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Elevate the normally mundane experience of shopping for medicine-cabinet basics like soap and toothpaste with a visit to one of the oldest pharmacies in the world. In this 13th-century chapel with early Renaissance frescoes, Gothic carved wooden cabinets, and crystal chandeliers, most items are still crafted according to formulas originally created by Dominican monks. A small museum displays equipment once used to make Santa Maria Novella products, as well as a collection of beautifully painted ceramic jars that held the herbs and powders. Linger a little longer in this fragrant world by ordering a pot of herbal tea or a small glass of one of the historic liqueurs in the tearoom.

Oaxaca has no shortage of gorgeous colonial-era buildings; in fact, that’s what draws many visitors to this stunningly beautiful Mexican city. But Casa de Siete Balcones, a seven-room boutique hotel, is particularly special, with unusually spacious rooms and, as its name suggests, seven balconies (yes, one for each room). The building itself dates to the 18^th century. The structure, along with the rooms’ heavy wood furniture and the cobbled street just outside the door, has the effect of transporting guests to another era. Other design details that will appeal to visitors with nostalgia for an earlier century include Spanish tile floors, and a courtyard filled with plants and flowers; the Spanish-style patio also features a bubbling fountain. Rooms are filled with natural light, and service is friendly and attentive.

Giovanni di Piero Antinori became a member of the Florentine Winemakers Guild in 1385—and his descendants have been in the business ever since. Today, the company is overseen by Marchese Piero Antinori—the 25th generation of the titled family—and his three daughters, all of whom were involved in the seven-year project to build this stunning winery and visitors’ center. With a contemporary design crafted with materials like wood, terra cotta, and weathered steel, and featuring views out onto vineyards lush with classic Chianti grapes, the center houses a museum and art gallery, winery and cellar, shop, and rooftop restaurant serving gourmet pairing menus. Four different types of tours are available, ranging from general overviews tailored to the first-time guest (and including tastings of three signature wines), to more in-depth cellar visits (with upgraded cru tastings) and tailor-made experience for connoisseurs.

The immense Gothic Cathedral of Seville was built on the site of an ancient Muslim mosque. It was completed in the early 16th century and was designated a Roman Catholic cathedral. Since 1987, this cathedral has been a UNESCO World Heritage Site and is said to be the third largest in Europe. The Cathedral of Saint Mary of the Sea is also the final resting place of Christopher Columbus since 1898. His tomb is large and elaborate. The beauty and size of the cathedral is simply amazing. The exterior is ornate with extensive carvings, there are many doors, flying buttresses, and towers. There are several ornate doors to the cathedral. The one in the photo is the Puerta de Palos. The interior is incredible with extensive gilding. The central nave is lavishly decorated and carved. The main altarpiece is a stunning golden work of art. The floors are polished marble, the columns and arches tall and imposing. There are intricate 15th century stained glass windows. There are 80 chapels in Saint Mary of the Sea Cathedral there in Seville. The beauty and the sheer size of this historic, religious site was quite amazing. I could have spent four or five hours in this incredible monument. The history lesson learned was that of the story of Seville from the 12th century until modern times. You might want to tour with the audio guide. Plan at least two hours. For info: www.travelinginspain.com

Scaling Mount Kenya, the country’s highest and the continent’s second-highest mountain, is on the bucket list of many adventurers. The jagged summit peaks, sharp cliffs, and snowcapped crags can be seen on the northern road from Nairobi when the mountain is not shrouded in clouds. Hiking this monster usually takes from three to seven days, depending on fitness levels. Of the different possible routes up, the popular Chogoria route passes through lush green pastures and by icy blue lakes, crossing dusty martian landscapes along the way. The highest point hikers can reach without specialized climbing equipment is Lenana, more than 16,000 feet above sea level.

If visiting a miniature version of a country the size of a postage stamp makes no sense to you, stay away from Madurodam, a top tourist attraction in Den Haag featuring historic Dutch towns, ports, canals, roads and monuments re-created on a 1/25 scale. On the other hand, if you fancy learning about the history of a nation that would be underwater were it not for Dutch ingenuity, by all means visit this interactive park that tells the story behind the battle against water, as well as many historic venues that still exist in Holland today.

On sunny days, Parisians head for the Luxembourg Garden, built by Marie de’ Medici in 1611 and modeled after the Boboli Gardens in her native Florence. In addition to the magnificent Medici Fountain, there are more than 100 statues arranged around the garden’s 20 hectares (50 acres), which encompass both formal French and English gardens. Here you’ll find chess players, puppeteers, children sailing tiny boats on the octagonal pool and sometimes a free concert in the gazebo.

A 1901 landmark in Hanoi’s French Quarter, the colonial-style Sofitel Legend Metropole has long been a celebrity magnet, welcoming presidents, ambassadors, and literary and cinematic royalty into its marble lobby. Somerset Maugham and Graham Greene both wrote books here (The Gentleman in the Parlour and The Quiet American, respectively); Charlie Chaplin and Paulette Goddard celebrated their honeymoon at the property; and Jane Fonda and Joan Baez took to the bomb shelter beneath the hotel during air raids (book the complementary Path of History Tour, held every day at 5 and 6 p.m., for a chance to see where they hid out).

