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Avenida Central was the city’s great commercial core in the first half of the 20th century; though its heyday has ended, the swarm of humanity packing into its various shops, bars, hotels, restaurants, and other businesses attest to ongoing vibrancy. The classic stretch extends from Plaza Santa Ana to Plaza 5 de Mayo, where art deco and streamlined moderne landmarks are still on view. El Banco Nacional, the former Kodak building, and “La Pollera”—thus nicknamed for the resemblance its balconies bear to the traditional full skirts of the Los Santos region—figure among them. These avenue blocks are pedestrian-only; peddlers and street vendors selling every imaginable snack and trinket abound.

Many temptations are under one roof at the Langham, New York, Fifth Avenue. This polished hotel bucks the trend of tiny Midtown hotel rooms with spaces that begin at 420 square feet and stretch up to apartment-style accommodations with full kitchens—an ideal setup for families. The style is modern and refined, from the sweeping staircase that connects the lobby to the Michelin-rated Ai Fiori restaurant of chef Michael White on the second floor. The hotel doubles as an art gallery for the work of American artist Alex Katz, whose bold figurative paintings hang on the walls throughout the hotel. There’s also Chuan Body + Soul, a day spa based on the principles of Chinese Medicine.

Though it’s mere minutes from the chaotic pedestrian street Nanluoguxiang, Dali Courtyard, in a charming brick courtyard house, is as tranquil as the nearby streets are buzzing. Dinner is a set menu here (from ¥150 per person), a small parade of dishes from southern Yunnan Province. Star dishes, like rubing (fried goat cheese), guoqiao mixian (“crossing-the-bridge noodles”), and anything with mushrooms, a food for which Yunnan is known, always make appearances. Other dishes include things like grilled fish colored in chilies, stir-fried wild vegetables, and tofu and mint salad. The food here is on the spicy side, so be sure to ask for it mild. If you’re a vegetarian or have dietary restrictions, have the information written down in Chinese and give it to your server before you order.

At the beginning of the 20th century, a physics professor in Massachusetts inherited a ton of money. He promptly headed for the South Pacific, settling there and founding what’s now the Harrison Smith Botanical Garden. Maybe Smith had a slight Noah complex: He brought in plants from around the world, which means an African flower might sit next to a South American fern. The problem is that he inadvertently killed off the native plants with his imports. Still, the garden is a lovely spot to wander around, a sampler box of world botany.

In 1934, architect Luis Barragán won a contest put on by the city of Guadalajara to design a park on former prison land, creating a gateway to the city center. Together with his engineer brother, Barragán based his design on functionalist, Art Deco, and California modernist styles, incorporating elements of red and yellow as a nod to French 1930s design. Although the park (originally named Parque Revolución but now referred to as Parque Rio, or Red Park) has undergone significant changes over the years, certain elements—the red-and-yellow benches, the kiosk, the fountain, and the mashup of 1930s and ’40s architectural styles that would come to define Barragán’s later work—are still intact.

Located 100 miles south of Santiago, the Colchagua Valley has in the past decade become one of Chile‘s wine hotbeds for the production of robust red wines. Stretching from the Andean foothills in the east through the coastal mountains to west, always following the Tinguirrica River, the valley is renowned for its “big” reds like Cabernet Sauvignon, Syrah, and Chile‘s flagship wine, Carmenere. The majority of the vineyards lie in the center of the valley around the small country town of Santa Cruz with its charming colonial plaza and several hotels. New vineyard plantations are also extending into the hillsides in prestigious sub appellations like Apalta nearby and to the west towards the sea. Besides red wine, Colchagua is also steeped heavily in Chile’s country traditions and cowboy culture as an agricultural valley, making it an ideal weekend getaway. For wine enthusiasts, every March during harvest the valley puts on its annual harvest festival during a whole weekend with tastings from valley wineries, regional food, music, dance, and local color.

The peak called Monserrate towers over central Bogotá and lends its name to the church that tops it. Perched more than 10,000 feet above sea level, the sanctuary—dedicated to the Passion of Christ—has beautiful gardens showcasing marvelous highland vegetation, and the city views from here are spectacular (sunsets are especially recommended). Ascend Monserrate by cable car, via railway, or on foot (this last is only for the fittest and those already acclimated to the altitude). That beautiful white house on the mountainside is Casa Santa Clara restaurant, a better-than-expected, special-occasion-suitable venue at which to try traditional Bogotá favorites like ajiaco, a thick potato-and-chicken soup.

