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A week in San Antonio provides plenty of time to explore the city’s many historic landmarks, wander the River Walk, taste your way through the Pearly Brewery, and head out to Hill Country on a day trip or, perhaps, an overnight.

Philadelphia is known for its markets, but you can also find books, music, art, antique treasures, Pennsylvania handicrafts, and Whirly Berley Bars in the City of Brotherly Love. Whether you’re looking for high-end boutiques or vintage funk, Philly’s got you covered.

Kampa, in Prague’s charming Malá Strana district, is Prague’s largest island. Tucked between the Vltava River and the romantic Čertovka channel, the island’s park comes alive in the warmer months with picnickers, dog walkers, and friends gathered on the greenery desperate to catch up on their vitamin D. With direct views of the Vltava’s roaring rapids and the city’s famous Charles Bridge, Kampa is also home to the Kampa Museum, a former mill turned modern art museum dedicated to 20th-century Central European art. Artist David Černý’s gigantic crawling babies are outside the building, while the inner courtyard and galleries showcase other freestanding works, sculpture, paintings, and photographs.

A city built on seafood and rice, Charleston remains focused on its abundance of local fish and produce, especially as its restaurant scene continues to boom. This once sleepy Southern town is now an international dining destination.

Portland has long been one of America’s culinary “it” cities and that won’t change anytime soon. The city’s cooks do so many things so very well: from doughnuts to dishes that focus on seasonal and locally-sourced ingredients. Eat around the world without leaving the city limits with visits to the legendary food cart scene as well as top spots like Ava Gene’s, Kachka, and Hat Yai (their Thai fried chicken will make you want to move to Portland). Pull up to one of these restaurant tables and you’ll find yourself challenged and delighted and definitely eager for more.

Scores of sci-fi geeks, space gazers, and physicists worship this iconic particle physics lab. Founded in 1954, CERN (Conseil Européen pour la Recherche Nucléaire) is located just five miles (8 km) west of Geneva and is open to the public. The lab’s main attraction is the Large Hadron Collider, a particle accelerator that shoots protons around an almost 17-mile (27 km) circular tube, which in turn creates new matter. Other permanent exhibitsl emphasize CERN’s current projects. Two-hour guided tours in English require advance reservations up to 15 days ahead and require a photo ID.

Nanortalik, which means “the place with polar bears,” is the southernmost town in Greenland, located on an island of the same name. Founded in 1797 as a trading depot at the mouth of Tasermiut Fjord, the town is currently home to approximately 1,000 people. Although the island is named for polar bears, the chance of seeing these furry giants is fairly slim. What you will find, however, is a place of majestic beauty and friendly, welcoming residents. From the nearby Tasermiut Fjord, where rocky summits rise above a narrow glacial inlet, to the Qinngua Valley—the only forest in all of Greenland—Nanortalik is surrounded by natural wonders. Culturally there is just as much to experience. For history buffs, the Nanortalik Museum explores native, Old Norse and European colonial history as it shaped Greenland, with nine historic buildings and the world’s oldest umiak (sealskin boat). To appreciate the richness of Greenland’s traditions, be sure to attend a local choral concert where you’ll hear a unique blend of musical disciplines unlike any you’ve heard before.

Seoul is a vast metropolis with an efficient public transportation system. In addition to major sites like temples, museums, and palaces, the city boasts unexpected gems including nature trails and mazes of alluring backstreets.

Colorful and chaotic, at least by Tahitian standards, Papeete is Tahiti’s capital city and a cultural hub worth exploring. It’s undergoing a bit of a renaissance these days, with an infusion of graffiti street art brightening once gray buildings. Sip cappuccino at a chic sidewalk café while soaking up a rapid-fire French soundtrack, shop the vibrant market for everything from flawless pearls to bright parae, or catch a world-class dance and music performance.

If the only Polish foods that come to mind are kielbasa and pierogi, you probably already have a pretty positive attitude for exploring the cuisine of Kraków. From the simple pretzel bought on the street, to the exquisite dessert at one of the medieval city’s fine-dining restaurants, to a robust lunch eaten in a communist-era milkbar, you will find much to love in the food here.

From folk art to cowboy boots, San Antonio’s rich history and geography continues to inspire local artisans. There are shopping destinations both enclosed and open air all around the city to please every taste, from the Shops at La Cantera to Blue Star Contemporary Arts and a nearby flea market that features a giant sign shaped like armadillo. Save Sunday mornings for brunch and shopping along the River Walk.

Over a long weekend, you can enjoy many of Philadelphia’s historic and cultural attractions. You have markets to peruse, doughtnuts to inhale, world-class museums, and food for days. Keep in mind, with only three days in Philly, you will just scratch the surface of what the city has to offer.

Philadelphia boasts endless options for family visits. Hit the historic sites and the Art Museum (for photos at the Rocky statue and a run up the iconic steps, natch). Then hang out with some dinosaurs and have some doughnuts. Here is our insider’s list of kid-friendly stuff in the City of Brotherly Love.

For decades, Buffalo was home to several corner pubs and a handful of breweries, but as the population shrank, so did the bar count. Thankfully, with the city’s resurgence came a slew of local taverns, high-end cocktail bars, cozy coffee shops, and late-night clubs that, together, have created a better-than-ever drinks scene. From Elmwood Village to Hertel, there’s no shortage of places to imbibe in Buffalo these days.

Painted by Michelangelo between 1508 and 1512, the frescoes on the Sistine Chapel ceiling are considered some of the finest art ever produced. These religious paintings include nine scenes from the Book of Genesis, of which The Creation of Adam is undoubtedly the most iconic.