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After years of development, San Antonio’s revived Pearl Brewery district is now a hotbed of activity, with an array of restaurants, shops, and residential buildings, plus an outpost of the Culinary Institute of America housed in a former 19th-century brewery. At its core is the 146-room Hotel Emma, set in the complex’s former brew house, and named for the wife of the original brewer. Envisioned by noted design firm Roman and Williams, the décor melds salvaged items with lots of rich woods, buttery leathers, and handwoven textiles, resulting in spaces that are warm and cushy. Adding to that cozy feel are higher-level rooms that feature claw-foot tubs or fireplaces, a bi-level library stocked with over 3,700 tomes, and the clubby Sternewirth Bar, which serves potent cocktails in an old fermentation silo. Food is also a focus here—in addition to Chef John Brand’s Supper, serving farm-fresh New American fare, and Larder, a café and gourmet market set in the former fermentation cellars, the hotel offers a Culinary Concierge to help connect guests to the best of San Antonio’s booming food scene.

Charleston’s four-block City Market is a historic landmark (one of the oldest in the country, rivaled only by Baltimore’s Lexington Market) and an essential stop for locally made souvenirs and snacks. Pack up your sweetgrass basket (a traditional Gullah handicraft) and check in for the night across the street at the Market Pavilion Hotel. The hotel has all the plush trappings—Italian marble bathrooms, Hermes toiletries, treats at turndown—one could ask for in the French Quarter, topped off by a rooftop bar and pool with enviable views of the harbor and bustling East Bay street. On a particularly hot Southern night, you might cool off with a nitrogen-infused cocktail before sitting down to a steak dinner at Grill 225, which serves only aged, USDA-Prime meat. The hotel is a member of the Leading Hotels of the World and the restaurant is one of a dozen Great Steakhouses of North America.

The Post Hotel & Spa is set in the heart of the pristine Banff National Park, surrounded by the Canadian Rocky Mountains and overlooking Lake Louise. The original log-walled lodge—opened in 1942 as the Lake Louise Ski Lodge—has stone fireplaces and a cheery red alpine roof, and the numerous add-ons, extensions, and renovations over the years have preserved and accentuated this rustic design. This is further enhanced by the hotel’s interior color palette of burgundy and neutrals, and set off by luxurious touches such as overstuffed couches and Egyptian-cotton sheets. The accommodations include intimate cabins for two and a 3,000-square-foot mountain chalet ideal for groups and families. Just minutes away from one of Canada’s largest ski areas and blessed with an abundance of perfect powder each season, the Post Hotel & Spa is popular with skiers and boarders from across North America; in summer it attracts outdoor enthusiasts keen to explore the myriad treasures of the national park. It has been a Relais & Châteaux property since 1990.

Set amid the mangrove swamps, coastal lagoons, and stretches of coral reef in Portobelo National Park, this Design Hotels property features just five colorful villas. The “houses” range from a small, one-bedroom retreat nestled near a waterfall, to an over 8,000-square-foot residence spread over two floors. The whole property is awash in a kaleidoscope of vibrant hues, from the bright interiors with their boldly patterned tiles, decorative fabrics, and local artwork, to the multi-colored lounge chairs surrounding the infinity pool, which seems to merge seamlessly with the turquoise Portobelo Bay. Those seeking adventure can take a deep-sea dive to explore the wreck of a C-45 airplane, while guests looking to relax can book an outdoor massage on the hotel’s century-old barge.

Part of Museum Hill, the Wheelwright, founded in 1937 by Mary Cabot Wheelwright, is a small private museum with a stellar collection of pottery, sculpture, baskets, weavings, and historic and contemporary works by Native American artists. The hidden gem remains the lower-level Case Trading Post with a fantastic selection of jewelry, kachina dolls, weavings, and pottery from over 200 Native American artists.

Cajones are the small shallow canyons on the Chame River, favored by nature lovers and thrill-seekers alike. The canyon’s walls are eroded in places in delineated strata that reveal the Isthmus of Panama’s geologic history. You can hike or rappel along the canyon, or swim, float, or tube down the river, through eight pristine pools that invite general splashing about. To get there, drive the Pan-American Highway west from the capital, then merge onto the Bejuco-Sorá road. Los Cajones is twenty minutes away by 4x4 (you can park at the entrance and, for a small fee, take a shuttle service). There are no facilities inside the park at all, so come prepared with food and water.

Fans of the Montage brand’s Laguna Beach and Beverly Hills flagships will love this mountain version, a ski-in, ski-out hotel wedged into the head of Empire Canyon. The sprawling, Craftsman-style manor debuted in 2010, solidifying Deer Valley’s standing as one of North America’s most luxurious ski resorts. Service shines, starting with the “Mountain Host,” who greets guests in the majestic lobby rotunda. Up the grand staircase, the full-service Vista Lounge acts as a communal living room, with vaulted ceilings, exposed wood beams, floor-to-ceiling windows, and leather furnishings gathered around limestone fireplaces. To further entertain guests, there’s also a museum-quality collection of Western art, including Carl Runguis panoramas, John James Audubon prints, and Frederic Remington portraits.