The 364 guest rooms are divided between two wings: The historic Metropole section has decor shaped by French architecture and Vietnamese culture (think wood floors, louver windows, bird-cage lampshades, and porcelain light fixtures); the newer wing, opened in 1996 just across the traffic circle from the Opera House, has a strong Neoclassical edge with rooms in dramatic red, black, and white. With its green awning, filigree ironwork, and outdoor wood-deck seating, La Terrasse has the feel of a Parisian café, while Le Beaulieu restaurant serves classic French fare and a decadent Sunday brunch. Spices Garden showcases Vietnamese flavors, and three drinking dens—sleek Angelina, gentlemanly Le Club Bar, and poolside Bamboo Bar—appeal to every kind of spirits lover. Between the central courtyard garden and the pool sit the SoFit gym and Le Spa, with eight rooms for soothing East-meets-West treatments.

Once upon a time Lund was one of the most important towns in Denmark. These days, it’s one of the most charming towns in Sweden with its cobbled streets, flower-filled parks, and medieval buildings. Towering over everything is the Lund Cathedral, a Romanesque cathedral which was consecrated in 1145 and includes a huge astronomical clock created around 1380.

It wasn’t until 1658 that the region, Skåne, became part of Sweden. Visitors can descend into the crypt, where the most popular attraction is a column bearing a sculpture of Finn, a giant who reportedly helped build the cathedral.

Light and color are two words that best describe Casa de Las Bugambilias, or House of the Bougainvillea, a bed-and-breakfast inn in Oaxaca’s Centro neighborhood. Every bit of the house, inside and out, is vibrant, thanks to vividly-hued textiles, locally-made artwork and crafts, and, of course, bougainvillea. Guests are treated to a two-course breakfast each morning, with most fruits and vegetables coming from local producers who farm organically and value the fair-trade model. Service is exceptional, as is the location, convenient to some of Oaxaca’s most iconic sights, including the Santo Domingo Church.

The real voyage of discovery consists not in seeking new landscapes, but in having new eyes. ~ Marcel Proust. For my inaugural highlight on AFAR, I am starting with my wife’s favorite quote, and a local sight in Chicago. Sometimes people feel they must jet off to some far off exotic place in order to ‘travel.’ However, if you gaze anew at your immediate surroundings with fresh eyes, you will discover an entire host of wonderful surprises. Here we have Cloud Gate, located down in Millennium Park, back before they buffed out the seams. The contrast between the organic form of ‘the bean’ and the structured grid lines, along with the warped fun house mirror quality of the city, makes this a truly unique destination.

Salzburg’s 17th century Baroque cathedral, built upon a site where cathedrals have stood since the 8th century, is connected with St. Peter’s church and the Residenz by arcades to form a cluster of Salzburg’s most important structures.

Inside is not entirely different from other major cathedrals, with beautiful artwork, ornate carvings and a selection of relics (Virgil, Rubert and Martin of Tours among others). Most notably, however, is that it contains the baptismal font used for Salzburg’s most famous resident, Wolfgang Amadeus Mozart. It rests on four lions which, being designed at a time when very few knew what an actual lion looked like, resemble something more like a beastly bulldog than king of the jungle.

In a country full of swanky resort towns, St. Moritz takes the crown with its wide array of five-star hotels, designer stores, and award-winning restaurants. The town is also home to such exciting activities as skijoring and ice cricket, which help to keep all the celebrity visitors entertained.

Nothing is a more powerful symbol of the City of Light than the Eiffel Tower. Designed by Gustave Eiffel for the 1889 Paris Exposition, it’s one of the world’s most-visited monuments, with nearly 7 million people ascending the 1,062-foot wrought-iron structure each year. Glass elevators spirit you to the top—hardy souls can take the stairs part of way—where in addition to unparalleled panoramic views of Paris, you can toast your arrival with a glass of bubbly at the Champagne bar. Evenings there’s a grand light show: every hour on the hour, the tower sparkles for five minutes with 20,000 bulbs.

Keswick Hall was originally built in 1912 as a family estate and was later a country club before being transformed into a country hotel in the 1990s, and it continues to evolve as a luxury resort in its second century. Experience a bit of the historic grandeur with an elegant al fresco dinner overlooking the countryside at Fossett’s restaurant or with a cocktail at the Villa Crawford bar (named for the original home), before retiring to your room on a bed fit for royalty. (Indeed, the handmade Hypnos mattresses are also commissioned for the British royal family.) Each of the 48 uniquely designed rooms and suites overlook the golf course or gardens, and have minibars stocked with local goodies. You’ll need a good night’s sleep to properly enjoy a full day’s activities on property: a round of golf on the Pete Dye–designed Full Cry course, a tennis match on one of seven courts, or a game of croquet or horseshoes (just a few of the games on offer). Wind down with a massage, signature vinotherapy facial, or raindrop therapy with essential oils at the spa. If you can bear to leave the lush grounds, downtown Charlottesville and the Monticello estate are each a 15-minute drive away.