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Wine bars, craft beers, cocktail bars: Rome will quench your thirst in the most delicious of ways. Whether you choose to do your people watching at the Stravinskij Bar at the Hotel de Russie, the Jerry Thomas Speakeasy, or a spot far more relaxed, you can’t go wrong. Though Italy, of course, usually puts people in a wine mind, Rome goes big on craft beers at spots like Ma Che Siete Venuti.

In remote Africa, travelers find profound stillness, untamed nature, and a portal to the past. Don’t forget the gin and tonics.

Tourism is down, prices are up, social services are disappearing, and the government is bankrupt. Which means it’s a good time to get to know Seychelles.

A glimpse at the future of this important South African metropolis, according to the creatives who are shaping it.

This two-auditorium space—with adjacent performance venues—is a lot more than simply a place to catch great concerts. Part of Parque de los Deseos and constructed opposite the city’s planetarium, it emerged from a citizen initiative meant to reanimate Medellín’s social and cultural life. The idea is to foment learning and create awareness about various musical disciplines. It offers a number of free musical and dance training programs; children’s orchestras from underserved neighborhoods also present memorable open-air recitals here. Casa de la Música is one part of an equation that, little by little, has allowed life to improve in complex and marvelous Medellín.

Happy hour is a beloved D.C. institution, and there are storied bars like Jack Rose as well as newer hot spots where you can raise a (discounted) glass with locals. As with restaurants, the nightlife scene has gotten better and more varied in recent years. Head to trendy areas like the U Street Corridor and 14th Street for creative cocktails, sleek wine bars, and craft beer. For live music, try a jazz club in Georgetown or eclectic favorite venues in Adams Morgan.

Athens is infused with counterculture, ranging from the anarchic and graffitied to global-nomad hipster. Bohemia tends to concentrate in a few neighborhoods, notably Exarchia, Kerameikos, Metaxourgeio and the road leading toward Pireaus, but street art and edgy eateries can dot even posher neighborhoods. Of note are Athens’ many wonderful collective DIY art venues combining nightlife, music, art, performance and sometimes even daytime work.

Born free, today’s post-apartheid generation asks, what’s next?

In the past decade or so, Budapest’s restaurant scene has broadened beyond goulash and stuffed cabbage, with trendy new venues serving both a wider variety of international cuisines and elegant, innovative takes on traditional Hungarian fare.

AFAR chose a destination at random—by literally spinning a globe—and sent writer Ryan Knighton to Egypt’s sprawling capital with just 24 hours’ notice.

AFAR chose a destination at random—by literally spinning a globe—and sent Scott Hocker on a spontaneous journey to Croatia.

AFAR chose a destination at random—by literally spinning a globe—and sent writer Jonathan Gold on a spontaneous journey to Prague with just 24 hours’ notice.

Istanbul has a rocking nightlife that spans both continents and all hours of the evening—and early morning. While options for wild nights are limited in the tourism precinct of Sultanahmet, the beats pick up across the Golden Horn in the Beyoğlu District with rock, alternative, and world music venues along the side streets off Istiklal Caddesi. For supper clubs and VIP style, head to Ortaköy or Kuruçeşme to party by the Bosporus.

Greeks, especially Athenians, are high-spirited partiers, and don’t stop till they get enough. For those seeking glamour it’s fun to sip cocktails on a rooftop bar, but it’s just as fun to dance in a grungy music venue. Wander near the Technopolis in Gazi or the clubs near the sea during summer, when the party simply spills out onto the streets. Start late, and pace yourself until sunrise, which is when most locals only begin to think about going home.

Witnessing ceremonies of love take place around the world can reveal some pretty profound life lessons.