The hotel’s X-shaped footprint means nearly every room has small deck with mountain or valley views. Averaging around 600 square feet, large guestrooms are airy and inviting with lofted ceilings and soothing natural hues. Remote-controlled gas fireplaces are the centerpiece of each room, though the bath suite with heated limestone floors, marble vanity, rain shower, and soaking tub could occupy your entire evening.

Chattanooga’s Hunter Museum of American Art is set against a cliff overlooking the Tennessee River. If the view doesn’t draw you in, it will be the collection of American art from Winslow Homer to Andy Warhol. The museum is made up of a historic mansion, pictured above, a modern 1970s structure and a sleek contemporary building that looks like at any moment it could plummet into the water. Admission is $10 for adults and $5 for children and free on the first Sunday of every month.

Come for the drinks and stay for the music at the The Royal American. This “hole-in-the-wall” bar along Morrison Drive gets you up close to hip bands while drinking a beer, a signature punch, or the house made cinnamon whiskey, and dining on pub comfort food. You’ll want to look at the cool décor that includes a refurbished Wurlitzer jukebox and paintings on the ceiling of our own “Royal Americans”, such as Walt Disney, Frank Sinatra, Lucille Ball, Sitting Bull and Abraham Lincoln.

Founded more than a century ago, the US Grant gracefully mixes its historic legacy with contemporary touches. Ulysses Grant Jr., the son of President Ulysses Grant, began construction on the property at the turn of the 20th century. A time capsule filled with family photos and newspaper articles that he left in 1907 is now part of the hotel’s permanent collection. Since opening in 1910, the hotel has played host to 14 presidents. For a dose of culture without leaving the property, check out the Celebration Fine Art Gallery, where you can view paintings, sculptures, glasswork, and ceramics by national and international artists.

Today, the US Grant’s prime downtown location in the Gaslamp Quarter is hard to beat. When you enter the Grand Lobby, crystal chandeliers and hand-loomed carpets provide a sneak peak of the elegant decor found throughout the property. Guest rooms impress with tall ceilings, Empire-style furniture, and commissioned French and Native American art. No detail has been left out; even the headboards—one-of-a-kind figurative drip paintings—are a work of art.

In France, many châteaux (a term that sometimes translates to “castle” but can also refer to an ornate, castle-like mansion) are open as museums. However, Domaine de Maffliers, a 19th-century château nestled in the countryside just 45 minutes north of Paris, gives travelers the rare chance to spend the night in one. Though centuries old, the bar, restaurants, and 8 guest rooms have been recently renovated after a fire destroyed much of the building in 2020.

The interiors of each guest room are unique from one another, but all of them exude opulence and luxury—from the velvet chairs and curtains to the freestanding bathtubs—that allow guests to immerse themselves in the grandeur of its history.

At Isla Colón’s northwest extreme, Bocas del Drago is one of Panama’s most picturesque spots, an idyllic place for relaxing, soaking up sun or just marveling amid powdery white sand and lush jungle greenery. And what other beach affords “swimming with starfish”? Enhance your adventure at great local Caribbean restaurants featuring wiggle-fresh delicacies at delightfully low prices. When the tiny beach at Boca del Drago gets tight, Playa Estrella is a nearby alternative.

A collaboration between two of Siem Reap‘s most stylish women, French-Cambodians Nathalie Saphon-Ridel and Sirivan Chak, Galerie Cambodge specializes in beautiful fair trade clothes and accessories made in Cambodia to the highest quality of workmanship. The women work closely with designers and artisans to source, design and produce natural, eco-friendly garments, accessories and gifts. Collections change regularly, however, you can expect to find anything from the lightest of cotton shirts and scarves that are ideal for Siem Reap’s sultry weather to sturdy handmade leather sandals that will survive years of temple scrambling. Not everything is made in Cambodia—the women have made a few exceptions, such as authentic Panama hats, direct from the source. Also handy for long days in Siem Reap’s blazing heat.

As obvious as it may sound, what sets Sanctuary apart from any other Scottsdale resort is location. Sitting on the north side of Camelback Mountain yet minutes from downtown Scottsdale, it has a balance of desert mountain isolation and easy access that no other Scottsdale resort can match. Since Sanctuary opened in 2002, the combination has especially appealed to publicity-shy celebs (Beyoncé and Jay-Z even stayed here while on their honeymoon). The views from the floor-to-ceiling windows in the adobe casitas look out at the mountain and across Paradise Valley. The casitas have wood-block floors, glass-tiled showers, and, in many of them, oversize tubs with romantic votive candles.

From 1903 to 1979, the Panama Canal and an area extending eight kilometers (five miles) beyond it on each side were an unincorporated territory of the United States. The Canal Zone was not only politically but culturally part of America, with towns that could have been plucked out of the Midwest except for the humidity and tropical foliage. Balboa was the administrative capital of the Canal Zone, with American schools, several Protestant churches with services in English and both an Elks Club and a Masonic Lodge. Many of the buildings, like the YMCA and the Panama Canal Administration Building, still stand. After 1979, the Canal was jointly administered by Panama and the United States for 20 years before being returned completely to Panama in 1999.