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Little-known fact: New Orleans was the first place in North America to license pharmacists (starting in 1769, when the city was still under Spanish rule). After Louisiana became a territory, the U.S. governor extended the requirement, also decreeing that pharmacists take a three-hour licensing exam in order to practice. And no wonder illness got such attention—the city was arguably the least healthy place to live on the continent; it was riddled with yellow fever, malaria, and dysentery. This dark but fascinating history is explored in this atmospheric 1822 town house, which was once the home and shop of Louis J. Dufilho, the first licensed pharmacist in the city—and hence in the country. Exhibits include apothecary jars, tools of the trade, and leeches. (Yes. Leeches.)

On most days in Prague, it feels like every tourist in town has gathered on the Charles Bridge. And for good reason — this 14th-century cobblestone span crosses the Vltava River, connecting the Old Town with the Lesser Town (Mala Strana) and providing picturesque views of both sides of the river, medieval churches, towers, and Prague Castle on the hill. King Charles IV commissioned the bridge in 1357. The bridge has 16 arches and protected by towers on either end: the Old Town Bridge Tower in Old Town and the Judith Tower and Lesser Town Bridge Tower on the Mala Strana side. The bridge is lined with 30 large statues of religious figures and luminaries, dating from the Baroque era to the present day The best time to go is at dawn, sunset or after dark after the crowds have thinned and romance is in the air.

Visitors often want to bring a souvenir from San Miguel back to the kids or friends at home...nothing too elaborate, but authentic nonetheless. Head to the three-block Mercado de Artesanías for a leisurely stroll amid the stalls. Start at the west end and work your way east to find silver, crafts, jewelry, pottery…if it fits in a suitcase, you can buy it here. To the east of the artisans’ market, visit the Mercado Ignacio Ramírez, where you’ll find head-high pyramids of fruits and vegetables, perfect for great photos; nightstand-worthy flowers; and food stalls offering everything from custom-made licuados—think smoothies, Mexican style—to peeled cactus leaves freshly prepared for a nopal salad. Good hunting!

Santa Monica has plenty of posh spots, but the best-known might be the Bungalow, a beach-bar-style lounge right across the street from the ocean. There’s a high-ceilinged main bar inside, but the real action happens on the front patio and in the back garden, where patrons can take full advantage of the pleasant L.A. weather. Patio seating is coveted space, but if you can snag one of the funky couches and wooden tables—especially if it’s by a fire pit—you can comfortably spend the rest of the night chatting over cocktails under twinkling lanterns, a cool ocean breeze at your back. A second location in Huntington Beach has vintage interiors and ocean views right on the Pacific Coast Highway.

Just southwest of Astoria, Fort Clatsop replicates the encampment built by Lewis and Clark’s Corps of Discovery soon after they reached the Pacific. From December 1805 to March 1806, they hunted and gathered food, distilled salt, traded with the local tribes and documented their surroundings. The center includes the log fort (staffed by costumed rangers), an exhibit hall, a gift shop and films, plus trailheads for the Fort to Sea Trail and the Netul River Trail.

The name Fred Segal—and especially the logo—encapsulates L.A. style. Since the early 1960s, it’s been where Angelenos shop for their denim-heavy wardrobes and, in more recent history, where such trendsetting SoCal brands as Juicy Couture, J Brand, and True Religion got their start. These classics and many others line the walls of the iconic Melrose shop, but the 2017 opening of a 13,000-square-foot retail space on Sunset Boulevard started a new chapter. Along with its core seasonal collections, the shop holds 10 brand-specific shops-within-shops, along with pop-ups that change from day to day. The result is a space that feels like a high-fashion bazaar. Channel your inner treasure hunter and dig in for a long while—you’ll be rewarded with finds from AMO Denim, Seeker, Hartel, Levi’s, Marie Veronique, CAP Beauty, and Dita Eyewear. The whole selection is carefully curated to give shoppers something unique, whether it’s a vintage Comme des Garçons piece or an entire collection straight from Libertine’s runway. Must-do: Grab a coffee at Fred Segal Café by Tartine (which is so appealing for lunch that it causes an uptick in shoppers around noon each day) and snap a photo in the living room swing, with the entirety of downtown as your backdrop.

Set in a refurbished Victorian hunting lodge on a 26,000-acre estate, Shieldaig Lodge is the epitome of Highland romance. With everything from breathtaking views of Shieldaig Bay to log fires, cozy lounges, and an extensive whisky and gin collection, the hotel offers Scottish hospitality at its finest, surrounded by stunning scenery. Quietly elegant, the 12 guest rooms come furnished with antiques and luxurious touches like Egyptian cotton sheets, goose-down duvets, and homemade shortbread from the hotel’s kitchen. For utter opulence, book the suite, which features a four-poster bed, separate sitting room, and rolltop tub with views of the bay.

At the restaurant, rare-breed lamb, Highland cattle, and deer from the hotel’s estate provide the raw ingredients for the sumptuous menu. Also available are crabs, lobster, langoustines, oysters, and scallops caught by hand right in front of the property, and vegetables grown in the on-site walled garden. After dinner, grab a nightcap in the Liberator Bar, which stocks an ever-growing collection of more than 110 gins and 250 whiskies from around the world. The next day, visit the lodge’s falconry (home to eagles, falcons, hawks, and owls), or have the concierge arrange a local activity, from deerstalking and fly-fishing to hiking, boating, and pony trekking.

