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Elevate the normally mundane experience of shopping for medicine-cabinet basics like soap and toothpaste with a visit to one of the oldest pharmacies in the world. In this 13th-century chapel with early Renaissance frescoes, Gothic carved wooden cabinets, and crystal chandeliers, most items are still crafted according to formulas originally created by Dominican monks. A small museum displays equipment once used to make Santa Maria Novella products, as well as a collection of beautifully painted ceramic jars that held the herbs and powders. Linger a little longer in this fragrant world by ordering a pot of herbal tea or a small glass of one of the historic liqueurs in the tearoom.

If you had to choose one place to symbolize Rio’s Belle Époque, it would be this sumptuous café, a must-do for every downtown visitor. Built by a Portuguese family in 1894—when Rio still evinced the splendor of a former imperial capital—its art nouveau–inspired refinements like huge mirrors, imported from Europe, wood furnishings, immense chandeliers, and stained-glass transoms welcome patrons. Colombo is all so terribly majestic you could be at one of the Continent’s grand salons or even the Tortoni in Buenos Aires. Perfect for afternoons over a pastelzinho de Belém, Lisbon’s traditional sweet egg tart.

The Villa Grimaldi Memorial and Park for Peace occupies the site of a former interrogation and extermination center operated under Chile’s 1970s and ’80s-era military dictatorship. A wall lists the names of the prisoners who died here, and there’s a garden with a rosebush for each woman executed or “disappeared” that was inspired by survivors’ stories of being able to smell the roses outside their cells. Willows convey sadness engendered by the unspeakable crimes committed on the property. (Only the foundations of the original estate remain, but a model can be viewed.) A focal point of the garden is a gigantic tree that was burned down but somehow survived and grew back to its present-day height of more than 50 feet, a symbol of the indomitable human spirit.

For decades, Québec was viewed by many Canadians, and even many Québecois, as a conservative, traditional, and rural part of the country that was falling behind other provinces that were looking optimistically toward the future. Those are the years that would come to be known as the Grande Noirceur, or the Great Darkness. In 1959, Maurice Duplessis, known for his staunch Catholicism as well as fierce anti-Communist and anti-union policies, died, and he was followed by Liberal governments that led the so-called Quiet Revolution. Québec would emerge from this period as a decidedly cosmopolitan and socially liberal province. The Expo 1967 and the 1976 Olympic Games in Montréal proved to be key moments in which newly transformed Québec introduced itself to the world, and the buildings from both had huge impacts on the cityscape. The Olympic Park’s stadium, designed by French architect Roger Taillibert, is still used for sporting events as well as concerts. The inclined tower on the site has an observatory with sweeping city views. You can explore on your own, though there are also guided tours that provide an introduction to the architectural and engineering innovations of the Olympic Park’s buildings.

This beautiful Parisian cemetery is on the Boulevard de Menilmontant and next to the Metro station Philippe August, in the 20th arrondissement. Upon entrance to the main gate, grab a map so not to get too lost. The art work on the memorials and the stories behind the names on the headstones inspire a mood of great tragedy and romance. The locals call it the la cite des morts (the city of the dead). The cemetery makes the ideal place to explore if you’ve seen a lot of Paris before and want to dig a bit deeper. Seek out the tombs of 1) Oscar Wilde (for all of those declarations and kisses left behind); 2) Georges Rodenbach, a Belgian writer and poet of the 19th century with a breathtaking tomb; 3) Victor Noir, who became more famous in death (by duel) than life. Seek the answer to the riddle of why his tomb is seen as good luck for fertility You’ll also see the gravesite of Gertrude Stein and Alice Toklas, buried side by side in a testament to their love. The list of the celebrity dead goes on and includes Gericault, Piaf, Chopin, Heloise and Abelard. Even Jim Morrison. An afternoon here is guaranteed to leave you grateful for the treasures you found but weren’t expecting.

Enter the former health foods store and you have moved back to the early ‘80s. This is a place where punk never died. Have a vegan sandwich and a beer with the Crippa label, and maybe—if you’re lucky—there will be an acoustic concert on the small stage. Acoustic punk, you say? Well, yes. And other music styles, if Crippa likes the band.

Just south of the historic center of Québec City, the Battlefields Park is one of the most important historic sites in Canada. Here, the dream of New France—a more than 200-year-long project by the French to colonize North America—was dealt a fatal blow. In 1759, during the Seven Years’ War, British forces under General Wolfe defeated the French troops led by General Montcalm. The battle on the Plains of Abraham lasted roughly 30 minutes. (The very biblical sounding name, by the way, comes from the fact that the land where the two armies clashed was owned by a farmer, Abraham Martin.) After defeating Montcalm (who died in the battle), the British took control of Québec City. By 1760, all of France’s territory in North America had fallen to the British, and in 1763, the French officially ceded their claims. History buffs make a beeline to this national historic site, but Québec residents mostly consider it a lovely urban oasis of 255 acres alongside the St. Lawrence River. In the summer, it’s the setting of outdoor concerts; in the winter, there’s an ice-skating rink (free of charge, and skates are available for rent) from mid-December to mid-March.

