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Huacachina is a coastal desert located in the Ica region. It holds one of the few oases in the whole region: a blue-green lake amid huge sand dunes under a beautifully clear sky. Take a dune buggy so that you can ride all over the dunes before riding a sand board down. This is the definition of a touristic little town, and it is definitely worth a visit. You’ll find some nice hostels ands lodges where you can stay overnight right in the middle of the oasis. Huacachina Oasis is a short four-hour drive from Lima, and there are also plenty of buses that will bring you here.

Little-known fact: New Orleans was the first place in North America to license pharmacists (starting in 1769, when the city was still under Spanish rule). After Louisiana became a territory, the U.S. governor extended the requirement, also decreeing that pharmacists take a three-hour licensing exam in order to practice. And no wonder illness got such attention—the city was arguably the least healthy place to live on the continent; it was riddled with yellow fever, malaria, and dysentery. This dark but fascinating history is explored in this atmospheric 1822 town house, which was once the home and shop of Louis J. Dufilho, the first licensed pharmacist in the city—and hence in the country. Exhibits include apothecary jars, tools of the trade, and leeches. (Yes. Leeches.)

The Evergreen Brick Works, a reclaimed quarry in the lush Don Valley, is a showcase for sustainable and green living, as well as for urban design. A community has been established in this once-derelict industrial site and former landfill. Toronto’s largest farmers’ market sets up shop on Saturdays, and spotlights food from all over the province. On Sunday, the market shifts its attention to crafts. A full schedule of activities and diversions make this a perfect weekend escape: There’s a children’s garden (with weekly programming), bike trails and rentals, and a hike that leads to a rewarding view of the city’s skyline.

If you love art in all its many forms, the Museum of Fine Arts (MFA) in Boston is a ‘must-see’ destination. They have a great collection of Impressionism and Asian art works, from Monet and Van Gogh, to Chinese furniture and Japanese paintings, as well as the Egyptian collections. In addition, their newly opened west wing contains many stunning pieces of American art. Besides the arts, there is a cafe, a restaurant, gift shops of course, and a mini cinema for special shows. To get there: The MFA has its own subway stop called, what else, the MFA. If you drive, there are parking garage options as well. You can easily spend half a day here—or more!

Housed across a 1940s mansion and modernist tower, Casa Fayette is a stylish boutique lodging inspired by Guadalajara hometown hero Luis Barragán. With the architect in mind, Milanese interiors firm Dimore Studio designed the hotel’s 37 rooms in a Mexican palette of artichoke, salmon, and burgundy, adding a mix of custom and European furnishings by the likes of Pierre Frey and Michael Thonet. Downstairs, public spaces take on a global-chic aesthetic informed by the surrounding Lafayette neighborhood. Graphic cement tiles line the pool and spa area, while a glam brass-and-wood bar complements tropical-palm-patterned seating in the restaurant.

Petra flourished more than 2,000 years ago, trading with Rome as an equal before being abandoned after a series of earthquakes in the 4th and 6th centuries C.E. It wasn’t until the 19th century, when European explorers “rediscovered” it, that the ancient city returned to the public consciousness. Now, visitors can walk down the narrow canyon of the siq to the city entrance—as dramatic an approach as any to a tourist attraction on the planet. The canyon opens up onto the carved facade of the Treasury, Petra’s most iconic site. From there, you can explore the cliffside tombs with their colorful bands of sandstone, the Street of Facades, and the amphitheater hewn from living rock. The ancient center lies some distance off, along with the splendid old Monastery, which sits at the top of a steep but rewarding climb. Consider buying a three-day ticket and visiting at different times of day to enjoy the changing light—early in the morning is best for the Treasury, while late afternoon is better for the Royal Tombs.

Formerly known as Bastakiya, the Al-Fahidi Historical Neighborhood was preserved in the mid-2000s amid the city’s rush to modernize. As you wander around this district off Dubai Creek, you’ll see teahouses, art galleries and private homes on narrow pedestrian alleys. The area was settled in the 19th century by Arab merchants from Persia. In those days, wind towers called barjeel were used as a form of air-conditioning.

