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Foodies (and those simply interested in local color and a good meal) should head to San Lorenzo and its covered Mercato Centrale. Florence’s main market for edibles is housed in a 19th-century glass-and-iron building. On the ground floor, delis, stands, and butcher counters sell a fantastic array of local fruit and vegetables, cheeses, dried porcini mushrooms, baked goods, balsamic vinegars, and olive oils plus fresh fish, poultry, and meat. Upstairs, a modern food hall has opened: Stalls sell prepared foods and meals for happy and immediate consumption at a central seating area.

Built atop a west-facing cliff, Doca Do Cavacas is the best waterfront restaurant in Funchal for views of Madeira’s spectacular sunsets. There is nothing fancy about this place—it serves simple, down-to-earth grilled fish and seafood. For some locals, this is the top spot for limpet clams and bolo do caco bread.

Famous for bringing the world the likes of Arrogant Bastard Ale, Stone Brewing is nothing if not cheeky. This is, after all, the first American craft brewer bold enough to open an outpost in Germany, a country steeped in beer-making tradition. But Stone’s audacity is hardly unfounded, as you’ll discover when you visit the company’s headquarters in Escondido—ideally, for a private tour and tasting. If you’re not already a fan of San Diego’s particularly hoppy style of IPAs, there will be at least one beer on tap that makes you a convert. But first, you’ll walk through the brew house—past mash kettles and whirlpools and fermenters—to learn all kinds of fun facts, whether it’s the surprise source of the chocolaty notes in Stone’s porters and stouts (mega-roasted malted barley) or what the upcycling options are for spent grains (cow feed and dog bones). Pro tip: After your tour, bypass the lovely indoor restaurant for the even lovelier outdoor gardens—all bamboo and koi ponds and hummingbirds. Sit back in an Adirondack chair with a beer (try one of the extra-innovative brews on offer only here) and warm pretzels with Stone Ripper Pale Ale beer cheese sauce.

Step inside the Eye Film Institute to discover an homage to international cinema replete with interactive displays and perched like an ivory spaceship ready for launch on the northern bank of the IJ River. The striking facility, accessible via a free ferry from the main train station, houses four movie-screening rooms, a museum shop, and an exhibit space showcasing the works of masters like Fellini and Kubrick. Topping the contemporary structure is the eye-popping Eye Bar-Restaurant, where you can wash down a plate of bitterballen with beer on tap while musing about cinematography. On sunny days, a spacious terrace beckons.

Could there be a more glorious setting for a cheese’s origin? These pastures surrounding a hilltop village (Gruyères) crowned with a castle (the Château de Gruyères), happy Swiss cows grazing with views of the Alps all around, producing the milk which, in time, arrives on grocery shelves as cheese around the world, stamped ‘GRUYÈRE’...and there’s a geometric garden in the castle’s courtyard, too.

The Ponte dei Sospiri was given its English name by part-time Venice resident Lord Byron, who wrote in Childe Harold’s Pilgrimage: “I stood in Venice on a Bridge of Sighs, a palace and a prison on each hand.” Byron’s travelogue nails it: When you stand on the famous crossing, the Doge’s Palace and a public prison are on either side. A local myth (that turned into the plot line for the film A Little Romance) says that lovers who kiss on a gondola at sunset beneath the Bridge of Sighs will be granted eternal love. Access to the bridge itself is through the Secret Itinerary tour of the Doge’s Palace.

This shop took over one of Los Angeles’s most iconic buildings when it opened in 2012—the art deco–styled former headquarters of business magnate Howard Hughes. But Just One Eye’s pioneering founder, Paola Russo, has managed to put her own original stamp on the space. The luxury concept store is arranged like a gallery, showcasing rare and one-of-a-kind editions of clothing, jewelry, vintage furniture, and contemporary works by such artists as Takashi Murakami. Finds range from crocodile backpacks designed in collaboration with the Row and artist Damien Hirst to a survival kit created with input from the Navy Seals. Over the years, Just One Eye has grown and evolved with shops-in-shops. Installations may feature gowns by Alexandre Vauthier—French haute couture designs sold since the store’s beginning—or Daniela Villegas’s playful jewelry inspired by nature. Somehow both intimate and grand, the eclectic boutique is decidedly gallery-like, but approachable, too. Knowledgeable staff act almost as docents, guiding customers one-on-one and offering them coffee. Insiders’ tip: Valet parking is complimentary, helping to assuage any guilt over splurging on that Gucci bag.

Together with the Portas da Cidade (the arched gates to the city), St. Sebastian’s Mother Church is Ponta Delgada’s most iconic example of Azorean white walls with black basalt trim. Built in 1547 and refurbished through the years, it reflects the changes of styles in Portuguese church architecture. Manueline, Baroque and Gothic are its main influences, with the altar of carved and gilded wood being the center of attention.

