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Like a nautical version of the yellow brick road, illuminated anchors embedded in the floors of Ironside Fish & Oyster lead you to the Emerald City of raw bars, where the bounteous platters come in Big, Bigger, Biggest, and Holy Sh*t. This last assortment might include, say, 24 oysters, 14 shrimp, 14 mussels, two pounds of lobster, two ounces of sustainable royal white sturgeon caviar, a portion of rockfish ceviche, and some kanpachi crudo for good measure (the mix changes daily according to what’s fresh). Not that lovers of cooked seafood will go hungry at chef Jason McLeod’s Little Italy hot spot, where the catch of the day is a perennial favorite. There’s even a small yet mighty vegetarian lineup (think charred broccolini with dried chilis, garlic, and parmesan; and Japanese sweet potato with scallion chimichurri and puffed quinoa). It’s all rounded out by an impressive bar, where 11 categories of whiskey are represented. While the menu occasionally diverges from the strictly seafaring, the decor never does. The interior design features prow figureheads turned lighting fixtures and artful stacks of steamer trunks.

Opened by Carlo Ritz in 1894, the St. Regis belongs to a particular category of five-star hotels in Rome in which Old World glamour is alive and well. While the current trend in town is toward boutique hotels and converted townhouses, the St. Regis is palatial and uncompromisingly opulent. In the century (plus) since opening its doors on the crest of the Quirinal hill, the hotel has remained a beacon of luxury, and indeed many of the hotels on the nearby Via Veneto, Rome’s luxury hotel row, take their cues from this long-established pioneer.

The entrance through the marble portico just off Piazza della Repubblica leads directly into a grand salon furnished with overstuffed chairs, chandeliers, and antiques. The grandeur continues in the rooms, where classic style and sophistication reign. Owing to its elite clientele, the hotel’s 23 suites come with 24-hour butler service, while the aficionado program is designed to provide exclusive access to sites and special experiences including road trips designed by the Ferrari racing team or helicopter rides to wine estates.

Controlled by the François Pinault Foundation, the same trust in charge of Christie’s auction house, this is a museum-worthy gallery in the heart of Venice. Set inside a 17th-century customs house, it showcases Pinault’s impressive private collection, comprised of some 2,500 pieces of modern art. The location, at the point of land where the Grand Canal meets the Giudecca Canal, is equally spectacular. After you’ve finished browsing the art collection, grab a pastry or a small bite at the in-house Dogana Cafe.

With amazingly clear emerald waters, the calm sea off of Santa Margherita and Portofino is perfect for snorkeling and scuba diving (May-September is the best season, although it has been known to stretch!). Il Grande Blu provides all you need to enjoy the waters - instructors, equipment, even towels! And if you prefer to stay on top of the water, they have kayaks for rent, as well as a beautiful full-service beach. (If you are up for even more of an adventure - head even further around the bay to San Fruttuoso to scuba dive - there is a sunken Christ figure just a few meters out into the bay that is really gorgeous to view up close!)

The tiny Abbey of San Fruttuoso is nestled in a cove between Camogli and Portofino, and accessible solely by foot or boat. If you want to hike it, find the trail at the far end of Camogli, and be ready for a steep, but gorgeous, two hour hike up and over the mountain. If you would prefer a quick 15 minute boat ride, catch the boat for a few euro in the harbor of Camogli and ride to San Fruttuoso in style. The abbey itself is beautiful, but it is also nice to simply sit and have a cocktail at the beachside restaurant (look closely - their kitchen is upstairs, so they send the food down in a small wicker basket when it’s ready!).

During my last stay in Florence, I wanted to learn more about the artisan trades, and Bruscoli was recommended to me by a local. I am so glad it was. As I walked along the Arno River on my way to the workshop, I had no idea what an extraordinary little slice of Florence’s history I was about to witness. At Bruscoli, you can learn about the artisan heritage of Florence from Paulo Bruscoli, a fourth generation craftsman and owner of a small shop that sells both Florentine paper and leather products engraved with gold leaf. From stories of the bookbinding tradition in his family and the great flood of 1966 to his extensive collection of traditional engraving tools, the details housed in this small shop bring to life a tradition deeply rooted in Florence’s heritage yet unlikely to continue in the future. Bruscoli is an easy walk from the city center. High-quality leather and paper products are for sale, but Paulo Bruscoli specializes in personalized items, which you can order and pick up later or have sent to you. Mr. Bruscoli speaks English.

A 2010 renovation transformed a traditional lodge into a 12-room inn that’s both cutting- edge and cozy. Built by the former Olympic skier Gerardo Mussner in 1963, the hotel is now run by Gerardo’s daughters. His wife, Helga, serves South Tirolean dishes such as almond-crusted venison. In 2010, the hotel was reimagined with larch wood, glass, and local stones that match the mountains. The curved roof stands out against the peaks. A 758-mile network of 12 ski areas, Dolomiti Superski is just five minutes away. The closest section, Val Gardena, hosts two Alpine Ski World Cup events in December. From $2,284 per week. 39/471-795-274. This appeared in the November/December 2012 issue.

