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Little-known fact: New Orleans was the first place in North America to license pharmacists (starting in 1769, when the city was still under Spanish rule). After Louisiana became a territory, the U.S. governor extended the requirement, also decreeing that pharmacists take a three-hour licensing exam in order to practice. And no wonder illness got such attention—the city was arguably the least healthy place to live on the continent; it was riddled with yellow fever, malaria, and dysentery. This dark but fascinating history is explored in this atmospheric 1822 town house, which was once the home and shop of Louis J. Dufilho, the first licensed pharmacist in the city—and hence in the country. Exhibits include apothecary jars, tools of the trade, and leeches. (Yes. Leeches.)

Designated a UNESCO World Heritage Site, the Red Fort, located in New Delhi, is a treasure trove of cultural history. You can spend hours wandering among the various buildings, learning much about the history of India. Tucked away within the walls of the Red Fort is the Hall of Public Audience. Don’t be fooled by the modest red exterior, for once you cross the threshold you are greeted by intricately detailed inlaid-paneled walls that run from the floor to the canopy-ceiling. It is within this chamber that the emperor would receive people from the community and hear their complaints. (I entered this building to whine about the 104-degree heat, but alas, there was no emperor available, as it was far too hot.)

Could there be a more glorious setting for a cheese’s origin? These pastures surrounding a hilltop village (Gruyères) crowned with a castle (the Château de Gruyères), happy Swiss cows grazing with views of the Alps all around, producing the milk which, in time, arrives on grocery shelves as cheese around the world, stamped ‘GRUYÈRE’...and there’s a geometric garden in the castle’s courtyard, too.

By far the most recognizable landmark in the city’s skyline, the TV tower is the tallest structure in Berlin, and in Western Europe as well. The 1,207-foot transmitter, built during the 1960s, was a source of pride for East Germany, though over time it has become synonymous with the New Berlin values of tolerance, creativity, and independence. The 656-foot observation platform—reached by a fast elevator—offers views of up to 50 miles on a clear day; it also has a slowly revolving restaurant, Sphere. Because the tower receives around a million visitors annually, it’s worth buying a Fast Track premium ticket online so that you can skip the lines. A shop in the tower’s base sells posters, T-shirts, and other accoutrements featuring the iconic tower.

Amsterdam’s State Museum reopened in 2013 after a decade of renovations, and it is oh so worth a visit! Weave your way through the museum’s vast assemblage of historic art (there are over 8,000 pieces!) to check out works from Dutch masters such as Rembrandt, Van Dyck, and Vermeer in person. The collection’s best-known and most prominently displayed piece is Rembrandt’s Night Watch, but visitors can find everything from sculptures to artifacts from both the Netherlands and Dutch-colonial territories around the world. Opt for the multimedia tour for a special surprise.

Reservations required—and no wonder. The tours at the Neon Museum sell out months in advance. A walk through the museum’s famous “Boneyard” (where neon goes to die) is fascinating, from motel row to the first integrated casino (one that shut almost as soon as it opened), and the Stardust, with its nuclear testing-inspired font. All of this comes alive thanks to the museum’s famous docents, all art history buffs with loads of family history or other personal anecdotes.

The tram gives Portland visitors stunning views of the city, river, and mountains beyond. Grab the streetcar from downtown out to the waterfront. You’re delivered to the lower terminal for the three-minute ride carrying you 3,300 feet at 20 MPH to the upper terminal at OHSU. Linger for photo ops then head back down to explore. If it’s nice, skip the streetcar and walk back along the river. Daily workout, check. Roundtrip cost: $4. At the lower terminal, the Daily Cafe is an easy find in the atrium of the OHSU Clinical building as you disembark the pill-shaped car, built with precision by the Swiss. Head for the river and stroll along the shore in any weather. Double back along SW Bond Ave and consider lunch at Bambuza Vietnamese Bistro. Check out the pricey high-rise condos on the market in the real estate office windows, then relax in one of the pocket parks to people watch. It snows in Portland. A couple of times a winter, even downtown gets dusted and it’s a huge mess. I’ve dreamed about getting my ski gear on, grabbing my boards and heading for the PDX Tram at the South Waterfront. I’d casually climb aboard with the patients and medical folks heading up to “Pill Hill” and blow their minds.

