If you are a fan of trinkets and ephemera, you'll have a blast at the Charleston Museum—America's very first museum, founded in 1773. Focused on South Carolina Lowcountry, the location is a part of the Museum Mile, a section of Meeting Street with six museums, five historic homes, four parks, and other important churches and public buildings. It is filled with memorabilia and antiques, many dating back as far as the Civil War. From the vintage signs to the leech jar used in the 1830s by a Charleston doctor on the King of Siam, to the collection of toys, there is truly something for everyone. My favorite was the re-created apothecary.