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Get on the road again to experience these tuneful itineraries through the Mississippi Delta, along the California coast, and more.

Where will 2022 take you? Below, you’ll find 39 destinations—from Abu Dhabi to Alberta, Canada—where your visit will really count. Locals tell us what’s new, exciting, and worth the trip in the coming year.

The Mighty Mississippi is one of the longest and most storied waterways in America. Cruises on the river offer a unique vantage point from which to experience the history and culture of the country’s heartland.

Four Charleston tastemakers explain how the city inspires their art and fosters a sense of community. Plus: an insider’s guide to exploring the city.

Major metropolises are often known for their innovation and creativity, but these smaller towns and cities punch above their weight.

Meander the cobbled streets, climb an historic volcano, and be sure to try a wee dram of whisky.

Hitting the road with three generations (or more) is a lot, as this writer knows, but there are plenty of ways to make it a great travel experience for all involved, whether they are 8 months old or 80 years old.

From an Eero Saarinen–designed terminal at New York’s JFK to a frozen bay in Ilulissat, Greenland, these airport hotels are worth building a trip around.

Surf in Rincón, kayak a bioluminescent bay, enjoy beaches in Vieques and Culebra, and more.

In the aftermath of catastrophic rains and flooding, a writer based in Kenya offers the latest updates on how local citizens, safari lodges, camps, and wildlife are faring, along with a vetted list of aid organizations.

Cruise icy fjords and track pumas in Chile’s Magallanes region.

What could be more all-American than escaping your everyday routine and holing up in a cozy retreat by one of the country’s picturesque lakes?

From Shakespeare in the Park to SummerStage, New York’s iconic summer and fall happenings are back on this year.

Avoid the crowds of seven popular national parks and visit these state parks instead.

From more eco-friendly sailings to immersive journeys that will get you deeper into the culture and nature of the region, these cruise itineraries will bring you along Norway’s beautiful coastline in comfort.