A colorful working-class neighborhood near downtown that had fallen on hard times, Woodstock has been revitalized with a mix of galleries, artists’ studios, boutiques, and restaurants. Much of the area’s original vibe remains, however, thanks to the long rows of colonnaded shops that edge Albert and Victoria roads. Among the nearby storefronts that are open throughout the week are Espresso Lab Microroasters and Luke Dale-Roberts’s award-winning restaurant, the Test Kitchen. Continuing down Albert Road, you’ll find spots like the Woodstock Co-op and the very trendy Woodstock Exchange, with a great array of places to eat and stores selling local goods. At the end of Albert Road, there’s a concentration of galleries, including the Stevenson, Goodman, and SMAC. On Saturdays, Woodstock draws crowds to the Neighbourgoods Market, a prepared foods extravaganza in the Old Biscuit Mill.

Mount Pellegrino, which towers over the coast between Palermo and the beach of Mondello, is a popular day excursion from Palermo. The panoramic view from the top is breathtaking. And while you’re up there you can visit the sanctuary of Santa Rosalia, who is believed to have saved Palermo from a plague in the 1600s. She lived in a cave on the mountain until her death around 1160, and more than four centuries later hunters found remains that were thought to be hers. The plague in Palermo ended, it was believed, because her bones were finally given a proper Christian burial. This shrine was built around her cave to protect the site, and Santa Rosalia was named the patron saint of Palermo.

Teenage Mutant Ninja Turtles T-shirts, Members Only jackets, Beavis and Butthead outerwear, Max Headroom sunglasses… oh yes, these are all the droids we’re looking for. Visitors on the hunt for totally tubular leg warmers, an acid-washed jean jacket, and a Michael Jordan bobblehead need look no further than Rad Vintage, supplying all the vintage toys, clothing, videos, and accessories that our inner kids could ever dream about. It’s one of the biggest vintage stores in Andersonville; the merchandise is in spectacular condition, and the prices are reasonable. It’s rad, man.

Belizean cuisine includes a healthy dose of Middle Eastern influence, thanks to the small but established Lebanese community in Belize. If you’re on the hunt for authentic shawarmas, kebabs, hummus, and gyros, the tastiest and most affordable versions you’ll find are at Sahara Grill. The restaurant, across from the Best Western Biltmore, might not look like much from the outside, but that quickly becomes a distant concern once you dig into one of the flavorful platters.

Set on 18 literally green acres, this amenity-rich hotel feels like a secluded retreat among the towering pines, sprawling oaks, and manicured grounds—despite its proximity to the bustling Loop 610 and the Galleria. It affords so much peace and quiet, along with accessibility, that President George H. W. and Barbara Bush used the Houstonian as their home address while he was in office, and stayed on property during visits back to Houston.

The lobby has a warm, luxury lodge feel with soaring ceilings, wood details, and a massive stone fireplace. Guest rooms feel more elegant and traditional, with lavish textures and verdant floor-to-ceiling views. Every room has a 42-inch HDTV, complimentary Wi-Fi, a Keurig coffeemaker, and terrycloth bathrobes. (There are 67 concierge-level rooms that include daily continental breakfast, after-dinner sweets and cordials, plus additional services.) For the nature-minded, there’s a mile-long walking trail around the serene property.

Cruising through Prince Christian Sound, passengers only see one sign of human habitation against the stark landscape: the tiny Inuit village called Aappilattoq, which means “sea anemone” in the local Greenlandic Inuit language. Aappilattoq sits perched at the edge of the water with towering mountains all around, making the village virtually inaccessible by land. The cluster of colorful houses is home to around 100 people, rugged individuals who mostly fish and hunt the harsh terrain as they live isolated from the outside world (except for the occasional arrival of a boat or helicopter).

This beautiful Parisian cemetery is on the Boulevard de Menilmontant and next to the Metro station Philippe August, in the 20th arrondissement. Upon entrance to the main gate, grab a map so not to get too lost. The art work on the memorials and the stories behind the names on the headstones inspire a mood of great tragedy and romance. The locals call it the la cite des morts (the city of the dead). The cemetery makes the ideal place to explore if you’ve seen a lot of Paris before and want to dig a bit deeper. Seek out the tombs of 1) Oscar Wilde (for all of those declarations and kisses left behind); 2) Georges Rodenbach, a Belgian writer and poet of the 19th century with a breathtaking tomb; 3) Victor Noir, who became more famous in death (by duel) than life. Seek the answer to the riddle of why his tomb is seen as good luck for fertility You’ll also see the gravesite of Gertrude Stein and Alice Toklas, buried side by side in a testament to their love. The list of the celebrity dead goes on and includes Gericault, Piaf, Chopin, Heloise and Abelard. Even Jim Morrison. An afternoon here is guaranteed to leave you grateful for the treasures you found but weren’t expecting.

Today, Ketchikan’s Creek Street crawls with visitors hunting for souvenirs among the boardwalk’s shops, but in the early 1920s crowds came here for very different reasons—to visit the speakeasies and brothels. Dolly’s House Museum is located in what was, until 1953, one of the more popular brothels along the creek. Today you can see old photos and memorabilia from that era, including Dolly’s boudoir, complete with a brass bed, an organ with sheet music and a hidden liquor cabinet.