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Elevate the normally mundane experience of shopping for medicine-cabinet basics like soap and toothpaste with a visit to one of the oldest pharmacies in the world. In this 13th-century chapel with early Renaissance frescoes, Gothic carved wooden cabinets, and crystal chandeliers, most items are still crafted according to formulas originally created by Dominican monks. A small museum displays equipment once used to make Santa Maria Novella products, as well as a collection of beautifully painted ceramic jars that held the herbs and powders. Linger a little longer in this fragrant world by ordering a pot of herbal tea or a small glass of one of the historic liqueurs in the tearoom.

As the name suggests, this 37-acre Santa Barbara garden is horticultural heaven. For more than 43 years, socialite and opera singer Madame Ganna Walska filled the grounds with more than 3,000 plants; after her death, Lotusland opened to the public in 1993 as a nonprofit botanical garden. The species of plants hail from all over the world, and the collection includes succulents, aloes, ferns, bromeliads, and water lilies. Other gardens are planted by theme, like the Blue Garden, Theatre Garden, and Water Garden. There’s never a bad time to visit, but if you’re especially interested in seeing the lotuses bloom, mark July and August in your calendar. Nonmember visitors must make reservations in advance for two-hour tours that include both horticultural and historical information, but the parties are small, so you’ll have a clear view of the gardens. If you want the luxury of wandering the gardens unattended, consider purchasing a membership. Either way, be sure to stop at the garden shop for plants and tools, and dream about creating your own little Lotusland at home.

Superlatives abound at the InterContinental Los Angeles Downtown. The 73-story structure is the tallest building west of Chicago and, at 889 rooms, the largest InterContinental in the Americas. Opened in 2017, the hotel was also downtown’s first LEED Gold Certified building for Building Design and Construction. All that record setting is matched by a big personality and plenty of luxury, too. Inspired by architectural historian Reyner Banham’s book Los Angeles: The Architecture of Four Ecologies, the hotel features light fixtures based on schematic maps of L.A.’s freeways, hand-painted murals, and billboard-style headboards with city scenes.

Club Level suites are stocked with Le Labo Santal 33 amenities, customized with guests’ names. And on the 71st floor, bathrooms are cheekily decorated in Marie Antoinette and cowboy themes. The Versailles-inspired restaurant La Boucherie is an American steakhouse with a French twist. In the restaurant’s VIP Starlight Booths, diners enjoy wine-paired chef’s tasting menus along with jaw-dropping views. Another restaurant, Sora, is the place for intimate Japanese omakase. Be sure to order the 1100 Feet—an original blend of liqueurs reflective of L.A.’s confluence of cultures—at Spire 73, the Western Hemisphere’s highest open-air bar. Pro tip: Book the Presidential Suite, and you’ll be rewarded with another kind of epic view—an infinity bathtub that fills from the ceiling.

Parque de los Novios, in the center of Santa Marta’s colonial sector, is perfect for people-watching in the late afternoons when the tropical heat abates. Everyone from the gentry to the common folk—not to mention a plethora of brides posing beneath the gazebo—seems to treat themselves to a nice stroll around the park. Nearby restaurants and bars come alive after night falls, as do, of course, street artists and musicians.

Colombians from the Caribbean coast, known as Costeños, are immensely proud of their cultural, musical, literary, and historical heritage, all of which are on display at this interactive museum. The country’s famous shore stretches from the jungles bordering Panama up through the historic cities of Cartagena, Barranquilla, and Santa Marta, all the way to the deserts of La Guajira. Multimedia exhibits here offer insight into the region’s indigenous cultures, and into the varied musical expressions that have emerged along the long coastline.

The village of Monticello just outside of L’Île-Rousse would be worth a visit just for its wonderful coastal views, which come courtesy of its perch 213 meters (700 feet) above the sea. Like many towns here in the Balagne region it’s also known for a gorgeous church: Saint-François-Xavier, which has two fine Baroque chapels. Further down a mountain road that passes through groves of olive trees, Santa-Reparata is a village with another handful of historic churches and chapels.

A short hour’s drive from Santa Fe sits the sulfur-free mineral rich waters of Ojo Caliente Mineral Springs Resort & Spa. Sit and soak in temperatures of 80-105 degrees, and let all tensions melt away. Shhh, keep conversations low, most of the areas are in “whisper” zones.

An active parish of the Roman Catholic Diocese of San Diego, Mission Basilica San Diego de Alcalá remains a tranquil place of worship and reflection. Regardless of your religious beliefs, the first of California’s 21 missions is well worth a visit for its extensive history. It was originally constructed in Presidio Park in 1769 but moved inland to its current site just five years later. Records show that it was the first place in California to cultivate olives; tree cuttings from this mission would later be used to found olive groves at other missions around the state. It’s also home to the grave of Father Luis Jayme, the state’s first Catholic martyr; he was killed when American Indians stormed the mission in 1775 and is now buried next to the altar. Destroyed many times over, the mission was most recently rebuilt in the 1930s, but looks as it would have in the early 1800s.

Few restaurants more than 150 years old can be called trendy, but in innovation-crazy San Francisco, there is novelty in the classics, and Tadich Grill is the classic. The late Chronicle columnist and unabashed San Francisco-lover Herb Caen was also a frequent visitor. There’s a martini named after him, made with vodka, or as he called it, Vitamin V. The serious nature of the restaurant’s wood paneling, brass fixtures, and waiters in starched white aprons is matched by the food. No need to tinker with classic recipes for fried sand dabs or crab Louie, and the oysters and Hangtown fry are fine the way they have always been. The cioppino is by far the most popular dish on the menu, with about 27,000 bowls dished out a year. People come to Tadich Grill because they know what they’re getting: friendly service, great seafood, and a taste of San Francisco itself.