CoLAB, one of Rio’s coolest venues, may serve breakfast all day but it is much more than a breakfast joint. The tight space starts the day as a coffee house, then morphs into a cafe in the afternoon, and as the night falls, it becomes a bar. In addition to sundry coffee, granola, and artisanal baked goods, there are brunch items on the menu, as well as several curries, “street food” prepared with care (the falafel is especially recommended). The drink menu includes a range of nonalcoholic choices like kombucha and lemonade, as well as beer, and both classic and creative cocktails. A recent expansion introduced an additional small space for live music, a chill second floor, and a terrace. A performance schedule can be found online.

Cruising through Prince Christian Sound, passengers only see one sign of human habitation against the stark landscape: the tiny Inuit village called Aappilattoq, which means “sea anemone” in the local Greenlandic Inuit language. Aappilattoq sits perched at the edge of the water with towering mountains all around, making the village virtually inaccessible by land. The cluster of colorful houses is home to around 100 people, rugged individuals who mostly fish and hunt the harsh terrain as they live isolated from the outside world (except for the occasional arrival of a boat or helicopter).

Open every day for lunch and dinner, this casual spot next to the Fort Myers Beach pier has been around for more than two decades. Grab a spot on the outdoor terrace overlooking the sand for mango ceviche made with Gulf shrimp and bay scallops, or the more-adventurous gator tail platter. For an extra lively scene, go during happy hour at the grill or the twice-daily live music at Famous Blowfish Bar. With an always-on-vacation vibe, this spot keeps the party going from early until late.

La Ménagère is simultaneously a breakfast spot, a tapas and cocktail bar, a flower shop, a café, a housewares store, and a restaurant. The large space, once home to a famous Florentine home-goods emporium, is now a ramble of beautiful rooms that serve many needs. The bright and airy bar area is the site for breakfast, lunch, aperitifs, and cocktails, while dinner can be eaten in several of the other charming rooms, including a narrow passage set with a long communal table. There’s even a downstairs space where live music is played a few nights a week.

This 2.5-kilometer (1.5-mile) promenade along the vast Guayas River is part public park, part urban playground filled with restaurants, cafés, shops, a clock tower, an IMAX theater and even a Ferris wheel. From the docks, small boats leave on river tours or head to Santay Island, a wildlife refuge on the eastern side of the river. At La Rotonda, a statue of Simón Bolívar and José de San Martín commemorates their meeting in Guayaquil after the liberation of Ecuador from Spain.

The towering 60-kilometer-long (37-mile-long) Pío XI Glacier, also called Brüggen, is the granddaddy of all Patagonian glacial ice fields. Located in Bernardo O’Higgins National Park, the glacier takes a 90-degree turn on its way down to the sea and is almost twice as large as Singapore. Glaciologists are not entirely clear on why Pío XI is the rare glacier—along with Argentina’s nearby Perito Moreno at the base of the Torres del Paine cordillera—that is growing rather than receding.

This botanical wonder is home to thousands of native plant species, including heliconias, hibiscus and bromeliads. Guests enjoy strolling around the three-hectare (seven-acre) grounds, where hundreds of palm trees tower over creeks and tiny hummingbirds flit among the lush foliage. An aerial walkway suspended 15 meters (49 feet) high in the canopy gives visitors views of the Balata Garden, the mountains and Fort-de-France Bay. There’s also a fine old plantation house on the grounds.

Les Houches bills itself as Chamonix’s go-to resort for families. And nothing encapsulates its relaxed, enjoyable atmosphere more than its outdoor ice rink. Located in the heart of the village, this popular spot not only provides a beautiful backdrop of Mont Blanc (check out the late-afternoon illuminations), it’s also free to use. Once the last shards of crimson glow have left Europe’s famous mountain range, skaters carve along under the stars—as late as 11 p.m. on Wednesdays and Fridays, with music playing throughout. Note: The rink is open from late December through the end of March, and ice-skate rentals cost € ($3.50).