This might be the most photographed store in Florence—the charming but cluttered scene includes strings of dried garlic and chilies, baskets of fresh fruit, colorful ceramics, wooden serving utensils, wild-boar salami, Tuscan olive oil, and handmade copper pots—with displays inside the shop and spilling out onto the sidewalk. This historic establishment, on the ground floor of the old tower of Borgo Santi Apostoli, is so friendly that the owner will pour you wine and offer a few bites of pecorino cheese while you decide how much room is left in your suitcase.

The Milan Cathedral, or Duomo, occupies a site that’s been holy since the time of the Romans, but it wasn’t until the early 19th century when the finishing touches were finally placed on this massive building. The Duomo is the fifth largest cathedral in the world and one of the top tourist sites in the northern Italian city. Entrance is free, but a small fee is requested if you wish to take photos. Inside the church is even more magnificent then the outside, with scores of shrines and altars dedicated to saints and notable Milanese. During the Christmas holidays the city’s night market takes up residence next to the cathedral, adding one more reason to visit this central site.

Creamy gelato goodness is scooped from covered silver containers in this shop on the Piazza Passera. Scan the hand-lettered labels to see what is on offer—the kitchen behind the shop makes everything with the freshest seasonal ingredients. Try Fior di Latte alla Menta, the Italian version of mint chip ice cream, or any of the sorbets, which have a bright, pure fruit flavor. Carry your cone to a bench on the piazza and savor it as you people-watch.

When Mozart was a child, he performed here for Empress Maria Theresa; Franz Joseph I was born and died here, and his unhappy wife, Sisi, presumably sulked inside. Schönbrunn Palace, in the western Hietzing district, naturally invites comparisons to Versailles, as the Hapsburgs built it to rival the French palace. Today, the 1,441-room baroque masterpiece designed by Fischer von Erlach is a World Heritage site, with its Great Gallery and carriage museum among the draws. Its gardens are so vast that a small train takes you around to the palm house, an orangery, and a zoo. The recently renovated, columned Gloriette structure and its café look over the palace and, beyond, Vienna. Schönbrunn’s grandeur never ceases to impress—not bad considering that the palace was only a summer retreat for the Hapsburg rulers.

The most famous castle in Germany—and one of the best known in Europe—Neuschwanstein is renowned not just for its fairy-tale architecture (which directly inspired the Disney Castle) but also for its creator, “mad” King Ludwig II. Begun in 1868, it wasn’t completed until four years after Ludwig’s death, in 1892, but was very advanced for its time, with larger-than-usual windows, central heating, an elevator, telephones, and indoor plumbing. However, it’s the castle’s mountaintop setting and soaring towers that really impress. When visiting, be sure to check out the paintings inspired by the operas of Richard Wagner—Ludwig’s friend and the person to whom he dedicated the castle. Also take in the stellar views from the Marienbrücke, and if you want to visit in style, consider a horse-drawn carriage ride back to your car. There’s a restaurant on-site, but plenty of cheaper options are in the town below.

Stirling Castle is one of Scotland’s most impressive castles, particularly for its role in Scottish history—several kings and queens were crowned here, including Mary Queen of Scots. Tour the Great Hall, the lavish Royal Palace, the elegant Chapel Royal, and the Great Kitchens, then check out Argyll’s Lodging (Scotland’s finest 17th-century town house, built just beyond the castle walls for a great nobleman serving the royal court). Also worth exploring are the peaceful Queen Anne Gardens and the Stirling Heads Gallery, which features 16th-century oak medallions carved with images of royalty, Roman emperors, and characters from the Bible. When you’re done roaming the interiors, head outdoors and walk the ramparts to appreciate the castle’s commanding position above the Royal Burgh of Stirling.

Adjacent to the restaurant is a cheery boutique filled with gourmet products from all over Tuscany. Thanks to the restaurant’s long-standing relationships with many of the region’s top purveyors, you’ll find high-quality olive oil (tastings can also be arranged), cheeses, cured meat, preserves, breads, and more. Not all of it will make it through customs, but you can savor any perishables on a picnic to the Tuscan countryside.

This former royal palace is one of the largest museums in the world, and its art collection is considered one of the most comprehensive. It contains around 400,000 works, although—mercifully, perhaps—not all are on display at any one time. There are some pieces that never get taken off the walls. The Mona Lisa and her smile attract millions of visitors each year. Other must-see masterpieces include the sculptures Winged Victory of Samothrace and Michelangelo’s Rebellious Slave, and the Eugène Delacroix painting The Death of Sardanapalus. There’s no real trick to avoiding crowds at the always-packed museum. The best you can do is try to go in the off-season, early or late in the day, and on a weekday. Your chances of being alone with the Mona Lisa will still be slim to none, but you might be able to actually see that enigmatic smile behind the Plexiglas.