Starting in 2014, this collection of historic buildings was reinvented as a gastronomic hub—helping to revitalize the city’s downtown in the process. An early 20th-century citrus packing warehouse became the Anaheim Packing House, a virtual United Nations of food: Walking through the 42,000-square-foot hall, you’ll find citrusy ceviche at Urbana, fried chicken sandwiches at Sweetbird, garden-fresh hot pot at Rolling Boil, organic curry at ADYA, and matcha shaved snow at I Am. Craft beer—quickly becoming a signature of Southern California—is in no short supply, thanks to bars like Anaheim Brewery, housed inside a 1925 mission revival building. A circa 1917 marmalade factory became the MAKE Building, where you can linger over a flight of California reds at Pali Wine Co. or a plate of pulled pork at Jav’s Barbecue. The compact district is distinctly Californian, from the succulents and air plants inside to the palm trees and olive groves of Farmers Park outside—a grassy knoll where, at any given time, you might happen upon a free yoga class, a gardening demo, or a live acoustic band playing under the sun.

California’s original Holiday Inn has come a long way. After several iterations—former owners include singer Gene Autry and producer Merv Griffin—the property reopened as Parker Palm Springs in 2004. The hotel underwent a major refresh in 2017, with designer Jonathan Adler combining an electric color palette with irreverent, stylish details like an antique DRUGS pharmacy sign and a full wall of macramé owls. Couples love the rooms featuring private outdoor patios and hammocks that hang above their own sandpits. The 12 stand-alone villas work best for families. But the many shared spaces are what make this a Palm Springs playground for all ages: Wandering around the 13-acre grounds, you’ll encounter a life-sized chess set, a labyrinth of bougainvillea-lined garden paths, three pools (one is adults only), and hanging rattan chairs aplenty. The food ranges from breakfast all day at the upscale diner Norma’s to escargot and steak au poivre at the hushed French restaurant Mister Parker’s. Escape the activity on the ground at the Palm Springs Yacht Club spa, where every treatment is customized and you can easily spend an entire day.

The largely French-inspired menu at Republique has more than a few surprises on it, like the generous selection of oysters and kanpachi crudo in Thai green curry and peanuts. The high ceilings, walls of windows, and loads of natural light make the atmosphere ideal, as the omnipresent line outside suggests. The grilled octopus salad—made with cabbage, Santa Barbara pistachios, chile, citrus, and lime—is a must. Brunch, however, is the real draw. The brioche French toast is doused in Vermont maple syrup; pupusas come with Oaxacan cheese, avocado, a fried egg, and roasted poblano; and the kimchi fried rice is dished up with beef short ribs and eggs.

While staying in Mumbai, aka the entertainment capital of India, Chelsea Handler made time for a Bollywood class at Dance Planet, where she learned “classic moves like the Thumka, the hip-bopping move you see in movies like Slumdog Millionaire.” She learned from the best: Dance Planet’s instructors work with Bollywood dancers. “Bollywood is hard; you have to sing, act, and dance—kind of like Britney Spears,” Chelsea said. “I’m uncoordinated and have no rhythm, so it was very entertaining to try and mimic the woman who teaches many of the Bollywood actresses how to dance.” This appeared in the July/August 2017 issue.

Chef Nyesha Arrington’s personality may have won her fans on Top Chef years back, but it’s her talent in the kitchen that shot her to success at various Michelin-starred restaurants. With Native, which opened in late 2017, she brings together Los Angeles’s diverse influences and cultures through food. Pastrami from local Langer’s deli inspired her roast duck breast with pastrami jus and marble rye tuile; her Wagyu beef tartare seasoned with Aisoon sauce was named for her Korean grandmother. Enthusiastic waiters—many of whom go the extra mile by getting to know diners by name—may suggest favorites such as chestnut spaghetti with shiitakes and burrata, or even a secret item like a super-tender steak when available. As with Arrington’s cuisine, the 95-seat restaurant is approachable yet elevated, with rich honey-hued wood, brass, and a touch of marble. Don’t miss weekend brunch for the crazy-sounding but addictive kimchi latkes, as well as the coconut brown butter pancakes. Pro tip: If you can’t make it for a sit-down dinner, come to bar during Community Hour, daily from 5:30 to 7 p.m., and ask for the off-menu burger along with your rum-based cocktail Right by the Beach, served in a coconut.

Occupying a 1927 firehouse that was functioning until 1980, this nine-room hotel from the team behind Los Feliz’s Hotel Covell heralds a new era for downtown L.A.’s warehouse-cum-arts-district. The neighborhood’s first boutique hotel, the Firehouse boasts several original details, from concrete floors and exposed wood-truss ceilings to pressed-tin panels and niches originally built to hold statuettes of the Virgin Mary that were intended to protect firefighters. Even the massive red doors that once ushered in fire engines are still intact, though today they open to a light-filled ground floor that houses a café, bar, and restaurant led by chef Ashley Abodeely and pastry chef Rose Lawrence. Also on the ground floor is a retail shop with a curated selection of wares created exclusively for the hotel by L.A.-based designers, including robes and striped tote bags by Clare V, bandanas and pillowcases by Block Shop, apparel by culinary brand Hedley & Bennett, serving pieces by ceramicist Robert Siegel, and furniture from ETC.etera.