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Sample Turks and Caicos’s only locally brewed beer right from the source on a tour of Turk’s Head Brewery. It’s located in the Discovery Bay area of Providenciales, known locally as Provo, about six miles west of Grace Bay. Tours include a walk through the brewing facility, lessons on how the beer is made, and free samples of the finished product. You can also stop by the brewery to pick up cases of beer for significantly less than you’d pay at one of Provo’s grocery stores.

For the location of their first independent hotel, Atelier Ace (the creative arm behind the buzzy Ace Hotel Group) chose Panama City’s historic Casco Viejo, a once gang-ridden neighborhood now teeming with trendy restaurants, cafes, and wine bars in 16th- and 17th-century buildings. The American Trade Hotel occupies a stately property on Plaza Tómas Herrera, complete with 50 minimal-chic rooms and suites outfitted in Frette linens and custom, reclaimed-wood furnishings. Plush “Jardin” suites open onto a private garden courtyard, while others feature vaulted ceilings or views of the Gulf of Panama. On-site dining and drinking options abound, ranging from Café Unido for pour-over coffee made from Panama Geisha beans, to a jazz club created by Grammy-winning Panamanian jazz pianist and composer Danilo Perez.

An Old World grande dame of the 19th-century tradition, the InterContinental Amstel Amsterdam presides over the Amstel River from its waterfront perch at the eastern edge of the original city. An imposing example of a Dutch take on French Renaissance Revival architecture of the period, the hotel—known initially as the Amstel Hotel—was conceived of by well-to-do Amsterdam doctor Samuel Sarphati to attract wealthy Grand Tour–goers to the struggling city. Since then, dignitaries from Queen Elizabeth II to former President Bill Clinton, and celebrities from Audrey Hepburn to George Clooney, have entered the imposing lobby—with its grand staircase, marble columns, and gilded chandeliers—and taken up residence in its opulent suites.

While in its latest iteration the hotel has updated itself in all the right ways, it still offers each guest the superlative but understated service that such royals (of both state and silver screen) would expect, down to the private butler service that comes with each room. The current French-inspired decor channels the building’s original architecture and includes romantic hand-drawn wallpaper in bedrooms. The unfussy, seasonal cuisine and craft cocktails in the restaurants and bars infuse the traditional space with modern sensibilities. Even the health club has its feet in both past and present: The thoroughly modern facilities were inspired by one of the forefathers of physiotherapy, who took up residence in the hotel and treated such distinguished clients as Empress Elisabeth of Austria there.

The tony suburb of Houghton, whose best-known resident was Nelson Mandela, is home to leafy lanes lined with stately estates. Not too far from the Mandela family manse is the Residence, a stylish boutique property that lives up to its name, evoking a private lair of a chic distant relative that guests are fortunate enough to visit for a spell.

The rooms are plush, with velvet headboards, sumptuous rugs, and glittering chandeliers, but the bathrooms are a sight to behold: the gleaming marble tiles and outdoor showers and tubs merit a special mention. Nods to the nautical can be found in the Boat Lounge, where mini sailboats and life preservers inspire the decor. There’s often a pianist tickling the ivories in the Piano Lounge, where guests can retire with a post-prandial cocktail.

Just a short hour drive away from Kelowna, and only a 5-10 minute drive from Penticton, Naramata sits hidden with acres of green vineyards cascading off of clay cliffs into Lake Okanagan. In the heart Naramara is the historic Naramata Heritage Inn & Spa. Built in 1908, some say it’s haunted with its history of being a school and the first cultural hub upon Lake Okanagan. Today it functions as an ideal getaway with nearby beaches, over 100 wineries and the variety of adventure activities nearby. I always make time to stop in during my wine tasting trips to sit in the sun with a glass of local wine and a variety of local cheese and charcuterie selections. This is foodie stop one shouldn’t miss while visiting the area if not staying with the hotel. Take a tour through the chefs garden, tour the quirky town of artists and vintners, or enjoy the cycling, zip lines, hikes, fishing and water sports all within the Central and Southern Okanagan.

At the mouth of the Amazon, Marajó is the world’s largest fluvial (that is, river) island. With an area of 40,100 square kilometers (15,500 square miles), it is just a little smaller than Switzerland yet with a population of only some 250,000 residents. During the rainy season, much of this flat island becomes a vast lake. It is a popular destination for surfers, given the large waves created by the island’s tidal bore, and bird-watchers, who come in search of colorful species from scarlet ibises to blue herons.