Vietnamese love the cool climes of this town 5,000 feet above sea level in the highlands of southern Vietnam. Da Lat was “discovered” as a site for a potential town in 1893 by French bacteriologist Alexandre Yersin; before long, it was established as a refuge where French Indochina’s colonial administrators living in Saigon could cool off during their downtime. French villas—many still standing today—and summer palaces of Vietnam’s last emperor, Bao Dai, soon followed. Today many visitors still come to escape the tropical heat typical of most of the country, wander round the man-made lake in the heart of town, and enjoy the locally grown fruits and vegetables sold at the morning market—strawberries, peaches, avocados, artichokes, and more. The Hang Nga guesthouse here is a small hotel with an unusual surrealist design. Da Lat is also a great destination for adventure travel, with outfitters offering mountain-biking, kayaking, white-water-rafting, and canyoning excursions; Phat Tire Ventures is the best operation in town.

You will likely see Bronzino’s famous portrait of Eleonora (or Eleanor) de Toledo, in the Uffizi, during your visit to Florence. The Spanish noblewoman who became the duchess of Florence in 1539 when she married Cosimo I de’ Medici was unusual for her time, playing an active role in politics and as a patron of the arts. Her patronage extended to garden design, in its infancy (at least in Europe) in the 16th century. Eleonora commissioned the Boboli Gardens behind the Pitti Palace as a green escape from the city; they continue to provide a retreat for travelers today.

Among the earliest examples of the formal compositions that would dominate garden design through the 20th century, the grounds are dotted with classical statues and fountains while straight axes run up and down the hillside with an apparent disregard for topography. A moment in design history can be experienced first hand here. There’s a feeling that the man who planned the gardens (Niccolò Tribolo) conceived a formal plan and then simply laid it atop the site. Principles of garden design were later to shape city planning. The allées of the Boboli Gardens were early models for grand boulevards leading the eye to distant monuments. One of the pleasures of gardens, however, is that you don’t need to know their histories to enjoy the flowers in bloom or the sounds of birdsong and splashing fountains.

Located a few steps away from the Ponte Vecchio in what was at one time a medieval palace, this restaurant serves a traditional menu of dishes made with regional ingredients. Their beef is sourced from a farm in the Maremma countryside and the wine list highlights Tuscan producers. Even the restaurant’s name is a nod to the local culture—orafo means “goldsmith,” and this neighborhood was where gold workshops were once located. Start with Tuscan white beans drizzled with olive oil, with a serving of fennel salami, then move on to the pasta course. (The taglierini ai piselli freschi, pasta with fresh peas, is particularly good in season.) For dessert, try the pear slow-cooked in wine or cantucci cookies dipped into vin santo, a strong sweet wine.

Up until 2004, Switzerland’s iconic furry friends—St. Bernard dogs—were bred at this monastery and hospice. While the canines have been relocated, the Great St. Bernard Hospice, which sits on a barren, treeless plane at 8,100 feet, is still an active monastery run by Augustinian monks. The steep four-mile ascent from the valley is a killer on foot, but still doable—on groomed trails in summer and on snowshoes in winter. Inside, monks greet you and show you to communal tables in the stone dining hall where vegetable soups are served with hunks of Bagnes cheese, thick slices of brown bread, and honey-sweetened tea (or a carafe of red Dôle wine produced in the Valais region just below, which seems to be the more popular option). Don’t miss the odd museum, displaying local taxidermy, ancient coins, and maps once used for Alpine crossings; the 800-year-old crypt is allegedly stuffed with the bodies of ancient travelers who didn’t survive the journey. A register of “Les passants célèbres” includes Charlemagne, Napoleon, and Alexandré Dumas but omits Charles Dickens, who lived nearby for a summer.

For some truly luxurious pampering, look no further than The Spa at the Four Seasons Resort The Biltmore Santa Barbara. The 12,000-square-foot space sits between the rose garden and the Jungle Pool with 11 treatment rooms and uninterrupted views of the Pacific Ocean and Channel Islands. The Grape de Vine is one of the spa’s four signature 80-minute treatments, and it begins with a exfoliation using a grape-seed body scrub, followed by a full body massage with rose and lavender essential oils. Spend the day using the sauna, steam room, or pool, or zone out the upper level relaxaton room. Special treatments for teens are also available.

Adjacent to the restaurant is a cheery boutique filled with gourmet products from all over Tuscany. Thanks to the restaurant’s long-standing relationships with many of the region’s top purveyors, you’ll find high-quality olive oil (tastings can also be arranged), cheeses, cured meat, preserves, breads, and more. Not all of it will make it through customs, but you can savor any perishables on a picnic to the Tuscan countryside.

Because of its unique climate and volcanic soil, markets in the Azores feature exotic produce not found anywhere else in Portugal. Annonas (similar to pawpaw or custard apples), araçal (somewhat like guava), yam, peppers and the ever-present sweet pineapple can all be found at this market. More local bounty can be found at Rei dos Queijos, a fromagerie that sells cheeses from the nine islands.