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Founded in 1913, this famous botanical garden was the first in the world dedicated to its country’s own flora. The spectacular, 90-acre plant haven forms part of a nature reserve that borders Table Mountain National Park. Besides numerous gardens and forests—some of which you can traverse on high via the futuristic Boomslang (Tree Snake) walkway—Kirstenbosch has a greenhouse, a restaurant run by the popular Moyo group, and a nursery for green thumbs who want to take a piece of the garden home with them. Spend five minutes here and you’ll realize why Kirstenbosch’s displays at the Chelsea Flower Show in London often win gold.

Up until 2004, Switzerland’s iconic furry friends—St. Bernard dogs—were bred at this monastery and hospice. While the canines have been relocated, the Great St. Bernard Hospice, which sits on a barren, treeless plane at 8,100 feet, is still an active monastery run by Augustinian monks. The steep four-mile ascent from the valley is a killer on foot, but still doable—on groomed trails in summer and on snowshoes in winter. Inside, monks greet you and show you to communal tables in the stone dining hall where vegetable soups are served with hunks of Bagnes cheese, thick slices of brown bread, and honey-sweetened tea (or a carafe of red Dôle wine produced in the Valais region just below, which seems to be the more popular option). Don’t miss the odd museum, displaying local taxidermy, ancient coins, and maps once used for Alpine crossings; the 800-year-old crypt is allegedly stuffed with the bodies of ancient travelers who didn’t survive the journey. A register of “Les passants célèbres” includes Charlemagne, Napoleon, and Alexandré Dumas but omits Charles Dickens, who lived nearby for a summer.

Take a break from the city’s frenetic energy with a visit to the Palermo Botanical Garden, just south of the port next to Villa Giulia Park. Established in 1786, the 10-hectare (25-acre) gardens contain plants from around the world: Southeast Asian palms, coffee and papaya trees, even cotton plants and sugarcane. A terraced pond blooms with lotus and water lilies, while the ruins of the 14th-century Church of Saint Dennis can be found amid the greenery.

This cultural center with studios and offices for musicians is also a restaurant that focuses on hot dogs (yes, and they are very good!) and a music venue for alternative and world music. Totally relaxed with a nice little garden outside.

Simplicity reigns at The Charter Oak, the gamechanging restaurant owned by Christopher Kostow (who also helms the kitchen at The Restaurant at Meadowood). The family-style menu by chef Katianna Hong features “elemental” cooking, with dishes that highlight only one or two ingredients at a time. The best representation of this is the crudités, raw vegetables from the restaurant’s farm, served on a bed of crushed ice with a side of fermented soy dip. Another example? Crudo of kanpachi with grilled Rangpur lime and herbs. Most of the menu’s larger dishes are seasonal and prepared in a hearth at the center of the restaurant. Highlights include roasted pork shoulder with spiced molasses and winter squash, and beef rib grilled over cabernet barrels and beets dried over the fire. The most Instagram-worthy part of the meal may be the moment the server explains where to find the silverware—forks, knives, spoons, and napkins are stored in hidden drawers on the side of each table. During warm summer evenings, precede your meal with a few rounds of handcrafted cocktails in the open-air courtyard out front. The happy hour of half-priced beers and $3 shots of Fernet-Branca can’t be beat.

The village of Monticello just outside of L’Île-Rousse would be worth a visit just for its wonderful coastal views, which come courtesy of its perch 213 meters (700 feet) above the sea. Like many towns here in the Balagne region it’s also known for a gorgeous church: Saint-François-Xavier, which has two fine Baroque chapels. Further down a mountain road that passes through groves of olive trees, Santa-Reparata is a village with another handful of historic churches and chapels.

There’s something dark and offbeat about the Jura, Switzerland’s 26th and youngest canton. Located in a distant corner of the deep, wooded Doubs River Valley bordering France, the town of St. Ursanne embodies some of the canton’s surprising remoteness and offers a glimpse of a medieval village untouched by modernity. According to legend, the village, perched on the banks of the Doubs River, was founded by the 7th-century Irish monk Ursicinus, who was banished from Burgundy and became a hermit here. Arriving visitors will first have to cross the four-arched Doubs Bridge before getting to see the town’s medieval edifices, including 14th-century half-timber burgher houses and a 12th-century collegiate church. Climb the 190 steps to access the St. Ursicinus hermitage or a go on short, signposted hike to some castle ruins and the Doubs Nature Park.

