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Located in a historic trolley barn, the original Big River Grille and Brewing Works is conveniently located within walking distance of the Tennessee Aquarium and other popular attractions. Inside you can see the brewery behind a glass wall, where beer is made right before it comes to you. Big River’s beers have won countless awards and none more so than the Iron Horse Stout. The Southern Flyer Light Lager and Big River Vienna Lager are also favorites. The extensive menu of pizzas, sandwiches, burgers and entrees pairs well with the beers.

I’ve been all over the California coast and Point Lobos is my favorite place to hike. We have hiked every trail in this reserve and never tire of this magical place. You can see many animals, such as sea otters, seals, elephant seals,sea lions, squirrels and deer that are often in little pockets near the trails. Most of the hikes are easy to moderate, you can make them longer by combining them or just hike smaller parts. There is a whalers cabin that has been transformed into a little museum at one end of the reserve.

The bustling corner of Walnut and 17^th streets is anchored by the Latham, a stone-and-brick tower built in 1907 as luxury apartments for moneyed Philadelphians. While other Center City historic structures met their demise in the late 1960s, a group of investors doubled down on the stately building, transforming it into Philadelphia’s premier business hotel in 1970. The prestigious address completed a top-to-bottom renovation in 2011, bringing the Latham firmly into the 21st century while preserving period artifacts and style.

True to its apartment roots, arriving at the hotel is more like entering a tony doorman building, and the Latham’s residential roots bestow spacious guestrooms with tall ceilings, bay windows, and big bathrooms. Gold and gray hues are complemented by pops of blue, while big bathrooms keep it simple with a tub/shower combination.

A historic New York state resort, Mohonk Mountain House first opened in 1869 in the Hudson Valley, about 90 miles from New York City. This Victorian castle has welcomed five U.S. presidents (including Bill Clinton) in addition to countless artists, authors, and actors. Surrounded by thousands of acres of nature, the resort is perched on a cliff overlooking Mohonk Lake. Guests travel specifically for the dramatic, vibrant fall foliage and expertly manicured gardens. Rates are all-inclusive and comprehensive—all meals and activities are included for a single nightly rate. Yoga classes, boating, tennis, horseback riding, and rock climbing are all popular activities. During the winter, ice skating and cross-country skiing lure guests into the great outdoors. Rooms with wood-burning fireplaces and a huge spa with heated indoor and outdoor pool create a peaceful retreat.

Frenchmen Street is, more or less, the local-music version of Bourbon Street. It also has its share of tourists trundling about with go-cups in hand, but they’re drawn more by the music than the drink. Plan to spend an evening (things start to pick up around 8 p.m., earlier on weekends) along a three-block stretch of small, informal clubs where there’s often no cover (give generously and give often when the bucket comes around), or at most $5 or $10. Notable clubs include the Spotted Cat, the Maison, Blue Nile, D.B.A., the Apple Barrel, and Snug Harbor. Earlier in the evenings, there’s often an impromptu brass band at the corner of Chartres and Frenchmen. Between sets, take a moment to browse the night art markets, the largest of which is next to the Spotted Cat.

The city’s most famous snowbird, architect Frank Lloyd Wright, spent winters at his home and architecture school in the Sonoran Desert. Taliesin West brings the horizontal lines and organic materials of Prairie School design to the desert landscape in low, skylighted buildings. Behind-the-scenes tours visit the pop-up structures that students have designed as living spaces amid the barrel cactus and paloverde trees.

Despite being northern Colorado, Steamboat Springs offers belly-filling home-style southern cooking at the Low Country Kitchen right on Lincoln Avenue. Dig into the classics (without the greasy coating), like fried okra and buttermilk fried chicken, or go for the jambalaya or hush puppies. For south of the border–style grub, pop into Salt & Lime and head for the rooftop seating. Start with some loaded nachos then choose from a range of classic tacos and burritos; finish off with fresh churros. The menu changes frequently, with new and exciting dishes becoming available.

