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Little-known fact: New Orleans was the first place in North America to license pharmacists (starting in 1769, when the city was still under Spanish rule). After Louisiana became a territory, the U.S. governor extended the requirement, also decreeing that pharmacists take a three-hour licensing exam in order to practice. And no wonder illness got such attention—the city was arguably the least healthy place to live on the continent; it was riddled with yellow fever, malaria, and dysentery. This dark but fascinating history is explored in this atmospheric 1822 town house, which was once the home and shop of Louis J. Dufilho, the first licensed pharmacist in the city—and hence in the country. Exhibits include apothecary jars, tools of the trade, and leeches. (Yes. Leeches.)

The Riviera Maya’s most beautifully styled adventure park begins with a reception area inside a natural cave. Tours here include Latin America’s highest zip lines over the tropical forest, amphibious vehicles you drive through caves and jungles, and swimming and rafting through underground rivers. Though Xplor is a family-friendly attraction, it may be better suited to teens and adults because of the physical activity required. If you don’t have all day, book Xplor Fuego, the nighttime admission: Temperatures are cooler, torchlight adds an exotic touch, and you soar over the trees by moonlight.

Today, Québec City is decidedly francophone. While 50 percent of Montreal‘s residents describe their mother tongue as only French, the figure is 95 percent for Québec City. This was not always the case, and for much of its history the city had a significant anglophone minority. The Morrin Centre is one reminder of that period. In 1868, the building, which had been used as the town’s jail (the old cells are included on tours of the building), was renovated to become Morrin College, an affiliate of Montréal’s McGill University. It offered instruction in English, though it would be forced to close in 1902 as the number of students interested in an English-language education dwindled. The institution lives on as an English-language cultural center, and book lovers should be sure to visit the elegant library, established the same year as the Morrin Centre by the Literary and Historical Society of Québec, Canada’s first learned society.

Originally laid out during Spanish rule, the Alameda Central was Mexico City’s first municipal park, at one time reserved for the elite. Today it’s a well-manicured garden for all, especially popular with working-class crowds on Sundays. Its willow-lined lanes lead to old-fashioned statuary, fountains, and a gazebo (where something’s always going on), as well as a rotating calendar of contemporary sculpture exhibitions. On the park’s western edge and occupying a beautifully restored art deco structure, the shopping and design center known as Barrio Alameda houses edgy boutiques, a chic guesthouse, and trendy restaurants whose outdoor seating is a people-watcher’s delight. Duck in for a glimpse of how the city center continues along its gentrifying course.

In recent years, this pretty neighborhood, located just five minutes north of downtown Orlando, has become a dining, shopping, and entertainment destination in its own right. Edgewater Drive is lined with restaurants, shops, and offices, while the surrounding residential areas feature historic bungalows, Craftsman-style homes, brick streets, and lakefront views. Favorite eateries in the neighborhood include Jade Sushi & New Asian and K Restaurant, which is nestled in a cute old house. While there isn’t a college nearby, the area gets its moniker from streets named after famed universities like Princeton, Dartmouth, and Harvard.

This dramatic two-tier waterfall, whose name translates as “Golden Falls,” a reference to the shimmering mist that sometimes appears around the falls, is one of Iceland’s most famous—which is saying something in a country abundant with waterfalls. Saved from oblivion during the 1920s (foreign investors wanted to dam the falls to create hydropower), the waterfall lies in a canyon on the Hvítá river and is backed by scenic snowcapped peaks. It’s possible to follow the falls as they flow downstream through the canyon, either via a walking trail or on a rafting trip, though it’s worth noting that the paths are wet and can be slippery. The visitor center has a canteen that serves up surprisingly tasty local dishes like lamb soup; there are also a gift shop and a local exhibition centered around traditional life in the area.

In Rupit, Stone cottages with orangey-red terracotta roofs perch around a stream, half-hidden by the mountainous green hills. An hour and a half drive from Barcelona, walk around this beautiful, if tiny village (approximately 340 residents). Pose for pictures in the dovetailed doorway of the Smithy, and carefully cross its hanging wooden bridge, but remember, it will only support the weight of 10 people at a time. For sweeping views of the village, hike to St. Joan de Fàbregues, a Romanesque building perched on a hill.

Since everything seems bigger in Texas, it’s no surprise that the Texas State Capitol holds the title for largest state capitol building in the union (360,000 square feet of floor space in the main building!). The building is also quite beautiful and houses some historical paintings. The inside of the capitol dome, with a lone star at the apex, is an impressive sight. Stroll the grounds to see fountains, old trees, and sculptures of historical Texas figures. The capitol grounds also offer a great view of downtown to the south and the University of Texas to the north. The Texas landmark is definitely worth a visit on a trip to Austin.

