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Pamela Echeverría founded her original Avenida Ámsterdam space in 2010, after experiences at Galería OMR and the Museo de Arte Carrillo Gil. Since then, the gallery has made a name for itself by providing a forum for contemporary-art proposals based on impassioned research; its catalog has included artists such as Teresa Margolles (2009 Venice Bienniale and the 2012 Prince Claus Award), Erick Beltrán, Santiago Sierra (2003 Venice Bienniale, representing Spain), and Héctor Zamora, as well as Jill Magid, Pablo Vargas Lugo, Terence Gower, and Antonio Vega Macotela. Labor’s current headquarters were originally functionalist architect Enrique del Moral’s 1948 residence and lie just across the street from 1980 Pritzker Prize winner Luis Barragán’s house, which was declared a UNESCO World Heritage site in 2004.

Hop on a lightweight bicycle and learn about the history of the Philippines on a guided bike tour around Manila’s old walled city of Intramuros. The bikes are handmade in the Philippines from bamboo, a natural vibration dampener, and fibers from the abaca plant (similar to a banana); Bambike Revolution Cycles won a Manila FAME Katha Award for Eco-Design in 2015. This is a unique alternative to a walking or bus tour, and takes you inside a walled city that is not normally accessible to bigger groups. Intramuros almost doesn’t feel like Manila: The Spanish influence is evident in the architecture, which includes some of the oldest baroque churches in the Philippines. Fort Santiago still houses underground dungeons as well as a tiny underground chapel, hidden at the end of a tunnel. At the Rizal Shrine you will learn about the life of José Rizal, the country’s national hero who played an instrumental role in the Philippine rebellion against Spanish colonial rule, and follow in the footsteps he made as he took his last walk in the fort from his cell to his execution.

Lucerne is no stranger to mass tourism: The otherwise lovely medieval city swells each summer with list-checking visitors en route to central Switzerland’s famed Pilatus and Titlis mountains. Surprisingly, few of them make the 15-minute trek from the train station to this gorgeous 19th-century badi (open-air swimming area) on the Lucerne National Quay, overlooking the clear blue waters of what the locals call the Vierwaldstätter See (aka Lake Lucerne). The entire facility was meticulously restored in 2010 and remains a favorite of residents for its excellent views of brooding, multi-horned Mount Pilatus, Jean Nouvel’s lakeside KKL performance hall, and Santiago Calatrava’s Lucerne Station Hall—and all without the hassle of tourists.

Atop St. Paul’s Hill sit the ruins of St. Paul’s Church, built by the Portuguese and consecrated in 1521. Malaysia’s oldest church was first Roman Catholic, then Dutch Reformed and ultimately used by the British to store gunpowder. Missionary St. Francis Xavier was briefly interred here (after three weeks his remains were sent to Goa, in India, where they can be found to this day); an open grave marks the spot where he was buried. Adjacent to the church is the Porta de Santiago, all that’s left of the Portuguese fortress A Famosa; built in the early 16th century after the Portuguese took control of Malacca, the fortress was used by both the Dutch and the British.

English explorer and draftsman Frederick Catherwood and American adventurer John Lloyd Stephens were the first foreigners to rediscover Copán and numerous other Maya cities. Catherwood’s extraordinary lithographs, on view at the Catherwood House Museum, portray those monuments as they appeared when the pair first witnessed them; the institution’s Belle Époque setting transports visitors to Catherwood’s day and conjures the wonder he experienced as he wandered the Maya world of Mexico and Central America. A coffee enjoyed in the courtyard and a poke through the elegant gift shop are icing on the cake.

Making its debut one the list of the 50 best restaurants in Latin America in 2015, young chef Carolina Bazan, takes the abundance of Chilean markets and sensational produce and delivers them with a creative, slightly French flare to diners. Originally located in downtown Santiago, the restaurant has relocated out to Las Condes to more spacious digs surrounded by their gorgeous garden. Standout dishes on the menu are Wagyu pot roast with creamy blue cheese mashed potatoes and they make a delicious homemade ketchup and Bearnaise sauce. Service can slow so go with patience--and a reservation. Pamplona 78, Las Condes +56 2 217 3075 Photo: Carolina Bazan (Ambrosia)

The Villa Grimaldi Memorial and Park for Peace occupies the site of a former interrogation and extermination center operated under Chile’s 1970s and ’80s-era military dictatorship. A wall lists the names of the prisoners who died here, and there’s a garden with a rosebush for each woman executed or “disappeared” that was inspired by survivors’ stories of being able to smell the roses outside their cells. Willows convey sadness engendered by the unspeakable crimes committed on the property. (Only the foundations of the original estate remain, but a model can be viewed.) A focal point of the garden is a gigantic tree that was burned down but somehow survived and grew back to its present-day height of more than 50 feet, a symbol of the indomitable human spirit.

The internationally inspired fare (Asian and Italian, mostly) at Oasis Ocean Club is good, but most guests patronize this spot for its enviable views and its lively atmosphere. Sitting right on the waterfront, the two-level restaurant looks out onto the bay and truly is one step from the beach. Live music and an exceptionally friendly staff draw repeat visitors.

As wine booms in Chile, Barrica 94 is the newest addition to the city’s wine bars. Located in the tourist-friendly Patio Bellavista in Bohemiam Bellavista, Barrica 94 is all about La Vid. Interior murals were designed by local painter and designer Tomás Ives and are contrasted by plush leather benches, and a wine list that will make grape lovers sing with delight. What to do here? Taste, taste, taste. The knowledgeable staff can help you and while wine is the star of the show, you can order some nibbles to complement them.

Las Cumbres is the newest of the bunch of hotels to open in 2015 in Lastarria. Cuddling the backside of Plaza Mulato Gil, the hotel fused itself to the existing colonial structure with an edgy, modern architecture. Inside the rooms have clean lines and an understated design overseen by king designer, Enrique Concha. Sporting 73 rooms, conference areas, an outdoor pool, and tapas bar, it’s just brought more buzz to an already happening area of town.

One of Mexico City’s most historic neighborhoods—a once-independent city-state politically joined to the Aztec capital of Tenochtitlan—Tlatelolco is a fascinating side trip few tourists make. At its center lies the district’s so-called Square of the Three Cultures, where a colossal public housing development (of revitalized interest to architecture buffs) surrounds a 17th-century Spanish church (notably embellished with stained-glass windows by 20th-century artist and architect Mathias Goeritz) as well as the ruins of pre-Hispanic Tlatelolco pyramids and other structures. In addition to being the exact spot on which the Aztec empire fell, the square was also the site where Mexican armed forces perpetrated a bloody 1968 massacre of university students and political activists. Tragedy aside, the area is still home to thousands of hardworking average Joes, and the community garden, known as the huerto, is pure down-home bucolic charm; it’s well worth a pop-in.

On this episode of Where to Go, Aislyn Greene talks to Mark Johanson about Arequipa—the White City’s luminous sillar architecture, its fiery picantería food culture, and the deep canyons and new safari‑style camps reshaping southern Peru travel.

In this week’s episode of Unpacked by AFAR, we talk with actor and writer Andrew McCarthy, author of the new book Walking With Sam, about his 500-mile Camino de Santiago pilgrimage with his teen son in tow.