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Home to Mexico’s largest concentration of artisans, Tonalá—just 10 minutes from Tlaquepaque—is known for its pottery, hand-blown glassware, textiles, miniatures, and more. On Thursdays and Sundays, the town hosts an open-air market, or tianguis, in its main plaza—and has since Prehispanic times—during which visitors can shop stalls from more than 400 craftspeople. If you can’t make it on market day, you’ll miss the hustle and bustle but can still visit the stores and family-run workshops where the artisans produce their unique wares.

The real voyage of discovery consists not in seeking new landscapes, but in having new eyes. ~ Marcel Proust. For my inaugural highlight on AFAR, I am starting with my wife’s favorite quote, and a local sight in Chicago. Sometimes people feel they must jet off to some far off exotic place in order to ‘travel.’ However, if you gaze anew at your immediate surroundings with fresh eyes, you will discover an entire host of wonderful surprises. Here we have Cloud Gate, located down in Millennium Park, back before they buffed out the seams. The contrast between the organic form of ‘the bean’ and the structured grid lines, along with the warped fun house mirror quality of the city, makes this a truly unique destination.

Color, shape, and naked geology: Northern Arizona appeals to the senses in the most elemental ways. Agnostic hikers, secular scientists, souls searching for spiritual energy — all end up in Sedona, seeking and finding. Mid-week in this red-rock country, we found a few days of calm: early morning trails around town, and afternoons in galleries seeking shelter from summer thunderstorms. Weekends bring crowds from Phoenix, just two hours to the south, but away from pavement, you can still get away into the elements.

Scattered with Victorian mansions, St. Paul’s tree-lined Summit Ave. is one of the most beautiful residential streets in the Midwest, with famous former residents including author F. Scott Fitzgerald and early railroad entrepreneur James J. Hill. Guided tours are offered from the James J. Hill House Wed–Sun, but it is also a worthwhile independent stroll. Make sure to start or end at the gorgeous St. Paul Cathedral, overlooking downtown St. Paul.

Though his reputation is now arguably overshadowed by that of his former wife, painter and muralist Diego Rivera—commissioned by Mexico’s postrevolutionary governments starting in the late 1920s to adorn several national monuments in complex, pageantry- and allegory-laden wall paintings—was among the first Mexican artists to gain worldwide acclaim. Many of his finest works are on display in the Centro Histórico. Perhaps most spectacular are Rivera’s portrayals of Mexico’s millennia-long history, as seen in the Palacio Nacional on the Zócalo (Mexico City’s main square; take a state-issued ID for admission to the palace); a more contemporary depiction of socialist workers’ struggles (and one which includes a Frida Kahlo cameo) decorates a courtyard at the Secretariat of Public Education. One of the artist’s earliest pieces can be seen inside the amphitheater at the San Ildefonso museum. Additionally, the dazzling Sueño de una Tarde Dominical en la Alameda Central, a surrealist who’s-who of Mexico’s turbulent fin de siècle, is the chief artwork on display at the nearby Museo Mural Diego Rivera.

One of the most famous sights in Germany, the Cologne Cathedral (known locally as the Kölner Dom) lives up to the hype. Its Gothic exterior, and especially its soaring twin spires, can be seen from all over the city, and its immense interior—measuring a whopping 66,370 square feet—brims with religious and cultural treasures. While its first stone was laid in 1248, the cathedral wasn’t finished until 1880. Today, its highlights include the Altar of the Patron Saints of Cologne by Stefan Lochner, the carved oak choir stalls, and the stained glass windows, which range from 13th-century examples to a more recent (and striking) addition by contemporary artist Gerhard Richter. The real treasure, however, is the Shrine of the Three Kings—an impressive work of medieval gold craftsmanship that’s bigger and grander than any other in Europe. Take it all in, then climb the 533 steps to the viewing platform on the south tower for a look over the city and, on a clear day, out to the Siebengebirge. Also be sure to visit the treasury, which holds artworks made from gold, silver, bronze, and ivory, as well as holy relics and sculptures from the Middle Ages.

Every Wednesday and Saturday, a farmers market sets up in Union Square in New York City. On the west side of the square, by 16th Street, is an orchard stand which makes the best apple cider donuts in the entire world. Breezy Hill Orchard is always there with many different types of apples, pears, pies, baked goods and - best of all - apple cider donuts. A bag of three will only cost you a few dollars. Coupled with a cup of hot apple cider, it might just be the most perfect breakfast. Pull up a seat on one of the many benches in the park and gaze up through the towering trees as donut crumbs tumble down your chin.

