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Designed by 19 of the world’s top architecture and design firms (three of which have already won the Pritzker Prize), the Hotel Silken Puerta América Madrid may be the world’s ultimate design hotel. A colorful, towering ode to the best of modern design, the hotel is unlike anywhere else, with each distinctive floor imagined by a different creative, including the likes of Zaha Hadid (her vision is an undulating space-age den of all-black or all-white rooms and smooth fiberglass surfaces) and Jean Nouvel (his gradient exterior is just the tip of a vibrant, imaginative iceberg). John Pawson imagined the Zen-like, all-wood lobby, while architect Teresa Sapey created what may be the world’s only whimsical, design-conscious parking garage, a brightly colored and well-lit space inspired by Paul Éluard’s poem Freedom, which adorns the building’s facade.

Despite each floor’s unique and avant-garde aesthetic, the Hoteles Silken group refused to compromise on luxury, guaranteeing top-notch service and every modern amenity one would expect from a five-star hotel. And don’t forget the acclaimed restaurant, two trendy bars (one on the rooftop, with postcard-worthy views), and the indoor rooftop pool.

Playful shoe designer John Fluevog’s flagship store is right in Gastown on Water Street in a gorgeous two-storey glass-fronted building that houses the design team upstairs and you’ll find his eccentrically elegant designs on the ground floor. I love his designs, and there’s always a cute message on the soles so make sure you flip them over to look when you visit.

Quinta de La Rosa was built in an unusual location, on a hill with steep stairs that connect the different levels besides the Douro River. The Bergqvist family has been making Port wine since 1815. The Quinta de La Rosa estate was offered as baptism gift to Claire Feuheerd, Sophia’s grandmother, in 1906. Guests can stay in traditional family House or in the new and more modern building.

Located in a historic Art Deco building inside Volunteer Park, the Asian Art Museum contains a permanent collection of jades and ceramics, sculpture, textiles, and Chinese painting and calligraphy, as well as temporary exhibitions featuring everything from illuminated Persian manuscripts to modern Japanese anime. The Gardner Center offers public programs such as talks, author events, and artistic performances to introduce visitors to new cultural perspectives.

Though it has somewhat limited hours, the Palm House in the heart of Copenhagen‘s botanical gardens is open year round and a lovely spot to visit. Built in the late 1870s, the structure is everything you would expect from a building dating back to that era including cast-iron spiral stairs, and butterfly room.

Architecture fiends should make a lunch date at Café Grosch. Located on historic site Bankplassen, the building dates from 1828 and was originally used as – you guessed it – a bank. The café’s namesake was architect Christian Grosch, and even the tables and chairs in the café are designed by architects and designers. The arched ceilings and antique red brick floor gives this place a distinctive Scandinavian feel, and the menu complements the ambience nicely.

Through the end of June, the Museo di Sant’Agostino hosts a fascinating exhibit on the Machines of Leonardo DaVinci - including his bicycle, the air screw, and a massive interpretation of one of his earliest gliders. Housing in a converted monastery, the building itself is also a lovely space to visit the 16th and 17th century paintings and sculptures on permanent display.

While Enrico himself did not open his shop until 1998, he works in a building, and continues a tradition, that dates back centuries. You can purchase one of his hand-tailored shirts ‘off the rack’, or splurge a bit and have him make one exactly to your specifications (with his signature double-button collar). Or grab a specialty tie with a striking nautical flag embroidered embelishment.

A shutterbug’s dream come true: two buildings of several floors each house any camera, lens, or piece of photography equipment you could ever want. From brand-new DSLRs to vintage Hasselblads and everything in between, this behemoth market is likely to have whatever you may be looking for, or hold surprises you didn’t even know existed. Tip: keep an eye out for a few original Seagulls manufactured in Shanghai.

A unique feature of Getaria’s city streets are the grills, built into the side of buildings. The outside observer can glean that the general purpose is cooking, but seeing them in action is a different story. Fish are brought fresh from the port, laid on the smoking grills, and adorned solely with olive oil and salt. Fresher doesn’t exist. Dine at one of the restaurants lining main street to experience this for yourself.

Victoria Eugenia is a double-edged sword. A beautiful, red-velvet-swathed theater occupies the aboveground section of this building. Offerings feature biggish names in music, Broadway adaptations, and classical performances. Meanwhile, after midnight, it’s the basement that houses the action. The underground level is a dance club that’s at its peak from 2am on. Expect house music and house remixes of Top 40, as well as a lively, twenty- and thirty-something crowd.

Montes + Mugica is a furniture studio and clothing store that devotes itself to good, clean taste. It’s been in the family for generations, but each generation has brought a new style to the shop. The young brothers José and Javier bring a distinct affinity for all things Nordic, resulting in a gorgeous, hip aesthetic and real treasures for sale. Don’t miss their monthly pop up market in their other building, Espacio La Central.

During the late 19th and most of the 20th centuries, the Testaccio district hummed with activity from the sprawling slaughterhouse. Thought animal slaughter was moved away from Testaccio in 1975, most of the building has been preserved. In recent decades, areas have been slowly transformed for new functions. The place houses a contemporary art exhibition space called the MACRO, a university campus, and even an organic supermarket (open Tuesday to Sunday).

Smoothies go great with warm weather. This cozy little place is tucked in the back of the building—look for the cow by the front door on the little lane called Mills Place just before McCormick Alley. Juice Farm’s organic, cold-pressed beverages use the freshest and best raw ingredients, from fruits and veggies to cacao and bee pollen. They have a creative selection of smoothies, cold-pressed juices, wellness shots, and juice cleanses.

Of course I was in awe of the imposing temples at Tikal, but my favorite area was the Central Acropolis. Walking through the various buildings of this residential complex, it was easy to imagine how it might have been when people lived here. I lingered for a long time, wandering through all the halls and chambers, and finally climbing the stairs to take in the view from above. A magical place...