From Rome’s Leonardo Da Vinci-Fiumicino Airport—the largest in Italy—there are many ways to get to the center of the Eternal City, including by taxi. (They all charge a city-mandated flat fare of €48 for trips within the bounds of the ancient city walls.) It helps to familiarize yourself with your hotel’s location before arrival. You can also come by train; national rail connections arrive at Stazione Termini, while the newly launched, privately owned Italo Train service arrives at Stazione Tiburtina.
Rome is a very walkable city and also has several public transportation options, including a limited metro system and dozens of bus lines. Taxis are readily available, but they must be caught from a taxi stand or booked by phone—it’s not customary to hail cabs in the street.