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Painted by Michelangelo between 1508 and 1512, the frescoes on the Sistine Chapel ceiling are considered some of the finest art ever produced. These religious paintings include nine scenes from the Book of Genesis, of which The Creation of Adam is undoubtedly the most iconic.

Whether you’re a fan of awe-inspiring dinosaur skeletons & dioramas, or 19th century European painting, the Carnegie Museums of Pittsburgh have you more than covered. The Carnegie Museum of Natural History is a great place to learn about the history and development of life and human cultures, while the Carnegie Museum of Art offers a broad spectrum of collections, including contemporary art, photography, decorative arts and design, and the Heinz Architectural Center. The best part is, admission to one buys you admission to both, so you can indulge your interests in the Jurassic period and Impressionism in one go.

As the name suggests, you can shout your order from the sidewalk and by the time you get to the counter, they’ve already served up your empanadas. Try the time-tested caldo mayo, a house-specialty beef broth that’s a perfect hangover remedy, especially with spicy salsa de ají, or hot pepper salsa, on top. Members of the Chilean judiciary are often seen here having a tintito, a dainty glass of red wine, before beginning the day’s proceedings. El Rapido opened in the thirties and has been operating ever since—don’t miss this quaint and tasty bit of history.

Since few areas within the city of Venice afford high perspectives of the entire city, take the elevator (no stairs) to the top of San Marco’s Campanile in Piazza San Marco. You may have to put up with a few elbows to get a spot against the railing, but it is all worth it for the spectacular panoramic views of Venice and the lagoon. While here, contemplate the history of this spectacular bell tower and observe the view from the same spot where numerous doges have stood, as well as Galileo. It was here that he introduced his telescope to the doge!

Hawaiians once lived in harmony with the land: farming, fishing, and harvesting fruit. Today, the state imports 80 to 90 percent of its food. Visit Kaloko-Honokōhau to catch a glimpse of the Big Island’s ancient agricultural traditions, which residents are working hard to revitalize. The park’s landscape of rugged rock contains more than 200 archaeological sites, ranging from fishponds and elevated planters to petroglyphs, lava-tube shelters, and hōlua (toboggan-like slides). Watch for native species like the fragrant pua pilo flower and the endangered Hawaiian stilt, a subspecies of the black-necked stilt. A sugar-white beach stretches north from Honokōhau’s boat harbor and often attracts sea turtles.

This 1st-century wonder will take your breath away. Not only is it one of the city’s most ancient sites, it’s been in continuous use for centuries. Originally built as a private temple, today it is a Catholic church and the resting place of Italian kings and the artist Raphael. Make the most of a wet day in Rome and watch as the rain falls through the center oculus.

One of the great things about the Caribbean is that its rich history was often written at beautiful, easily accessible locations. One of the best places to learn a bit of that history is pictured above. That’s the beach at Columbus Landing in my home island of St. Croix. It was here, in 1493, that Columbus sent ashore a small contingent of his men to scout for fresh water. What they found instead were a group of Indians who weren’t too keen on visitors. What’s the whole story of Columbus and his less than stellar (to say the least) track record throughout the region? That may take a bit more book learning, but feeling what these new visitors may have felt coming ashore in this corner of paradise starts on these sands.

Pictured above is the home of Dr. William LeRoy, a well-known physician in the Lombard area back in the 1800s. Dr. LeRoy specialized in making prosthetic limbs for veterans of the Civil War and lived in this very home from 1881 until 1900. The structure has since become known as ‘The Little Orphan Annie House,’ since the comic’s creator, Harold Gray, lived here when he dreamed up his storyline in the study. For more information about gaining entrance to this historical site, contact the Lombard Historical Museum at (630) 629-1885.

Wandering down the small via S. Chiara I spotted this shop that makes vestments for the Pope. I was tempted to go in and order a pair of red shoes but thought better of it. Since 1798 the Gammarelli family have been outfitting popes, bishops and cardinals. In 2000, Gammarelli was included in the list of Rome‘s historic shops, and is probably the most ancient shop in Rome, still managed by direct descendants of the founder. They have an online catalogue where you can learn all about ecclesiastical vestments. Take a walk by and peek into this historic shop.

