opens up right onto the plaza) makes the Zócalo an ideal place for large-scale temporary exhibits. The government hosts occasional exhibits and makes entry free for residents and visitors alike. Past exhibits have included Gregory Colbert’s “Ashes and Snow,” a show of large-format photos of animals and people, and Willy Souza’s “Mexico en tus sentidos” (“Mexico in your senses”), lush, vivid photos of people and places around Mexico. To see if a show is planned during the time you’ll be visiting, check the website of the Secretary of Tourism.

Most travelers to Istanbul will make a bee line to photograph the blue hues of the hand-painted tiles that give the Blue Mosque its name. Though, for many locals one of the more intriguing mosques to visit is Fatih Mosque, located atop the highest hill of the city. Fatih Mosque is worth a visit for many reasons. Christendom’s Church of the Holy Apostles once stood here for 11 centuries during the reign of the Byzantines. Commissioned in the fourth century by Constantine the Great and reconstructed by Emperor Justinian 200 years later, the revered basilica housed the sarcophagi of the emperors and their consorts, alongside the relics of saints Andrew, Luke, Timothy, John Chrysostom and Gregory the Theologian. The Church of the Holy Apostles was second only in size and importance to Istanbul’s Hagia Sophia (Ayasofya). Whilst the latter is now the top tourist attraction in the city, the Church of the Holy Apostles succumbed to invasions by the Crusaders and Ottomans. When Fatih Sultan Mehmet II (otherwise known as, Fatih the Conqueror) successfully invaded Constantinople in 1453 he ordered the demolition of the dilapidated church to make way for the first Imperial mosque to be built under Ottoman rule. The first Fatih Mosque was completed in 1463, however, an earthquake in 1766 saw the mosque virtually destroyed. For this reason today’s structure dates back to 1771 and features elements of the legendary Imperial Ottoman architectural style fused with elegant Baroque designs of the 18th century. One of the finest examples of the latter can be seen in Fatih the Conqueror’s türbe (tomb), located in the grounds of the mosque. Visits to the mosque are best combined with the neighborhood’s weekly Wednesday street market.

Delight in a week-long journey through France’s Burgundy region, enjoying exclusive tastings, local cuisine, and charming villages.