Given its prime La Jolla location—with a Pacific panorama to match—this stylish, modern bar could get away with serving almost anything. But lucky for spirits enthusiasts, George’s Level2 (one of three venues that make up George’s at the Cove) literally wrote the book on San Diego’s craft cocktail scene: Stephen Kurpinsky, head barman and director of spirits and beer, collaborated with his staff to produce Neighborhoods of San Diego, a beautifully bound compendium of drinks, each representative of—and photographed in—a distinct corner of the city. As you flip through the book, which doubles as the bar’s menu, you’ll get the local lowdown—learning, for example, that around 25,000 pedestrians enter the United States via the San Ysidro border crossing daily. But mostly, you’ll learn that choosing a drink here is nearly impossible. The most popular option is the La Jolla: tequila infused with mango, lime zest, and chili blended with fresh lime juice, agave syrup, and a saline-and-suspended-seaweed ice cube. If you’re looking for something with fizz, the Little Italy—with prosecco and balsamic strawberry shrub, among other treats—is the way to go.

For many scuba divers, one of the most iconic spots in the Bahamas is the underwater area where a cargo ship and a prop airplane were used in underwater scuba scenes for Sean Connery–era James Bond movies. Located off the coast of New Providence, the dive site is simply called the Bond Wrecks because both can be explored in a single dive. The first is a mock-up of an airplane that was used as the Vulcan bomber in the movie Thunderball, while the other is a 90-foot Tears of Allah tugboat used in Never Say Never Again, which sits upright and intact in about 40 feet of crystal-clear water.

The Great Wall of China runs more than 21,000 kilometers (over 13,000 miles), not as one continuous wall but rather as fortified wall sections. Some of the sections date back more than 2,500 years, though only 8.2 percent of the existing wall is original. The Mutianyu Great Wall is one of the more accessible portions. Hike (because that is what you’ll be doing, even on the wall itself) up the Great Wall, then slide down the side of the mountain on a toboggan. Alternatively, explore the Simatai Great Wall, which retains a more authentic feel—save, of course, for the fake water town at the bottom. Even more remote is the Jiankou section, which is largely unrestored, so book with an experienced group like Beijing Hikers or Wild Great Wall.

The Rossio railway station was designed between 1886 and 1887 by Portuguese architect José Luís Monteiro. It makes connections with the village of Sintra, and the 2,600-meter tunnel was excavated under the city. It is considered one of 19th-century Portugal’s most important works of engineering. It has a beautiful Neo-Manueline façade, where two intertwined horseshoe portals stand at the entrance, a clock sits in a small turret, and the sculptural decoration is abundant. Inside you can now find a Starbucks, Lisbon Destination Hostel, and a souvenir shop.

One of the most popular anchorages in the BVI, Cane Garden Bay is home to a lively boating community. It makes a great day trip, whether you arrive by land or by sea. In this scenic cove, calm blue water laps a gentle arc of blinding white sand. Open-air beach bars offer lounge chairs and rum drinks; a few shops sell souvenirs, along with provisions for the sailors coming in off their boats to stock up.

Cruising through Prince Christian Sound, passengers only see one sign of human habitation against the stark landscape: the tiny Inuit village called Aappilattoq, which means “sea anemone” in the local Greenlandic Inuit language. Aappilattoq sits perched at the edge of the water with towering mountains all around, making the village virtually inaccessible by land. The cluster of colorful houses is home to around 100 people, rugged individuals who mostly fish and hunt the harsh terrain as they live isolated from the outside world (except for the occasional arrival of a boat or helicopter).

This long stretch of upscale shops north of Palermo’s historic center has been called the Champs-Élysées of Sicily. If you’re looking for the best spot to take a stroll while perusing luxury brands and fashion boutiques, the Via della Libertà is the place to do it. Dress up.

A visit to the Palazzo Mirto offers the rare opportunity to see the interior of a classic Palermo palace as it was during its extravagant heyday. Located in the historic Kalsa district, Palazzo Mirto was home to the prominent Filangeri family for 400 years; the last remaining member donated the palace to the city in 1982. The vast library, the Chinese smoking room and the cavernous ballroom still have their frescoes, chandeliers, tapestries and opulent furnishings intact.

Take a break from the city’s frenetic energy with a visit to the Palermo Botanical Garden, just south of the port next to Villa Giulia Park. Established in 1786, the 10-hectare (25-acre) gardens contain plants from around the world: Southeast Asian palms, coffee and papaya trees, even cotton plants and sugarcane. A terraced pond blooms with lotus and water lilies, while the ruins of the 14th-century Church of Saint Dennis can be found amid the greenery.