Dornier’s modern cellar and production facility is quite different from the traditional 18th- and 19th-century buildings you’ll see in the winelands. For example, a pool above the cellar regulates the temperature of the wines in an eco-friendly way. Its reflective surface also helps keep the entire subterranean building cool. The cellar’s overall design pays homage to the Dornier family’s history in the aviation industry. Contact the winery in advance to arrange a tour of the facility, then enjoy a tasting of award-winning wines like the Dornier Donatus White (a blend of chenin blanc and rich sémillon), the Dornier Merlot (with hints of plum, mint, and roasted nuts), and the Cocoa Hill Sauvignon Blanc (featuring notes of mulberry, roasted oak, vanilla, and spice).

Upon first glance, Circa Las Vegas revolves around sports betting: There’s a three-story sports book in the on-site casino and the pool deck features giant TV screens on one side and tiered, stadium-style pools and lounge chairs on the other. But the first new casino Downtown in more than 50 years also celebrates Vegas history: The design harkens back to Old Vegas dramatics, with art deco lighting in the high-limit areas of the casino and images of old-school gamblers inside the elevators. Owner Derek Stevens has even given a new permanent home to Vegas Vickie, a two-story neon kicking cowgirl who once graced the nearby stretch of Fremont Street known as “Glitter Gulch.” Vickie presides over an open foyer, seemingly nodding at guests as they wander around the casino.

Guest rooms at Circa—512 in all—have dark wood accents and carpets with geometric art deco motifs. Rooms in the Flex King category are equipped with king-size beds and couches that disappear when a second Murphy-style bed is pulled down from the wall. (Travelers who value selfies swear by the floor-length mirrors flanked by Green Room–style lighting.) Floor-to-ceiling windows offer epic views of either Stadium Swim or the Fremont Street Experience, a covered pedestrian walkway that forms the cultural and entertainment center of Downtown and was the main drag in the Vegas of yesteryear until the destination expanded with mega resorts to the south. The hotel also is a short walk from the unmissable Mob Museum, which offers a peek into the history of organized crime and runs a moodily lit speakeasy bar in the basement.

Related: 7 Hotels to Book for “Non-Vegas” People

Tourism is down, prices are up, social services are disappearing, and the government is bankrupt. Which means it’s a good time to get to know Seychelles.

Driving down an old dusty dirt road near Vila Verde da Raia in the area of Tras-os-Montes in northern Portugal I could imagine the area in the 19th or 20th century.The region probably hasn’t changed very much. I have seen pictures of this road from the 1940’s and I can’t see any difference. The road was not paved then and still isn’t. There are no modern homes or strip malls. I loved the natural vegetation and the peaceful vista. After following the road for about 10 minutes, it curved to the right.There were huge sycamore trees on both sides of the road leading into a tiny tucked away village that dates back about 1,000 years or so. The village of Vilarinho had a small plaza and a well. There was a post office on one side of the square, a beautifully restored church ( I wished that I could have seen the original), and many whitewashed granite and concrete homes. I saw that most homes featured modernized interiors. Past the church was the cemetery and large fields of many crops. At first, the residents were very curious but warmed up and became very friendly offering stories of the village, the farming, and tales of the relatives buried in the cemetery. As I walked the village and farm grounds they kept their eyes on this “stranger”, but they were very happy when I expressed such interest in their lives, homes, and their lovely village. A side trip is always a travel bonus and is one of the rewards of going off on your own to mix with the locals.

Perched on a steep hill in the lovely neighborhood of Alfama, you will in no doubt leave with a great souvenir or gift. Sellers throw down blankets or rugs in rows and sell a variety of hand-made goods, antiques, books, clothes, military objects, etc. I took home two wonderful brass bottle openers and a couple of old world maps. Getting to the market is easy and the trip there is quite beautiful; take the Tram 28, or Tram 12 up the hill through the tight, and narrow neighborhood streets (becos). After you’ve spent all of your Euro, take a short walk over to the Santa Engracia Church, Museum of Decorative Arts, or the National Pantheon. Oh, and don’t forget to take in the views and snap a few pictures.

Once a separate municipality, San Ángel—in the city’s south, nestled into its western foothills—is a leafy, genteel enclave whose relative isolation adds a soigné feel (for better or worse) you won’t find in neighboring Coyoacán. Ground zero for promenading is quaint Plaza San Jacinto, whose cute parish church (and beautiful cloister garden) is a sort of spiritual last stand amid the surrounding area’s high-toned consumerism. That said, the plaza’s true spirit comes alive Saturdays, at the so-called Bazar Sábado, an artisanal market that fills the area with stall after stall of handmade jewelry, textiles, crafts, and accessories, plus a great deal of art—some finer, some less so—in styles that go from hippie to haute. Strolling musicians and performers add to the carnival atmosphere.