The magnificent blue-domed cruciform Russian Orthodox church was elevated to cathedral status in 2001. It contains the relics of Saint Herman, a Russian-born monk who helped establish a bilingual school for the native peoples of Kodiak and later cared for orphans on remote Spruce Island. A lamp burns continuously above his reliquary and priests still anoint sick and suffering pilgrims with its holy oil. Also on display are the saint’s skufia (a soft brimless cap) and an iron cross he secretly wore on his chest.

Climbing uphill from the port, the streets of Vigo’s casco vello, or old town, retain their authentic flavor because locals still live above the neighborhood shops, taverns and tapas joints. The narrow streets open up to sunny little squares, including one at the cathedral, Santa María de Vigo (also called La Colegiata). Note the street names in the casco vello: They still often correspond to the wares offered there (buy a hat on Rúa Sombrereiros or baskets on Rúa dos Cesteiros).

Located in Sainte-Anne, Karukera Land is a recreational park that makes for a fun and self-contained outing for families. Learn about the island’s flora with a walk through the tropical gardens, and visit a range of Caribbean fauna, from goats to peacocks. Active kids will love the acrobatic course, trampolines, and swimming pools with multiple toboggan slides. There’s plenty to entertain grown-ups as well, including billiard and ping-pong tables, a mini-golf course, and spa relaxation area with massage hut.

Hilton’s reentry into the heart of Paris is nothing short of majestic. After a $50 million design overhaul, the 125-year-old hotel, made for the 1889 World’s Fair, has been revived to its 19th-century splendor with a contemporary twist. Formerly the Grand Hotel Terminus and the Concorde Opéra Paris, the property’s landmark status—with its Haussmannian facade and elegant public spaces—demanded it be painstakingly preserved. Among the restored, original elements, the most awe-inspiring are the Corinthian columns, chandeliers, balustrades, hand-painted frescoes, and marble and mosaic tiling. Fortunately, the bar takes pride of place among them, making it the ideal spot to start your stay with a cocktail or glass of wine.

The style in each of the rooms breaks with the traditional stark-white modern codes of most business hotels. Here it incorporates warm accent colors and textiles. With few heritage elements left to preserve, the sense of place is woven in with custom etchings of iconic Paris scenes hung behind each bed. But you won’t be spending much time here, as the action happens in the grand salon.

This pink-marble waterfront edifice in Piazza San Marco dates back to the 14th century, when it was the residence and seat of government for the doges (rulers) of Venice. Today the ornate Byzantine- and Moorish-influenced Gothic Palazzo Ducale is a symbol of the city, and serves as a museum hosting some of Venice’s most important art, including the famous Bacchus, Venus, and Ariadne masterpiece by Tintoretto. It also runs the popular Secret Itinerary and Doge’s Palace Hidden Treasures tours. After you’re done, treat yourself to a glass of wine in the small on-site bistro, with windows looking onto the Grand Canal adjacent to the Bridge of Sighs.

The cathedral in Amalfi, with its glittering gold mosaic facade and colorful Majorca-tiled dome, dominates the main piazza. Construction on the cathedral began in the 9th century, and centuries of additions and renovations are revealed in the mashup of Moorish and Norman Romanesque styles present. Climb the 62 steep steps in front to admire the enormous bronze doors that were cast in 11th-century Constantinople. Inside, the crypt holds the relics of St. Andrew the Apostle, the patron saint of Amalfi. Through the cathedral’s portico, you can enter the Cloisters of Paradise, a 12th-century arcade bordered by 120 columns surrounding a garden. This peaceful space was created as a burial place for the noble families of Amalfi.

This is a local favorite and the ultimate hangout for musicians in Gothenburg, a store where you can spend hours talking to owner Bruce Ems and browsing among the Hagström guitars and synthesizers. The name MUG on the sign is short for Musik Utan Gränser—Music Without Borders.

While many of Napa’s other bakeries are known for their sweets, this one, with locations in Yountville, Napa, and St. Helena, is known for something entirely different: bread. In particular, the Model Bakery’s English muffins have achieved nationwide fame and appeared on Oprah’s “Favorite Things” list. The breads are so popular that you have to arrive by 9 a.m. on weekend mornings if you want them fresh. Model bakes other types of bread as well, including levain, harvest wheat, and sourdough, as well as French baguettes and walnut bread. Even the bakery’s focaccia is off-the-charts good. In addition to all these carbs, the bakery also offers hot sandwiches, salads, and pastries.