Two of Manila’s most famous churches can be found in close proximity to each other within the historic walled city of Intramuros. The 16th-century San Agustin Church, a UNESCO World Heritage Site, is the oldest church in the Philippines and was the only building in Intramuros to survive heavy bombing in World War II. It boasts an impressive interior with trompe l’oeil effects, a Baroque pulpit and a majestic pipe organ, and the museum houses treasures of Old Manila. A few blocks away, the Manila Cathedral, restored many times since the original version was built 450 years ago, hosts religious artworks and sacred relics and was visited by Pope Francis in 2015.

Duffy’s calls itself a “bar that serves great food.” Its brand of fruity tropical cocktails (some served in ceramic skulls) and casual fare seems somehow perfect for a relaxing Caribbean vacation. The restaurant claims to have hosted “pirates, debutantes, nerds, and rock stars.” From the outside, Duffy’s looks unassuming, but inside the colorful tiki bar decor features standard elements, such as bamboo-pole siding, spruced up with maritime mementos from around the Caribbean.

Teshima’s Restaurant is a historic Japanese diner on the west coast of Hawaii Island in Kealakekua. Welcoming and reasonably priced, the diner serves Hawaiian Japanese comfort food. The set meals are the best value, a sampling of small dishes that might include sashimi, sukiyaki, fried fish, rice, and sides of cucumber, cabbage, and miso soup. The ahi is excellent (and the wasabi so soft and fresh), but the restaurant is really known for its shrimp tempura: Every local we asked about Japanese food told us to try it here. You can get it on its own, or as part of the “deep sea trio” of shrimp tempura, fried fish, and sashimi.

While it’s tough to verify El Fenix’s claim that this was one of the forefathers of Tex-Mex, there’s no denying that the homegrown chain is as much a part of culinary history as it is of Dallas’s. Started in 1916 by Mexican-immigrant Mike Martinez (and renamed El Fenix in 1918, as a nod to the phoenix, a symbol of rebirth), the original café first served standard American fare, then slowly began introducing more “exotic” Mexican flavors, then combination platters that featured both cuisines—thus was born Tex-Mex, El Fenix style. Generations of Dallasites have grown up with signature dishes like the homemade chile con queso dip, cheese or sour cream chicken enchiladas, and legendary tortilla soup, which is loaded up with crispy tortilla strips and chunks of cheese and avocado. As at the beginning, you’ll find American dishes with a Mexican twist, too, like cheeseburgers topped with Monterey Jack cheese, pico de gallo, and guacamole. The combination platters are particularly popular, as are the lunch specials. Though there are now over 20 locations all over the Metroplex, the downtown and North Dallas spots are notable for their long histories and old-school vibe—and for the real feeling you get that many of your fellow diners have been El Fenix regulars their whole lives. You might even spot a famous face among them, as the casual restaurants are a popular stop for visiting celebs, musicians, and pro athletes; Mick Jagger was even known to pop in when he was dating Dallas girl Jerry Hall.

This national park is an ecological preserve with upland watersheds, mangrove forests, and estuarine and marine environments that support threatened and endangered species. The park also includes the Columbus Landing Site, a National Historic Landmark that is the only known place where members of a 1493 expedition led by Christopher Columbus (his second voyage) set foot on what is now United States territory. Columbus and his men met a tribe of Caribs here, so it was the first documented encounter between American Indians and Europeans.

Store Bay, just outside Scarborough, is one of Tobago’s most popular beaches. Reserve some time after your swim for a visit to the dozens of bright and cheery craft shops and food stalls that make up the Store Bay Beach Facility. Need souvenirs? Browse for island crafts like batik, sandals, jewelry and items carved from wood and coconut shells.

Brought to you by the fine-dining folks at the gourmet-minded State Capital Kitchen, this highly touted food truck called Gnar (short for gnarly, or awesome) carries farm-fresh delights from chefs Arthur Martel and Mark Connell. Decked out in artist David Santiago’s fierce female-centric portraits, the tiny kitchen doles out affordable grub like stuffed waffle-pressed sopaipillas or Wagyu beef burgers alongside heaping bowls of pho. Afterward, wash everything down with thick chocolate, vanilla, or strawberry milkshakes.

The Shanghai Museum of Glass, housed in a former glassmaking factory, features ancient artifacts such as blown-glass hairpins from the Song Dynasty as well as modern glass sculptures by Chinese and international artists, many of them American. Take a glassblowing workshop and make a vase to bring home. 685 Changjiang Xi Lu, 86/(0) 21-6618-1970.