The sky above Jasper National Park comes alive at night. Celebrated as a Dark Sky Preserve, the national park is one of the best places in the world to stargaze. Light pollution is that orange hue often seen above cities, which is caused by the large amount of iridescent light omnipresent in populated areas. Jasper, home to only 5,000 people in a 10,000-square-kilometer area, is essentially light-pollution free. Because of this, the skies are darker—the area around Columbia Icefield is one of the darkest places in North America—so it’s possible to clearly see more stars than nearly anywhere else. Although the dark skies are best viewed in autumn and winter, from September to March, the best time to learn about the stars is during Jasper’s annual Dark Sky Festival that takes place at the end of October. The best part? It’s absolutely free.

In a city where gold-spired temples are much more ubiquitous than green space, Lumphini Park is a veritable oasis in the heart of Bangkok. Established by King Rama VI in the 1920s and completed after his death, the 142-acre chunk of tropical greenery is a treasured spot. One of the few parks of any size in central Bangkok, Lumphini is well used: In the morning, tai chi practicers arrive, while in the early evening, joggers monopolize the main path that runs around its perimeter. Even so, there’s ample room to get away from the crowds here. More than 30 species of birds flit among the park’s giant trees, and monitor lizards and turtles inhabit its waterways. Other attractions within the park include a public library, a youth sports center, and swan paddleboats in the man-made lake.

New Orleans’s newest public park lies along about a mile and a half of the Mississippi River—a lovely retreat reclaimed from industrial squalor. The main entrance is near the foot of Esplanade Avenue, marked by a boxy footbridge (with elevator) over the railroad tracks, which divide the park from nearby low-slung neighborhoods. While walking along the water, note how the powerful Mississippi’s twists and currents require dexterity from a river pilot, as the huge passing barges slide past sideways angling for the bends. At Piety Wharf—a former warehouse location converted into a massive sculpture that invites contemplation—you can cross a steeply arched span (designed by noted architect David Adjaye, and locally dubbed the Rusty Rainbow) into the Bywater neighborhood for a walk back to the French Quarter.

Still in use today, the Ifugao Rice Terraces were carved into the hillsides of Ifugao Province by hand some 2,000 years ago, and are fed by an elaborate irrigation system that captures water from the forests above. While many people explore this famed landscape from the town of Banaue, the Banaue Rice Terraces cluster here isn’t technically part of the Rice Terraces of the Philippine Cordilleras UNESCO World Heritage site. These terraces are, however, designated a National Cultural Treasure by the Philippine government and are undeniably spectacular. But probably the most impressive of all the terraces are at Batad, a tiny, remote village in the municipality of Banaue that is only accessible by foot. Thanks to their pristine condition, these terraces—along with four other clusters—are included in the UNESCO inscription. The reward for your hike up is a panorama of a kind of enormous amphitheater where each level is actually a rice paddy and where the village of Batad takes the place of the central stage at its base. Maximize your experience by staying in one of the indigenous huts and wake up to a view of the terraces before you even get out of your cot.

Many who have not visited Arizona think that its saguaros grow in a Sahara-like setting...but the mountainous desert around Tucson hides many lush spots, like this riparian canyon on the NE edge of the city. Late fall paints the cottonwoods along the creek below cactus-studded slopes in Sabino Canyon. Hikers hike, runners run, and deer roam...

It’s easy to stay health-focused, even on vacation, if you stop by the Lemon Press. This adorable space in the middle of town has fresh cold-pressed juices and super smoothies. Liquid Sunshine is a winning combination of mango, peach, and organic apple juice. And if you are looking for damage control from the previous evening, try the Scenic Root or Georgia Green. Both will help you get back on track. Also on the menu are delicious sandwiches and photo-worthy toasts.

Of all the reasons to hike in B.C.’s Coast Range, visiting a train wreck would not rank high elsewhere. This is Whistler, though, where a train derailment becomes a canvas for artists and a must-see novelty that remains well off the beaten track (sorry!), even for many locals. A new bridge spanning the Cheakamus River makes the hike legal and considerably less treacherous. The trail’s steel-meets-seedlings design is reminiscent of New York City’s High Line, and among the many spurs are a boardwalk into the coastal rain forest and a longer trek that leads to the Sea to Sky Trail. Once a hush-hush locale for graffiti artists and mountain bikers, the Train Wreck hike and suspension bridge route are now well-marked at the Sea to Sky trailhead, just outside of Function Junction.

Stepping into the enormous main concourse of this landmarked architectural jewel—with its sweeping granite staircases, hulking columns and 38-meter (125-foot) ceilings painted with night-sky constellations—can be a jaw-dropping experience. What’s even more incredible, though, is the sheer number of people who use it as a commuter hub day in and day out (more than 750,000 train and subway passengers every weekday). Wander around the shops, head down to the basement food court for a bite and to marvel at the crowds hurrying by—and if you get jostled, don’t take it personally.