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A cultural hub for Turkish and international art, Istanbul Modern opened in 2004 as a permanent home for the contemporary Istanbul Biennial. The 8,000-square-foot warehouse sits along the Bosphorus next to the Golden Horn, a historically important port for thousands of years. The water views rival the exhibitions for your attention and appreciation, and the museum has an excellent restaurant and terrace to take advantage of the location. Back inside, the permanent collection shows contemporary and modern artists from Turkey, with rotating exhibitions of photography, design, and new media. The downstairs cinema has several screenings a week of films that complement exhibitions or feature distinctive work, often accompanied by panel discussions. The gift shop is one of the best places to buy unusual and beautiful souvenirs such as upcycled jewelry and kids’ coloring books of museum art.

One of South Africa’s most famous sights, Robben Island is located four miles to the west of Cape Town. Its history as a prison is almost as old as the first Dutch settlement on the cape, dating all the way back to the 17th century. Today, the island is a UNESCO World Heritage site and museum, offering guided tours by former prisoners. After visiting the graveyard and maximum-security facility, guests can finish with a stop at the cell of the island’s most famous prisoner, Nelson Mandela. The half-hour ferry ride to Robben Island includes breathtaking views of Cape Town and Table Mountain. Just note that the ferry only runs three times a day in the low season; in the spring and summer, there’s an additional departure in the late afternoon. Book your tickets far in advance.

Little-known fact: New Orleans was the first place in North America to license pharmacists (starting in 1769, when the city was still under Spanish rule). After Louisiana became a territory, the U.S. governor extended the requirement, also decreeing that pharmacists take a three-hour licensing exam in order to practice. And no wonder illness got such attention—the city was arguably the least healthy place to live on the continent; it was riddled with yellow fever, malaria, and dysentery. This dark but fascinating history is explored in this atmospheric 1822 town house, which was once the home and shop of Louis J. Dufilho, the first licensed pharmacist in the city—and hence in the country. Exhibits include apothecary jars, tools of the trade, and leeches. (Yes. Leeches.)

This beautiful one-mile stretch was donated to the people of the Virgin Islands by Arthur Fairchild, a benefactor of the islands who’d made his fortune on Wall Street before retiring here. The usually calm waters of the heart-shaped bay make the beach the most popular on St. Thomas. Rent beach chairs and floats, and pick up lunch from stands selling burgers, pizza, and other snacks. Lifeguards are on duty every day.

With more than 250 acres of grounds, the New York Botanical Garden manages to fit a number of different landscapes and experiences into its garden walls. The garden was established in 1891, the inspiration of Nathaniel Lord Britton and his wife, Elizabeth, who returned from a trip to England determined that New York should have its own equivalent to London‘s Kew Gardens. They found backing among New York society and created one of the country’s leading research institutions that also happens to be an ideal place to commune with nature right in the city. The rose garden designed by Beatrix Farrand is a highlight, while an abundance of azaleas reaches their peak in May. In all there are some 20 different gardens, including one dedicated to native plants, a rock garden, and a wetlands trail. The conservatory, constructed in 1902, is the largest in the country and includes 11 different climatic zones. When the last of the fall foliage has fallen from the trees, the conservatory hosts the popular annual Holiday Train Show (from the end of November to mid-January).

Simplicity reigns at The Charter Oak, the gamechanging restaurant owned by Christopher Kostow (who also helms the kitchen at The Restaurant at Meadowood). The family-style menu by chef Katianna Hong features “elemental” cooking, with dishes that highlight only one or two ingredients at a time. The best representation of this is the crudités, raw vegetables from the restaurant’s farm, served on a bed of crushed ice with a side of fermented soy dip. Another example? Crudo of kanpachi with grilled Rangpur lime and herbs. Most of the menu’s larger dishes are seasonal and prepared in a hearth at the center of the restaurant. Highlights include roasted pork shoulder with spiced molasses and winter squash, and beef rib grilled over cabernet barrels and beets dried over the fire. The most Instagram-worthy part of the meal may be the moment the server explains where to find the silverware—forks, knives, spoons, and napkins are stored in hidden drawers on the side of each table. During warm summer evenings, precede your meal with a few rounds of handcrafted cocktails in the open-air courtyard out front. The happy hour of half-priced beers and $3 shots of Fernet-Branca can’t be beat.

This upscale New American restaurant in a brownstone near Rittenhouse Square is a popular destination for business dinners and special occasions. Chef Greg Vernick is a James Beard Award winner, and the restaurant regularly appears on many national and local “Best of” lists. The dinner menu changes with the seasons, but favorite options include the sea urchin and the roasted whole fish of the day. For dessert, look for the tasty blueberry pie, which is served with elderflower ice cream. A highlight of the cocktail menu is the Milk Punch—a classic rum drink made with Madeira, lime, and bitters.