In the Napa Valley—and in Yountville, in particular—most hotels err on the side of sophisticated luxury. Which makes the North Block Hotel’s quirky style such a breath of fresh air. With the look of a Mediterranean town’s cobbled street, complete with lemon trees and hand-painted tiles, one of Napa’s few modern boutique hotels also displays quirky pieces like The Big Book of Boobs in its lobby. It’s hard to pass through the lobby without having a friendly concierge hand you a glass of bubbly, and the umbrella-shaded “sidewalk” tables seem like places you’d actually while away the hours over bottles of good wine with good friends. The trendy restaurant channels a midcentury Italian cool that’s more Fellini than Michelangelo, unlike most Napa wineries’ inclinations, and the fact that it doesn’t have a Michelin star is actually a vote in its favor in sometimes stuffy, star-saturated Yountville. Of course, the spa is still as luxuriously pampering as any in wine country, and the understated rooms are as decked out with designer amenities as they ought to be—and you might actually be having enough fun to enjoy them.

Chef Tory McPhail was recently named James Beard’s Best Chef South and his forward-looking take on Creole classics keeps this New Orleans institution, which has launched the careers of the likes of Paul Prudhomme and Emeril Lagasse, current. Still, you can’t go wrong with classics like the turtle soup, gumbo, and bread pudding souffle. On Saturday and Sundays, there’s more pomp than usual, including a jazz trio that makes its way from table to table, but weekday lunches are nearly as iconic and, thanks to 25-cent martinis, a good reason to have a midday cocktail.

Frank Altamura took his time renovating the old Italian grocery store — where he remembers shopping as a child — at the north end of Yountville. His dream was to turn the partly dilapidated building into a casual restaurant with great pizza and Napa Valley wine where locals would love to eat. His dream came to fruition when Ciccio opened its doors in 2013. The menu is simple, straightforward and ever-changing based on what Altamura is bringing in from his Napa ranch, where he also grows Cabernet Sauvignon, Nebbiolo, Sangiovese and Negroamaro for his eponymous wine. Chef Polly Lappetito (former Executive Chef at The Culinary Institute of America) traveled far and wide in search of the perfect pizza crust, but her’s is in a category all its own — prepared in a hand-tiled, wood-burning pizza oven imported from Italy.

Not just a wonderfully large bookstore—although it is that—the University Bookstore is also a café and a fantastic gift shop. The two-level bookstore has a textbook section for students and general fiction and nonfiction for the public, as well as a good selection of art supplies and kids’ crafts and toys downstairs. The large front room is devoted to all things fun: journals and stationery, makeup counters, bags and silver jewelry, candy and novelty items, soaps and housewares. If you’re a Husky fan, they have plenty of team merchandise, too. The Seattle bookstore has frequent author reading events (shown above: a cupcake-loving dragon sketched by illustrator Jackie Morris during a Robin Hobb reading), so check their calendar and see what’s going on while you’re in town.

Part sustainable residential building, part eco-friendly lodge, the El Moore has been witness to Detroit’s turbulent history. The restored Victorian building boasts rooftop urban cabins, expansive suites, and bunk-bedded garden view rooms, covering various price points. Rooms feature reclaimed wood and subway tiles as well as ash paneling, geothermal heating, and solar paneling.

The Gin Joint opened in 2010 and was Charleston‘s first real dedicated craft cocktail spot. Five years later, it’s still going strong with its creative drinks menu (including a “bartender’s choice” option for the patron who wants a surprise) and great bites, from gourmet soft pretzels to “cornbread and milk” for dessert.

With its pressed tin ceilings, exposed brick walls, and extensive cocktail menu, The Belmont could easily be mistaken for a bar in Brooklyn. But the laid-back vibe is pure Lowcountry. The Belmont is one of Charleston‘s first craft cocktail bars, and it’s still one of the best. No reservations.

Top chefs clamor for the hams cured at Bentons, an unassuming smokehouse in Madisonville. Online orders can take more than a month; instead, drop in for a tour and take home some bacon. This appeared in the May 2014 issue.