Home to warehouses and bustling trolley stops in the 1920s and ’30s (with the warehouses becoming artists’ studios and storage facilities in the ’70s), these few blocks in South Dallas’s Oak Cliff neighborhood were designated a National Historic Landmark in 199O—right around the time the area was experiencing a decline. In the new millennium, however, there’s been a revival: Today the area’s brick buildings and charming former homes hold over 60 independent shops, restaurants, bars, cafés, and galleries. Grab a coffee or glass of wine and browse the tomes at the Wild Detectives bookstore, shop for furniture and local artwork at Neighborhood, and find unique gifts and design items at Bishop Street Market and We Are 1976. Foodies also flock to top spots like Hattie’s for Southern low-country–inspired fare; the much-acclaimed (and often hard to reserve) Lucia for Italian fine dining; Eno’s Pizza Tavern for thin-crust pies; Tillman’s Roadhouse for Texas- and Southwest-flavored favorites; and the legendary Lockhart Smokehouse for pit BBQ. Save room for artisan sweets from Dude, Sweet Chocolate (which has garnered national acclaim) and a slice of fresh-from-the-oven pie from Emporium, where the menu changes seasonally. With the area now firmly enjoying “features on travel TV shows” status, and private residences still lining the side streets, parking here can be tricky—especially on the weekends, or during a festival or one of the regular wine, art, or jazz nights.

Tempt fate at the Monkey Paw’s Book-O-Matic machine, where for the price of a toonie you’ll be delivered an archaic tome in the vein of Elementary Arabic, Vol. 3. I’ll let you know how my studying gets on. The Monkey’s Paw is an eclectic vintage bookstore on Dundas with a collection of unique books, vintage maps, and bugs preserved in Lucite.

Atop Cap Diamant (Cape Diamond), at the city’s highest point, the Citadelle overlooks Old Québec, the St. Lawrence River, and the Plains of Abraham. There have been defensive structures here as early as the French period—in fact, the location of Québec City was chosen because Samuel de Champlain saw the strategic advantages that Cap Diamant offered. The fortifications you see today, however, date to the 19th century: They were built after a failed attempt by Americans to conquer Québec City during the War of 1812. Students of World War II history may be familiar with the Citadelle as the site of the Québec Conferences, when Winston Churchill, Franklin Delano Roosevelt, and Canada‘s prime minister, William Lyon Mackenzie King, met to plan their countries’ strategies during the war. The Citadelle is still an active military base; the museum inside is devoted to the 22nd Regiment, which makes its headquarters here.

It’s an unforgettable experience: Getting up at the crack of dawn in mid-winter, walking through the large municipal park on the Pest side of town, checking in to the Széchenyi Thermal Bath (mostly with Hungarian pensioners because tourists usually arrive later), and slowly easing into one of its three large outdoor hot spring pools, surrounded by the golden yellow neo-Baroque palace—built in 1913 for the baths—while old men playing chess in the water. Then watch as the sun rises slowly, and your breath dissipates into the cold, crisp air. The spa has 15 indoor baths, too, as well as 10 saunas at various temperatures. This spa isn’t about being posh, it’s about easing into the kind of everyday self-care that Hungarians have known and avidly practiced for centuries. Just join them.

With all of Orlando’s man-made attractions, it’s refreshing to get deep into nature at this wonderful state park, located north of downtown and the theme-park corridor. Spread across 7,000 acres of pristine central Florida forest, the park centers around the headwaters of the Wekiwa River, a beautiful, blue-and-green-hued spring with a roped-off area that’s safe for swimming (alligators do dwell in the main river). Rent a kayak or canoe at the park and paddle from the spring into the river, where you can spot turtles and alligators sitting on the banks. If you’re seeking a more primitive experience, you can also book one of the park’s spacious campsites, some of which come with hookups for electricity and water.

At Luma on Park, James Beard Award semifinalist Brandon McGlamery works magic with a modern American menu. While the restaurant follows dining trends with handcrafted cocktails and small plates, it’s really more of a modernized steak house, with dishes like Harris Ranch short ribs, foie gras terrine, cobia ceviche, and classic wedge salad. For a night to remember, request an outdoor table and enjoy the prix-fixe menu alongside some of Orlando’s best people-watching.