Dating back to 803 C.E., the St. Peter Stiftskulinarium is said to be the oldest restaurant in Europe. While there’s a fine contemporary Austrian menu, the history and atmosphere of the various salons and dining rooms are an even bigger draw. The arcaded courtyard in particular is charming and turns into a winter wonderland during the Christmas-market season. The highlight for most travelers will be the Mozart Dinner. Taking place in the stunning ambience of the Baroque Hall, the meal is served with a performance by an ensemble of Mozarteum University Salzburg graduates wearing period costumes—wonderful musicians who also work with renowned orchestras.

Could there be a more glorious setting for a cheese’s origin? These pastures surrounding a hilltop village (Gruyères) crowned with a castle (the Château de Gruyères), happy Swiss cows grazing with views of the Alps all around, producing the milk which, in time, arrives on grocery shelves as cheese around the world, stamped ‘GRUYÈRE’...and there’s a geometric garden in the castle’s courtyard, too.

Spoken of in almost reverential terms by people that have traveled there, Sa Pa is often seen as a holy grail of destinations in Vietnam. Part of that is because of the environment—a cool mountain town that has lured visitors with its salubrious air and alpine scenery since the early 20th century, when the French constructed facilities for sick officers to recover—as well as its remoteness, located close to the Chinese border in the country’s extreme north. Most visitors come to Sa Pa for the hiking in the nearby valley peppered with minority-ethnic-group villages, or to climb Mount Fansipan, the country’s tallest peak, which is located just southwest of the town. Conquering the summit once required a two-to-three-day hike, but now can more easily be reached with the help of a cable car (opened in 2016) that gets you most of the way.

Downtown Bryson City is home to the welcoming Everett Hotel and its restaurant, the Bistro. Although famous for its crepes, the Bistro’s mountain trout preparations rival the finest riverside camp cooking, including, notably, the trout cakes, a highlight of the Southern cuisine–driven tapas menu. Ingredients are sourced locally and seasonally, and many are organic. Although the rustic, candelabra-lit atmosphere is relaxed, reservations are recommended, especially during summer and on weekends. Guests at the Everett enjoy complimentary breakfast and weekend brunch, and many eat here multiple times during a visit to the Smokies.

For a seafood experience featuring fresh-caught Adriatic fish, book a table at this lovely restaurant in the small harbor of Foša Zadar, right by Zadar’s ancient city walls. The interior incorporates original details, like exposed bits of stone walls, in an overall contemporary design, but the real standout is the terrace that extends into the port. It’s the perfect setting if you want to pair your meal with stellar vistas. Though the meat dishes here are great, seafood is the highlight. The menu changes according to the morning’s catch, but often features shrimp gazpacho, gnocchi with black cuttlefish ragout, and grilled Adriatic Sea bream with fresh herbs.

One of Japan‘s most talented chefs, Yoshihiro Narisawa presents Japanese ingredients in a style he calls “innovative Satoyama cuisine,” which highlights the country’s natural bounty. Narisawa works directly with purveyors to get the freshest seafood and produce. Bread is cooked on the table, there is soup made from soil (yes, literally dirt, along with burdock roots), and a forest-inspired dish that has a live audio feed from a forest in Japan. The exquisite meal is not gimmicky and involves a dizzying array of ingredients, and the wine-pairing option includes some very interesting, untraditional sakes, a great education in the spirit. Knowledgeable staff explain the provenance of each dish—it’s like an edible tour through Japan.

Families would be hard-pressed to find a more memorable place to stay than Giraffe Manor. Located in the leafy suburb of Langata, about a 30-minute drive from central Nairobi, the 1932 family home of a former candy baron was modeled on a Scottish hunting lodge before becoming a sanctuary for endangered Rothschild’s giraffes, for which the boutique hotel gets its name. The ivy-clad brick mansion features 12 light-filled guest rooms, many with gauzy canopy beds and understated furnishings, but the real draw is the airy breakfast room, where you can feed the exceedingly friendly animals as they crane their necks through windows and doors in search of snacks. Afterward, complimentary chauffeured vehicles are on hand to take you to the area’s most popular attractions: at the David Sheldrick Wildlife Trust, the residents being fed are orphaned baby elephants.

This pink-marble waterfront edifice in Piazza San Marco dates back to the 14th century, when it was the residence and seat of government for the doges (rulers) of Venice. Today the ornate Byzantine- and Moorish-influenced Gothic Palazzo Ducale is a symbol of the city, and serves as a museum hosting some of Venice’s most important art, including the famous Bacchus, Venus, and Ariadne masterpiece by Tintoretto. It also runs the popular Secret Itinerary and Doge’s Palace Hidden Treasures tours. After you’re done, treat yourself to a glass of wine in the small on-site bistro, with windows looking onto the Grand Canal adjacent to the Bridge of Sighs.