The English novelist D.H. Lawrence came to New Mexico to recuperate after being diagnosed with tuberculosis. This 160-acre ranch, gifted to him by Mabel Dodge Luhan, is where he started work on his novel The Plumed Serpent. He wrote underneath a tall ponderosa pine, immortalized by Georgia O’Keeffe in her painting The Lawrence Tree. Take a tour of Lawrence’s estate, including the famous tree, “standing still and unconcerned and alive,” as Lawrence once wrote.—By Edmund Vallance

Wealthy New York heiress Mable Dodge Luhan was a lifelong patron of the arts. D.H. Lawrence and Georgia O’Keeffe were among many artists and writers invited to stay at her house in Taos. These days, the picture-perfect adobe lodge (built in 1918) operates as a bed and breakfast-cum-art retreat. Hone your painting skills on a five-day course or bed down in “The O’Keefe Room” on the second floor, where Georgia slept during her frequent visits. —By Edmund Vallance

Within Miami‘s most famed Fontainebleau Hotel is an gastronomic superpower, but it’s the mixology by bartender Hector Aceveda that really sets the eatery apart. Try some of the innovative cocktails using food products and specialty preparation. A great alternative to the pool bars and nightclubs.

This former royal palace is one of the largest museums in the world, and its art collection is considered one of the most comprehensive. It contains around 400,000 works, although—mercifully, perhaps—not all are on display at any one time. There are some pieces that never get taken off the walls. The Mona Lisa and her smile attract millions of visitors each year. Other must-see masterpieces include the sculptures Winged Victory of Samothrace and Michelangelo’s Rebellious Slave, and the Eugène Delacroix painting The Death of Sardanapalus. There’s no real trick to avoiding crowds at the always-packed museum. The best you can do is try to go in the off-season, early or late in the day, and on a weekday. Your chances of being alone with the Mona Lisa will still be slim to none, but you might be able to actually see that enigmatic smile behind the Plexiglas.

Black Rock Lodge is the ultimate Belizean jungle lodge, located a few miles outside San Ignacio and down a dirt road that leads you into a high-walled, karstic river valley. All the cabinas are perched on the hillside with spectacular river views and wildlife viewing opportunities from the front porch. The main dining area offers more opportunities to spot birds and monkeys on the opposing hillside or watch intrepid guests go over the waterfall on an inner tube directly below. The lodge is a great place to base yourself for a range of activities and sights, such as Maya ruins, cave exploration, canoeing and rafting, hiking and bird watching.

Tlacolula is the largest town in the Eastern arm of the Oaxaca valley. Market day in this town is on Sundays and on this one day of the week hordes of people come to town from nearby villages to buy, sell, and socialize. You’ll find all kinds of goods for sale, from produce to live poultry to electronics. Block after city block is closed to traffic and vendors occupy both sides of the street, while shoppers and ambulant vendors fill the space between them. Tarps suspended by ropes overhead provide shade, but you will need to watch where you’re going, and duck occasionally to avoid walking into a tarp or rope. There are some specialties you should be sure to check out in the Tlacolula market. The food stands selling “barbacoa” are very popular here. This meat - either lamb or goat - is cooked in an underground pit and you buy it by weight. The bread made in Tlacolula is very good; there are a few types that are particular to this area, but one that you should definitely try is the “pan de cazuela.” It has a swirl of chocolate and raisins in it; when it’s really fresh it’s absolutely delectable.

This unassuming adobe house in Santa Fe is home to one of the world’s ‘top ten places’ to drink chocolate. (Seriously. It ranks up there with anything in Europe or South America.) Walk the few blocks from the city’s central Plaza, open the door and inhale the pre-columbian fragrance of the eight or nine ‘drinking elixirs’ that will be swirling and ready to serve. Free samples will tempt and educate you... My wife lingered over the “Spanish” blend, sipping on a blend of chocolate, floral essence, coconut sugar and spices, while I had their version of “atole,” a traditional hearty breakfast drink made with blue corn masa, chocolate, honey, Mexican vanilla, and local chimayó chile pepper. But there’s more to cacao here than just drinking; the handmade truffles, caramels and mendiants are arrestingly good! The house-made agave caramels dusted with chile powder (again, from the beloved chimayó peppers from their namesake valley just north of the city) or topped with nuts from the pinyon pines so common in the foothills of the Sangre de Cristo mountains--these are treats with a definite taste-of-place. Sip. Savor. Linger. Marvel.

With two hiking trails ascending 1,280 feet to its peak, Camelback Mountain is a great option for nature-fiends who like a challenge. Both the Echo Canyon and Cholla trails exceed a mile in length and are accented with steep grades. Average hiking times range from 1.5 to 3 hours round-trip, so pack accordingly and bring enough water.