Perched on a steep hill in the lovely neighborhood of Alfama, you will in no doubt leave with a great souvenir or gift. Sellers throw down blankets or rugs in rows and sell a variety of hand-made goods, antiques, books, clothes, military objects, etc. I took home two wonderful brass bottle openers and a couple of old world maps. Getting to the market is easy and the trip there is quite beautiful; take the Tram 28, or Tram 12 up the hill through the tight, and narrow neighborhood streets (becos). After you’ve spent all of your Euro, take a short walk over to the Santa Engracia Church, Museum of Decorative Arts, or the National Pantheon. Oh, and don’t forget to take in the views and snap a few pictures.

Little-known fact: New Orleans was the first place in North America to license pharmacists (starting in 1769, when the city was still under Spanish rule). After Louisiana became a territory, the U.S. governor extended the requirement, also decreeing that pharmacists take a three-hour licensing exam in order to practice. And no wonder illness got such attention—the city was arguably the least healthy place to live on the continent; it was riddled with yellow fever, malaria, and dysentery. This dark but fascinating history is explored in this atmospheric 1822 town house, which was once the home and shop of Louis J. Dufilho, the first licensed pharmacist in the city—and hence in the country. Exhibits include apothecary jars, tools of the trade, and leeches. (Yes. Leeches.)

Mexico has three mountain ranges named Sierra Madre (Mother Mountains), and the range near Puerto Vallarta is covered with dense jungle vegetation and terrain that has been described by one outfitter as “chassis-challenging.” For active travelers who enjoy the outdoors, excursions into the mountains promise all sorts of possibilities, from hiking to rappelling and zip lining. Good health, a knowledgeable guide, a change of clothes and a sense of adventure are all required.

Visitors with a particular interest in the grunge scene should make a trip to West Seattle’s Easy Street Records — Eddie Vedder lives in the neighborhood and has been known to shop here. But aside from that, Easy Street is just a great local independent music store, with a wide selection of CDs and records, and knowledeable staff. The attached cafe is a diner covered in music memorabilia that serves up good, basic breakfast and lunch. And an Easy Street T-shirt, with its distinctive red star logo, makes a great gift for your favorite music lover.

Set smack bang on the beach at Canggu’s Batu Bolong surf spot, Old Man’s is where surfers rinse off the salt and head in for a beer and a bite to eat. The beer garden’s open and airy atmosphere is enhanced by strings of lights and awesome murals by Australian artist Lucas Grogan. You really can’t go wrong at Old Man’s: Prices are affordable, it’s family- and dog-friendly, and the sunset is spectacular. Drop by and see what the hype is about.

The establishment bears two names for a reason. Lenox is the front room, a restaurant chasing after that holy grail of U.S.-style diner food that’s just refined enough to appeal to the beautiful people (remember Max’s Kansas City?). Tables are tight and eavesdropping may be impossible to avoid, so watch what you say. Behind Lenox lies Parker, a larger (if just as crowded) space, home to live music, sexy lounge areas, and a long, shimmering bar whose staff is thoroughly up-to-date on the latest craft cocktails. What might first seem like a cliquey crowd opens up after a drink or two.

The bay of Les Saintes ranks among UNESCO’s list of most beautiful bays in the world—and it’s not hard to see why. The views, whether on approach from the sea or from atop one of its bluffs, make up a dreamy Caribbean postcard, with the bluest of waters punctuated by small sailboats and a few docks, and its shores lined by sugar-white beaches. Under its surface, coral reefs thrive, making it an excellent snorkeling and diving destination. Lazying on a catamaran drifting across the bay is also a worthwhile experience, whether you get into the water or not.

Take a leisurely day trip (or a couple of days) to drive around Inishowen, the largest of Donegal’s peninsulas and enjoy the rugged scenery, with remote beaches, stone forts, castle ruins and a military museum at Dunree Head to explore. The total drive is 157km (98 miles) and you’ll find plenty of villages, cafes and pubs to stop at for food and refreshments along the way.

You’ll have the most dramatic views on your way to Malin Head at the tip—be sure to stop at the Gap of Mamore, 820 feet above sea level, for panoramic vistas of Lough Swilly and the Fanad Peninsula. Along the way you’ll also see lots of long, golden beaches and coves, sheep-filled fields, traditional cottages, and villages to stop by for lunch or refreshments. Inishowen is also home to some of Ireland’s most fascinating Christian and Gaelic sites, such as Grianan of Aileach (Grianán Ailigh in Irish), a ring fort dating back to the 6th century C.E.